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Expert consensus on irrigation and intracanal medication in root canal therapy

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International Journal of Oral Science 2024年第1期16卷 26-35页

作者： Xiaoying Zou Xin Zheng Yuhong Liang Chengfei Zhang Bing Fan Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Zhi Chen Xi Wei Lihong Qiu Wenxia Chen Wenxi He Xin Xu Liuyan Meng Chen Zhang Liming Chen shuli deng Yayan Lei Xiaoli Xie Xiaoyan Wang Jinhua Yu Jin Zhao Song Shen Xuedong Zhou Lin Yue Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Center of Stomatology Peking University HospitalBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina Department of Emergency Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Restorative Dental Sciences EndodonticsFaculty of DentistryThe University of Hong KongPok Fu LamHong Kong SARChina State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool&Hospital of StomatologyWuhan UniversityWuhanChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghua School of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina State Key Laboratory of Oral&Maxillofacial Reconstruction and R

Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes.

关键词： treatment irrigation Expert

Expert consensus on difficulty assessment of endodontic therapy

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International Journal of Oral Science 2024年第1期16卷 15-25页

作者： Dingming Huang Xiaoyan Wang Jingping Liang Junqi Ling Zhuan Bian Qing Yu Benxiang Hou Xinmei Chen Jiyao Li Ling Ye Lei Cheng Xin Xu Tao Hu Hongkun Wu Bin Guo Qin Su Zhi Chen Lihong Qiu Wenxia Chen Xi Wei Zhengwei Huang Jinhua Yu Zhengmei Lin Qi Zhang Deqin Yang Jin Zhao Shuang Pan Jian Yang Jiayuan Wu Yihuai Pan Xiaoli Xie shuli deng Xiaojing Huang Lan Zhang Lin Yue Xuedong Zhou State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Operative Dentistry and Endodontics West China Hospital of StomatologySichuan UniversityChengduChina Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijingChina Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Clinical Research Center for Oral DiseasesNational Center for StomatologyShanghai Key Laboratory of StomatologyShanghaiChina Department of Operative Dentistry and Endodontics Hospital of StomatologyGuanghuaSchool of StomatologySun Yat-Sen University&Guangdong Provincial Key Laboratory of StomatologyGuangzhouChina The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of StomatologyWuhan UniversityWuhanChina Department of Operative Dentistry&Endodontics School of StomatologyThe Fourth Military Medical UniversityXi’anChina Department of Endodontics Beijing Stomatological HospitalSchool of StomatologyCapital Medical UniversityBeijingChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Preventive Dentistry West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Geriatric dentistry West China Hospital of Stomatology

Endodontic diseases are a kind of chronic infectious oral disease. Common endodontic treatment concepts are based on the removal of inflamed or necrotic pulp tissue and the replacement by gutta-percha. However, it is very essential for endodontic treatment to debride the root canal system and prevent the root canal system from bacterial reinfection after root canal therapy(RCT). Recent research, encompassing bacterial etiology and advanced imaging techniques, contributes to our understanding of the root canal system’s anatomy intricacies and the technique sensitivity of RCT. Success in RCT hinges on factors like patients, infection severity, root canal anatomy, and treatment techniques. Therefore, improving disease management is a key issue to combat endodontic diseases and cure periapical lesions. The clinical difficulty assessment system of RCT is established based on patient conditions, tooth conditions, root canal configuration, and root canal needing retreatment, and emphasizes pre-treatment risk assessment for optimal outcomes. The findings suggest that the presence of risk factors may correlate with the challenge of achieving the high standard required for RCT. These insights contribute not only to improve education but also aid practitioners in treatment planning and referral decision-making within the field of endodontics.

关键词： anatomy difficulty treatment

乳酸链球菌素和氟化钠对变异链球菌的协同作用研究

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实用口腔医学杂志 2024年第5期40卷 625-630页

作者：滕健赢石雨杉吴思佳汪飒王媛邓淑丽王慧明浙江大学口腔医学院杭州310016 浙江大学医学院附属口腔医院浙江省口腔生物医学研究重点实验室

目的:研究乳酸链球菌素(Nisin)与氟化钠(NaF)联合应用对变异链球菌(***)的影响。方法:采用微量肉汤法测量Nisin与NaF对变异链球菌的最小抑菌浓度(MIC),利用棋盘法计算分级抑菌浓度指数(FIC)。将同一MIC浓度的NaF和Nisin复配成NF,测量NF... 详细信息

目的:研究乳酸链球菌素(Nisin)与氟化钠(NaF)联合应用对变异链球菌(***)的影响。方法:采用微量肉汤法测量Nisin与NaF对变异链球菌的最小抑菌浓度(MIC),利用棋盘法计算分级抑菌浓度指数(FIC)。将同一MIC浓度的NaF和Nisin复配成NF,测量NF对变异链球菌产酸和耐酸的抑制效果。采用结晶紫染色测定NF抑制生物膜形成的能力,以及对已形成生物膜的破坏和分散作用,激光共聚焦显微镜观察生物膜结构变化。结果:NaF和Nisin的MIC分别为0.6 mg/mL和20 mg/mL,两者的FIC为0.75。1/8×MIC的NF对产酸和生物膜形成的抑制显著高于1/4×MIC的NaF和Nisin(P<0.05),对已形成的生物膜无分散作用。1/2×MIC NF可以比1×MIC的NaF和Nisin更显著地破坏生物膜内变异链球菌的耐酸性。2×MIC浓度下,NF、NaF、Nisin对已形成的生物膜结构造无明显破坏。结论:Nisin和NaF对变异链球菌的增殖以及产酸、耐酸和生物膜形成具有协同的抑制作用。

关键词：乳酸链球菌素氟化钠变异链球菌

High-throughput sequencing identifies salivary microbiota in Chinese caries-free preschool children with primary dentition

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2021年第4期22卷 285-294页

作者： Lei XU Zhifang WU Yuan WANG Sa WANG Chang SHU Zhuhui DUAN shuli deng The Affiliated Hospital of Stomatology School of StomatologyZhejiang University School of Medicineand Key Laboratory of Oral Biomedical Research of Zhejiang ProvinceHangzhou 310006China Department of Stomatology Luoyang Central Hospital Affiliated to Zhengzhou UniversityLuoyang 471009China

Objectives:The study aimed at identifying salivary microbiota in caries-free Chinese preschool children using highthroughput ***:Saliva samples were obtained from 35 caries-free preschool children(18 boys and 17 girls)with primary dentition,and 16 S ribosomal DNA(r DNA)V3–V4 hypervariable regions of the microorganisms were analyzed using Illumina ***:At 97%similarity level,all of these reads were clustered into 334 operational taxonomic units(OTUs).Among these,five phyla(Firmicutes,Proteobacteria,Actinobacteria,Bacteroidetes,and Candidate division TM7)and13 genera(Streptococcus,Rothia,Granulicatella,Prevotella,Enterobacter,Veillonella,Neisseria,Staphylococcus,Janthinobacterium,Pseudomonas,Brevundimonas,Devosia,and Gemella)were the most dominant,constituting 99.4%and 89.9%of the salivary microbiota,*** core salivary microbiome comprised nine genera(Actinomyces,Capnocytophaga,Gemella,Granulicatella,Lachnoanaerobaculum,Neisseria,Porphyromonas,Rothia,and Streptococcus).Analysis of microbial diversity and community structure revealed a similar pattern between male and female *** difference in microbial community composition between them was mainly attributed to Neisseria(P=0.023).Furthermore,functional prediction revealed that the most abundant genes were related to amino acid transport and ***:Our results revealed the diversity and composition of salivary microbiota in caries-free preschool children,with little difference between male and female *** of the core microbiome,coupled with prediction of gene function,deepens our understanding of oral microbiota in cariesfree populations and provides basic information for associating salivary microecology and oral health.

关键词： Salivary microbiota Caries-free Preschool children Primary dentition Illumina MiSeq 16S rDNA V3-V4 hypervariable regions

Break of thermal equilibrium between optical and acoustic phonon branches of CsPbI_(3)under continuous-wave light excitation and cryogenic temperature

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Chinese Chemical Letters 2024年第7期35卷 534-537页

作者： Rongliang deng Yihang Chen Xiaotong Fan Guolong Chen shuli Wang Changzhi Yu Xiao Yang Tingzhu Wu Zhong Chen Yue Lin Department of Electronic Science Fujian Engineering Research Center for Solid-State LightingXiamen UniversityXiamen 361005China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China Institute of Electromagnetics and Acoustics School of Electronic Science and EngineeringXiamen UniversityXiamen 361005China

The kinetic of low-temperature carrier and lattice of lead-halide perovskite is yet to be fully *** this work,we investigate the steady-state photoluminescences(PLs)of CsPbI_(3)at the environmental temperature(Te)ranging from 20 K to 300 K,and observed anomalous behaviors at cryogenic temperatures:The carrier temperature(Tc)of pure CsPbI_(3)exhibits a negative correlation with Te,accompanied by an expansion in Urbach tails of absorption spectra(Abs.)and excessive red-shifts at peak energy of *** phenomena are also observed in those samples containing a certain amount of Cs_(4)PbI_(6),but to a lesser extent and occurs at lower *** is attributed to the intensified hot phonon bottleneck effect(HPB)in CsPbI_(3)at cryogenic Te,which hinders the energy transfer from hot carriers,via longitudinal optics(LO)phonons to longitudinal acoustic(LA)phonons,to the *** samples under continuous-wave laser excitation,in specific,the barrier induced by the enhanced HPB at low Teprevents the effective thermalization among carriers,LO and LA phonons,which,therefore,form thermally isolated ensembles with different *** cryogenic Terange,the elevated temperatures of carrier and LO phonon expand the high-energy side of PLs and the low-energy tail of Abs.,*** those samples in which the CsPbI_(3)is mixed with Cs_(4)PbI_(6),the interfacial LO-LO interaction across them provides a bypass for heat dissipation,mitigating the heat accumulation in LO-phonons of CsPbI_(3).The results suggest that a strong HPB effect may break the thermal equilibrium among different branches of phonons in the lattice under certain extreme conditions.

关键词： CsPbI_(3) Cs_(4)PbI_(6) Low-temperature carrier Lattice kinetic Hot phonon bottleneck effect Interfacial LO-LO interaction

Expert consensus on early childhood caries management

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International Journal of Oral Science 2022年第3期14卷 231-244页

作者： Jing Zou Qin Du Lihong Ge Jun Wang Xiaojing Wang Yuqing Li Guangtai Song Wei Zhao Xu Chen Beizhan Jiang Yufeng Mei Yang Huang shuli deng Hongmei Zhang Yanhong Li Xuedong Zhou State Key Laboratory of Oral Diseases&National Clinical Research Centre for Oral Diseases&Department of Pediatric Dentistry West China Hospital of StomatologySichuan UniversityChengduChina Department of Stomatology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduChina Department of Pediatric Dentistry Peking University School and Hospital of StomatologyBeijingChina Ninth People’s Hospital School of MedicineShanghai Jiao Tong UniversityDepartment of Pediatric DentistryShanghai Key Laboratory of StomatologyShanghaiChina State Key Laboratory of Military Stomatology National Clinical Research Center for Oral DiseasesShanxi Key Laboratory of Military StomatologyDepartment of Pediatric DentistrySchool of StomatologyFourth Military Medical UniversityXi’anChina State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases West China School of StomatologySichuan UniversityChengduChina Department of Pediatric Dentistry School and Hospital of StomatologyWuhan UniversityWuhanChina Department of Pediatric Dentistry Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat‑Sen UniversityGuangzhouChina Department of Pediatric Dentistry School and Hospital of StomatologyChina Medical UniversityShenyangChina Department of Pediatric Dentistry School and Hospital of StomatologyTongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghaiChina Department of Pediatric Dentistry Affiliated Stomatological HospitalNanjing Medical UniversityNanjingChina Department of Pediatric Dentistry Hospital of StomatologyJilin UniversityChangchunChina The Affiliated Hospital of Stomatology School of StomatologyZhejiang University School of Medicineand Key Laboratory of Oral Biomedical Research of Zhejiang ProvinceHangzhouChina Department of Pediatric Dentistry The Affiliated Stomatological Hospital of Chongqing Medical UniversityChongqing Key Laboratory of Or

Early childhood caries(ECC)is a significant chronic disease of childhood and a rising public health burden *** may cause a higher risk of new caries lesions in both primary and permanent dentition,affecting lifelong oral *** occurrence of ECC has been closely related to the core microbiome change in the oral cavity,which may be influenced by diet habits,oral health management,fluoride use,and dental ***,it is essential to improve parental oral health and awareness of health care,to establish a dental home at the early stage of childhood,and make an individualized caries management *** interventions according to the minimally invasive concept should be carried out to treat dental *** expert consensus mainly discusses the etiology of ECC,caries-risk assessment of children,prevention and treatment plan of ECC,aiming to achieve lifelong oral health.

关键词： ECC Expert consensus on early childhood caries management

Saturation Estimation with Complex Electrical Conductivity for Hydrate-Bearing Clayey Sediments:An Experimental Study

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Journal of Ocean University of China 2024年第1期23卷 173-189页

作者： XING Lanchang ZHANG shuli ZHANG Huanhuan WU Chenyutong WANG Bin LAO Liyun WEI Wei HAN Weifeng WEI Zhoutuo GE Xinmin deng Shaogui College of Control Science and Engineering China University of Petroleum(East China)Qingdao 266580China School of Water Energy and EnvironmentCranfield UniversityCranfield MK430ALUnited Kingdom Department of Alternative Energy PetroChina Research Institute of Petroleum Exploration&DevelopmentLangfang 065007China School of Geosciences China University of Petroleum(East China)Qingdao 266580China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China

Clays have considerable influence on the electrical properties of hydrate-bearing *** is desirable to understand the electrical properties of hydrate-bearing clayey sediments and to build hydrate saturation(S_(h))models for reservoir evaluation and *** electrical properties of tetrahydrofuran-hydrate-bearing sediments with montmorillonite are characterized by complex conductivity at frequencies from 0.01 Hz to 1 *** effects of clay and Sh on the complex conductivity were analyzed.A decrease and increase in electrical conductance result from the clay-swelling-induced blockage and ion migration in the electrical double layer(EDL),*** quadrature conductivity increases with the clay content up to 10%because of the increased surface site density of counterions in *** the in-phase conductivity and quadrature conductivity decrease consistently with increasing Sh from 0.50 to *** sets of models for Sh evaluation were *** model based on the Simandoux equation outperforms Archie’s formula,with a root-mean-square error(E_(RMS))of 1.8%and 3.9%,respectively,highlighting the clay effects on the in-phase *** fre-quency effect correlations based on in-phase and quadrature conductivities exhibit inferior performance(E_(RMS)=11.6%and 13.2%,re-spectively)due to the challenge of choosing an appropriate pair of frequencies and intrinsic uncertainties from two *** second-order Cole-Cole formula can be used to fit the complex-conductivity *** pair of inverted Cole-Cole parameters,i.e.,characteristic time and chargeability,is employed to predict S_(h) with an E_(RMS) of 5.05%and 9.05%,respectively.

关键词： gas hydrate complex electrical conductivity hydrate-bearing clayey sediment hydrate saturation Simandoux equation frequency dispersion Cole-Cole formula

Modulation of charge in C_(9)N_(4) monolayer for a highcapacity hydrogen storage as a switchable strategy

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Frontiers of physics 2024年第4期19卷 47-55页

作者： Lin Ju Junxian Liu Minghui Wang Shenbo Yang shuli Liu School of Physics and Electric Engineering Anyang Normal UniversityAnyang 455000China School of Mechanical Medical and Process EngineeringQueensland University of TechnologyBrisbane QLD 4001Australia Hongzhiwei Technology(Shanghai)Co.Ltd. 1599 Xinjinqiao RoadPudongShanghai 201206China

Developing advanced hydrogen storage materials with high capacity and efficient reversibility is a crucial aspect for utilizing hydrogen source as a promising alternate to fossil *** this paper,we have systematically investigated the hydrogen storage properties of neutral and negatively charged C_(9)N_(4) monolayer based on density functional theory(DFT).Our foundings indicate that injecting additional electrons into the adsorbent significantly boosts the adsorption capacity of C_(9)N_(4) monolayer to H2 *** gravimetric density of negatively charged C_(9)N_(4) monolayer can reach up to 10.80 wt% when fully covered with *** other hydrogen storage methods,the storage and release processes happen automatically upon introducing or removing extra ***,these operations can be easily adjusted through activating or deactivating the charging *** a result,the method is easily reversible and has tunable kinetics without requiring particular ***,C_(9)N_(4) is proved to be a suitable candidate for efficient electron injection/release due to its well electrical *** work can serve as a valuable guide in the quest for a novel category of materials for hydrogen storage with high capacity.

关键词： hydrogen storage C_(9)N_(4)monolayer charge modulation density functional theory

Phase and chemical state tuning of FeNi oxides for oxygen evolution reaction

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Science China Chemistry 2024年第8期67卷 2755-2766页

作者： Jiawei Wu Zhouyang Ma Lice Yu shuli Wang Fulin Yang Ligang Feng School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China

Advancing and deploying the Fe Ni-based catalyst,the state-of-the-art pre-electrocatalysts,for oxygen evolution reactions(OER)still suffer from unclear chemical state correlation to the catalytic ability,as evidenced by the variedly reported performance for the different Fe Ni ***,we contributed the phase and redox chemical states tuning of Fe Ni oxides by the surface microenvironment regulation for the OER catalysis that was realized by the urea-assisted pyrolysis and molybdenum-doping technique by integrating molybdenum into the iron–nickel metal-organic *** by the complicated and compromised atmosphere,namely,the oxidation state driven by the Mo doping and reduction ability induced by the urea-assisted pyrolysis,could transfer confined Fe Ni oxides to hybrid phases of Fe_(2)O_(3)and FeNi_(3)alloy,and the resultant compromised chemical states by the charge redistribution imparted very high electrocatalytic performance for OER compared with the control *** insitu Raman spectroscopy and post-XPS analysis confirmed the facile Fe/Ni oxyhydroxide active phase formation resulting from the proper phase and chemical states,and theoretical analysis disclosed the microenvironment regulation resulting in the charge redistribution forming the electron accumulation and depletion sites to accelerate the oxygen-species to oxyhydroxide-species transformation and enhance the electronic state density near the Fermi level by significantly reducing the energy *** work not only showed the importance of surface chemical state tunning that can basically answer the varied performance of Fe Ni catalysts but also revealed an effective approach for fine-tuning their catalytic properties.

关键词： oxygen evolution reaction FeNi-based catalysts urea pyrolysis chemical states charge redistribution