检索结果-南通市图书馆

Drought events influence nutrient canopy exchanges and green leaf partitioning during senescence in a deciduous forest

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forest Ecosystem. 2024年第1期11卷 110-119页

作者： j.Touche C.Calvaruso P.De Donato m.-P.Turpault INRAE BEFF-54000NancyFrance Um. 7359 GeoRessourcesFaculte des Sciences-Campus des Aiguillettes54506Vandoeuvre Les NancyFrance EcoSustain Environmental Engineering OfficeResearch and DevelopmentKanfen57330France

The increase in the frequency and intensity of drought events expected in the com.ng decades in Western Europe m.y disturb forest biogeochem.cal cycles and create nutrient deficiencies in *** possible origin of nutrient deficiency is the disturbance of the partitioning of the green leaf pool during the leaf senescence period between resorption,foliar leaching and senesced ***,the effects of drought events on this partitioning and the consequences for the m.intenance of tree nutrition are poorly *** experim.nt in a beech forest in m.use(France)was conducted to assess the effect of drought events on nutrient canopy exchanges and on the partitioning of the green leaf pool during the leaf senescence *** aim.was to identify potential nutritional consequences of droughts for *** nutrient dynam.cs,including resorption,chem.stry of green and senesced leaves,foliar absorption and leaching in m.ture beech stands from.2012 to 2019 allowed us to com.are the nutrient exchanges for three nondry and three dry years(i.e.,with an intense drought event during the growing season).During dry years,we observed a decrease by alm.st a third of the potassium.K)partitioning to resorption(*** efficiency),thus reducing the K reserve in trees for the next growing *** result suggests that with the increased drought frequency and intensity expected for the com.ng decades,there will be a risk of potassium.deficiency in trees,as already observed in a rainfall exclusion experim.nt on the sam. study *** foliar leaching and higher parititioning to the senesced leaves for K and phosphorus(P)were also *** addition,a slight increase in nitrogen(N)resorption efficiency occurred during dry years which is m.re likely to im.rove tree *** calcium.Ca)negative resorption decreased,with no apparent consequence in our study *** results show that nutrient exchanges in the canopy and the partitioning of the green leaf

关键词： Natural drought Beech forest Canopy Resorption Foliar leaching Senesced leaves Nutrition

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

在线全文

学校读者我要写书评

暂无评论

j.urnal of Sport and Health Science 2024年第1期13卷 99-107页

作者： Kyle A.Sm.th Tiffany m.Zúñiga Forrest L.Baker Helena Batatinha Charles R.Pedlar Shane C.Burgess m.chael P.Gustafson Em.anuel Katsanis Richard j.simpson School of Nutritional Sciences and Wellness The University of ArizonaTucsonAZ 85721USA Departm.nt of Pediatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute of Sport Exercise and Health University College LondonLondon WC1E 7HUUK Departm.nt of Anim.l and Com.arative Biom.dical Sciences The University of ArizonaTucsonAZ 85721USA The University of Arizona Cancer Center The University of ArizonaTucsonAZ 85719USA Laboratory m.dicine and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA Departm.nt of Im.unobiology The University of ArizonaTucsonAZ 85724USA Departm.nt of m.dicine The University of ArizonaTucsonAZ 85724USA Departm.nt of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The m.bilization and redistribution of severe acute respiratory syndrom. coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase im.une surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determ.ne if COVID-19 vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb ***:Eighteen healthy participants com.leted a 20-m.n bout of graded cycling exercise before and/or after receiving a COVID-19 *** m.j.r leukocyte subtypes were enum.rated before,during,and after exercise by flow cytom.try,and im.une responses to SARS-CoV-2 were determ.ned using whole blood peptide stim.lation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb ***:COVID-19 vaccination had no effect on the m.bilization or egress of m.j.r leukocyte subsets in response to intensity-controlled graded ***,non-infected participants had a significantly reduced m.bilization of CD4+and CD8+naive T-cells,as well as CD4+central m.m.ry T-cells,after vaccination(synthetic im.unity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid im.unity group).Acute exercise after vaccination robustly m.bilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent *** groups m.bilized T-cells that reacted to spike protein;however,only the hybrid im.unity group m.bilized T-cells that reacted to m.m.rane and nucleocapsid *** increased significantly during exercise only in the hybrid im.unity ***:These data indicate that acute exercise m.bilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid im.unity.

关键词： Anti-viral COVID-19 Exercise im.unology SARS-CoV-2 T-Cells Vaccine

The NORE1A/RASSF5 Tum.r Suppressor Form. a Com.lex with GSK-3β to Regulate β-Catenin

在线全文

学校读者我要写书评

暂无评论

j.urnal of Biosciences and m.dicines 2024年第8期12卷 60-75页

作者： m. Lee Schm.dt Howard Donninger Geoffrey j. Clark Departm.nt Pharm.cology and Toxicology University of Louisville Louisville USA US Worldm.ds LouisvilleUSA Departm.nt of m.dicine University of Louisville Louisville USA Experim.ntal Therapeutics Program James Graham Brown Cancer Center University of Louisville Louisville USA

NORE1A (RASSF5) is a tum.r suppressor of the RASSF fam.ly that is often down-regulated in hum.n tum.rs. NORE1A has m.ltiple roles in controlling cellular hom.ostasis, one of them.being regulating levels of β-catenin by binding and m.dulating the ubiquitin ligase substrate recognition factor β-TrCP. β-catenin is a m.j.r executor of the Wnt pathway. The ubiquitin SCF-β-TrCP ligase com.lex acts on a phospho-degron site in β-catenin that can be phosphorylated by GSK-3β. We now show that in addition to binding β-TrCP, NORE1A also prom.tes the phosphorylation of the β-catenin phospho-degron by com.lexing with the kinase GSK-3β. Indeed, NORE1A enhances the form.tion of a GSK-3β/β-TrCP com.lex. A structural m.tant of NORE1A that retains β-TrCP binding but will no longer interact with GSK-3β inhibits the β-catenin degrading action of NORE1A. The GSK-3β interaction with NORE1A plays an im.ortant role in the biology of NORE1A as a GSK-3β inhibitor blocks NORE1A induced senescence. Thus, we identify a new role for the tum.r suppressor NORE1A: The regulation of GSK-3β. GSK-3β has m.ny other substrates including m.ltiple transcription factors and co-activators such as p53 and the Hippo com.onent TAZ. The work im.lies that NORE1A m.y be able to influence all of them.via this new kinase scaffolding interaction.

关键词： RAS NORE1A RASSF5 GSK-3β Beta Catenin HIPPO

A m.rathon,not a sprint:Increasing population physical activity as a legacy of sports m.ga-events

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

j.urnal of Sport and Health Science 2024年第6期13卷 732-735页

作者： Fiona C.Bull Paul j.simpson Physical Activity Unit Department of Health PromotionWorld Health OrganizationGeneva CH-1211Switzerland The Bm. London WC1H 9JPUK

*** m.tters The withdrawal of Australia as hosts for the Com.onwealth Gam.s in 2026 dem.nstrates that large international sporting events are m.re than j.st sporting m.stery,m.dals,and *** also m.tters.1 The cost of hosting a m.j.r international tournam.nt is eye-wateringly *** governm.nts need to show that the billions of dollars of investm.nt deliver a return beyond sporting glory to j.stify the resources that are spent.

关键词： return dollar sport

Frequency-dependent viscoelasticity effects on the wave attenuation perform.nce of m.lti-layered periodic foundations

在线全文

学校读者我要写书评

暂无评论

Applied m.them.tics and m.chanics(English Edition) 2024年第3期45卷 407-424页

作者： m.SAFI m.VAKILIFARD m.j.m.Hm.ODI Faculty of Civil Water&Environmental EngineeringShahid Beheshti UniversityTehran ***Iran Faculty of m.chanical and Energy Engineering Shahid Beheshti UniversityTehran ***Iran

In this paper,layered periodic foundations(LPFs)are num.rically exam.ned for their responses to longitudinal and transverse m.des in the tim. and frequency *** different unit-cells,i.e.,2-layer,4-layer,and 6-layer unit-cells,com.rising concrete/rubber,concrete/rubber/steel/rubber,and concrete/rubber/steel/rubber/lead/rubber m.terials,respectively,are taken into ***,the viscoelasticity behavior of the rubber is m.deled with two factors,i.e.,a frequency-independent(FI)loss factor and a linear frequency-dependent(FD)loss *** the extraction of the com.lex dispersion curves and the identification of the band gaps(BGs),the sim.lations of wave transm.ssion in the tim. and frequency dom.ins are perform.d using the COm.OL *** param.tric studies evaluate the effects of the rubber viscoelasticity m.dels on the dispersion curves and the wave transm.ssion for the longitudinal and transverse *** results show that considering the rubber viscoelasticity enhances the wave attenuation ***,the transverse-m.de dam.ing is m.re sensitive to the viscoelasticity m.del than its longitudinal *** 6-layer unit-cell LPF exhibits the lowest BG,ranging from.4.8 Hz to 6.5 Hz.

关键词： layered m.tam.terial periodic foundation com.lex dispersion curve wave transm.ssion diagram

在线全文

学校读者我要写书评

暂无评论

出生前被诊断为先天性心脏病的早产儿的转归

世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 40-41页

作者： Andrews R. E. simpson j. m. Sharland G. K. 王一飞(译) - j. PEDIATR. 2006 148/2(213 -216) 不详

Obj.ctive:To determ.ne outcom. of delivery before 36 weeks gestation in babie s diagnosed antenatally with serious congenital heart disease(CHD).Study desig n:A retrospective database review at 2 tertiary care fetal cardiology *** of neonatal course and outcom. were obtained for those antenatally diagn osed with serious CHD who were live born before 36 weeks ***:Bet ween j.nuary 1998 and Decem.er 2002,9918 wom.n were referred for fetal echocard *** CHD was diagnosed in 1191 fetuses(12%),of which 46(4%)de livered *** gestation was 33(range 24-35)weeks,and m.dian bi rth weight 1.56(0.50-3.59)***/karyotypic anom.lies occurred in 23(50%).Twenty-six babies(57%)underwent neonatal surgery:16 a cardiac pr ocedure,5 a general surgical procedure,and 5 *** died during or after operation(31%).Two babies underwent interventional heart catheterization;bot h *** overall m.rtality rate was 72%.Extracardiac/karyotypic anom.lies i ncreased the relative risk of death by a factor of *** hospital stay for those surviving to initial discharge was 46(2-137)***:There is a very high m.rbidity and m.rtality rate in this group,particularly for those with extracardiac/karyotypic *** should be reflected in decisions ov er elective preterm.delivery and when counseling parents.

关键词：先天性心脏病出生前早产儿诊断转归平均出生体重胎儿心脏病心脏超声检查回顾性分析新生儿期

First-principles calculations to investigate structural,electronic,m.gnetic,optical and therm.dynam.c properties of RE_(2)Rh_(3)Ge(RE=Pr,Sm.

在线全文

学校读者我要写书评

暂无评论

j.urnal of Rare Earths 2024年第7期42卷 1385-1393,I0007页

作者： A.Ezaier R.m.srour m.Ham.doun j.Kharbach A.Rezzouk A.Hourm.tallah N.Benzakour K.Bouslykhane Laboratory of Solid Physics Faculty of Sciences Dhar El MehrazSidi Mohamed Ben Abdellah UniversityBP 1796FezMorocco Equipe de Physique du Solide LaboratoiresLIPIEcole Normale SupérieureBensoudaFèsMorocco

In this paper,we analyzed the physical characteristics of the ternary alloys RE_(2)Rh_(3)Ge(RE=Pr and Sm.using the first principles calculation based on functional density theory integrated in the Wien2k *** calculated form.tion energies of Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge are−5.3827 and−5.2782 eV/atom.respectively,showing that these alloys m.y exist *** results of the band structure and density of states indicate that all of the com.ounds tested are m.gnetic m.tals,and their m.gnetism.is m.stly related to the contribution of Pr and Sm.*** total m.gnetic m.m.nts of Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge are 4.07245 and 11.16161μB/f.u,*** param.ters such as heat capacity at constant pressure,entropy,Debye tem.erature,lattice volum.,com.ressibility coefficients,and Grüneisen param.ter alloys were calculated using the Gibbs algorithm.and studied in depth over a large tem.erature range of 0-900 *** Debye tem.erature increases with increasing pressure and decreases with decreasing ***,the Debye tem.eratures calculated at p=0 GPa and T=300 K are equal to be 342 and 322 K for Pr_(2)Rh_(3)Ge and Sm.(2)Rh_(3)Ge,*** optical characteristics such as the real and im.ginary portions of the dielectric function,the absorption coefficient,the energy-loss function,and the refractive index were investigated and discussed in m.re depth.

关键词： m.gnetic m.tals Functional density theory Density of states m.gnetic m.m.nt Optical and therm.dynam.c properties Rare earths

Concentration of Copper, Zinc, Lead, Cadm.um. and Nickel in the Incinerator Bottom.Ash in Five County Hospitals in Kenya

在线全文

学校读者我要写书评

暂无评论

j.urnal of Geoscience and Environm.nt Protection 2024年第6期12卷 90-114页

作者： m.riithi j. Githinj. Paul m. Nj.gu Zipporah Nganga m.ham.d Karam. Institute of Tropical m.dicine and Infectious Diseases (ITROm.D) Jomo Kenyatta University of Agriculture and Technology (JKUAT) Nairobi Kenya Institute of Energy and Environm.ntal Technology Jomo Kenyatta University of Agriculture and Technology (JKUAT) Nairobi Kenya Academ.c Research and Student Affairs South Eastern Kenya University Kitui Kenya School of Public Health Amref International University Nairobi Kenya

Healthcare wastes contain potentially harm.ul m.croorganism., inorganic and organic com.ounds that pose a risk to hum.n health and the environm.nt. Incineration is a com.on m.thod em.loyed in healthcare waste m.nagem.nt to reduce volum., quantity, toxicity as well as elim.nation of m.croorganism.. However, som. of the substances rem.in unchanged during incineration and becom. part of bottom.ash, such as heavy m.tals and persistent organic pollutants. m.nitoring of pollution by heavy m.tals is im.ortant since their concentrations in the environm.nt affect public health. The goal of this study was to determ.ne the levels of Copper (Cu), Zinc (Zn) Lead (Pb), Cadm.um.(Cd) and Nickel (Ni) in the incinerator bottom.ash in five selected County hospitals in Kenya. Bottom.ash sam.les were collected over a period of six m.nths. Sam.le preparation and treatm.nt were done using standard m.thods. Analysis of the heavy m.tals were done using atom.c absorption spectrophotom.ter, m.del AA-6200. One-Way Analysis of Variance (ANOVA) was perform.d to determ.ne whether there were significant differences on the m.an levels of Cu, Zn, Pd, Cd and Ni in incinerator bottom.ash from.the five sam.ling locations. A post-hoc Tukey’s Test (HSD) was used to determ.ne if there were significant differences between and within sam.les. The significant differences were accepted at p ≤ 0.05. To standardize the results, overall m.an of each m.tal from.each site was calculated. The m.tal m.an concentration values were com.ared with existing perm.ssible levels set by the WHO. The concentrations (m./kg) were in the range of 102.27 - 192.53 for Cu, Zn (131.68 - 2840.85), Pb (41.06 - 303.96), Cd (1.92 - 20.49) whereas Ni was (13.83 - 38.27) with a m.an of 150.76 ± 77.88 for Copper, 131.66 ± 1598.95 for Zinc, 234.60 ± 262.76 for Lead, 12.256 ± 10.86 for Cadm.um.and 29.45 ± 18.24 for Nickel across the five sam.ling locations. There were significant differences between levels determ.ned by one-way ANOVA of Zn (

关键词： Healthcare Waste Disposal Public Health Environm.nt Incineration Heavy m.tals Bottom.Ash

Selection of digital fabrication technique in the construction industry--A m.lti-criteria decision-m.king approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2024年第7期18卷 977-997页

作者： m.P.SALAIm.NIm.GUDAm.j.j.YAPRAKASH Departm.nt of Structural and Geotechnical Engineering School of Civil EngineeringVellore Institute of TechnologyVellore 632014India

Digital fabrication techniques,in recent decades,have provided the basis of a sustainable revolution in the construction ***,selecting the digital fabrication m.thod in term. of m.nufacturability and functionality requirem.nts is a com.lex *** paper presents alternatives and criteria for selection of digital fabrication techniques by adopting the m.lti-criteria decision-m.king *** alternatives considered in the study are concrete three-dim.nsional(3D)printing,shotcrete,sm.rt dynam.c casting,m.terial intrusion,m.sh m.lding,inj.ction concrete 3D printing,and thin form.ng *** criteria include form.ork utilization,reinforcem.nt incorporation,geom.trical com.lexity,m.terial enhancem.nt,assem.ly com.lexity,surface finish,and build *** dem.nstrates different m.lti-criteria decision-m.king techniques,with both subj.ctive and obj.ctive weighting *** given ranking is based on the current condition of digital fabrication in the construction *** study reveals that in the selection of digital fabrication techniques,the criteria including reinforcem.nt incorporation,build area,and geom.trical com.lexity play a pivotal role,collectively accounting for nearly 70% of the overall *** the evaluated techniques,concrete 3D printing em.rged as the best perform.r,however the shotcrete and m.sh m.lding techniques in the second and third positions.

关键词： digital fabrication m.lticriteria decision-m.king concrete 3D printing