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Cotton leaf disease detection method based on improved SSD

International Journal of Agricultural and Biological Engineering 2024年第2期17卷 211-220页

作者： Wenjuan Guo shuo feng Quan feng Xiangzhou Li Xueze Gao College of Mechanical and Electrical Engineering Gansu Agricultural UniversityLanzhou 730070China School of Cyber Security Gansu University of Political Science and LawLanzhou 730070China College of Mechanical and Electrical Engineering Sichuan Agricultural UniversityYa’an 625014China

In response to the problems of numerous model parameters and low detection accuracy in SSD-based cotton leaf disease detection methods,a cotton leaf disease detection method based on improved SSD was proposed by combining the characteristics of cotton leaf ***,the lightweight network MobileNetV2 was introduced to improve the backbone feature extraction network,which provides more abundant semantic information and details while significantly reducing the amount of model parameters and computing complexity,and accelerates the detection speed to achieve real-time ***,the SE attention mechanism,ECA attention mechanism,and CBAM attention mechanism were fused to filter out disease target features and effectively suppress the feature information of jamming targets,generating feature maps with strong semantics and precise location *** test results on the self-built cotton leaf disease dataset show that the parameter quantity of the SSD_MobileNetV2 model with backbone network of MobileNetV2 was 50.9%of the SSD_VGG model taking VGG as the *** with SSD_VGG model,the P,R,F1 values,and mAP of the MobileNetV2 model increased by 4.37%,3.3%,3.8%,and 8.79%respectively,while FPS increased by 22.5 frames/*** SE,ECA,and CBAM attention mechanisms were introduced into the SSD_VGG model and SSD_MobileNetV2 *** gradient weighted class activation mapping algorithm to explain the model detection process and visually compare the detection results of each *** results indicate that the P,R,F1 values,mAP and FPS of the SSD_MobileNetV2+ECA model were higher than other models that introduced the attention ***,this model has less parameter with faster running speed,and is more suitable for detecting cotton diseases in complex environments,showing the best detection ***,the improved SSD_MobileNetV2+ECA model significantly enhanced the semantic information of the shallow feature map of the model,and has a goo

关键词： cotton disease detection SSD MobileNetV2 attention mechanism

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Visible-Light-Driven Four-Component Radical Relay Aminocarbonylation of Unactivated Alkenes

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Chinese Journal of Chemistry 2024年第9期42卷 990-996页

作者： Bin Lu feng-shuo Bao Zi-Wei He Wen-Jing Xiao Jia-Rong Chen Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction College of ChemistryCentralChina Normal University152 Luoyu RoadWuhanHubei 430079China Wuhan Institute of Photochemistry and Technology 7North Bingang RoadWuhanHubei 430083China Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province Gannan Normal UniversityGanzhouJiangxi 341000China

Catalytic four-component radical carbonylation of unactivated alkenes has recently been recognized as a robust protocol for rapid construction of various structurally diverse carbonyl *** the significance of fluorine-containing groups,this reaction class has been extensively applied to assembly of a variety of perfluoroalkyl carboxylic acid derivatives by transition metal ***,we report a visible-light-driven radical relay 1,2-perfluoroalkylation aminocarbonylation of unactivated alkenes using CO gas as carbonyl source and 4CzIPN as organic photocatalyst.A wide range of alkenes and amines were well tolerated,providing the valuableβ-perfluoroalkylated amides with generally good yields and high chemoselectivity.

关键词： Visible light Photoredox catalysis Radical aminocarbonylation Multicomponent reaction Carbon monoxide Unactivated alkenes AmidesIReactionmechanisms

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Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial

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Stroke & Vascular Neurology 2024年第1期9卷 75-81,I0047-I0052页

作者： Xiaoling Liao shuo feng Yicong Wang Yuesong Pan Weiqi Chen Hui Qu Xingquan Zhao Liping Liu Yongjun Wang Yilong Wang Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing TiantanHospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina National Center for Neurological Diseases BeijingChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina Beijing Laboratory of Oral Health Capital Medical UniversityBeijingChina

Background Perforating artery territorial infarction(PAI)caused by branch atheromatous disease(BAD)is prone to recurrence and early progression without an effective and well-documented antiplatelet treatment ***,an adjunctive antiplatelet agent,has shown great potential to treat acute ischaemic ***,whether the combination of tirofiban and aspirin can improve the prognosis of PAI remains *** To explore an effective and safe antiplatelet regimen for reducing the risk of recurrence and early neurological deterioration(END)in PAI caused by BAD by comparing the tirofiban and aspirin combination with placebo and aspirin *** Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction(STRATEGY)trial is an ongoing multicentre,randomised,placebo-controlled trial in *** patients shall be randomly assigned to receive standard aspirin with tirofiban or placebo on the first day and standard aspirin from days 2 to *** primary endpoint is a new stroke or END within 90 *** primary safety endpoint is severe or moderate bleeding within 90 *** The STRATEGY trial will assess whether tirofiban combined with aspirin is effective and safe in preventing recurrence and END in patients with *** registration number NCT05310968.

关键词： Aspirin regimen centre

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Evaluation of the Clinical Advantages of Laparoscopic Transverse Abdominal Wall Suspension in the Treatment of Pelvic Organ Prolapse

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Journal of Clinical and Nursing Research 2024年第4期8卷 197-202页

作者： Chao Wang shuo feng Department of Gynecology The Second Affiliated Hospital of Shandong Second Medical UniversityWeifang 261031China

Objective:To evaluate the clinical advantages of laparoscopic transverse abdominal wall suspension in treating pelvic organ ***:Sixty patients diagnosed with moderate to severe pelvic organ prolapse and underwent surgical treatment in our hospital between January 2022 and December 2023 were *** to different surgical methods,they were divided into an observation group(given laparoscopic transverse abdominal wall suspension)and a control group(given transvaginal mesh implantation),with 30 subjects/*** data on perioperative-related indicators,quality of life scores,postoperative recurrence,and complications of the two groups of patients were ***:The postoperative hospitalization days and intraoperative bleeding volume of the observation group were significantly lower than those of the control group,but had longer operation time than that of the control group(P0.05).Conclusion:Laparoscopic transverse abdominal wall suspension was more effective in treating pelvic organ prolapse and is an ideal surgical procedure.

关键词： Pelvic organ prolapse Laparoscopic transverse abdominal wall suspension Clinical advantages

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Differentiation and immunosuppressive function of CD19^(+)CD24^(hi)CD27^(+) regulatory B cells are regulated through the miR-29a-3p/NFAT5 pathway

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 472-480页

作者： Jin-Yang Li Tian-shuo feng Ji Gao Xin-Xiang Yang Xiang-Cheng Li Zhen-Hua Deng Yong-Xiang Xia Zheng-Shan Wu Hepatobiliary Center the First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Key Laboratory of Liver Transplantation Chinese Academy of Medical SciencesNanjing 210029China NHC Key Laboratory of Living Donor Liver Transplantation Nanjing Medical UniversityNanjing 210029China

Background: Regulatory B cells(Bregs) is an indispensable element in inducing immune tolerance after liver transplantation. As one of the microRNAs(miRNAs), mi R-29a-3p also inhibits translation by degrading the target mRNA, and yet the relationship between Bregs and mi R-29a-3p has not yet been fully explored. This study aimed to investigate the impact of miR-29a-3p on the regulation of differentiation and immunosuppressive functions of memory Bregs(m Bregs) and ultimately provide potentially effective therapies in inducing immune tolerance after liver transplantation. Methods: Flow cytometry was employed to determine the levels of Bregs in peripheral blood mononuclear cells. TaqMan low-density array miRNA assays were used to identify the expression of different miRNAs, electroporation transfection was used to induce mi R-29a-3p overexpression and knockdown, and dual luciferase reporter assay was used to verify the target gene of miR-29a-3p. Results: In patients experiencing acute rejection after liver transplantation, the proportions and immunosuppressive function of m Bregs in the circulating blood were significantly impaired. mi R-29a-3p was found to be a regulator of m Bregs differentiation. Inhibition of miR-29a-3p, which targeted nuclear factor of activated T cells 5(NFAT5), resulted in a conspicuous boost in the differentiation and immunosuppressive function of m Bregs. The inhibition of mi R-29a-3p in CD19~+ B cells was capable of raising the expression levels of NFAT5, thereby promoting B cells to differentiate into m Bregs. In addition, the observed enhancement of differentiation and immunosuppressive function of m Bregs upon mi R-29a-3p inhibition was abolished by the knockdown of NFAT5 in B cells. Conclusions: mi R-29a-3p was found to be a crucial regulator for m Bregs differentiation and immunosuppressive function. Silencing mi R-29a-3p could be a potentially effective therapeutic strategy for inducing immune tolerance after liver transplantation.

关键词： Regulatory B cells miR-29a-3p NFAT5 Liver transplantation

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论从史出,史论结合——程正民对俄苏文学理论的多维透视与历史重构

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学术研究 2024年第7期 24-32页

作者：丰硕赵勇北京师范大学文学院北京师范大学文艺学研究中心北京100875

程正民是中国当代重要的文艺理论家,其学术生涯主要围绕俄苏文学理论批评、俄苏马克思主义文论、文艺心理学及俄国作家创作心理学、20世纪俄罗斯诗学流派等主题展开深入探索。他的工作不仅填补了我国在俄苏文学理论领域的研究空白,更在... 详细信息

程正民是中国当代重要的文艺理论家,其学术生涯主要围绕俄苏文学理论批评、俄苏马克思主义文论、文艺心理学及俄国作家创作心理学、20世纪俄罗斯诗学流派等主题展开深入探索。他的工作不仅填补了我国在俄苏文学理论领域的研究空白,更在俄苏马克思主义文论、文艺心理学及巴赫金诗学研究方面做出了开创性的贡献。他对俄苏文学批评史的系统整理,以及在文艺心理学领域的开拓性工作,展现了其学术研究的深度与广度。他对巴赫金文化诗学的深刻理解,不仅体现在对“对话理论”的精准把握上,还体现在与中国文化诗学理念相结合后,为理解文学与社会历史文化的互动提供了独到的视角和深刻的理论阐释。此外,他还关注中国现代文学理论的发展,探讨文学创作实践和文学理论教材选取与编写的相关议题,为文艺学学科的发展与教学实践提供了某种参照。

关键词：程正民俄苏文学批评文艺心理学巴赫金文化诗学

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语义—语用接口上中国英语学习者对等级形容词的习得研究

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外国语 2024年第1期47卷 79-89页

作者：徐彤冯硕北京大学外国语学院北京100871

本文探究中国英语学习者对语义—语用接口上等级形容词的习得情况,以及伤面子语境如何影响形容词在否定句中的推导,旨在丰富对语义—语用接口上二语者语用推导能力的认识。本研究采用两个可接受性判断任务,结果发现二语者在无语境的情况... 详细信息

本文探究中国英语学习者对语义—语用接口上等级形容词的习得情况,以及伤面子语境如何影响形容词在否定句中的推导,旨在丰富对语义—语用接口上二语者语用推导能力的认识。本研究采用两个可接受性判断任务,结果发现二语者在无语境的情况下(实验一)表现出与母语者相同程度的否定语义加强和极性不对称性。然而,在伤面子语境中(实验二),二语者出现了与英语母语者不同的表现,且此表现很大程度上受到了伤面子因素的影响。本研究期望为语义—语用接口上的二语习得研究和二语者语用推导能力研究带来新的借鉴。

关键词：等级形容词否定语义加强极性不对称性语义—语用接口

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炭微球改性的丙烯酸酯吸油树脂的制备及其性能研究

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炭素技术 2024年第3期43卷 61-66页

作者：冯硕刘浩中海石油(中国)有限公司天津分公司工程技术作业中心天津300450 中航复合材料有限责任公司北京101300

为提升吸油树脂的吸油能力,引入新型炭微球对丙烯酸酯类树脂进行复合改性。以甲基丙烯酸异辛酯(EHMA)、聚丙烯酸十八烷基酯(SMA)为功能单体,苯乙烯(ST)为刚性单体,同时在悬浮聚合过程中引入炭微球成功制备了复合型吸油树脂。对合成的复... 详细信息

为提升吸油树脂的吸油能力,引入新型炭微球对丙烯酸酯类树脂进行复合改性。以甲基丙烯酸异辛酯(EHMA)、聚丙烯酸十八烷基酯(SMA)为功能单体,苯乙烯(ST)为刚性单体,同时在悬浮聚合过程中引入炭微球成功制备了复合型吸油树脂。对合成的复合吸油树脂进行结构测试和吸油性能表征。结果表明,复合吸油树脂中炭微球与树脂实现较好的复合,其吸油性能相较于不加炭微球得到明显提升。复合吸油树脂对柴油、煤油、汽油的饱和吸油率分别为18.214,17.421,5.124 g/g,较未复合吸油树脂分别提升了17.4%、25.1%、23.2%;对柴油、煤油、汽油的分离率分别为68.2%、95.6%、96.3%,并且具有良好的循环使用性,具有较好的应用前景。

关键词：丙烯酸酯炭微球吸油树脂悬浮聚合

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大模型驱动、人机协同的机器化学家云设施

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中国科学院院刊 2024年第1期39卷 41-49页

作者：崇媛媛冯硕王嵩江俊中国科学技术大学精准智能化学重点实验室合肥 230026

在当前由人工智能引发的科技浪潮中,化学科学研究面临着前所未有的机遇和挑战.为推动化学研究范式的变革,文章提出了机器化学家云设施的建设方案.该系统通过收集多通道数据构建数据库、发展化学知识增强的科学大模型、建设机器人设施集... 详细信息

在当前由人工智能引发的科技浪潮中,化学科学研究面临着前所未有的机遇和挑战.为推动化学研究范式的变革,文章提出了机器化学家云设施的建设方案.该系统通过收集多通道数据构建数据库、发展化学知识增强的科学大模型、建设机器人设施集群及搭建智能管理决策系统,践行科研新范式,大幅度提升科研效率,解决终端应用的科学问题.这一基础设施有望推动科研范式变革,在化学领域取得重大科学突破.

关键词：化学研究范式变革机器化学家云设施人工智能自动化实验人机协作

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语用容忍度视角下一语和二语等级含义的加工

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语言科学 2024年第1期23卷 59-70页

作者：冯硕魏一璞北京大学外国语学院北京100871 北京大学对外汉语教育学院北京100871

本项研究采用分级判断任务,从语用容忍度的角度出发,考察汉语为母语的英语学习者在二语(英语)和母语(汉语)中等级含义的生成,尤其是二语者对违反语用准则的信息不足句子的容忍度。实验结果表明,二语者并不具备明显的语用解读偏好——二... 详细信息

本项研究采用分级判断任务,从语用容忍度的角度出发,考察汉语为母语的英语学习者在二语(英语)和母语(汉语)中等级含义的生成,尤其是二语者对违反语用准则的信息不足句子的容忍度。实验结果表明,二语者并不具备明显的语用解读偏好——二语者在面对违反语用准则的句子时表现出与英语一语者同样的容忍度,而且二语者在其二语和母语中都表现出相似的容忍度。本研究旨在为关注语义-语用推导的相关研究提供实验设计方面的启示,期冀为二语等级含义研究引入新的研究视角。

关键词：语用容忍度等级含义一语加工二语加工

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