检索结果-南通市图书馆

Combination of propofol and dezocine to improve safety and efficacy of anesthesia for gastroscopy and colonoscopy in adults: A randomized, double-blind, controlled trial

引用

World Journal of Clinical Cases 2019年第20期7卷 3237-3246页

作者： Xue-Ting Li Chao-Qun Ma si-hua qi Li-Min Zhang Department of Anaesthesiology The Fourth Affiliated HospitalHarbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Neurosurgery Harbin 242 HospitalHarbin 150066Heilongjiang ProvinceChina

BACKGROUND Gastroscopy and colonoscopy are important and common endoscopic methods for the diagnosis and treatment of gastrointestinal and colorectal ***,endoscopy is usually associated with adverse reactions such as nervousness,nausea,vomiting,choking cough,and *** discomfort,such as vomiting,coughing,or body movement,may lead to aggravation of a preexisting condition or even interruption of examination or treatment,especially in some critically ill patients with physiological dysfunction(e.g.,cardiovascular or respiratory disease).The optimal methods for inducing analgesia and sedation in endoscopy are areas of ongoing debate;nevertheless,determining an appropriate regimen of sedation and analgesia is *** To evaluate the effects of propofol combined with dezocine,sufentanil,or fentanyl in painless gastroscopy and *** Four hundred patients were randomly assigned to one of four groups for anesthesia:intravenous dezocine,sufentanil,fentanyl,or *** was administered intravenously for induction and maintenance of *** The dosage of propofol in the dezocine group was significantly lower than those in other groups(Psive,immobile patient whose airway requires maintenance to a fully recovered patient)after eye opening in the dezocine group were significantly higher than those in other groups(Psignificantly lower than those in other groups(Psignificantly more stable at various time points(before dosing,disappearance of eyelash reflex,and wakeup)than those in other groups(Psignificantly lower than those in other groups(P<0.01).Additi

关键词： Anesthesia Dezocine Propofol Gastroscopy Colonoscopy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sap Flow of Populus euphratica in a Desert Riparian Forest in an Extreme Arid Region During the Growing Season

引用

Journal of Integrative Plant Biology 2007年第4期49卷 425-436页

作者： Jian-hua si qi Feng Xiao-You Zhang Zong-qiang Chang Yong-Hong Su Hai-Yang Xi Cold and Arid Region Environmental and Engineering Research Institute the Chinese Academy of Sciences Alashan Desert Eco-hydrology Experimental Research Station Lanzhou 730000 China

In the present study, the heat pulse technique was applied to investigate the stem sap flow of Populus euphratica in a desert riparian forest in an extreme arid region from April to October 2003 and from May to October 2004. The experimental sites were in qidaoqiao （101 °10′ E, 41°59′ N） and Bayantaolai farm （101°14′ E, 42°01′ N） in Ejina county, in the low reaches of the Heihe River, China. The results indicated that the diurnal change in the velocity of sap flow showed minor fluctuations. At night, the rising of sap flow could be observed in the main tree species because of root pressure. During the growing season, the maximum average velocity was observed in July, followed by August, and the same velocity was observed in September and May; the minimum velocity was observed in October. The transpiration from June to August during the growing season accounted for approximately 70% of the annual total transpiration. The sap flow velocity of P. euphratica trees of different ages could be arranged in the order： 15 yr 〉 25 yr 〉 50 yr. Sap flow velocity was closely related to changes in micrometeorological factors, with average sap flow velocity showing a significant linear correlation with net radiation, air temperature and relative humidity.

关键词： desert riparian forest extreme arid region heat-pulse technique Populus euphratica sap flow velocity.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

硫肽类抗生素诺卡沙星I的结构改造研究进展

引用

药物生物技术 2020年第2期27卷 177-181页

作者：花私齐赵玲吴旭日中国药科大学生命科学与技术学院化学生物学研究室江苏南京211198

诺卡氏菌Nocardia *** 202099合成的次级代谢产物诺卡沙星Ⅰ是一种杀菌活性超强,作用靶点和机制新颖的硫肽类抗生素。多年来,诺卡沙星Ⅰ以及其类似物或衍生物一直是新型抗生素开发的热点目标化合物。但是,水溶性差是诺卡沙星Ⅰ成药的关... 详细信息

诺卡氏菌Nocardia *** 202099合成的次级代谢产物诺卡沙星Ⅰ是一种杀菌活性超强,作用靶点和机制新颖的硫肽类抗生素。多年来,诺卡沙星Ⅰ以及其类似物或衍生物一直是新型抗生素开发的热点目标化合物。但是,水溶性差是诺卡沙星Ⅰ成药的关键限制因素。为解决水溶性差的难题,科学家们采取了化学半合成、生物转化以及物理转化的方法对诺卡沙星Ⅰ的结构进行改造,以期增加其水溶性,提高成药性。本文将对诺卡沙星Ⅰ的结构改造进行概述,为水溶性差的抗生素的成药研究提供参考。

关键词：诺卡沙星Ⅰ 诺卡沙星类似物结构改造水溶性生物转化化学半合成

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

十二烷基羟丙基磺基甜菜碱对产膜表皮葡萄球菌粘附作用的影响

引用

日用化学工业 2017年第9期47卷 497-501页

作者：段强军花私齐官妍安徽中医药大学安徽合肥230038 中国药科大学江苏南京211198

通过表面活性剂十二烷基羟丙基磺基甜菜碱(DSB)对表皮葡萄球菌生物被膜菌粘附的抑制作用研究,为抗由表皮葡萄球菌生物被膜菌引起的相关感染提供新的探索方向和治疗途径。以万古霉素为阳性对照,利用XTT减低法评价DSB对表皮葡萄球菌初始... 详细信息

通过表面活性剂十二烷基羟丙基磺基甜菜碱(DSB)对表皮葡萄球菌生物被膜菌粘附的抑制作用研究,为抗由表皮葡萄球菌生物被膜菌引起的相关感染提供新的探索方向和治疗途径。以万古霉素为阳性对照,利用XTT减低法评价DSB对表皮葡萄球菌初始粘附的影响。发现质量浓度为64 mg/L的DSB对表皮葡萄球菌初始粘附有显著的抑制作用;用质量浓度为512,256和128 mg/L的DSB对实验材料预处理后,对表皮葡萄球菌初始粘附的抑制作用明显。结果表明,DSB对表皮葡萄球菌形成生物被膜的初始粘附过程具有显著的抑制作用。

关键词：表面活性剂十二烷基羟丙基磺基甜菜碱粘附表皮葡萄球菌生物被膜

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

一种适用于卫星电视直播的用户区域化管理方法

引用

通信技术 2020年第8期53卷 1959-1964页

作者：赵欢司华奇李宗元东方红卫星移动通信有限公司重庆401120 老挝亚太卫星有限公司老挝万象01000

卫星电视直播(DTH)与传统数字有线或地面广播电视相比,一大优势在于其广阔的覆盖面积与价格低廉的用户接收终端。对于国土面积与人口都相对较少的广大第三世界国家,DTH的成功运营往往依赖于多个不同国家或地区的业务开展。而出于国家政... 详细信息

卫星电视直播(DTH)与传统数字有线或地面广播电视相比,一大优势在于其广阔的覆盖面积与价格低廉的用户接收终端。对于国土面积与人口都相对较少的广大第三世界国家,DTH的成功运营往往依赖于多个不同国家或地区的业务开展。而出于国家政治与宣传层面考虑,或基于各国语言文化传统,各国受众对电视节目的收视偏好,尤其是节目排序等直观感受,往往都会有不同需求。传统的DVB-si标准难以实现多个不同地区的区域化管理。提出了一种适用于DTH电视直播的区域化管理规则,通过DTH前端系统与用户终端配合,可实现DTH节目排序与增值业务的区域化管理,较好地解决这一问题,经实践具有一定的商业价值。

关键词：卫星电视直播区域化管理节目排序增值业务

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stepwise assembly to construct stable copper(I) cluster-based circularly polarized luminescent MOFs

引用

Science China Chemistry 2025年

作者： Jing-Wen Xie Meng-Ting Wang Yan Jin si Li Jian-hua qin Shuang-Quan Zang Tomas C.W.Mak College of Chemistry Henan Key Laboratory of Crystalline Molecular Functional Materials Zhengzhou University College of Chemistry and Chemical Engineering Luoyang Normal University Department of Chemistry The Chinese University of Hong Kong

Circularly polarized luminescence （CPL） materials have been extensively studied in recent years owing to their widespread applications in 3D display,optical storage,optical anti-counterfeiting,and biological imaging,***（I） clusters have emerged as a promising candidate for CPL materials,driven by their cost-effectiveness,superior luminescent properties,precise structure,and low ***,the poor environmental stability of copper（I） clusters renders their synthesis and preservation challenging,thereby significantly impeding their ***,we have designed and synthesised a chiral double-coordinated ligand in order to construct copper（I） cluster nodes that can be further *** anticipated,by utilizing stepwise assembly strategy,a Cu4cluster node co-modified by chiral alkynyl ligands and triphenylphosphine was further assembled with Cd2+ions to obtain 2D layers structure,L/*** L/D-Cu4-Cd exhibits excellent stability and optical properties,including bright yellow emission,solvent-responsive luminescence,and CPL activity with a maximum glumup to 2.0×10-3,which shows potential applications in the WLED and *** interestingly,the material also exhibits deflection ability towards different wavelengths of linearly polarized light,showing certain potential in the preparation of circular polarizer.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

引用

Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-hua qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

公平竞争审查、新质生产力与企业数字化转型

引用

经济问题 2025年第1期 1-14页

作者：师博郭思琪南京大学数字经济与管理学院江苏苏州215163 西北大学经济管理学院陕西西安710127

数字经济是新质生产力的综合质态。公平竞争审查制度作为高水平社会主义市场经济体制的重要组成部分,能够激发企业创新活力和数字化转型动力,从而推动新质生产力发展。采用双重差分法评估公平竞争审查制度对上市公司数字化转型的影响。... 详细信息

数字经济是新质生产力的综合质态。公平竞争审查制度作为高水平社会主义市场经济体制的重要组成部分,能够激发企业创新活力和数字化转型动力,从而推动新质生产力发展。采用双重差分法评估公平竞争审查制度对上市公司数字化转型的影响。研究发现,该制度能够显著提升行政垄断程度高地区的企业数字化转型水平,并且以促进“底层技术运用”为支点撬动了企业数字化转型,凸显了竞争政策的基础性作用。机制检验表明,公平竞争审查制度能够通过促进创新要素流动、优化信贷资源配给、完善数字发展制度环境打通束缚新质生产力发展的“堵点”和“卡点”,从而驱动企业数字化转型。围绕公平竞争审查标准、方式和目标的异质性分析发现,政策呈现出对民营企业、较小规模企业的所有制和规模“偏好”,并且对于制度性交易成本较高的企业作用更加明显;地区自我审查与外部监督机制较为完善时,政策能够更好发挥作用。最后产业政策的叠加效果检验显示,中央与省级产业政策均与公平竞争审查形成了制度合力,有效市场和有为政府协同推进了企业数字化进程。研究结论能够为公平竞争审查制度促进各类先进生产要素向发展新质生产力集聚提供理论支撑和实证依据。

关键词：高质量发展高水平社会主义市场经济体制数字经济行政性垄断

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigations of liquid-liquid transitions in metallic melts by fast differential scanning calorimetry

引用

Science China(Physics,Mechanics & Astronomy) 2025年

作者： qi Cheng Yonghao Sun Weihua Wang Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering Peking University School of Physics and Electronic Information Anhui Normal University Institute of Physics Chinese Academy of Sciences Songshan Lake Materials Lab

Liquid-liquid transition in metallic melts is an intriguing phenomenon often confused with liquid-liquid separation, oxidation or precipitation. Here, we employ a state-of-the-art ultrafast chip-based differential scanning calorimeter to investigate the thermal behavior of six metallic melts, ranging from unary to quinary systems, at temperatures above their liquidus. Calorimetric signals of liquid-liquid transition vary across systems: Sn melts showed no direct endothermic or exothermic events, though liquid-liquid transition influenced solidification and melting temperatures, while Yb-Zn melts exhibited an exothermic peak during cooling,indicating liquid-liquid transition. Thermal signals in other systems including Li, Pd-Ni-P, Yb-Mg-Zn-Cu and Au-Ag-Pd-Cu-si,are primarily driven by compositional changes. Our in-situ analysis provides new insights into the structural and compositional evolution of metallic melts, offering significant implications for the design and processing of novel materials.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

EDTA-enhanced phytoremediation of lead contaminated soil by Bidens maximowicziana

引用

Journal of Environmental Sciences 2007年第12期19卷 1496-1499页

作者： WANG Hong-qi LU si-jin LI hua YAO Zhi-hua College of Water Sciences Beijing Normal University Beijing 100875 China.

Phytoremediation is a potential cleanup technology for the removal of heavy metals from contaminated soils. Bidens is a new Pb hyperaccumulator, which not only has remarkable tolerance to Pb but also extraordinary accumulation capacity for Pb. The maximum Pb concentration was 1509.3 mg/kg in roots and 2164.7 mg/kg in overground tissues. The Pb distribution order in the B. was： leaf 〉 stem 〉 root. The effect of amendments on phytoremediation was also studied. The mobility of soil Pb and the Pb concentrations in plants were both increased by EDTA application. Compared with CK （control check）, EDTA application promoted translocation of Pb to overground parts of the plant. The Pb concentrations in overground parts of plants was increased from 24.23-680.56 mg/kg to 29.07-1905.57 mg/kg. This research demonstrated that B. maximowicziana appeared to be suitable for phytoremediation of Pb contaminated soil, especially, combination with EDTA.

关键词： phytoremediation Bidens maximowicziana lead amendment EDTA

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：