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Dietary Supplementation of β-Carotene Reveals miRNAs Involved in the Regulation of Carotenoid Metabolism in Crassostrea gigas

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Journal of Ocean University of China 2024年第4期23卷 1045-1053页

作者： SUN Dongfang WAN Sai YU Hong kong Lingfeng LI Qi Key Laboratory of Mariculture Ministry of EducationOcean University of ChinaQingdao 266003China Laboratory for Marine Fisheries Science and Food Production Processes Laoshan LaboratoryQingdao 266237China

Carotenoids play crucial physiological roles in animals.A comprehensive investigation into the mechanism of carotenoid metabolism in oysters will establish a theoretical foundation for further development of its carotenoid-rich ***,the information on the function of miRNA in β-carotene metabolism in oysters is *** elucidate the mechanisms underlying miRNA regulation of carotenoid metabolism in oysters,we compared the expressions of miRNA in digestive gland tissues of Pacific oyster(Crassostrea gigas)fed with aβ-carotene supplemented diet and a normal diet,respectively.A total of 690 candidate miRNAs in the Pacific oyster digestive gland tissues were identified,including 590 known miRNAs and 111 unknown *** differentially expressed miRNAs were obtained in the carotenoid-fed and normal groups,associated to 137 differentially expressed target ***,the GO enrichment analysis revealed that the differentially expressed target genes were mainly involved in transmembrane transport *** enrichment showed that the differentially expressed target genes were involved in ABC *** of the mRNA-miRNA network revealed that novel0025 played a central role in carotenoid metabolism,and it was negatively correlated with the expression of 46 *** addition,down-regulated expression of novel0025 upregulated the expression of the lipoprotein gene LOC105342186,suggesting a potential regulatory role in carotenoid *** results provide useful information for elucidating the miRNA regulation mechanism during carotenoids metabolism in the Pacific oyster.

关键词： Crassostrea gigas β-carotene microRNA carotenoid metabolism

Residual subsidence time series model in mountain area caused by underground mining based on GNSS online monitoring

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International Journal of Coal Science & Technology 2024年第2期11卷 173-186页

作者： Xugang Lian Lifan Shi Weiyu kong Yu Han Haodi Fan School of Mining Engineering Taiyuan University of TechnologyTaiyuanChina

The residual subsidence caused by underground mining in mountain area has a long subsidence duration time and great potential harm,which seriously threatens the safety of people's production and life in the mining ***,it is necessary to use appropriate monitoring methods and mathematical models to effectively monitor and predict the residual subsidence caused by underground *** with traditional level survey and InSAR(Interferometric Synthetic Aperture Radar)technology,GNSS(Global Navigation Satellite System)online monitoring technology has the advantages of long-term monitoring,high precision and more flexible monitoring *** empirical equation method of residual subsidence in mining subsidence is effectively combined with the rock creep equation,which can not only describe the residual subsidence process from the mechanism,but also predict the residual ***,based on GNSS online monitoring technology,combined with the mining subsidence model of mountain area and adding the correlation coefficient of the compaction degree of caving broken rock and the Kelvin model of rock mechanics,this paper constructs the residual subsidence time series model of arbitrary point on the ground in mountain *** the example,the predicted results of the model in the inversion parameter phase and the dynamic prediction phase are compared with the measured data *** results show that the model can carry out effective numerical calculation according to the GNSS monitoring data of any point on the ground,and the model prediction effect is good,which provides a new method for the prediction of residual subsidence in mountain mining.

关键词： Underground mining in mountain area Residual subsidence GNSS online monitoring Mathematical model Subsidence prediction

Bridging molecular photosensitizer and catalyst on carbon nanotubes toward enhanced selectivity and durability for CO_(2)photoreduction

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Journal of Environmental Sciences 2024年第6期140卷 157-164页

作者： Xiaofeng Cui Xueting Wang Lijun Zhao Jixin Wang Tingting kong Yujie Xiong Anhui Engineering Research Center of Carbon Neutrality The Key Laboratory of Functional Molecular SolidsMinistry of EducationAnhui Laboratory of Molecular-Based MaterialsCollege of Chemistry and Materials ScienceAnhui Normal UniversityWuhu 241002China School of Chemistry and Chemical Engineering Anqing Normal UniversityAnqing 246011China School of Chemistry and Materials Science University of Science and Technology of ChinaHefei 230026China

Homogenous molecular photocatalysts for CO_(2)reduction,especially metal complex-based photosensitizer-catalyst assemblages,have been attracting extensive research interests due to their efficiency and ***,their low durability and recyclability limit practical *** this work,we immobilized the catalysts of metal terpyridyl complexes and the photosensitizer of[Ru(bpy)3]Cl2onto the surface of carbon nanotubes through covalent bonds and electrostatic interactions,respectively,transforming the homogeneous system into a heterogeneous *** characterizations prove that these metal complexes are well dispersed on CNTs with a high loading(ca.12 wt.%).Photocatalytic measurements reveal that catalytic activity is remarkably enhanced when the molecular catalysts are anchored,which is three times higher than that of homogeneous molecular ***,when the photosensitizer of[Ru(bpy)3]Cl2is immobilized,the side reaction of hydrogen evolution is completely suppressed and the selectivity for CO production reaches 100%,with its durability also significantly *** work provides an effective pathway for constructing heterogeneous photocatalysts based on rational assembly of efficient molecular photosensitizers and catalysts.

关键词： durability selectivity catalyst

Lipidomic remodeling during mammalian preimplantation embryonic development

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Life Metabolism 2024年第2期3卷 3-5页

作者： Qingran kong Shaorong Gao Zhejiang Provincial Key Laboratory of Medical Genetics Key Laboratory of Laboratory MedicineMinistry of EducationSchool of Laboratory Medicine and Life SciencesWenzhou Medical UniversityWenzhouZhejiang 325035China Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital Shanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China

The dynamic changes in lipids during early embryonic development in mammals have not yet been comprehensively investi*** a recent paper published in Nature Cell Biology,Zhang et *** the dynamic lipid landscapes during preimplantation embryonic development in mice and *** highlight the crucial role of lipid unsaturation in regulating embryogenesis.

关键词： Lipid al. lipids

Initial precursor reaction mechanism of CVD-HfC coating based on density functional theory

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Chinese Journal of Aeronautics 2024年第7期37卷 511-521页

作者： Yunzhou LIN Yulei ZHANG Yanqin FU Jian ZHANG Jing’an kong Ruicong CHEN State Key Laboratory of Solidification Processing Carbon/Carbon Composites Research CenterNorthwestern Polytechnical UniversityXi’an 710072China Henan Key Laboratory of High Performance Carbon Fiber Reinforced Composites Carbon Matrix Composites Research InstituteHenan Academy of SciencesZhengzhou 450046China

Recently,the preparation of ultra-high temperature HfC ceramic coating has gained significant attention,particularly through the application of the HfCl_(4)-CH_(4)-H_(2)-Ar system via Chemical Vapor Deposition(CVD),which has been found widely applied to C/C ***,an analysis of the reactions that occur in the initial stage of the CVD-HfC coating process is presented using Density Functional Theory(DFT)and Transition State Theory(TST)at the B3LYP/Lanl2DZ *** results reveal that HfCl4 can only cleave to produce hypochlorite,which will further react with methyl to synthesize intermediates to form *** to the analysis of the energy barrier and reaction constant,HfCl preferentially reacts with methyl groups to form complex adsorptive intermediates at 1573 *** a C—Hf bond production energy of 212.8 kcal/mol(1 kcal=4.18 kJ),the reaction rate constant of HfCl+CH is calculated to be 2.15×10^(-18) cm^(3)/s at 1573 ***,both the simulation and experimental results exhibit that the upward trend of reaction rate constants with temperature is also consistent with the deposition rate,indicating that the growth curve of the reaction rate constants tends to flatten *** proposed reaction model of the precursor’s decomposition and reconstruction during deposition process has significant implication for the process guidance.

关键词： Carbon composite HfC coating Chemical vapor deposition Density functional theory Precursor reaction mechanism

Recent Developments of Photodeformable Polymers:From Materials to Applications

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Research 2024年第2期2023卷 729-752页

作者： Shuting kong Hailan Wang Eethamukkala Ubba Yuxin Xiao Tao Yu Wei Huang Frontiers Science Center for Flexible Electronics(FSCFE) Shaanxi Institute of Flexible Electronics(SIFE)Northwestern Polytechnical University127 West Youyi RoadXian 710072China OMC Research Laboratory.Department of Chemistry School of Advanced SciencesVITVelloreTamilnaduIndia Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Nanjing Tech University(NanjingTech)30 South Puzhu RoadNanjing 211816China State Key Laboratory of Organic Electronics and Information Displays&Institute of Advanced Materials(IAM) Nanjing University of Posts and Telecommunications9 Wenyuan RoadNanjing 210023China

Photodeformable polymer materials have a far influence in the fields of flexibility and *** stimulation energy is converted into mechanical energy through molecular *** kinds of photodeformable polymer materials,liquid crystalline polymer(LCP)photodeformable materials have been a hot topic in recent *** such as azobenzene,a-cyanostilbene,and 9,10-dithiopheneanthracene have been widely used in LCP,which are helpful for designing functional molecules to increase the penetration depth of light to change physical *** to the various applications of photodeformable polymer materials,there are many excellent reports in intelligent *** this review,we have systematized LCP containing azobenzene into 3 categories depending on the degree of crosslinking liquid crystalline elastomers,liquid crystalline networks,and linear *** structural,typical polymer materials and their applications are *** issues faced and future directions to be developed for photodeformable polymer materials are also summarized.

关键词： properties. field. crystalline

A vector sum analysis method for stability evolution of expansive soil slope considering shear zone damage softening

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3746-3759页

作者： Junbiao Yan Lingwei kong Cheng Chen Mingwei Guo State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China

Slope stability analysis is a classical mechanical problem in geotechnical engineering and engineering *** is of great significance to study the stability evolution of expansive soil slopes for engineering construction in expansive soil *** of the existing studies evaluate the slope stability by analyzing the limit equilibrium state of the slope,and the analysis method for the stability evolution considering the damage softening of the shear zone is *** this study,the large deformation shear mechanical behavior of expansive soil was investigated by ring shear *** damage softening characteristic of expansive soil in the shear zone was analyzed,and a shear damage model reflecting the damage softening behavior of expansive soil was derived based on the damage ***,by skillfully combining the vector sum method and the shear damage model,an analysis method for the stability evolution of the expansive soil slope considering the shear zone damage softening was *** results show that the shear zone subjected to large displacement shear deformation exhibits an obvious damage softening *** damage variable equation based on the logistic function can be well used to describe the shear damage characteristics of expansive soil,and the proposed shear damage model is in good agreement with the ring shear test *** vector sum method considering the damage softening behavior of the shear zone can be well applied to analyze the stability evolution characteristics of the expansive soil *** stability factor of the expansive soil slope decreases with the increase of shear displacement,showing an obvious progressive failure behavior.

关键词： Expansive soil slope Stability analysis Ring shear test Vector sum method Damage model Strain softening

强直性脊柱炎患者运动指导方案的最佳证据总结

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中华护理杂志 2023年第7期58卷 864-870页

作者：马喜宁白艳娟孔思铭黄蓉张静姚辉宁夏回族自治区人民医院风湿免疫科银川市750001

目的总结强直性脊柱炎患者运动指导方案的最佳证据,为对强直性脊柱炎患者实施运动指导提供依据。方法计算机系统检索UpToDate、BMJ最佳临床实践、OVID、CINAHL、Cochrane Library、Embase、PubMed、Scopus、中国知网、万方数据库、维普... 详细信息

目的总结强直性脊柱炎患者运动指导方案的最佳证据,为对强直性脊柱炎患者实施运动指导提供依据。方法计算机系统检索UpToDate、BMJ最佳临床实践、OVID、CINAHL、Cochrane Library、Embase、PubMed、Scopus、中国知网、万方数据库、维普数据库、中国生物医学文献数据库、医脉通等指南网及专业协会网站和数据库中关于强直性脊柱炎患者运动方案的指南、系统评价、Meta分析、专家共识、证据总结、最佳临床实践等,检索时限为2012年1月1日—2022年1月1日,由2名护士独立对文献进行筛选、质量评价、提取最佳证据并分级,总结运动指导方案的最佳证据。结果共纳入文献16篇,包括指南1篇、系统评价6篇、Meta分析4篇、专家共识5篇,总结出运动指导方案的最佳证据包括运动前评估、运动适用范围、不同疾病阶段分期的运动类型、运动项目内容(项目、内容、运动强度、频率、周期)、监督方式、运动监测指标、运动风险评估、注意事项共8个方面,39条证据。结论该研究总结的强直性脊柱炎患者运动指导方案的最佳证据,规范了强直性脊柱炎患者康复运动的理论、实践,形成科学、规范、基于最佳证据的运动指导方案。

关键词：强直性脊柱炎自身免疫疾病运动最佳证据康复护理循证护理学

Underwater image clarifying based on human visual colour constancy using double-opponency

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CAAI Transactions on Intelligence Technology 2024年第3期9卷 632-648页

作者： Bin kong Jing Qian Pinhao Song Jing Yang Amir Hussain Institute of Intelligent Machines Chinese Academy of SciencesHefeiChina Peng Cheng Laboratory ShenzhenChina Anhui Key Laboratory of Biomimetic Sensing and Advanced Robot Technology HefeiChina University of Science and Technology of China HefeiChina Peking University Shenzhen Graduate School ShenzhenChina Edinburgh Napier University EdinburghScotland

Underwater images are often with biased colours and reduced contrast because of the absorption and scattering effects when light propagates in *** images with degradation cannot meet the needs of underwater *** main problem in classic underwater image restoration or enhancement methods is that they consume long calcu-lation time,and often,the colour or contrast of the result images is still *** of using the complicated physical model of underwater imaging degradation,we propose a new method to deal with underwater images by imitating the colour constancy mechanism of human vision using ***,the original image is converted to the LMS *** the signals are linearly combined,and Gaussian convolutions are per-formed to imitate the function of receptive fields(RFs).Next,two RFs with different sizes work together to constitute the double-opponency ***,the underwater light is estimated to correct the colours in the *** contrast stretching on the luminance is *** show that the proposed method can obtain clarified underwater images with higher quality than before,and it spends significantly less time cost compared to other previously published typical methods.

关键词： computers computer vision image processing image reconstruction