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宏图:珠江三角洲景观动态解析

风景园林 2019年第9期26卷 23-30页

作者： [德]西格丽德·赫尔-兰格埃卡特·兰格陆熹(译) 英国谢菲尔德大学景观学院英国皇家风景园林学会

聚焦珠江三角洲地区的景观动态演变,重点介绍影响该区域在未来变化中的一些关键问题和驱动因素。三角洲的景观形成以自然动态和过程演替为特征,而土壤沉积是形成其景观格局的关键性因素。人类的活动极大程度地改变了珠江三角洲的景观格... 详细信息

聚焦珠江三角洲地区的景观动态演变,重点介绍影响该区域在未来变化中的一些关键问题和驱动因素。三角洲的景观形成以自然动态和过程演替为特征,而土壤沉积是形成其景观格局的关键性因素。人类的活动极大程度地改变了珠江三角洲的景观格局。数百年前,大规模的原生林被急剧砍伐,致使其遭受了严重的水土流失和泥沙沉积,直至20世纪末实施“植树造林”计划,毁林导致生态恶化的情形才有所缓解。在低洼的冲积平原,农业和水产养殖业则在很大程度上依赖于对堤防系统和地下水位的管理。珠江三角洲具有得天独厚的基塘农业系统,但伴随着高强度的城市化进程,其蚕桑生产逐渐萎缩,而高度集约化的现代水产养殖正在这些区域蔓延。近几十年来,珠三角都市群已拥有1.2亿居民。伴随着人口膨胀,采砂和疏浚常被用来满足日益增长的基建需求,水坝和水库的建设也大量减少了珠江所携带的泥沙沉积,这些因素都致使珠三角的沉积物呈负平衡的状态。与此同时,湿地资源也面临着巨大的考验,诸多问题如土壤侵蚀与采砂工程,进一步加大对滨海和河口湿地的负面影响。上述这些互相牵制且高度复杂的环境问题,亟须通过多尺度、跨学科协作的方法进行研究并寻求解决方法,进而为实现更加可持续的环境管理提供科学的依据。

关键词：风景园林景观动态景观变化的驱动因素沉积采砂水库城市化森林砍伐水产养殖湿地环境管理

国际糖尿病足工作组:糖尿病足溃疡周围动脉病变诊断、预后与管理指南——《国际糖尿病足工作组:糖尿病足防治国际指南(2019)》的一部分

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感染．炎症．修复 2019年第4期20卷 195-206页

作者： Robert J.Hinchliffe Rachael O.Forsythe Jan Apelqvist Ed J.Boyko Robert Fitridge Joon Pio Hong Konstantinos Katsanos Joseph L.Mills sigrid nikol Jim Reekers Maarit Venermo R.Eugene Zierler nicolaas C.Schaper 无许樟荣(译) 冉兴无(审校) Bristol Centre for Surgical Research University of BristolBristolUK British Heart Foundation/University of Edinburgh Centre for Cardiovascular Science University of EdinburghEdinburghScotlandUK Department of Endocrinology University Hospital of MalmoSweden Seattle Epidemiologic Research and Information Centre-Department of Veterans Affairs Puget Sound Health Care System and the University of Washington SeattleWashingtonUSA Vascular Surgery The University of AdelaideAdelaideSouth AustraliaAustralia Asan Medical Center University of Ulsan SeoulKorea Patras University Hospital School of Medicine RionPatrasGreece SALSA(Southern Arizona Limb Salvage Alliance) University of Arizona Health Sciences CenterTucsonArizonaUSA Asklepios Klinik *** HamburgGermany Department of Vascular Radiology Amsterdam Medical CentreThe Netherlands Helsinki University Hospital University of HelsinkiFinland Department of Surgery University of WashingtonSeattleWashingtonUSA Div.Endocrinology MUMC+CARIM and CAPHRI InstituteMaastrichtThe Netherlands International Working Group on the Diabetic Foot(IWGDF) 战略支援部队特色医学中心北京100101 四川大学华西医院四川成都610041

1999年以来,国际糖尿病足工作组(IWGDF)已经多次发表循证医学基础上的糖尿病足预防与管理指南。该指南是有关糖尿病足溃疡合并周围动脉病变(PAD)患者的诊断、预后和管理指南,更新了以前IWGDF指南的内容。高达50%的糖尿病足溃疡患者同时... 详细信息

1999年以来,国际糖尿病足工作组(IWGDF)已经多次发表循证医学基础上的糖尿病足预防与管理指南。该指南是有关糖尿病足溃疡合并周围动脉病变(PAD)患者的诊断、预后和管理指南,更新了以前IWGDF指南的内容。高达50%的糖尿病足溃疡患者同时患有PAD,这种病变使得患者截肢和心血管病变的风险明显增加。这类患者的诊断、预后和治疗明显地不同于那些没有PAD的糖尿病患者,但仅有很少的关于这类患者的高质量的研究强调了这点。我们遵循GRADE方法来提出临床问题并以至少包括患者-干预-比较-结局(PICO)形式说明重要结局,进行了系统的医学科学文献评价,写出推荐意见及其合理性。这类推荐是建立在系统文献评价的循证医学基础上的,没有证据时则在权衡利弊和患者选择、便宜性和干预的费用等因素后,采用专家的观点。这里我们发布更新的2019年糖尿病足溃疡合并PAD患者的有关PAD诊断、预后和管理的指南,以及一些需要未来特别关注的研究课题。

关键词：糖尿病足足溃疡指南周围动脉病变外科诊断预后血管病变

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可持续低温漂白技术

国际纺织导报 2017年第1期45卷 28-28,30-32页

作者： A.Mehlhorn S.Mobius A.Knoblauch M.Peukert 刘蒙稣(译) 程心怡(译) 罗艳(校) Zschimmer&Schwarz Mohsdorf公司德国不详

织物预处理在纺织品整理过程中起着关键作用,这不仅在于它可为高品质的最终产品提供基础,还在于其对环境的影响。纺织品的常规漂白是在高工艺温度条件下进行的,涉及到大量的水、废水及能源。为保护环境,通过采用Zschimmer & Schwarz Moh... 详细信息

织物预处理在纺织品整理过程中起着关键作用,这不仅在于它可为高品质的最终产品提供基础,还在于其对环境的影响。纺织品的常规漂白是在高工艺温度条件下进行的,涉及到大量的水、废水及能源。为保护环境,通过采用Zschimmer & Schwarz Mohsdorf公司开发的生态且经济的Cold White低温漂白技术,可实现对能源与资源的环保利用。

关键词：低温漂白 Cold White 可持续织物预处理

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音乐屋——奥尔堡创意中心

城市环境设计 2020年第4期126卷 174-185页

作者：沃尔夫·狄·普瑞克斯 Marcelo Bernardi Jesper Bork Bo Stjerne Hansen Roberta Jiraschek Daniel Krüger Carsten Laursen Martin Oberascher Florian Pfeifer Robert Pippan Marita Schnepper sigrid Svensson Eva Wolf Carola B?ker Moa Carlson Isak Foged Annina G?hwiler Patricia Gola Robin Heather Per Kruse Win Man Ruth Mandl Aline Müller Tenna Olsen Anke Pasolt Annemarie Pedersen Eva Ravnborg Carolin Schmitz-Remberg Tim Seidl Guro Sollid Michele Zanella Jan-Ruben Fischer Markus Pillhofer Markus Baumann Robin Heather Anja Sorger Bo Stjerne Thomsen Anna Wasserthal Philip Wilck Blaine Lepp Talya Kozminsky Hannes Walzl Morten Grau Jensen Stephanie neufeld Tyler Bornstein Laura Githa Julia G?rtner Jenny Draxlbauer Duccio Malagamba Martin Schubert

项目大事记/CHROnOLOGY竞赛（第一名）/Competition （1st Place）:2003一期规划设计/Layout Planning Ho M I:2003—2005项目延期/Postponement of the Project:2006—2007二期规划设计/Start of Layout Planning Ho M II:2008二期动工/Start of Construction Ho M II:2010二期竣工/Completion Ho M II:2014项目参数/PROJECT DATA建筑净面积/net Floor Area:17 637m2建筑毛面积/Gross Floor Area:20 257m2音乐厅/Concert Hall:1 298座/1 289 Seats

关键词：

Cell:新分子或可有效清除肝脏和血液中的脂肪

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现代生物医学进展 2017年第4期17卷 I0004-I0004页

作者： Brian Finan Christoffer Clemmensen Zhimeng Zhu Kerstin Stemmer Karine Gauthier Luisa M uuml ller Meri De Angelis Kristin Moreth Frauke neff Diego Perez-Tilve Katrin Fischer Dominik Lutter Miguel A. S aacute nchez-Garrido Peng Liu Jan Tuckermann Mohsen Malehmir Marc E. Healy Achim Weber Mathias Heikenwalder Martin Jastroch Maximilian Kleinert sigrid Jall Sara Brandt Fr eacute d eacute ric Flamant Karl-Werner Schramm Heike Biebermann Yvonne D ouml ring Christian Weber Kirk M. Habegger Michaela Keuper Vasily Gelfanov Fa Liu Josef K ouml hrle Jan Rozman Helmut Fuchs Valerie Gailus-Durner Martin Hrabě de Angelis Susanna M. Hofmann Bin Yang Matthias H. Tsch ouml p Richard DiMarchi Timo D. M uuml ller Institute for Diabetes and Obesity Helmholtz Diabetes Center at Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) 85764 Neuherberg Germany Department of Chemistry Indiana University Bloomington IN 47405 USA Institut de Génomique Fonctionnelle de Lyon Université de Lyon Centre National de la Recherche Scientifique (CNRS) Institut National de la Recherche Agronomique (INRA) École Normale Supérieure de Lyon 69364 Lyon France Molecular EXposomics Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) 85764 Neuherberg Germany German Mouse Clinic Institute of Experimental Genetics Helmholtz Zentrum München German Research Center for Environmental Health 85764 Neuherberg Germany Division of Endocrinology Department of Internal Medicine Metabolic Diseases Institute University of Cincinnati College of Medicine Cincinnati OH 45237 USA Institute of Comparative Molecular Endocrinology University of Ulm 89081 Ulm Germany Department of Pathology and Molecular Pathology University Zurich and University Hospital Zurich 8091 Zurich Switzerland Institute of Virology Technische Universität München 81675 Munich Germany Institute of Experimental Pediatric Endocrinology Charité-Universitätsmedizin Berlin Berlin 13353 Germany Department of Medicine Institute for Cardiovascular Prevention Ludwig-Maximilians-Universität München 80336 Munich Germany Comprehensive Diabetes Center and Department of Medicine-Endocrinology Diabetes & Metabolism University of Alabama at Birmingham Birmingham AL 35294 USA Institute for Diabetes and Regeneration Helmholtz Diabetes Center at Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) Neuherberg 85764 Germany Calibrium LLC Carmel IN 46032 USA Institute for Experimental Endocrinology Charité-Universitätsmedizin Berlin Berlin 13353 Germany German Center for Diabetes Research (DZD) 85764 Neuherberg Germany

肥胖和糖尿病持续上升代表着我们的社会所面临的一个重大的负担。脂肪肝和动脉粥样硬化是这些代谢疾病常见的后果，但是开发一种高效且又安全的能够逆转肥胖、胰岛素抵抗性、脂肪肝和动脉粥样硬化的药物仍然是全球头等的一项重大的科学... 详细信息

肥胖和糖尿病持续上升代表着我们的社会所面临的一个重大的负担。脂肪肝和动脉粥样硬化是这些代谢疾病常见的后果，但是开发一种高效且又安全的能够逆转肥胖、胰岛素抵抗性、脂肪肝和动脉粥样硬化的药物仍然是全球头等的一项重大的科学挑战。

关键词：脂肪肝 Cell 动脉粥样硬化血液肝脏清除分子代谢疾病

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宝马世界

城市环境设计 2020年第4期126卷 134-149页

作者：沃尔夫·狄·普瑞克斯 Paul Kath Tom Wiscombe Waltraut Hoheneder Mona Marbach Hans Aescht Beatrix Basting Guy Bebiè Chris Beccone Johannes Behrens Marcelo Bernardi Pawel Bodzak Verena Boyer Antja Bulthaup Claudia Buhmann Timo Carl Jan Chaldil Ing Tse Chen Tadeusz Chimiak Andrea Christmann Patrick Erhardt Stephan Exsternbrink Wolfgang Fiel Benedikt Frass Helmut Fr?tscher Volker Gessendorfer Andrea Graser Lukas Haller Markus Henning Armin Hess Jens Hoff Tamas Horvath Robert Huebser Astrid Jagersberger Marin Jurycz Gregor Kassl Areta Keller Markus Klausecker Tobias Klein Martin Konrad Quirin Krumbholz Caroline Kufferath Marion Lattenmayer Stefan Laub Wolfgang Leitgeb Andreas Mieling Karin Miesenberger Dennis Milam Elke Müller Henrike Münker Claudia nehammer Martin Oberascher Alexander Ott Stefan Pfefferle Florian Pfeifer Markus Pillhofer Ekkehard Rehfeld Goswin Rothenthal Wolfgang Ruthensteiner Jasmin Sauerbier Florian Schafschetzy Kristina Schinegger Karolin Schmidbaur Patrick Schneider Katharina Schneider Hubert Schoba Angus Schoenberger Andrea Sch?ning Anja Sorger Gernot Stangl Mark Steinmetz sigrid Steinwender Martina Tippelskirch Dionicio Valdez Pascal Vauclair Akvile Rimantaite Andreas Weissenbach Heribert Wolfmayer Irina Zahler 2007 Ari Marcopoulos Gerald Zugmann Hélène Binet Duccio Malagamba Marcus Buck Christian Richters Richard Walch

项目大事记/CHROnOLOGY竞赛（一等奖）/Competition（1st Prize）:2001规划设计起始时间/Start of Planning:11/2001施工起始时间/Start of Construction:08/2003投入使用/Opening:20/10/2007-21/10/2007项目参数/PROJECT DATA用地面积/Site Area:约25 000m2/Approx. 25 000m2建筑毛面积/Gross Floor Area:约73 000m2（除坡道）=100%/Approx.73 000m2（excluding ramps）=100%地上建筑毛面积/Gross Floor Area above ground:约28 500m2=40%/Approx.28 500m2=40%地下建筑毛面积/Gross Floor Area underground:约44 500m2=60%/Approx.44 500m2=60%

关键词：

Interaction of Diet/Lifestyle Intervention and TCF7L2 Genotype on Glycemic Control and Adiposity among Overweight or Obese Adults:Big Data from Seven Randomized Controlled Trials Worldwide

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Health Data Science 2021年第1期2021卷 174-183页

作者： Tao Huang Zhenhuang Zhuang Yoriko Heianza Dianjianyi Sun Wenjie Ma Wenxiu Wang Meng Gao Zhe Fang Emilio Ros Liana C.Del Gobbo Jordi Salas-Salvadó Miguel A.Martínez-González Jan Polak Markku Laakso Arne Astrup Dominique Langin Jorg Hager Gabby Hul Torben Hansen Oluf Pedersen Jean-Michel Oppert Wim H.M.Saris Peter Arner Montserrat Cofán Sujatha Rajaram Jaakko Tuomilehto Jaana Lindström Vanessa D.de Mello Alena Stancacova Matti Uusitupa Mathilde Svendstrup Thorkild I.A.Sørensen Christopher D.Gardner Joan Sabaté Dolores Corella J.Alfredo Martinez Lu Qi Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityChina Department of Global Health School of Public HealthPeking UniversityChina Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education China Global Health Institute Peking University China Department of Epidemiology School of Public Health and Tropical MedicineTulane UniversityNew OrleansLAUSA Department of nutrition Harvard T.H.Chan School of Public HealthBostonMAUSA Department of Endocrinology&nutrition Institut d’Investigacions Biomèdiques August Pi SunyerHospital ClínicBarcelonaSpain CIBER Fisiopatologia de la Obesidad y nutrición(CIBERobn) Instituto de Salud Carlos III(ISCIII)MadridSpain Stanford Prevention Research Center Stanford UniversityStanford CAUSA Human nutrition Unit Faculty of Medicine and Health SciencesPere Virgili Health Research InstituteRovira i Virgili UniversityReusSpain University of navarra Department of Preventive Medicine and Public HealthMedical School&IDISNAPamplonaSpain Department for the Study of Obesity and Diabetes Third Faculty of MedicineCharles UniversityPragueCzech Republic Department of Medicine University of Eastern FinlandKuopioFinland University of Copenhagen Department of NutritionExercise and SportsFaculty of ScienceCopenhagenDenmark Institut national de la Santéet de la Recherche Médicale(Inserm) UMR1048Institute of Metabolic and Cardiovascular DiseasesUniversity of Toulouse and Paul Sabatier UniversityToulouseFrance nestléInstitute of Health Sciences LausanneSwitzerland Department of Human Biology NUTRIM School of Nutrition and Translational Research in MetabolismMaastricht University Medical Centre+MaastrichtNetherlands Section of Metabolic Genetics Novo Nordisk Foundation Center for Basic Metabolic ResearchFaculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark Sorbonne Université Institute of Cardiometabolism and Nutrition(ICAN)Department of NutritionPitié-Salpêtrière HospitalAssistance Publique-

*** strongest locus which associated with type 2 diabetes(T2D)by the common variant rs7903146 is the transcription factor 7-like 2 gene(TCF7L2).We aimed to quantify the interaction of diet/lifestyle interventions and the genetic effect of TCF7L2 rs7903146 on glycemic traits,body weight,or waist circumference in overweight or obese adults in several randomized controlled trials(RCTs).*** October 2016 to May 2018,a large collaborative analysis was performed by pooling individualparticipant data from 7 *** RCTs reported changes in glycemic control and adiposity of the variant rs7903146 after dietary/lifestyle-related interventions in overweight or obese *** treatment interaction models which used the genetic effect encoded by the allele dose and common covariates were applicable to individual participant data in all *** the joint analysis,a total of 7 eligible RCTs were included(n=4,114).Importantly,we observed a significant effect modification of diet/lifestyle-related interventions on the TCF7L2 variant rs7903146 and changes in fasting *** with the control group,diet/lifestyle interventions were related to lower fasting glucose by-3.06(95%CI,-5.77 to-0.36)mg/dL(test for heterogeneity and overall effect:I^(2)=45:1%,pne copy of the TCF7L2 T risk ***,regardless of genetic risk,diet/lifestyle interventions were associated with lower waist ***,there was no significant change for diet/lifestyle interventions in other glycemic control and adiposity traits per one copy of TCF7L2 risk *** findings suggest that carrying the TCF7L2 T risk allele may have a modestly greater benefit for specific diet/lifestyle interventions to improve the control of fasting glucose in overweight or obese adults.

关键词： TCF7L2 weight finding