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Variation of electron density in spectral broadening process in solid thin plates at 400 nm

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Chinese Physics B 2021年第10期30卷 323-327页

作者： si-yuan xu Yi-Tan Gao Xiao-Xian Zhu Kun Zhao Jiang-Feng Zhu Zhi-Yi Wei School of Physics and Optoelectronic Engineering Xidian UniversityXi’an 710071China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Songshan Lake Material Laboratory Dongguan 523808China

The generation of continuous spectrum centered at 400 nm from solid thin plates is demonstrated in this work.A continuum covering 365 nm to 445 nm is obtained when 125-µJ frequency-doubled Ti:sapphire laser pulses are applied to six thin fused silica plates at 1-kHz repetition *** generalized nonlinear Schrodinger equation simplified for forward propagation is solved numerically,the spectral broadening with the experimental parameters is simulated,and good agreement between simulated result and experimental measurement is *** variation of electron density in the thin plate and the advantage of a low electron density in the spectral broadening process are discussed.

关键词： nonlinear spectral broadening time-dependent nonlinear Schrodinger equation self-phase modu-lation electron density

Attosecond pulse trains driven by IR pulses spectrally broadened via supercontinuum generation in solid thin plates

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Chinese Physics B 2020年第1期29卷 89-94页

作者： Yu-Jiao Jiang Yue-Ying Liang Yi-Tan Gao Kun Zhao si-yuan xu Ji Wang Xin-Kui He Hao Teng Jiang-Feng Zhu Yun-Lin Chen Zhi-Yi Wei School of Physics and Optoelectronic Engineering Xidian UniversityXi'an 710071China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Institute of Applied Micro-Nano Materials School of ScienceBeijing Jiaotong UniversityBeijing 100044China Songshan Lake Material Laboratory Dongguan 523808China

We utilized a set of fused silica thin plates to broaden the spectrum of 1kHz,30 fs Ti:sapphire amplified laser pulses to an *** the compression by chirped mirror pairs,the generated few-cycle pulses were focused onto an argon filled gas *** detected high order harmonics corresponding to a train of 209 as pulses,characterized by the reconstruction of attosecond beating by interference of two-photon transition(RABITT)*** with the conventional attosecond pulse trains,the broad harmonics in such pulse trains cover more energy range,so it is more efficient in studying some typical cases,such as resonances,with frequency resolved *** the solid thin plates can support high power supercontinuum generation,it is feasible to tailor the spectrum to have different central wavelength and spectral width,which will make the RABITT source work in different applications.

关键词： supercontinuum generation high order harmonic generation reconstruction of attosecond beating by interference of two-photon transition(RABITT) attosecond pulse trains

Quality of life in patients with liver cancer after operation:a 2-year follow-up study

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Hepatobiliary & Pancreatic Diseases International 2004年第4期3卷 530-533页

作者： Li Chen, Yong Liu, Guo-Gang Li, si-Feng Tao, yuan xu and Hua Tian Hangzhou, China : Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009 , China Department of Surgery Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310009 China. chenli@***

BACKGROUND:Quality of life (QL) is a concept which reflects the physical, social, and emotional attitudes and behaviours of an individual. QL assessment is becoming in- creasingly recognised as an outcome and predictor for can- cer patients. Although hepatectomy has been widely ac- cepted as treatment of choice to offer a chance of cure for patients with liver cancer, little is known about the subjec- tive clinical results after this operation. This prospective study was designed to evaluate the Pre- and postoperative quality of life in patients with liver cancer. METHODS: The quality of life of 36 consecutive patients was measured using gastrointestinal quality of life index (GQLI) regularly 2 years after the operation, starting with a preoperative measurement. RESULTS: The score of mean preoperative GQLI was 106 ± 13 points, and it was reduced significantly 2-10 weeks after the operation (86-98) (P 0. 05 ). In the patients who survived more than 9 months, the GQLI score was higher than that before the operation. Major hepatectomy (lobectomy and combined segmentectomy) reduced the GQLI score more evidently than did minor hepatectomy (simple segmentec- tomy ) in 2-5 weeks after the operation (P siONS: The assessment of the quality of life is meaningful for patients with liver cancer. Tumor recur- rence, poor liver function and major operation are the most important factors for reducing the quality of life. He- patic resection is justified by its effects on the survival and the quality of life of the patients.

关键词： quality of life liver cancer operation

Assessing pathological features of breast cancer via the multimodal information of multiphoton and Raman imaging

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Chinese Physics B 2023年第11期32卷 151-160页

作者：高冰然陈希文张宝萍 Ivan A.Bratchenko 陈建新王爽许思源 Institute of Photonics and Photon-Technology Northwest UniversityXi’an 710127China Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education Fujian Provincial Key Laboratory of Photonics TechnologyFujian Normal UniversityFuzhou 350007China Laser and Biotechnical Systems Department Samara National Research UniversitySamara 443086Russia

For unveiling the pathological evolution of breast cancer, nonlinear multiphoton microscopic(MPM) and confocal Raman microspectral imaging(CRMI) techniques were both utilized to address the structural and constitutional characteristics of healthy(H), ductal carcinoma in situ(DCIS), and invasive ductal carcinoma(IDC) tissues. MPM-based techniques,including two-photon excited fluorescence(TPEF) and second harmonic generation(SHG), visualized label-free and the fine structure of breast tissue. Meanwhile, CRMI not only presented the chemical images of investigated samples with the K-mean cluster analysis method(KCA), but also pictured the distribution of components in the scanned area through univariate imaging. MPM images illustrated that the cancer cells first arranged around the basement membrane of the duct,then proliferated to fill the lumens of the duct, and finally broke through the basement membrane to infiltrate into the *** the Raman imaging failed to visualize the cell structure with high resolution, it explained spectroscopically the gradual increase of nucleic acid and protein components inside the ducts as cancer cells proliferated, and displayed the distribution pattern of each biological component during the evolution of breast cancer. Thus, the combination of MPM and CRMI provided new insights into the on-site pathological diagnosis of malignant breast cancer, also ensured technical support for the development of multimodal optical imaging techniques for precise histopathological analysis.

关键词： nonlinear multiphoton microscopic imaging Raman microspectral imaging breast cancer

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我国住房公积金制度的公共性流失及治理

企业技术开发 2011年第3期30卷 133-134,152页

作者：袁思旭武汉大学社会保障研究中心湖北武汉430072

住房公积金制度是我国住房保障制度中的一项重要内容,为我国住房改革作出了贡献。但在制度的运行过程中也存在着一些问题,公共性的流失就是其中之一。

关键词：住房公积金制度公共性治理

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Reconstructing in vivo spatially offset Raman spectroscopy of human skin tissue using a GPU-accelerated Monte Carlo platform

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Chinese Physics B 2023年第11期32卷 140-150页

作者：张云鹤朱桓正董泳江曾佳韩新鹏 Ivan A.Bratchenko 张富荣许思源王爽 Institute of Photonics and Photon-Technology Northwest UniversityXi’anShaanxi 710127China Huawei Technologies Co. LtdShenzhenGuangdong 518129China Cardiopulmonary Disease Department Xi’an International Medical Center HospitalXi’an 710100China Laser and Biotechnical Systems Department Samara National Research UniversitySamara 443086Russia

As one type of spatially offset Raman spectroscopy(SORS), inverse SORS is particularly suited to in vivo biomedical measurements due to its ring-shaped illumination scheme. To explain inhomogeneous Raman scattering during in vivo inverse SORS measurements, the light–tissue interactions when excitation and regenerated Raman photons propagate in skin tissue were studied using Monte Carlo simulation. An eight-layered skin model was first built based on the latest transmission parameters. Then, an open-source platform, Monte Carlo e Xtreme(MCX), was adapted to study the distribution of 785 nm excitation photons inside the model with an inverse spatially shifted annular beam. The excitation photons were converted to emission photons by an inverse distribution method based on excitation flux with spatial offsets Δs of 1 mm, 2 mm, 3 mm and 5 mm. The intrinsic Raman spectra from separated skin layers were measured by continuous linear scanning to improve the simulation accuracy. The obtained results explain why the spectral detection depth gradually increases with increasing spatial offset, and address how the intrinsic Raman spectrum from deep skin layers is distorted by the reabsorption and scattering of the superficial tissue constituents. Meanwhile, it is demonstrated that the spectral contribution from subcutaneous fat will be improved when the offset increases to 5 mm, and the highest detection efficiency for dermal layer spectral detection could be achieved when Δs = 2 mm. Reasonably good matching between the calculated spectrum and the measured in vivo inverse SORS was achieved, thus demonstrating great utility of our modeling method and an approach to help understand the clinical measurements.

关键词： Monte Carlo simulation tissue optical model spatially offset Raman spectroscopy

多功能铁铋复合纳米粒对胶质母细胞瘤的放疗增敏作用

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中国组织工程研究 2017年第18期21卷 2821-2827页

作者：牛媛媛于明杜凤移陈思远赵天徐宇浩周倩文许修健江苏大学附属医院神经内科江苏省镇江市212001 江苏大学医学院江苏省镇江市212013 江苏大学附属医院医学影像科江苏省镇江市212001

背景:透明质酸功能化的铁铋复合纳米颗粒是一种有效MRI对比剂,同时又可作为放疗增敏剂。目的:制备透明质酸功能化的铁铋复合纳米颗粒,观察其对胶质母细胞瘤U87MG的放疗增敏作用。方法:通过水热聚醇法制备透明质酸功能化的铁铋复合纳米颗... 详细信息

背景:透明质酸功能化的铁铋复合纳米颗粒是一种有效MRI对比剂,同时又可作为放疗增敏剂。目的:制备透明质酸功能化的铁铋复合纳米颗粒,观察其对胶质母细胞瘤U87MG的放疗增敏作用。方法:通过水热聚醇法制备透明质酸功能化的铁铋复合纳米颗粒HA-Bi IOPs。(1)细胞毒性实验:取对数生长期的人胶质母细胞瘤细胞株U87MG与大鼠血管平滑肌细胞,均以含0,12.5,25,50,100,200,400 mg/L HA-Bi IOPs的培养液培养48 h,计算细胞增殖率;(2)组织相容性实验:在ICR小鼠尾静脉注射HA-Bi IOPs溶液,观察小鼠脏器病理变化;(3)细胞吞噬实验:将HA-Bi IOPs与U87MG细胞共培养6 h,普鲁士蓝观察纳米颗粒是否被细胞吞噬;(4)放疗增敏实验:取对数生长期的U87MG细胞,分组培养:对照组以培养液培养;放疗组分别给予0,3,6,9 Gy的X射线照射;HA-Bi IOPs组分别加入含0,12.5,25,50,100,200,400 mg/L HA-Bi IOPs的培养液;联合组,先加入含0,12.5,25,50,100,200,400 mg/L HA-Bi IOPs的培养液,再给予0,3,6,9 Gy的X射线照射。24 h后,检测细胞增殖率及克隆形成率。结果与结论:(1)不同质量浓度的HA-BiI OPs对血管平滑肌细胞和U87MG细胞增殖无明显影响;(2)尾静脉注射HA-BiI OPs溶液后,小鼠脏器未发生病理变化;(3)共培养6 h后,HA-BiI OPs纳米颗粒可被U87MG细胞吞噬;(4)U87MG细胞增殖率与HA-BiI OPs质量浓度(0-200 mg/L)和放射剂量(0-9 Gy)有明显的线性负相关,尤其是在6 Gy X射线照射下200 mg/L HA-BiI OPs对细胞增殖率下降至(41±7)%。选用100 mg/L HA-BiI OPs、6 Gy X射线照射进行克隆形成实验,联合组U87MG细胞增殖率明显低于空白对照组、放疗组(P<0.05);(5)结果表明,透明质酸功能化的铁铋复合纳米颗粒对胶质母细胞瘤具有显著的放疗增敏作用。

关键词：生物材料纳米材料铁铋复合纳米材料水热聚醇法放疗增敏透明质酸人胶质母细胞瘤细胞生物相容性杀伤肿瘤细胞增殖率

16.48% Efficient solution-processed CIGS solar cells with crystal growth and defects engineering enabled by Ag doping strategy

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Journal of Energy Chemistry 2025年第1期100卷 59-65页

作者： Mengyu xu Shaocong Yan Ting Liang Jia Jia Shengjie yuan Dongxing Kou Zhengji Zhou Wenhui Zhou Yafang Qi Yuena Meng Litao Han sixin Wu Key Laboratory for Special Functional Materials of MOE National & Local Joint Engineering Research Centre for High-efficiency Display and Lighting Technology School of Nanoscience and Materials Engineering Henan University

Solution-processed Cu（In,Ga）Se2（CIGS） solar cells suffer from serious carrier recombination and power conversion efficiency（PCE） loss because of the poor film properties and easy formation of ***, we propose Ag&Se co-selenization strategy to enhance the crystallization and passivate harmful defects of the CIGS films. The formation of Ag-Se phase during the selenization process enables the formation of large grains and suppresses the deep level defects. It is found that Ag doping can enlarge the depletion region width, lower the Urbach energy and prolong the carrier lifetime. As a result, a champion solution-processed CIGS solar cell presents a high efficiency of 16.48% with the highly improved opencircuit voltage（VOC） of 662 m V and fill factor（FF） of 75.8%. This work provides an efficient strategy to prepare high quality solution-processed CIGS films for high-performance CIGS solar cells.

关键词： CIGS solar cells Solution-processed method Ag doping Crystal growth Defects engineering

呼和浩特市2010-2014年肺结核流行病学特征分析

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疾病监测与控制 2017年第10期11卷 788-790页

作者：刘思远许向云呼和浩特市结核病防治所内蒙古呼和浩特010030 呼和浩特市疾病预防控制中心

目的了解呼和浩特市2010-2014年肺结核流行病学特征,为制定防控策略提供科学依据。方法对呼和浩特市2010-2014年法定传染病报告系统的肺结核病例数据资料进行描述性流行病学统计分析。结果呼和浩特市2010-2014年共报告肺结核病例5 204例... 详细信息

目的了解呼和浩特市2010-2014年肺结核流行病学特征,为制定防控策略提供科学依据。方法对呼和浩特市2010-2014年法定传染病报告系统的肺结核病例数据资料进行描述性流行病学统计分析。结果呼和浩特市2010-2014年共报告肺结核病例5 204例,2010年发病率为53.77/10万,2011年发病率为45.11/10万,2012年发病率为39.68/10万,2013年发病率为28.05/10万,2014年发病率为22.26/10万,呈逐年下降趋势;每年3、4、11、12月报告的发病例数较多。﹥55岁人群为发病高危人群,占报告病例总数的48.14%;职业分布中农民所占比例最大,为50.56%;男性发病所占比例明显高于女性。农区发病率高于市区。结论呼和浩特市肺结核疫情形势不容乐观,今后应加强重点人群的肺结核防治工作。

关键词：肺结核流行病学分析