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Avian Research 2017年第4期8卷 202-209页

作者： Elizabeth Louise Sheldon simon Charles Griffith Department of Biological Sciences Macquarie UniversitySydneyNSW 2109Australia

Background: The House Sparrow(Passer domesticus) has undergone dramatic population declines in many parts of *** has been widely hypothesised that a lack of cavity nest sites has contributed to this *** the idea of the House Sparrow being nest site limited is somewhat incompatible with the long history of nest site plasticity in the ***: The nest-site selection in a population of non-native House Sparrows introduced to Australia from Europe just over 150 years ago was *** prevalence of non-cavity nesting was quantified,and nest-site selection in terms of landscape and nesting structure were ***: Flexible nesting behaviors were reported over a range of different landscapes and a surprisingly high rate of nesting in vegetation(43%) was *** nests found in vegetation were not in cavities,but were woven into the foliage and supported by branches and ***: The high rate of vegetation nesting indicates that in this introduced population,the House Sparrow is unlikely to be constrained by cavity-nest site *** high degree of nest site plasticity in the Australian population may suggest that European House Sparrows have the potential to shift away from their proclivity for cavity *** work in Europe should examine the incidence of non-cavity nesting in House Sparrows more closely,and perhaps reconsider the idea that House Sparrows are nest-site constrained.

关键词： Passer domesticus Cavity nests House Sparrow decline Nesting plasticity

Campylobacterjejuni in Musca domestica： An examination of survival and transmission potential in light of the innate immune responses of the house flies

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Insect Science 2017年第4期24卷 584-598页

作者： Carson Gill simon Bahrndorff Carl Lowenberger Department of Biological Sciences Simon Fraser University 8888 University Drive Burnaby BC Canada National Food Institute Technical University of Denmark 2800 Kongens Lyngby Denmark

The house fly, Musca domestica, has been implicated as a vector of Campy- lobacter spp., a major cause of human disease. Little is known whether house flies serve as biological amplifying hosts or mechanical vectors for Campylobacterjejuni. We in- vestigated the period after C. jejuni had been ingested by house flies in which viable C. jejuni colonies could be isolated from whole bodies, the vomitus and the excreta of adult M. domestica and evaluated the activation of innate immune responses of house flies to ingested C. jejuni over time. C. jejuni could be cultured from infected houseflies soon after ingestion but no countable C. jejuni colonies were observed 〉 24 h postingestion. We detected viable C. jejuni in house fly vomitus and excreta up to 4 h after ingestion, but no viable bacteria were detected 〉 8 h. Suppression subtractive hybridization identi- fied pathogen-induced gene expression in the intestinal tracts of adult house flies 4-24 h after ingesting C. jejuni. We measured the expression of immune regulatory （thor, JNK, and spheroide） and effector （cecropin, diptericin, attacin, defensing, and lysozyme） genes in C. jejuni-infected and -uninfected house flies using quantitative real time PCR. Some house fly factor, or combination of factors, eliminates C. jejuni within 24 h postingestion. Because C. jejuni is not amplified within the body of the housefly, this insect likely serves as a mechanical vector rather than as a true biological, amplifying vector for C. jejuni, and adds to our understanding of insect pathogen interactions.

关键词： antimicrobial peptides Campylobacter spp. Campylobacteriosis house fly innate immunity Musca domestica suppression subtractive hybridization (SSH) vector

Analysis of pneumatic atomizer spray profiles

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Particuology 2016年第6期14卷 80-85页

作者： Walter Schafer simon Rosenkranz Felix Brinckmann Cameron Tropea AOM-Systems GmbH Flughafenstrasse 15 64347 Griesheim Germany LacTec GmbH Otto-Hahn-Strasse 6-8 63110 Rodgau Germany Institute of Fluid Mechanics and Aerodynamics Technische Universitat Darmstadt Alarich-Weiss-Strasse 10 64287 Darmstadt Germany Graduate School of Computational Engineering Technische Universitat Darmstadt Dolivostrasse 15 64287 Darmstadt Germany

Our objective is to analyze the atomization processes of a pneumatic atomizer by measuring the size and velocity distributions of droplets in a liquid paint spray. The droplet size and velocity distributions have been determined at different axial positions in the spray; a mathematical description of how these quan- tities vary throughout the spray is then proposed. Additionally, the relative number density of droplets and the relative local mass flux are estimated.

关键词： Pneumatic atomizer Spray Measurement Droplet size profile Droplet velocity profile Time-shift

Ischemia and reperfusion injury of the spinal cord:experimental strategies to examine postischemic paraplegia

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Neural Regeneration Research 2016年第3期11卷 414-415页

作者： Florian simon Alexander Oberhuber Clinic for Vascular-and Endovascular Surgery Heinrich-Heine-University

Thoracoabdominal aortic replacement,necessary in case of injuries,aneurysms and dissections,shows a high complication rate as a consequence of the perioperative ischemia/reperfusion-sequence（I/R）.Clamping above and below the lesion leads to the spinal cord suffering from *** times of less than 30 minutes show only a small risk of neurological deficit,

关键词： deficit minutes neurological replacement injuries suffering consequence longer thoracic subsequent

simon Labbé's work on iron and copper homeostasis

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World Journal of Biological Chemistry 2010年第5期1卷 196-200页

作者： simon Labbé Department of Biochemistry Faculty of MedicineUniversitéde Sherbrooke300112e Avenue NordSherbrooke J1H 5N4Canada

Iron and copper have a wealth of functions in biological systems,which makes them essential micronutrients for all living *** in iron and copper homeostasis are directly responsible for diseases,and have been linked to impaired development,metabolic syndromes and fungal ***,it is crucial to gain a comprehensive understanding of the molecular bases of iron-and copper-dependent proteins in living *** Labbémaintains parallel programs on iron and copper homeostasis using the fission yeast Schizosaccharomyces pombe(***) as a model *** study of fission yeast transition-metal metabolism has been successful,not only in discerning the genes and pathways functioning in ***,but also the genes and pathways that are active in mammalian systems and for other fungi.

关键词： Iron and copper transport systems Metalloregulatory sensors Iron-and copper-responsivegenes Metal trafficking pathways Metalloenzymes Fungi as model systems

Management of intestinal failure in inflammatory bowel disease:Small intestinal transplantation or home parenteral nutrition?

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World Journal of Gastroenterology 2014年第12期20卷 3153-3163页

作者： Elizabeth Harrison Philip Allan Amrutha Ramu Anil Vaidya simon Travis simon Lal Intestinal Failure Unit Salford Royal NHS Foundation Trust Translational Gastroenterology Unit Oxford University Hospitals NHS Trust Transplant Centre Oxford University Hospitals NHS Trust

Inflammatory bowel disease and Crohn’s disease in particular, is a common cause of intestinal failure. Current therapeutic options include home parenteral nutrition and intestinal transplantation. For most patients, home intravenous therapy including parenteral nutrition, with a good probability of long-term survival, is the favoured choice. However, in selected patients, with specific features that may shorten survival or complicate home parenteral nutrition, intestinal transplantation presents a viable alternative. We present survival, complications, quality of life and economic considerations that currently influence individualised decision-making between home parenteral nutrition and intestinal transplantation.

关键词： Inflammatory bowel disease, Crohn’ s disease, Intestinal failure, Intestinal transplantation, Home parenteral nutrition, Survival, Complications, Quality of life

Natural regeneration in logging gaps of different sizes in Subri River Forest Reserve(Ghana)

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Journal of Forestry Research 2022年第4期33卷 1157-1174页

作者： Maame Esi Hammond Radek Pokorný simon Abugre Augustine Gyedu Department of Silviculture Faculty of Forestry and Wood TechnologyMendel University in BrnoZemědělská361300 BrnoCzech Republic Department of Forest Science School of Natural ResourcesUniversity of Energy and Natural ResourcesP.O.Box 214SunyaniGhana Forest Services Division(FSD) P.M.BKumasiGhana

Subri River Forest Reserve(SR)is the most extensive forest area in Ghana with an accompanying rich floral *** the years,logging from both legally prescribed and illegal operations remain the predominant forest disturbance in *** creation following logging is crucial in determining tree species composition and ***,the study evaluated the composition and diversity of naturally regenerated tree species in logging gaps of different sizes and,again examined the roles of these tree species in fulfilling the economic and ecological agenda of sustainable forest management after logging in *** gaps were randomly selected:4 each were grouped into small size(≤200 m^(2)),medium size(201–300 m^(2)),and large size(≥300 m^(2)).Data were gathered from 1 m^(2) circular area at gap centres and repeatedly inside 1 m width strip along 20 m individual N-S-E-W *** diversity differed significantly between gap *** diversity indices were measured in large size *** sizes shared similar *** were significant differences among various height groupings of tree species across all three gap *** preferred medium to large size gaps,while shadetolerant tree species preferred small size gaps for their *** and Lower Risk Near Threatened tree species under Conservation Status and,Premium and Commercial tree species under Utilisation Status preferred small size gaps for their proliferation and ***,we recommend the single tree-based selective logging for ensuring creations of small to medium size(200–300 m^(2))gaps through adjustments to the logging permit process,revision of Allocation Quota Permit,strict adherence to the 40-year polycyclic selection system,along with more dedicated enforcement and *** along these protocols would tremendously facilitate natural regeneration of different suites of timber species resulting in the improvement of the overall biodiversity conservat

关键词： Conservation status Gap size Diversity Logging Natural regeneration Subri River Forest Reserve Tree species Utilisation status

Evolving management of metaplasia and dysplasia in Barrett's epithelium

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World Journal of Gastroenterology 2016年第47期22卷 10316-10324页

作者： Richard PT Evans Moustafa Mabrouk Mourad simon G Fisher simon R Bramhall Department of Surgery the Wye Valley NHS Trust

Oesophageal cancer affects more than 450000 people worldwide and despite continued medical advancements the incidence of oesophageal cancer is increasing. Oesophageal cancer has a 5 year survival of 15%-25% and now globally attempts are made to more aggressively diagnose and treat Barrett's oesophagus the known precursor to invasive disease. Currently diagnosis the of Barrett's oesophagus is predominantly made after endoscopic visualisation and histopathological confirmation. Minimally invasive techniques are being developed to improve the viability of screening programs. The management of Barrett's oesophagus can vary greatly dependent on the presence and severity of dysplasia. There is no consensus between the major international medical societies to determine and agreed surveillance and intervention pathway. In this review we analysed the current literature to demonstrate the evolving management of metaplasia and dysplasia in Barrett's epithelium.

关键词： Barrett’s Oesophagus Dysplasia Metaplasia Oesophageal cancer

Iris microhaemangioma: a management strategy

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International Journal of Ophthalmology(English edition) 2013年第2期6卷 246-250页

作者： Aruna Dharmasena simon Wallis Department of Ophthalmology Royal Bolton Hospital Foundation Trust

AIM: To analyse previous literature and to formulate a management strategy for iris microhaemangiomas (IMH).METHODS:Areview of the literature in English language articles on ***: Thirty five English language articles fulfilled the criteria for inclusion to the study and based on the contents on these articles a management strategy was formulated. Age at presentation ranged from 42 to 80 years with no sex or racial predisposition. Most patients with IMH have no systemic disease but a higher incidence had been reported in patients with diabetes mellitus, myotonic dystrophy, chronic obstructive pulmonary disease (COPD) and several other systemic and ophthalmic co-morbidities. Most patients remained asymptomatic until they experienced a sudden blurring of vision due to a hyphaema. Some patients only develop a self-limiting single episode of hyphaema and therefore the laser or surgical photocoagulation of iris should be reserved for the cases complicated with recurrent hyphaema. In some patients, several laser photoco-agulation sessions may be needed and the recurrent iris vascular tufts may require more aggressive treatment. Iris fluorescein angiography (IFA) is useful in identifying the true extent of the disease and helps to improve the precision of the laser treatment. Surgical excision (iridectomy) should only be considered in patients who fail to respond to repeated laser treatment. In some cases IMHs has been initially misdiagnosed as amaurosis fugax, iritis and Posner-Schlossman ***: Owing to its scarcity, there is no good quality scientific evidence to support the management of IMH. The authors discuss the various treatment options and present a management strategy based on the previous literature for the management for this rare condition and its complications.

关键词： iris microhaemangioma iris vascular tufts capillary haemangioma of iris Cobb's tufts Argon laser photocoagulation

Flow Field and Performance of Cross Flow Fans——Experimental and Theoretical Investigations

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Journal of Thermal Science 2003年第3期12卷 234-238页

作者： Martin Gabi simon Dornstetter Toni Klemm Institute of Fluid Machinery University of Karlsruhe (TH) D-76128 Karlsruhe GermanyRobert Bosch GmbH D-71701 Schwieberdingen GermanyInstitute of Fluid Machinery University of Karlsruhe (TH) D-76128 Karlsruhe Germany

Due to the construction and the operating principle the prediction of performance of Cross Flow Fans (CFF) is difficult and the knowledge about the internal flow regime is limited. To investigate the impact of geometrical parameters on the performance of CFF, experimental investigations, using Particle Imaging Velocimetry (PIV), and CFD calculations were carried out. Some results of PIV measurements and CFD calculations are presented, which give an impression of the internal flow and confirm the numerical calculations.

关键词： fans cross-flow fans computational fluid dynamics particle imaging velocimetry