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Endosulfan residues and farmers’replacement behaviors of endosulfan in the north-west inland cotton region

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 35-47页

作者： shuyan Zhou Yang Zhang Jingjing Wang Shikun Cheng Fuyan Zhuo Yun hong School of Energy and Environmental Engineering University of Science and Technology Beijing 100083China Foreign Environmental Cooperation Center Ministry of Ecology and Environment of the People’s Republic of ChinaBeijing 100035China United Nations Development Programme in China Beijing 100600China National Agro-Tech Extension and Service Center Beijing 100125China

We assessed the situation of endosulfan residues in cotton fields after the endosulfan ban came into effect and the current knowledge,attitude,and practice(KAP)of cotton farmers on the phase-out of endosulfan and the application of alternative *** samples(n=91)of cotton fields were collected from the major cotton-producing areas in China,namely the north-west inland cotton region,and the endosulfan residues were analyzed.A KAP survey was carried out for cotton farmers,and 291 questionnaires were *** influences of gender,age,education background,cotton planting years,publicity and training,income sources,and other factors on cotton farmers’KAP were *** results showed that endosulfan sulfate was the main endosulfan residue in the soil,followed byβ-endosulfan andα-endosulfan,the average residual contents were 0.569,0.139,and 0.060μg/kg,*** results of the KAP study showed that cotton farmers scored low on knowledge about the phase-out of endosulfan and the application of alternative technologies but high on attitude and *** number of family members,years of cotton planting,age,and the cottonplanting area had different degrees of influence on KAP *** training could significantly improve the KAP scores of cotton farmers;training should be more targeted and designed reasonably for key groups,such as men and the population under 30,followed by training them to use pesticides *** large-scale cotton growers,training should focus on green prevention and control technologies.

关键词： Cotton fields Endosulfan residues Farmers KAP survey Replacement behaviours

The Effect of Xu’s Influenza Decoction Combined with Oseltamivir on Influenza A:A Propensity Score Matching Study

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Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 1-9页

作者： Tianxi Chen shuyan Fu Fengyuan Tian Qiushuang Li hongyu Ling Yijie Lou Jun Tang hong Zheng Basic Medical School Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Department of Infectious Diseases First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina First School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Center of Clinical Evaluation and Analysis First Affiliated Hospital of Zhejiang Chinese Medicine UniversityHangzhou 31006ZhejiangChina Department of General Practice First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 31006ZhejiangChina

Background:The resurgence of seasonal influenza virus circulation has been seen in 2021-2022 after the tempo-rary suppression in *** inhibitors(NAIs)are widely applied in the clinical treatment of influenza A despite several ***:To access the efficacy of Xu’s influenza decoction(XID)in combination therapy with oseltamivir for the treatment of influenza ***:In this retrospective cohort study,the eligible participants were diagnosed with influenza A between June 1,2018,and May 30,2022,in the First Affiliated Hospital of Zhejiang Chinese Medical *** to whether Xu’s influenza decoction was applied,patients were divided into two groups:treated with or without *** score matching(PSM)was used to further adjust the covariates between *** primary outcome was to compare time to defervescence via K-M curves,Breslow tests,and Cox regression *** Cox proportional hazards model,a univariate analysis was performed to obtain preliminary results,while a further multivariate analysis was conducted to study the independent factors that influence *** analysis was conducted according to body temperature and time from onset to *** secondary outcome consisted of routine blood and C-reactive protein(CRP),length of stay,and medical ***:A total of 336 patients with influenza A were enrolled in this study(i.e.,163 patients in the XID+oseltamivir group;173 patients in the oseltamivir group).After 1:1 matching via PSM,230 patients meeting the criteria were included in the analysis,with 115 in each *** XID+oseltamivir group had shorter time to defervescence(36 h vs 44 h,P=0.011),shorter length of stay(3 days vs 4 days,P=0.018),and higher defervescence possibility(HR=1.384,95%CI:1.054-1.818).Subgroup analysis indicated that for patients during non-window period(≥48 h)with medium-grade fever(38.1℃-39℃),the XID+oseltamivir combination therapy reduced time to defervescence

关键词： Influenza A Xu’s influenza decoction Oseltamivir Time to defervescence,Cox regression Propensity score matching Cohort study

DYNAMICS FOR A CHEMOTAXIS MODEL WITH GENERAL LOGISTIC DAMPING AND SIGNAL DEPENDENT MOTILITY

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Acta Mathematica Scientia 2024年第3期44卷 1046-1063页

作者：涂馨予穆春来邱蜀燕张静 School of Mathematics and Statistics Southwest UniversityChongqing400715China Department of Applied Mathematics The Hong Kong Polytechnic UniversityHung HomHong KongChina College of Mathematics and Statistics Chongqing UniversityChongqing401331China School of Sciences Southwest Petroleum UniversityChengdu610500China

In this paper,we consider the fully parabolic Chemotaxis system with the general logistic source{ut=Δ(γ(v)u)+λu-μu^(k),x∈Ω,t>0,vt=△v+wz,x∈Ω,t>0,wt=-wz,x∈Ω,t>0,zt=△z-z+u,x∈Ω,t>0 whereΩ⊂ℝn(n≥1)is a smooth and bounded domain,λ≥0,μ≥0,κ>1,and the motility function satisfies thatγ(v)∈C3([0,∞)),γ(v)>0,γ′(v)≤0 for all v≥*** the Neumann boundary condition,we obtain the global boundedness of solutions if one of the following conditions holds:(i)λ=μ=0,1≤nλ3;(ii)λ>0,μ>0,combined withκ>1,1≤n≤3 or k>n+2/4,,n>***,we prove that the solution (u, v, w, z) exponentially converges to the constant steady state ((λ/μ)1/k-1,∫Ωv0dx+∫Ωw0dx/|Ω|,0,(λ/μ)1/k-1).

关键词： chemotaxis signal-dependent motility logistic source boundedness asymptotic behavior

柴胡加龙骨牡蛎汤对抑郁症肝郁气滞型大鼠肝脏sEH表达的影响

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辽宁中医药大学学报 2024年第8期26卷 12-17页

作者：洪捷蔡萧君李树延黑龙江省中医药科学院黑龙江哈尔滨150036

目的基于肝脏可溶性环氧化物水解酶(soluble epoxide hydrolase,sEH)表达变化探讨柴胡加龙骨牡蛎汤对肝郁大鼠的影响。方法选取50只SPF级SD雄性大鼠,10只作为空白组,40只建立慢性温和不可预知性刺激(CUMS)大鼠模型,成模后随机分为模型... 详细信息

目的基于肝脏可溶性环氧化物水解酶(soluble epoxide hydrolase,sEH)表达变化探讨柴胡加龙骨牡蛎汤对肝郁大鼠的影响。方法选取50只SPF级SD雄性大鼠,10只作为空白组,40只建立慢性温和不可预知性刺激(CUMS)大鼠模型,成模后随机分为模型组、氟西汀组、柴胡加龙骨牡蛎汤低剂量组、柴胡加龙骨牡蛎汤高剂量组,每组各10只。连续灌胃给药4周,1次/d,分别于造模前、成模后及给药后进行旷场实验、悬尾实验、强迫游泳实验评估大鼠抑郁状态,实时荧光定量聚合酶链式反应(RT-PCR)检测大鼠肝脏组织中sEH mRNA表达,蛋白免疫印迹法(Western blot)定量检测大鼠肝脏组织中sEH蛋白表达。结果与空白组比较,模型组大鼠活动总路程、悬尾挣扎时间均明显缩短(P<0.05),游泳不动时间明显延长(P<0.05),肝sEH蛋白含量及mRNA表达水平均明显升高(P<0.05)。与模型组比较,氟西汀组、柴胡加龙骨牡蛎汤低剂量组(CLMT-L)、柴胡加龙骨牡蛎汤高剂量组(CLMT-H)的活动总路程、悬尾挣扎时间均明显延长(P<0.05),游泳不动时间均明显缩短(P<0.05),肝sEH蛋白含量及mRNA表达水平均明显降低(P<0.05)。干预后,氟西汀组、CLMT-L组、CLMT-H组活动总路程、悬尾挣扎时间均明显长于干预前(P<0.05),游泳不动时间明显短于干预前(P<0.05)。结论抑郁发生后可以增加sEH在肝脏内的表达,而柴胡加龙骨牡蛎汤能显著改善肝郁气滞大鼠的抑郁样行为,并降低肝脏sEH的表达,其作用机制可能与肝sEH含量变化有关。

关键词：柴胡加龙骨牡蛎汤抑郁症肝郁气滞可溶性环氧化物水解酶肝脏

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基质金属蛋白酶7在肝癌细胞迁移及免疫细胞浸润中的作用与预后价值

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临床肝胆病杂志 2024年第7期40卷 1420-1427页

作者：刘淑岩杨其昌沈屹周虹钱金锋南通市第一人民医院病理科江苏南通226014

目的评估基质金属蛋白酶7(MMP7)在肝癌细胞迁移及免疫细胞浸润中的作用及预后价值。方法分别构建下调或上调靶基因MMP7的MMP7_siRNA、pMMP7转染肝癌细胞株(MHCC97H)。采用RT-qPCR、Western Blot分别检测细胞中靶基因mRNA及蛋白的表达水... 详细信息

目的评估基质金属蛋白酶7(MMP7)在肝癌细胞迁移及免疫细胞浸润中的作用及预后价值。方法分别构建下调或上调靶基因MMP7的MMP7_siRNA、pMMP7转染肝癌细胞株(MHCC97H)。采用RT-qPCR、Western Blot分别检测细胞中靶基因mRNA及蛋白的表达水平。扫描电镜和Transwell小室实验分别观察细胞伪足和迁移能力的变化,并采用生物信息学的方法,在TCGA、TIMER数据库分析MMP7与免疫细胞及肝癌患者免疫浸润评分之间的相关性,并进一步研究MMP7与肝癌患者预后的相关性。相关性分析采用Spearman方法。Sanger Box在线工具评估MMP7在肝癌总体生存期、疾病特异性生存期方面的意义。Kaplan-Meier法绘制生存曲线,Log-rank检验评估不同组样本之间的预后差异。结果构建的MMP7_siRNA、pMMP7转染MHCC97H细胞后均能有效下调或上调靶基因MMP7的表达,在MHCC97H细胞中MMP7被干扰后细胞伪足明显减少,并且变短,但是过表达MMP7之后细胞表面丝状伪足数量明显增多,并且伪足长度变长,放射状排列。Transwell小室结果发现,MMP7_siRNA2能够显著降低细胞迁移能力(P<0.05),而转染pMMP7后,细胞迁移能力显著增加(P<0.05)。MMP7的表达与B淋巴细胞(r=0.37)、CD4+T淋巴细胞(r=0.40)、中性粒细胞(r=0.49)、巨噬细胞(r=0.49)、树突状细胞(r=0.47)显著相关(P值均<0.05)。在TCGA数据库中,基于总体生存期最佳截断值将肝癌患者分成MMP7高表达组(n=267)和MMP7低表达组(n=146),结果发现,MMP7高表达组的总体生存期明显低于MMP7低表达组(P<0.05);基于疾病特异性生存期最佳截断值将肝癌患者分成MMP7高表达组(n=257)和MMP7低表达组(n=145),结果发现,MMP7高表达组的疾病特异性生存期也低于MMP7低表达组(P<0.05)。结论MMP7促进了肝癌细胞的迁移,并在免疫细胞浸润中发挥主要作用,MMP7的表达也与肝癌的预后具有明显相关性。

关键词：肝肿瘤基质金属蛋白酶7 细胞运动

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贾春生教授治疗肘管综合征临床经验总结

Journal of Acupuncture and Tuina Science 2024年第2期22卷 167-172页

作者：侯献兵张海燕刘淑彦赵建勇贾春生洪珏(翻译) Cangzhou Hospital of Integrated TCM-WM Hebei ProvinceCangzhou 061001China Hebei University of Chinese Medicine Shijiazhuang 050091China 不详

总结贾春生教授采用耳针沿皮透刺法、普通针刺、火针、中药内服等多种中医疗法论治肘管综合征的临床经验,传承其分经、分期论治,重视患者体质状态,兼顾整体治疗的学术特色,从而为肘管综合征的科普教育和临床治疗提供参考。

关键词：针刺疗法针灸疗法耳针火针疗法针药并用肘管综合征名医经验贾春生

粤港澳大湾区智慧物流人才培养现状与路径研究

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物流科技 2024年第13期47卷 176-180页

作者：王春生张良卫丁红周淑妍广州软件学院数字经济与管理学院广东广州510990 澳门城市大学金融学院中国澳门999078

为了切实掌握粤港澳大湾区高校智慧物流人才培养现状,随机抽取了30所代表高校,对其智慧物流人才培养现状进行深入调查。问卷数据显示,高校思想层面上认识到智慧物流人才培养的重要性,并在物流专业人才培养方案、课程设置等方面初探式的... 详细信息

为了切实掌握粤港澳大湾区高校智慧物流人才培养现状,随机抽取了30所代表高校,对其智慧物流人才培养现状进行深入调查。问卷数据显示,高校思想层面上认识到智慧物流人才培养的重要性,并在物流专业人才培养方案、课程设置等方面初探式的增加智慧物流方向相关内容。同时,多数高校也初步开设了智慧物流方向相关课程并提供了相关政策支持。但是,多数学校具有人工智能相关背景的物流老师占比较低。截止问卷调查时,多数高校学生以传统物流岗位实习为主,高校对智慧物流相关方向实习岗位的需求强烈。为了填补智慧物流人才的缺口,培养满足企业需求的高质量智慧物流人才,大湾区高校应该着重在“学科专业设置、人才培养方案、教师团队建设、产教融合、校企合作”等方面进行优化。文章结论为高校开展智慧物流人才培养提供数据支持和意见建议,为推动粤港澳大湾区发展智慧物流提供数据提供参考。

关键词：粤港澳大湾区智慧物流人才培养现状与路径研究

Field effect transistor-based tactile sensors: From sensor configurations to advanced applications

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InfoMat 2023年第1期5卷 1-61页

作者： Jian Wang shuyan Xu Congcong Zhang Ailing Yin Mingyuan Sun hongru Yang Chenguo Hu hong Liu Institute for Advanced Interdisciplinary Research(iAIR) Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of ShandongUniversity of JinanJinanPeople's Republic of China Department of Applied Physics State Key Laboratory of Power Transmission Equipment&System Security and New TechnologyChongqing UniversityChongqingPeople's Republic of China Department of Physics School of Physical Science and TechnologyUniversity of JinanJinanPeople's Republic of China State key Laboratory of Crystal Materials Shandong UniversityJinanPeople's Republic of China

The past several decades have witnessed great progress in high-performance field effect transistors(FET)as one of the most important electronic *** the same time,due to their intrinsic advantages,such as multiparameter accessibility,excellent electric signal amplification function,and ease of large-scale manufacturing,FET as tactile sensors for flexible wear-able devices,artificial intelligence,Internet of Things,and other fields to per-ceive external stimuli has also attracted great attention and become a significant field of general *** importantly,FET has a unique three-terminal structure,which enables its different components to detect external mechanics through different sensing *** one hand,it provides an important platform to shed deep insights into the underlying mechanisms of the tactile *** the other hand,these properties could in turn endow excellent components for the construction of tactile matrix sensor arrays with high *** special emphasis on the configuration of FETs,this review classified and summarized structure-optimized FET tactile sensors with gate,dielectric layer,semiconductor layer,and source/drain electrodes as sensing active components,*** working principles and the state-of-the-art protocols in terms of high-performance tactile sensors are detail discussed and highlighted,the innovative pixel distribution and integration analysis of the transistor sensor matrix array concerning flexible electronics are also *** hope that the introduction of this review can provide some inspiration for future researchers to design and fabricate high-performance FET-based tactile sensor chips for flexible electronics and other fields.

关键词： field-effect transistor flexible electronics tactile matrix sensor array tactile sensors

H_3PW_(12)O_(40)对TiO_2纳米管光伏效应影响的研究

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化工新型材料 2018年第3期46卷 190-193页

作者：孙淑艳孙虹罗新泽历凤燕伊犁师范学院化学与环境科学学院伊犁835000 东北师范大学化学学院长春130024

将H_3PW_(12)O_(40)(PW_(12))用电沉积法沉积在TiO_2纳米管薄膜上,得到PW_(12)-TiO_2纳米管复合薄膜,再将PW_(12)-TiO_2纳米管复合薄膜组装成光伏电池,测定其光电转换效率。结果表明:用PW_(12)修饰的TiO_2纳米管薄膜的光电转换效率达到3... 详细信息

将H_3PW_(12)O_(40)(PW_(12))用电沉积法沉积在TiO_2纳米管薄膜上,得到PW_(12)-TiO_2纳米管复合薄膜,再将PW_(12)-TiO_2纳米管复合薄膜组装成光伏电池,测定其光电转换效率。结果表明:用PW_(12)修饰的TiO_2纳米管薄膜的光电转换效率达到3.62%,是未修饰TiO_2纳米管薄膜(0.36%)的10倍左右,说明在TiO_2纳米管薄膜光电转换时PW_(12)能有效地抑制光生电子-空穴的复合,起到了储存和转移电子的作用,从而极大地提高了TiO_2纳米管薄膜的光电转换效率。

关键词： TiO2纳米管光伏电池多酸光电转换效率