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International Journal of Minerals,Metallurgy and Materials 2019年第1期26卷 64-75页

作者： Renuprava Dalai siddhartha das Karabi das Department of Metallurgical and Materials Engineering Indian Institute of Technology

Two austenitic Mn steels(Fe-17 Mn and Fe-17 Mn-3 Al(wt%, so as the follows)) were subjected to thermomechanical processing(TMP) consisting of forging followed by solutionization and hot rolling. The rolled samples were annealed at 650 and 800°C to relieve the internal stress and to induce recrystallization. The application of TMP and heat treatment to the Fe-17 Mn/Fe-17 Mn-3 Al steels refined the austenite grain size from 169 μm in the as-solutionized state to 9–13 μm, resulting in a substantial increase in hardness from HV 213 to HV 410 for the Fe-17 Mn steel and from HV 210 to HV 387 for the Fe-17 Mn-3 Al steel. The elastic modulus values, as evaluated by the nanoindentation technique, increased from(175 ± 11) to(220 ± 12) GPa and from(163 ± 15) to(205 ± 13) GPa for the Fe-17 Mn and Fe-17 Mn-3 Al steels, respectively. The impact energy of the thermomechanically processed austenitic Mn steels was lower than that of the steels in their as-solutionized state. The addition of Al to the Fe-17 Mn steel decreased the hardness and elastic modulus but increased the impact energy.

关键词： austenitic manganese steel(AMS) thermomechanical processing(TMP) microstructure property hardness elastic modulus

Combustion and Ball Milled Synthesis of Rare Earth Nano-Sized Ceria Powder

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Materials Sciences and Applications 2011年第5期2卷 416-420页

作者： Ranjan Sen siddhartha das Karabi das 不详

This paper reports a study on nanocrystalline ceria powder prepared by high energy ball-milling and combustion synthesis methods. The combustion synthesis was carried out using ceric ammonium nitrate as oxidizer and citric acid, glycine or citric acid plus glycine as fuel. The minimum crystallite size of ceria powder is obtained by combustion synthesis of ceric ammonium nitrate and citric acid. The ceria powder produced by combustion synthesis of ceric ammonium nitrate and citric acid and glycine has less agglomeration of particles than other techniques.

关键词： Ceramics Ball Milling Combustion Synthesis Nano-Sized Ceria X-Ray Diffraction

The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review

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Acta Pharmaceutica Sinica B 2021年第7期11卷 1740-1766页

作者： Niranjan das siddhartha Kumar Mishra Anusha Bishayee Eunüs S.Ali Anupam Bishayee Department of Chemistry Iswar Chandra Vidyasagar CollegeBelonia-799155TripuraIndia Cancer Biology Laboratory Department of ZoologySchool of Biological SciencesDr.Harisingh Gour Central UniversitySagar-470003Madhya PradeshIndia Pine View School OspreyFL 34229USA Department of Biochemistry and Molecular Genetics Feinberg School of MedicineNorthwestern UniversityChicagoIL 60611USA Lake Erie College of Osteopathic Medicine BradentonFL 34211USA

The phytoecdysteroids(PEs)comprise a large group of biologically-active plant steroids,which have structures similar to those of insect-molting *** are distributed in plants as secondary metabolites that offer protection against phytophagus(plant-eating)*** insects consume the plants containing these chemicals,they promptly molt and undergo metabolic destruction;the insects eventually ***,ecdysteroids are a group of polyhydroxylated ketosteroids that are structurally similar to *** carbon skeleton of ecdysteroids is termed as cyclopentanoperhydro-phenanthrene with aβ-side chain at *** essential characteristics of ecdysteroids are a cis-(5β-H)junction of rings A and B,a 7-en-6-one chromophore,and a trans(14α-OH)junction of rings C and *** only synthesize PEs from mevalonic acid in the mevalonate pathway of the plant cell using acetyl-CoA as a precursor;the most common PE is *** far,over 400 PEs have been identified and reported,and a compilation of 166 PEs originating from 1998 has been previously *** the present review,we have summarized 212 new PEs reported between 1999 and *** have also critically analyzed the biological,pharmacological,and medicinal properties of PEs to understand the full impact of these phytoconstituents in health and disease.

关键词： Phytoecdysteroids Secondary metabolites Antioxidant Anti-inflammatory Antimicrobial Antidiabetic Anticancer activity

Plasma cathepsin L:A prognostic marker for pancreatic cancer

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World Journal of Gastroenterology 2014年第46期20卷 17532-17540页

作者： Nidhi Singh Prasenjit das Surabhi Gupta Vikas Sachdev siddhartha Srivasatava siddhartha Datta Gupta Ravindra Mohan Pandey Peush Sahni Shyam S Chauhan Anoop Saraya Department of Gastroenterology and Human Nutrition All India Institute of Medical SciencesNew Delhi 110029India Deparment of Pathology All India Institute of Medical SciencesNew Delhi 110029India Department of Biostatistics All India Institute of Medical SciencesNew Delhi 110029India Department of GI Surgery All India Institute of Medical SciencesNew Delhi 110029India Department of Biochemistry All India Institute of Medical SciencesNew Delhi110029India

AIM: To assess the prognostic significance of cathepsin L, a cysteine protease that degrades the peri-tumoral tissue, in patients with pancreatic cancer.

关键词： Cathepsin L Pancreatic cancer Overall median survival Plasma

Differentiating Crohn's disease from intestinal tuberculosis

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World Journal of Gastroenterology 2019年第4期25卷 418-432页

作者： Saurabh Kedia Prasenjit das Kumble Seetharama Madhusudhan siddhartha Dattagupta Raju Sharma Peush Sahni Govind Makharia Vineet Ahuja Department of Gastroenterology All India Institute of Medical Sciences Department of Pathology All India Institute of Medical Sciences Department of Radiology All India Institute of Medical Sciences Department of GI Surgery All India Institute of Medical Sciences

Differentiating Crohn's disease(CD) and intestinal tuberculosis(ITB) has remained a dilemma for most of the clinicians in the developing world, which are endemic for ITB, and where the disease burden of inflammatory bowel disease is on the rise. Although, there are certain clinical(diarrhea/hematochezia/perianal disease common in CD; fever/night sweats common in ITB), endoscopic(longitudinal/aphthous ulcers common in CD; transverse ulcers/patulous ileocaecal valve common in ITB), histologic(caseating/confluent/large granuloma common in ITB; microgranuloma common in CD), microbiologic(positive stain/culture for acid fast-bacillus in ITB), radiologic(long segment involvement/comb sign/skip lesions common in CD; necrotic lymph node/contiguous ileocaecal involvement common in ITB), and serologic differences between CD and ITB, the only exclusive features are caseation necrosis on biopsy, positive smear for acid-fast bacillus(AFB) and/or AFB culture, and necrotic lymph node on cross-sectional imaging in ITB. However,these exclusive features are limited by poor sensitivity, and this has led to the development of multiple multi-parametric predictive models. These models are also limited by complex formulae, small sample size and lack of validation across other populations. Several new parameters have come up including the latest Bayesian meta-analysis, enumeration of peripheral blood T-regulatory cells, and updated computed tomography based predictive score. However, therapeutic anti-tubercular therapy(ATT) trial, and subsequent clinical and endoscopic response to ATT is still required in a significant proportion of patients to establish the diagnosis. Therapeutic ATT trial is associated with a delay in the diagnosis of CD, and there is a need for better modalities for improved differentiation and reduction in the need for ATT trial.

关键词： Crohn's disease Intestinal tuberculosis Endoscopy Computed tomographic enterography Granuloma

Preparation and Antibacterial Activity of Silver Nanoparticles

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Journal of Biomaterials and Nanobiotechnology 2011年第4期2卷 472-475页

作者： Ratan das Sneha Gang siddhartha Sankar Nath 不详

Uniform silver nanoparticles have been prepared through the chemical reduction of silver ions by ethanol in presence of sodium linoleate. TEM micrograph shows a uniform distribution of the particles with an average size of 12 nm. Further, the antimicrobial activity of silver nanoparticles shows that these nanoparticles can be used as effective growth inhibitors against Staphylococcus Basillus, Staphylloccoccus Aureus, and Pseudimonas Aureginosa.

关键词： Linoleic Acid Absorption Band Colloid Antimicrobial Microorganisms

Prognostic Role of Preoperative Tricuspid Annular Plane Systolic Excursion (TAPSE) in Mitral Valve Replacement (MVR) for Rheumatic Mitral Stenosis Patients

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World Journal of Cardiovascular Surgery 2024年第8期14卷 115-130页

作者： Satyajit Sharma Muhit Abdullah Md. Noor-E-Elahi Mozumder Munjerin Refat Synthee Md. Zafar-Al-Nimari Anowarul Azim Saikat das Gupta Dewan Iftakher Raza Chowdhury siddhartha Shankar Howlader Noel Crypian Gomes Saleh Ahmed Samir Kumar Biswas Department of Cardiac Surgery National Heart Foundation Hospital & Research Institute (NHFH & RI) Dhaka Bangladesh Department of Cardiac Surgery National Institute of Cardiovascular Diseases & Hospital Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Square Hospital Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Chattogram Bangladesh

Tricuspid annular plane systolic excursion has been proposed as a simple and reproducible parameter for quantitative assessment of the right ventricular ejection fraction. The prognostic importance of preoperative TAPSE in patients with mitral valve replacement for rheumatic mitral stenosis patients is still under focused. Therefore, the objective of the study was to predict the outcome after MVR in rheumatic mitral stenosis patients in relation to preoperative TAPSE. This comparative cross-sectional study was conducted at the Department of Cardiac Surgery, National Heart Foundation Hospital and Research Institute. A total of 72 patients of rheumatic mitral stenosis patients who underwent mitral valve replacement were included in the study. They were divided into two groups: Group A and B. Group A included 36 patients with TAPSE 0.05) except for the preoperative TAPSE. Mean TAPSE of Group A was 13.17 (±1.40) and Group B was 18.61 (±1.57), the difference was statistically significant (p 0.05). Among the postoperative complications, including postoperative atrial fibrillation was higher in Group A (30.56%) than Group B (11.11%), mean ventilation time was higher in Group A (27.78%) than Group B (5.56%), length of intensive care was higher in Group A (33.33%) than Group B (11.12%), and hospital stay was higher in Group A (25.0%) than Group B (5.56%), (p < 0.05). Higher preoperative TASPE could be used as a prognostic tool for MVR in rheumatic mitral stenosis patients in our settings.

关键词： Tricuspid Annular Plane Systolic Excursion Mitral Valve Replacement Rheumatic Heart Disease Mitral Stenosis Right Ventricular Ejection Fraction Postoperative Complications

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考虑非线性侧移的钢板剪力墙设计

钢结构(中英文) 2010年第12期 80-80页

作者： siddhartha Ghosh Farooq Adam Anirudha das

近几年来,加劲钢板剪力墙结构作为一种很有潜力的抗侧力结构不断涌现,但关于此类结构的抗震规范却仍基于弹性设计方法。为满足设计过程高效性和可靠性的要求,提出了一种基于性能的抗震设计方法。对钢板剪力墙的抗震设计方法基于非线性... 详细信息

近几年来,加劲钢板剪力墙结构作为一种很有潜力的抗侧力结构不断涌现,但关于此类结构的抗震规范却仍基于弹性设计方法。为满足设计过程高效性和可靠性的要求,提出了一种基于性能的抗震设计方法。对钢板剪力墙的抗震设计方法基于非线性目标侧移和预选屈服机制。该方法很简捷,能得出更先进的设计标准。以不同钢板长宽比和不同允许侧移条件下某4层结构为例,通过强震下的非线性时程分析,对该方法进行检验。结果表明:实际的非线性侧移与目标侧移非常接近。将峰值处的位移图与所选屈服机制进行了对比。基于上述试验,还需对该方法进行修正。

关键词：钢板剪力墙基于性能的抗震设计基于位移的设计屈服机制塑性设计