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Role of clinical data and multidetector computed tomography findings in acute superior mesenteric artery embolism

World Journal of Clinical Cases 2022年第13期10卷 4020-4032页

作者： Ju-shun yang Zhen-Yu Xu Fei-Xiang Chen Mei-Rong Wang Ruo-Chen Cong Xiao-Le Fan Bo-Sheng He Wei Xing Department of Radiology The Third Affiliated Hospital of Soochow UniversityChangzhou 213003Jiangsu ProvinceChina Department of Radiology The Second Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Ultrasonography The Second People's Hospital of NantongNantong 226002Jiangsu ProvinceChina

BACKGROUND Superior mesenteric artery embolism(SMAE)has acute onset and fast progression,which seriously threatens the life of *** computed tomography(MDCT)is one of the most important diagnostic methods for SMAE,which plays an important role in the diagnosis and prognosis of *** To evaluate the value of combined clinical data and MDCT findings in the diagnosis of acute SMAE and predict the risk factors for SMAE-related *** Data from 53 SMAE patients who received abdominal MDCT multi-phase enhancement and superior mesenteric artery digital subtraction angiography examinations were *** cox regression and multivariate cox model were used to analyze the correlation between death risk and clinical and computed tomography features in SMAE *** Univariate Cox regression model showed that intestinal wall thinning,intestinal wall pneumatosis,blood lactate>2.1 mmol/L and blood pH2.1 mmol/L(HR=5.26,95%CI:1.04-26.69,P=0.045)and intestinal wall thinning(HR=9.40,95%CI:1.05-83.46,P=0.044)were significantly increases the risk of death in patients with *** For patients with SAME,increased blood lactate and intestinal wall thinning are the risk factors for death;hence,close monitoring may reduce the mortality *** observation combined with MDCT signs can significantly improve SMAE diagnosis.

关键词： Multidetector computed tomography Superior mesenteric artery Embolization Blood lactate

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An ELISA Based on a Truncated Soluble ORF2 Protein for the Detection of PCV2 Antibodies in Domestic Pigs

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Virologica Sinica 2010年第3期25卷 191-198页

作者： Shuang-hui YIN shun-li yang Hong TIAN Jin-yan WU You-jun SHANG Xue-peng CAI Xiang-tao LIU Lanzhou Veterinary Research Institute Chinese Academy of Agricultural Sciences State Key Laboratory of Veterinary Etiological Biology Key Laboratory of Animal Virology of Ministry of Agriculture Lanzhou 730046China

Postweaning multisystemic wasting syndrome (PMWS) is an important swine disease that is closely associated with porcine circovirus type 2 (PCV2). The capsid protein (Cap protein) is a major structural protein that has at least three immunoreactive regions, and it can be a suitable candidate antigen for detecting the specific antibodies of a PCV2 infection. In the present study, an indirect enzyme-linked immunosorbent assay (TcELISA) based on a truncated soluble Cap protein produced in Escherichia coli (***) was established and validated for the diagnostic PCV2 antibodies in swine. The TcELISA was validated by comparison with an indirect immunofluorescence assay (IIFA). The diagnostic sensitivity (DSN), specificity (DSP), and accuracy of the TcELISA were 88.6%, 90.7% and 89.4%, respectively. The agreement rate was 89.38% between results obtained with TcELISA and IIFA on 113 field sera. A cross-reactivity assay showed that the method was PCV2-specific by comparison with other sera of viral disease. Therefore ,the TcELISA will be helpful for the development of a reliable serology diagnostic test for large scale detection of PCV2 antibodies and for the evaluation of vaccine against PCV2 in swine.

关键词： Porcine circovirus type 2 (PCV2) Soluble ORF2 protein ELISA Antibody detection

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High expression of type I inositol 1,4,5-trisphosphate receptor in the kidney of rats with hepatorenal syndrome

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World Journal of Gastroenterology 2018年第29期24卷 3273-3280页

作者： Jing-Bo Wang Ye Gu Ming-Xiang Zhang shun yang Yan Wang Wei Wang Xi-Ran Li Yi-Tong Zhao Hai-Tao Wang Liver Cirrhosis Ward the Sixth People’s Hospital of ShenyangShenyang 110006Liaoning ProvinceChina Liaoning Cancer Hospital&Institute Shenyang 110042Liaoning ProvinceChina Department of General Surgery the Second Affiliated Hospital of Shenyang Medical CollegeShenyang 110002Liaoning ProvinceChina

AIM To detect the expression of typeⅠ inositol 1,4,5-trisphosphate receptor(IP3 RI) in the kidney of rats with hepatorenal syndrome(HRS).METHODS One hundred and twenty-five Sprague-Dawley rats were randomly divided into four groups to receive an intravenous injection of D-galactosamine(D-Gal N) plus lipopolysaccharide(LPS; group G/L, n = 50), D-Gal N alone(group G, n = 25), LPS alone(group L, n = 25), and normal saline(group NS, n = 25), *** 3, 6, 9, 12, and 24 h after injection, blood, liver, and kidney samples were collected. Hematoxylineosin staining of liver tissue was performed to assess hepatocyte necrosis. Electron microscopy was used to observe ultrastructural changes in the kidney. Western blot analysis and real-time PCR were performed to detect the expression of IP3 RI protein and m RNA in the kidney, *** Hepatocyte necrosis was aggravated gradually, which was most significant at 12 h after treatment with D-galactosamine/lipopolysaccharide, and was characterized by massive hepatocyte necrosis. At the same time, serum levels of biochemical indicators including liver and kidney function indexes were all significantly changed. The structure of the renal glomerulus and tubules was normal at all time points. Western blot analysis indicated that IP3 RI protein expression began to rise at 3 h(P < 0.05) and peaked at 12 h(P < 0.01). Real-time PCR demonstrated that IP3 RI m RNA expression began to rise at 3 h(P < 0.05) and peaked at 9 h(P < 0.01).CONCLUSION IP3 RI protein expression is increased in the kidney of HRS rats, and may be regulated at the transcriptional level.

关键词： Hepatorenal syndrome TypeⅠ inositol 1,4,5-trisphosphate receptor Glomerular mesangial cells Vascular smooth muscle cells

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The Recognition of Fault Type of Transmission Line Based on Wavelet Transmission and FNN

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通讯和计算机（中英文版） 2013年第5期10卷 724-729页

作者： Li-Zhang shun Ling-Chen Qiao Zhi-Wang shun-Lv yang He-Liu Department of Science Siehuan University of Science and Engineering Zigong 643000 China

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创新与核心能力体系研究

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西北大学学报（哲学社会科学版） 2006年第5期36卷 61-64页

作者：杨顺吉林大学商学院吉林长春130021

创新是企业经营要素的新组合。企业核心能力是企业发展能力中最重要的能力,它源于企业创新。企业创新点,实质在企业价值的“链环”上,企业核心能力的形成,关键在于建立价值链某个环节上的竞争优势,企业应当通过创新培育核心能力体系。... 详细信息

创新是企业经营要素的新组合。企业核心能力是企业发展能力中最重要的能力,它源于企业创新。企业创新点,实质在企业价值的“链环”上,企业核心能力的形成,关键在于建立价值链某个环节上的竞争优势,企业应当通过创新培育核心能力体系。而创新必须要有卓越的创意设计、科学的策划和有效的策略。

关键词：企业创新核心能力经营要素

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Retinal nerve fiber layer in primary open-angle glaucoma with high myopia determined by optical coherence tomography and scanning laser polarimetry

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Chinese Medical Journal 2013年第8期126卷 1425-1429页

作者： WANG Xiao-en WANG Xiao-yu GU yang-shun HUANG Zhu Center of GlaucomaDepartment of Ophthalmology theFirst Affiliated Hospital College of Medicine Zhejiang UniversityHangzhou Zhejiang 310003 China Centerof Visual SciencesDepartment of Ophthalmology theFirst Affiliated Hospital College of Medicine Zhejiang UniversityHangzhou Zhejiang 310003 China

Background Fundus changes associated with high myopia （HM） may mask those associated with primary open-angle glaucoma （POAG）. This study aim to determine the characteristics of RNFL thickness changes in patients with both POAG and HM and compare these to changes in patients with only HM. The diagnostic capabilities of both OCT and GDxVCC in this subset of patients are also evaluated. Methods Twenty-two eyes with POAG and HM （spherical equivalent （SE） between -6.0 and -12.0 D） were evaluated, and 22 eyes with HM were used for comparison. Characteristic retinal nerve fiber layer （RNFL） thickness profiles in patients with POAG and HM were examined using optical coherence tomography （OCT） and scanning laser polarimetry with variable corneal compensation （GDxVCC）, and the diagnostic capabilities of these imaging modalities were compared. RNFL parameters evaluated included superior average （Savg-GDx）, inferior average （lavg-GDx）, temporal-superior-nasal- inferior-temporal （TSNIT） average, and nerve fiber indicator （NFI） on GDxVCC and superior average （Savg-OCT）, inferior average （lavg-OCT）, nasal average （Navg-OCT）, temporal average （Tavg-OCT）, and average thickness （AvgThick-OCT） on OCT （fast RNFL scan）. Visual field testing was performed and defects were evaluated using mean defect （MD） and pattern standard deviation （PSD）. Results The RNFL parameters （P 〈0.05） significantly different between groups included Savg-GDx, lavg-GDx, TSNIT average, NFI, Savg-OCT, lavg-OCT, Tavg-OCT, and AvgThick-OCT. Significant correlations existed between TSNIT average and AvgThick-OCT （r=0.778）, TSNIT average and MD （r=0.749）, AvgThick-OCT and MD （r=0.647）, TSNIT average and PSD （r=-0.756）, and AvgThick-OCT and PSD （r=-0.784）. The area under the receiver operating characteristic curve （AUROC） values of TSNIT average, Savg-GDx, lavg-GDx, NFI, Savg-OCT, lavg-OCT, Navg-OCT, Tavg-OCT, and AvgThick-OCT were 0.947, 0.962, 0.973, 0.994, 0.909, 0.917, 0.511, 0.906, and 0.913, respectively. The NFI

关键词： high myopia, primary open-angle glaucoma, optical coherenee tomography scanning laser polarimetry

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Optimal Sliding Mode Recruitment Schemes of Enterprise Knowledge Workers System

Optimal Sliding Mode Recruitment Schemes of Enterprise Knowl...

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第40届中国控制会议

作者： yang-shun Ma Bao-Lin Zhang Yu-Xiang yang College of Economics and Management China Jiliang University College of Science China Jiliang University

This paper deals with the recruitment schemes of enterprise knowledge workers system based on the optimal sliding mode control ***,by considering job-transfer,natural resignation,voluntary resignation,promotion,recruitment and dismissal,the enterprise knowledge workers system can be modeled as a dynamic nonlinear uncertain ***,by using the optimal sliding mode control method,the design method of the optimal sliding mode control law for the system is *** condition for the asymptotic stability of the sliding mode manifold is proposed,and it is proved that under such a control law,the state of the enterprise knowledge workers system can reach the sliding surface in a finite *** results show that the optimal sliding mode control law（recruitment schemes） proposed in this paper can make enterprise knowledge workers system asymptotically ***,under the presented control law,the system is robust to parameter perturbation.

关键词： Knowledge workers Sliding mode control Optimal control Recruitment Stability

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Analysis of spontaneous, gamma ray-and ethylnitrosourea-induced hprt mutants in HL-60 cells with multiplex PCR

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World Journal of Gastroenterology 2003年第3期9卷 578-583页

作者： Sheng-Xue Liu Jia Cao Hui An Hua-Min shun Lu-Jun yang Yong Liu Department of Health Toxicology,Preventive Medical College,Third Military Medical University,Chongqing 400038,China Department of Healath Toxicology Preventive Medical College Third Military Medical University Chongqing 400038 China.

AIM: To explore the molecular spectra and mechanism of human hypoxanthine guanine phosphoribosyl transferase (hprt) gene mutation induced by ethyluitrosourea (ENU) and 60Co γ-***: Independent human promyelocytic leukemia cells (HL-60) mutants at the hprt locus were isolated from untreated, ethyluitrosourea (ENU) and 60Co γ-ray-exposed cells, respectively, and verified by two-way screening. The genetic changes underlying the mutation were determined by multiplex polymerase chain reaction (PCR) amplification and electrophoresis ***: With dosage increased, survival rate of plated cell reduced (in the group with dosage of ENU with 100-200μg/ml, P＜0.01; in the group with dosage of 60Co γ-ray with 2-4 Gy, P＜0.05) and mutational frequency increased (in the group of ENU 12.5-200.0 μg/ml, P＜0.05; in the group of 60Co γ-ray with 1-4 Gy, P＜0.05) significantly. In the 13spontaneous mutants analyzed, 92.3 % of mutant clones did not show any change in number or size of exon, a single exon was lost in 7.7 %, and no evidence indicated total gene deletion occurred in nine hprt exons. However, deletions were found in 79.7 % of ENU-induced mutations (62.5-89.4 %,P＜0.01) and in 61.7 % of gamma-ray-induced mutations (28.6-76.5 %, P＜0.01). There were deletion mutations in all 9 exons of hprt gene and the most of induced mutations were chain deletion with multiplex exons (97.9 % in gammaray-induced mutants, 88.1% in ENU-induced mutants).CONCLUSION: The spectra of spontaneous mutations differs completely from that induced by EUN or 60Co γ-*** both ENU and γ-ray can cause destruction of genetic structure, mechanism of mutagenesis between them may be different.

关键词：人次黄嘌呤鸟嘌呤转磷酸糖基酶 HL-60细胞 γ射线多重PCR 基因突变分子生物学

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COVID-19 and liver dysfunction:What nutritionists need to know

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World Journal of Gastroenterology 2022年第15期28卷 1526-1535页

作者： Ming-Ke Wang Xue-Lu Yu Li-Yun Zhou Hong-Mei Si Ju-Fen Hui Deng-Yong Hou Wei-Peng Li Ji-shun yang Department of Disease Control and Prevention Naval Medical Center of PLANaval Medical UniversityShanghai 200052China Medical Care Center Naval Medical Center of PLANaval Medical UniversityShanghai 200052China

The coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2 has brought serious challenges for the medical *** with COVID-19 usually have respiratory ***,liver dysfunction is not an uncommon ***,the degree of liver dysfunction is associated with the severity and prognosis of ***,diagnosis,and treatment of malnutrition should be routinely recommended in the management of patients with COVID-19,especially in those with liver ***,a large number of studies have reported that nutrition therapy measures,including natural dietary supplements,vitamins,minerals and trace elements,and probiotics,might have potential hepatoprotective effects against COVID-19-related liver dysfunction via their antioxidant,antiviral,anti-inflammatory,and positive immunomodulatory *** review mainly focuses on the possible relationship between COVID-19 and liver dysfunction,nutritional and metabolic characteristics,nutritional status assessment,and nutrition therapy to provide a reference for the nutritionists while making evidence-based nutritional decisions during the COVID-19 pandemic.

关键词： COVID-19 SARS-CoV-2 Liver dysfunction Nutritional status assessment Nutrition therapy

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THE UNITED METHOD FOR THE CALCULATION OF SEEPAGE CONTROL BY ADOPTING WEIGHTING SOIL LAYER ON THE BACK SIDE OF DIKE

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Journal of Hydrodynamics 2001年第4期13卷 92-97页

作者： Liu Chuan-shun, yang Jin-zhong College of Water Conservancy and Hydropower Engineering, Wuhan University, Wuhan 430072, China College of Water Conservancy and Hydropower Engineering Wuhan University

Constructing a weighting soil layer at the downstream toe of dike on layered ground is an effective measure to prevent the foundation from blowout failures. In this paper, a series of differential equations describing the seepage flow in layered dike foundation were established, and a united method combining analytic method with one-dimensional finite difference method was proposed for solving the equations. The case study shows that the results calculated by the united method are considerably identical to the computational results of Finite Element Method (FEM), and the united method is very simple and easy compared to the FEM.

关键词： dike weighting soil layer seepage calculation seepage control united method

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