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Unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection in Stage II non-seminomatous germ cell tumor:A tertiary care experience

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Asian Journal of Urology 2023年第4期10卷 440-445页

作者： Dario Franzese Antonio Tufano Alessandro Izzo Raffaele Muscariello Giovanni Grimaldi Giuseppe Quarto Luigi Castaldo Sabrina Rossetti Savio Domenico Pandolfo Sonia Desicato Paola Del Prete Matteo Ferro Sandro Pignata sisto perdonà Department of Urology National Cancer InstitutePascale FoundationNaplesItaly Urology Unit Department of Maternal-Child and Urological Sciences“Sapienza”UniversityRomeItaly Department of Neurosciences Science of Reproduction and OdontostomatologyUniversity of Naples Federico IINaplesItaly Scientific Directorate Istituto Nazionale Tumori di NapoliIRCCS“G.Pascale”NaplesItaly Division of Urology European Institute of Oncology(IEO)IRCCSMilanItaly Division of Medical Oncology Department of Uro-Gynaecological OncologyIstituto Nazionale per lo Studio e la Cura dei Tumori“Fondazione G.Pascale”IRCCSNaplesItaly

Objective Post-chemotherapy retroperitoneal lymph node dissection(PC-RPLND)represents an integral component of the management of patients with non-seminomatous germ cell tumor(NSGCT).Modified templates have been proposed to minimize the surgical morbidity of the ***,the implementation of robotic surgery in this setting has been *** report our experience with unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection(PC-rRPLND)for clinical Stages IIA and IIB *** A retrospective single institution review was performed including 33 patients undergoing PC-rRPLND for Stages IIA and IIB NSGCTs between January 2015 and February *** orchiectomy,patients were scheduled for chemotherapy with three cycles of *** with a residual tumor of<5 cm and an ipsilateral metastatic disease on pre-and post-chemotherapy CT scans were eligible for a unilateral template in absence of rising tumor *** statistics were provided for demographics,clinical characteristics,intraoperative and postoperative ***,oncological,and functional outcomes were *** Overall,7(21.2%)patients exhibited necrosis or fibrosis;14(42.4%)had mature teratoma;and 12(36.4%)had viable tumor at final *** median lymph node size at surgery was 25(interquartile range[IQR]21-36)*** operative time was 180(IQR 165-215)min and no major postoperative complications were *** ejaculation was preserved in 75.8%of *** follow-up was 26(IQR 19-30)months and a total of three recurrences were *** PC-rRPLND is a reliable and technically reproducible procedure with safe oncological outcomes and acceptable postoperative ejaculatory function in well selected patients with NSGCTs.

关键词： Testis tumor Robot-assisted retroperitoneal lymph node dissection Retroperitoneal lymph node dissection Non-seminomatous germ cell tumor Unilateral dissection Modified template Post-chemotherapy

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A systematic review of robot-assisted partial nephrectomy outcomes for advanced indications:Large tumors(cT2-T3),solitary kidney,completely endophytic,hilar,recurrent,and multiple renal tumors

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Asian Journal of Urology 2023年第4期10卷 390-406页

作者： Savio Domenico Pandolfo Clara Cerrato Zhenjie Wu Antonio Franco Francesco Del Giudice Alessandro Sciarra Paolo Verze Giuseppe Lucarelli Ciro Imbimbo sisto perdonà Edward E.Cherullo Francesco Porpiglia Ithaar H.Derweesh Riccardo Autorino Department of Urology Rush University Medical CenterChicagoILUSA Department of Neurosciences Reproductive Sciences and Odontostomatology“Federico II”UniversityNaplesItaly Department of Urology University of VeronaVeronaItaly Department of Urology Changhai HospitalNaval Medical UniversityShanghaiChina European Association of Urology(EAU)Young Academic Urologists(YAU)Renal Cancer Working Group Arnhemthe Netherlands Department of Urology Sant’Andrea HospitalLa Sapienza UniversityRomeItaly Department of Maternal-Infant and Urologic Sciences La Sapienza UniversityPoliclinico Umberto I HospitalRomeItaly Department of Medicine and Surgery Scuola Medica SalernitanaUniversity of SalernoFiscianoItaly Department of Emergency and Organ Transplantation-Urology Andrology and Kidney Transplantation UnitUniversity of BariBariItaly Department Uro-Gynecology IRCCS G.Pascale FoundationNaplesItaly Department of Urology San Luigi Gonzaga HospitalUniversity of TurinOrbassanoItaly Department of Urology University of California San DiegoLa JollaCAUSA

Objective:Robot-assisted partial nephrectomy(RAPN)has become widely used for treatment of renal cell carcinoma and it is expanding in the field of complex renal *** aim of this systematic review was to analyze outcomes of RAPN for completely endophytic renal masses,large tumors(cT2-T3),renal cell carcinoma in solitary kidney,recurrent tumors,completely endophytic and hilar masses,and simultaneous and multiple ***:A comprehensive search in the PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials databases was performed in December 2022 for English language *** primary endpoint was to evaluate the role of RAPN in the setting of each category of complex renal masses *** secondary endpoint was to evaluate the surgical and functional ***:After screening 1250 records,43 full-text manuscripts were selected,comprising over 8500 *** and thirteen studies reported data for endophytic and hilar renal masses,*** and three studies reported outcomes for cT2-T3 and solitary kidney patients,*** studies focused on redo-RAPN for recurrent *** studies investigated simultaneous bilateral renal masses and five reports focused on multiple tumor excision in ipsilateral ***:Over the past decade,evidence supporting the use of RAPN for the most challenging nephron-sparing surgery indications has continuously *** limitations remain including study design and lack of detailed long-term functional and oncological outcomes,the adoption of RAPN for the included advanced indications is associated with favorable surgical outcomes with good preservation of renal function without compromising the oncological ***,a higher likelihood of complication might be expected when facing extremely challenging ***,none of these indications should be considered per se an exclusion criterion for performing ***,a risk-adapted approach s

关键词： Robot-assisted partial nephrectomy Complex renal mass Solitary kidney Larger tumors(cT2-T3) Endophytic and hilar mass Recurrent tumor Simultaneous and multiple tumor

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Sarcopenia in heart failure： mechanisms and therapeutic strategies

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Journal of Geriatric Cardiology 2016年第7期13卷 615-624页

作者： Agnese Collamati Emanuele Marzetti Riccardo Calvani Matteo Tosato Emanuela D'Angelo Alex N sisto Francesco Landi Center for Geriatric Medicine (CEMI) Institute of Internal Medicine and Geriatrics Catholic University of the Sacred Heart Rome Italy

长期的心失败(CHF ) 是一个高度流行的条件在之中老并且与可观的病态， institutionalization 和死亡被联系。在它的先进阶段， CHF 被肌肉质量和力量的损失经常伴随。Sarcopenia 是活跃地与大量不利健康结果由于它的协会在最近的年里... 详细信息

长期的心失败(CHF ) 是一个高度流行的条件在之中老并且与可观的病态， institutionalization 和死亡被联系。在它的先进阶段， CHF 被肌肉质量和力量的损失经常伴随。Sarcopenia 是活跃地与大量不利健康结果由于它的协会在最近的年里被学习了的衰老老人症候群。这评论的目标是讨论在 CHF 和 sarcopenia 之间的关系，与分享的 pathophysiological 小径和处理的一个焦点。营养不良，全身的发炎，内分泌的不平衡，和氧化应力看起来连接 sarcopenia 和 CHF。在肌肉发达的水平， ubiquitin proteasome 系统，发信号的 myostatin，和 apoptosis 的改变在 sarcopenia 和 CHF 被描述了并且能在肌肉质量和功能的损失起一个作用。阻碍肌肉在 CHF 病人浪费的前进的可能的治疗学的策略包括变换血管收缩素的酶禁止者和 β 的蛋白质和维生素 D 补充，结构化的物理锻练，和管理； -blockers。有生长荷尔蒙，睾丸激素，和 ghrelin 的神经质的补充也作为潜在的治疗被讨论。

关键词： Ghrelin 肌肉损失蛋白质补充维生素 D

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Comparison of perioperative parameters in one-handed rotational phacoemulsification versus conventional phacoemulsification and femtosecond laser-assisted cataract surgery

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International Journal of Ophthalmology(English edition) 2021年第12期14卷 1868-1875页

作者： Samuele Gigliola Giancarlo Sborgia Alfredo Niro Carmela Palmisano Pasquale Puzo Gianluigi Giuliani Luigi Sborgia Dario sisto Valentina Pastore Claudio Furino Rossella Donghia Alessandra Sborgia Francesco Boscia Giovanni Alessio Eye Clinic Department of Medical ScienceNeuroscience and Sense OrgansUniversity of BariBari 70124Italy Eye Clinic Hospital“SS.Annunziata”ASL TarantoTaranto 74121Italy National Institute of Gastroenterology“S.de Bellis”Research Hospital Castellana Grotte 70013Italy

AIM:To compare perioperative parameters of one-handed rotational phacoemulsification technique(one-handed phaco-roll)with each of other two techniques,“Divide et Conquer”and femtosecond laser-assisted cataract surgery(FLACS)METHODS:In this retrospective and comparative cohort study,eyes with uncomplicated cataract(nuclear density grade 2 to 3)treated routinely with one-handed phacoroll(n=23;Group 1)or“Divide et Conquer”(n=23;Group 2)or FLACS(n=23;Group 3)were *** parameters including effective phaco-time(EPt),ultrasound time(USt),aspiration time,surgical time,phacoemulsification(phaco)-power,balanced salt solution(BSS)use,cumulative dissipated energy(CDE)were recorded and *** outcomes including best corrected visual acuity(BCVA),corneal endothelial cell density(ECD),endothelial cell loss(ECL),central corneal thickness(CCT)and central macular thickness(CMT),were assessed and compared pre-operatively and at 1mo after ***:Aspiration and surgical time,and BSS used were lower in Group 1(P<0.01)than other ***,phaco-power and CDE were lower in Group 1(P<0.05)than Group 2 but not significantly different from Group *** Group 1,USt was lower(P<0.05)than Group 2 but higher(P<0.05)than Group *** improved in all groups without significant difference between Group 1 and the other *** significant differences regarding all post-operative morphologic outcomes(ECD,ECL,CCT,CMT)were *** clinical complications ***:One-handed phaco-roll seems to be less time-consuming than“Divide et Conquer”and FLACS and less energy-consuming than“Divide et Conquer”.Furthermore,one-handed phaco-roll seems to have an equal safety profile compared to the other two techniques.

关键词： cataract surgery phaco-rolling onehanded phacoemulsification Divide et Conquer femtosecond laser-assisted cataract surgery

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BLOX综合体丹麦哥本哈根

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世界建筑导报 2022年第3期37卷 86-90页

作者： Clement Guillaume(摄影) Delfino sisto Legnani(摄影) Marco Cappelletti(摄影) Rasmus Hjortshøj(摄影) Hans Werlemann(摄影) Rich Seymour(摄影) 不详

作为丹麦建筑中心的发源地,BLOX综合体项目包含展示空间、私人办公及联合办公区域、一家咖啡馆、一间书店、一间健身房、一家餐馆、22间公寓以及一个地下自动公共停车场,上述区域看似分离独立,如何连接以上功能区域,使之成为一个有机整... 详细信息

作为丹麦建筑中心的发源地,BLOX综合体项目包含展示空间、私人办公及联合办公区域、一家咖啡馆、一间书店、一间健身房、一家餐馆、22间公寓以及一个地下自动公共停车场,上述区域看似分离独立,如何连接以上功能区域,使之成为一个有机整体正是该项目设计的核心。此项目的终极目标就是在原有地址发现更多的美,进行二次开发。以哥本哈根主要环状路线为分界线,老啤酒厂区(Old Brewery)被分为两部分,起初老啤酒厂没有被认定为一个建筑,直到新的丹麦建筑中心设计方案完成,才将老啤酒厂认定为一个建筑。BLOX综合体横跨道路,把道路上下方的社交紧密联系起来,同时BLOX也把议会区域与港湾联系起来,将文化延伸至水的边缘。在地下,原本属于“汽车”的空间变成属于“人”的空间,通行空间变成可以驻留的空间。

关键词：办公区域功能区域公共停车场啤酒厂综合体健身房咖啡馆丹麦哥本哈根

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First Evidence of Fungal Strains Isolated and Identified from Naphtha Storage Tanks and Transporting Pipelines in Venezuelan Oil Facilities

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Advances in Microbiology 2015年第2期5卷 143-154页

作者： Leopoldo Naranjo Beatriz Pernía Ysvic Inojosa Diego Rojas Lucia Sena D’Anna Meralys González ángela De sisto Área de Energía y Ambiente Instituto de Estudios Avanzados (IDEA) Caracas Venezuela

Biocorrosion, as well as the biodeterioration of crude oil and its derivatives, is one of the major environmental, operational and economic problems in the Venezuelan oil industry. Fungal contaminants are able to produce large quantities of biomass and synthesize peroxides and organic acids, causing severe damage on metal surfaces and promoting the contamination and biodeterioration of fuels. No evidences regarding fungal strains have been reported to be associated to petroleum naphtha, widely used as a diluent of extra heavy crude oil (EHCO) in the exploitation processes of the Orinoco Oil Belt, the biggest proven reserve of EHCO worldwide. The aims of this paper were to isolate and identify fungal strains from the naphtha storage tank and the naphtha distribution network from an oil field operator in Venezuela. The results showed the isolation of four different fungal strains. The molecular identification by 28S rRNA sequencing and phylogenetic tree analysis allowed us to identify the presence of: 1) a new uncultured Ascomycota fungus species BM-103, with high identity to novel hyphomycetes Noosia banksiae and Sporidesmium tengii, in the naphtha storage tank;2) two yeasts, Rhodotorula mucilaginosa BM-104 (Phylum Basidiomycota) and Wickerhamia sp. BM-105 (Phylum Ascomycota), in a highly damaged naphtha pipeline branch and;3) Cladosporium cladosporioides BM-102 (Phylum Ascomycota) in a cluster oil well. DNA fingerprinting analysis using ERIC-PCR primers pairs also allowed us to detect the presence of R. mucilaginosa BM-104 right in the access of the studied naphtha system. Interestingly, R. mucilaginosa and C. cladosporioides were previously reported as predominant fungal contaminants of diesel and jet fuel and of kerosene and fuel storage systems, respectively. This paper represents the first evidence of fungal strains isolated and identified from the naphtha systems in the Venezuelan oil industry. The results obtained are discussed.

关键词： Fungi Biocorrosion Biodeterioration Naphtha Pipelines Extra Heavy Crude Oil Orinoco Oil Belt

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四号防空战车“旋风”早期生产型

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模型世界 2012年第12期 64-65页

作者： Frank V.De sisto Voss 不详

简介装备四联装20毫米Flak38炮的IV号防空战车有一段不寻常的来历。此车最早由一线部队使用返修的IV号战车底盘自行改装,威龙第一弹"旋风"战车就是以Ausf.H型底盘为基础的。第二弹则选用了Ausf.G型底盘,但没有敷设防磁涂层。现在,他们... 详细信息

简介装备四联装20毫米Flak38炮的IV号防空战车有一段不寻常的来历。此车最早由一线部队使用返修的IV号战车底盘自行改装,威龙第一弹"旋风"战车就是以Ausf.H型底盘为基础的。第二弹则选用了Ausf.G型底盘,但没有敷设防磁涂层。现在,他们推出了新添加的防磁装甲涂层和新的涂装方案,并选用DS材质履带的版本。由于威龙公司的通用模具策略,本套材包含了很多H型战车所使用的带防磁涂层的零件,包括上层车体以及炮盾等,使用这些富余零件替换玩家堆积的同型号不带防磁的IV号H型,可以节约不少自行敷设防磁的时间。

关键词：生产型防空战车水转印炮塔座圈负重轮附加装甲

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德军*** 10 Ausf B 1942年型半履带牵引车

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模型世界 2013年第2期 43-45页

作者： Frank V.De sisto 李煜

套件编号:6731基本描述:产品包含403个塑料射出零件(其中四个为透明件),两包魔术履带,一片蚀刻片,三种水贴和涂装方案,以及分14步的6页说明书。优点:很多小细节得到了完美再现,整车也较好地展现了原型车的特征。

关键词：挡泥板 Sd.Kfz 10 Ausf B 负重轮发动机舱驾驶室乘员舱

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塞纳河畔Nuba餐厅俱乐部

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现代装饰 2014年第6期 68-75页

作者： Emmanuel Picault Ludwig Godefroy Nicolas sisto 姜敏华 Chic By Accident、Ludwig Godefroy设计事务所 Nicolas sisto设计事务所

Nba坐落于美丽的塞纳河畔,占地约为1,400平方米且临近奥斯特利茨火车站。三位设计师Emmanuel Picault、Ludwig Godefroy和Nicolas Sist分别来自法国和墨西哥。俱乐部内饰与外观十分独特、大胆,既有法国的浪漫优雅,又有墨西哥的奔放。... 详细信息

Nba坐落于美丽的塞纳河畔,占地约为1,400平方米且临近奥斯特利茨火车站。三位设计师Emmanuel Picault、Ludwig Godefroy和Nicolas Sist分别来自法国和墨西哥。俱乐部内饰与外观十分独特、大胆,既有法国的浪漫优雅,又有墨西哥的奔放。室内以采用黑色和不同深浅的咖啡色材质为主,多件物件都来自墨西哥的纯手工制作,让人大为惊艳!简单而棱角分明的几何图案定义了该项目的基调,多件饰品来自墨西哥最好的纯手工制作。"在所有材料中,最值得一提的是我们从韦拉克鲁斯和勒阿弗尔市运来的5吨火山石和

关键词：塞纳河畔 ba 奥斯特利茨纯手工制作勒阿弗尔火山石 Emmanuel 瓜纳华托克鲁斯几何图案

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旅程的故事法国巴黎NüBA餐厅

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室内设计与装修 2014年第7期 26-27页

作者： Emmanuel Picault Ludwig Godefroy Nicolas sisto 贰陆

这间由墨西哥和法国两地设计师联合设计的餐厅就开设在巴黎塞纳河畔。餐厅的主人在墨西哥居住了许多年,室内的许多材料都是直接从墨西哥运送到法国的。将近5吨的火山岩从墨西哥港口城市韦拉克鲁斯运送到法国的勒阿弗尔,此外200 m2的皮... 详细信息

这间由墨西哥和法国两地设计师联合设计的餐厅就开设在巴黎塞纳河畔。餐厅的主人在墨西哥居住了许多年,室内的许多材料都是直接从墨西哥运送到法国的。将近5吨的火山岩从墨西哥港口城市韦拉克鲁斯运送到法国的勒阿弗尔,此外200 m2的皮革从墨西哥的瓜纳华托运至此处,用以装饰空间的墙面,还有来自Santa Clara Del Cobre的300 m2的铜质薄片被拿来装饰天花板。空间包含酒吧和餐厅两项功能。室内的几何形态带来了灵动的空间美感,营造一种神秘又高贵的氛围,让来此的顾客们得到一种非凡的感官体验。白天,这里就是一间普通的餐厅,到了晚上空间变身为酒吧,有乐队在此演奏。

关键词：法国巴黎餐厅装饰空间故事 BA 墨西哥 Clara 联合设计

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