检索结果-南通市图书馆

Binary Hybrid Artificial Hummingbird with Flower Pollination Algorithm for Feature Selection in Parkinson’s Disease Diagnosis

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2024年第2期21卷 1003-1021页

作者： Liuyan Feng Yongquan zhou Qifang Luo College of Artificial Intelligence Guangxi University for NationalitiesNanning530006China Xiangsihu College of Guangxi University for Nationalities Nanning532100GuangxiChina Guangxi Key Laboratories of Hybrid Computation and IC Design Analysis Nanning530006China

Parkinson’s disease is a neurodegenerative disorder that inflicts irreversible damage on *** experimental data regarding Parkinson’s patients are redundant and irrelevant,posing significant challenges for disease ***,there is a need to devise an effective method for the selective extraction of disease-specific information,ensuring both accuracy and the utilization of fewer *** this paper,a Binary Hybrid Artificial Hummingbird and Flower Pollination Algorithm(FPA),called BFAHA,is proposed to solve the problem of Parkinson’s disease diagnosis based on speech ***,combining FPA with Artificial Hummingbird Algorithm(AHA)can take advantage of the strong global exploration ability possessed by FPA to improve the disadvantages of AHA,such as premature convergence and easy falling into local ***,the Hemming distance is used to determine the difference between the other individuals in the population and the optimal individual after each iteration,if the difference is too significant,the cross-mutation strategy in the genetic algorithm(GA)is used to induce the population individuals to keep approaching the optimal individual in the random search process to speed up finding the optimal ***,an S-shaped function converts the improved algorithm into a binary version to suit the characteristics of the feature selection(FS)*** this paper,10 high-dimensional datasets from UCI and the ASU are used to test the performance of BFAHA and apply it to Parkinson’s disease *** with other state-of-the-art algorithms,BFAHA shows excellent competitiveness in both the test datasets and the classification problem,indicating that the algorithm proposed in this study has apparent advantages in the field of feature selection.

关键词： Artificial Hummingbird Algorithm Flower pollination algorithm Feature selection Parkinson’s disease Meta-heuristic

The role of proteasomes in tumorigenesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第4期11卷 155-169页

作者： Xiangyi zhou Ruqing Xu Yue Wu Li zhou Tingxiu Xiang Department of Oncology The First Affliated Hospital of Chongqing Medical UniversityChongqing 400016China Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Chongqing University Cancer HospitalChongqing 400030China

Protein homeostasis is the basis of normal life activities,and the proteasomefamily plays an extremely important function in this *** proteasome 2os is a concentric circle structure with twoαrings and twoβrings *** proteasome 2os can perform both ATP-dependent and non-ATP-dependent ubiquitination proteasome degradation by binding to various subunits(such as 19S,11S,and 200 PA),which is performed by its active subunitβ1,β2,andβ*** proteasome can degrade misfolded,excess proteins tomaintain *** the same time,it can be utilized by tumors to degrade over-proliferate and unwanted proteins to support their *** can affect the development of tumors from several aspects including tumor signaling pathways such as NF-kB and p53,cell cycle,immune regulation,and drug ***-encoding genes have been found to be overexpressed in a variety of tumors,providing a potential novel target for cancer *** addition,proteasome inhibitors such as bortezomib,carfilzomib,and ixazomib have been put into clinical application as the first-line treatment of multiple *** and more studies have shown that it also has different therapeutic effects in other tumors such as hepatocellular carcinoma,non-small cell lung cancer,glioblastoma,and ***,proteasome inhibitors are not much effective due to their tolerance and singleness in other ***,further studies on their mechanisms of action and drug interactions are needed to investigate their therapeutic potential.

关键词： Bortezomib Cancer therapy Immunoproteasome Multiplemyeloma Proteasome 20S Proteasome inhibitor Thymoproteasom

Implantable Electrochemical Microsensors for In Vivo Monitoring of Animal Physiological Information

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第3期16卷 183-211页

作者： Jin zhou Shenghan zhou Peidi Fan Xunjia Li Yibin Ying Jianfeng Ping Yuxiang Pan Laboratory of Agricultural Information Intelligent Sensing College of Biosystems Engineering and Food ScienceZhejiang UniversityHangzhou 310058People’s Republic of China ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang UniversityHangzhou 311200People’s Republic of China

In vivo monitoring of animal physiological information plays a crucial role in promptly alerting humans to potential diseases in animals and aiding in the exploration of mechanisms underlying human ***,implantable electrochemical microsensors have emerged as a prominent area of *** microsensors not only fulfill the technical requirements for monitoring animal physiological information but also offer an ideal platform for *** have been extensively studied for their ability to monitor animal physiological information in a minimally invasive manner,characterized by their bloodless,painless features,and exceptional *** development of implantable electrochemical microsensors for in vivo monitoring of animal physiological information has witnessed significant scientific and technological advancements through dedicated *** review commenced with a comprehensive discussion of the construction of microsensors,including the materials utilized and the methods employed for *** this,we proceeded to explore the various implantation technologies employed for electrochemical *** addition,a comprehensive overview was provided of the various applications of implantable electrochemical microsensors,specifically in the monitoring of diseases and the investigation of disease ***,a concise conclusion was conducted on the recent advancements and significant obstacles pertaining to the practical implementation of implantable electrochemical microsensors.

关键词： Electrochemical microsensors Implantable sensors In vivo monitoring Animal physiological information

Construction Activity Analysis of Workers Based on Human Posture Estimation Information

在线全文

学校读者我要写书评

暂无评论

Engineering 2024年第2期33卷 225-236页

作者： Xuhong zhou Shuai Li Jiepeng Liu zhou Wu Yohchia Frank Chen School of Civil Engineering Chongqing UniversityChongqing 400044China School of Automation Chongqing UniversityChongqing 400044China Department of Civil Engineering The Pennsylvania State UniversityMiddletownPA 17057USA

Identifying workers’construction activities or behaviors can enable managers to better monitor labor efficiency and construction ***,current activity analysis methods for construction workers rely solely on manual observations and recordings,which consumes considerable time and has high labor *** have focused on monitoring on-site construction activities of ***,when multiple workers are working together,current research cannot accu rately and automatically identify the construction *** research proposes a deep learning framework for the automated analysis of the construction activities of multiple *** this framework,multiple deep neural network models are designed and used to complete worker key point extraction,worker tracking,and worker construction activity *** designed framework was tested at an actual construction site,and activity recognition for multiple workers was performed,indicating the feasibility of the framework for the automated monitoring of work efficiency.

关键词： Pose estimation Activity analysis Object tracking Construction workers Automatic systems

Properties and Characteristics of Regolith-Based Materials for Extraterrestrial Construction

在线全文

学校读者我要写书评

暂无评论

Engineering 2024年第6期37卷 159-181页

作者： Cheng zhou Yuyue Gao Yan zhou Wei She Yusheng Shi Lieyun Ding Changwen Miao National Center of Technology Innovation for Digital Construction Huazhong University of Science and TechnologyWuhan 430074China School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan 430074China School of Materials Science and Engineering Southeast UniversityNanjing 214135China State Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The construction of extraterrestrial bases has become a new goal in the active exploration of deep *** the construction techniques,in situ resource-based construction is one of the most promising because of its good sustainability and acceptable economic cost,triggering the development of various types of extraterrestrial construction materials.A comprehensive survey and comparison of materials from the perspective of performance was conducted to provide suggestions for material selection and *** types of typical construction materials are discussed in terms of their reliability and applicability in extreme extraterrestrial ***,thermal and optical,and radiation-shielding properties are *** influencing factors and optimization methods for these properties are *** the perspective of material properties,the existing challenges lie in the comprehensive,long-term,and real characterization of regolith-based construction ***,the suggested future directions include the application of high-throughput characterization methods,accelerated durability tests,and conducting extraterrestrial experiments.

关键词： Extraterrestrial construction Characterization Mechanical property Thermal property Optical property Radiation-shielding

Source apportionment of PM_(2.5)using PMF combined online bulk and single-particle measurements:Contribution of fireworks and biomass burning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第2期136卷 325-336页

作者： Yanjing Zhang Wenshuai Li Lei Li Mei Li Zhen zhou Jianzhen Yu Yang zhou Frontier Science Center for Deep Ocean Multispheres and Earth System(FDOMES)and Physical Oceanography Laboratory Ocean University of ChinaQingdaoShandong 266100China College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdaoShandong 266100China Institute of Atmospheric Environment Safety and Pollution Control Jinan UniversityGuangdong 510632China Institute of Environment Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Department of Chemistry Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Division of Environment The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

Fireworks(FW)could significantly worsen air quality in short term during *** to similar tracers with biomass burning(BB),the fast and precise qualification of FW and BB is still *** this study,online bulk and single-particle measurements were combined to investigate the contributions of FW and BB to the overall mass concentrations of PM_(2.5)and specific chemical species by positive matrix factorization(PMF)during the Chinese New Year in Hong Kong in February *** combined information,fresh/aged FW(abundant ^(140)K_(2)NO_(3)^(+)and ^(213)K_(3)SO_(4)^(+)formed from ^(113)K_(2)Cl^(+)discharged by fresh FW)can be extracted from the fresh/aged BB sources,in addition to the Second Aerosol,Vehicles+Road Dust,and Sea Salt *** contributions of FW and BB were investigated during three high particle matter episodes influenced by the pollution transported from the Pearl River Delta *** fresh BB/FW contributed 39.2%and 19.6%to PM_(2.5)during the Lunar Chinese New Year ***,the contributions of aged FW/BB enhanced in the last two episodes due to the aging process,evidenced by high contributions from secondary ***,the fresh BB/FW showed more significant contributions to nitrate(35.1%and15.0%,respectively)compared with sulfate(25.1%and 5.9%,respectively)and OC(14.8%and11.1%,respectively)on *** comparison,the aged FW contributed more to sulfate(13.4%).Overall,combining online bulk and single-particle measurement data can combine both instruments’advantages and provide a new perspective for applying source apportionment of aerosols using PMF.

关键词： Source apportionment PMF Online bulk measurements Single particle analysis Fireworks Biomass burning

Seasonal increase in nest defense,but not egg rejection,in a cuckoo host

在线全文

学校读者我要写书评

暂无评论

Avian Research 2024年第1期15卷 50-54页

作者： Bo zhou Wei Liang Ministry of Education Key Laboratory for Ecology of Tropical Islands Key Laboratory of Tropical Animal and Plant Ecology of Hainan ProvinceCollege of Life SciencesHainan Normal UniversityHaikou 571158China Institute of Biological Resources Jiangxi Academy of ScienceNanchang 330096China

The interactions between avian brood parasites and their hosts provide an informative and easy-to-handle system for studying *** brood parasitism reduces the reproductive success of hosts,and thus,hosts have evolved anti-parasitic strategies,such as rejecting parasitic eggs and adopting aggressive nest defense strategies,to avoid the cost brought on by brood *** test whether host anti-parasitic strategies are adjusted with the risk of being parasitized when the breeding seasons of brood parasites and hosts are not synchronous,we conducted a field experiment assessing nest defense and egg recognition behaviors of the Isabelline Shrike(Lanius isabellinus),a host of the Common Cuckoo(Cuculus canorus).In the local area,the host Isabelline Shrike begins to breed in April,whereas the summer migratory Common Cuckoo migrates to the local area in May and begins to lay parasitic *** showed that nest defense behaviors of the Isabelline Shrike increases significantly after cuckoo arrival,showing higher aggressiveness to cuckoo dummies,with no significant difference in attack rates among cuckoo,sparrowhawk and dove dummies,but their egg rejection did not change *** results imply that Isabelline Shrikes may adjust their nest defense behavior,but not egg rejection behavior,with seasonality.

关键词： Aggression Anti-parasite strategy Egg rejection Mismatch cuckoo parasitism Nest defense

Fluidization stability and periodic fluctuations in gas–solid separation fluidized bed using Geldart A dense medium

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第7期90卷 522-534页

作者： Weijin Liu Dan Wang Liang Dong Enhui zhou Tatiana Aleksandrova Chenyang zhou Chenlong Duan Key Laboratory of Coal Processing and Efficient Utilization(China University of Mining&Technology) Ministry of EducationXuzhou 221116China School of Chemical Engineering&Technology China University of Mining&TechnologyXuzhou 221116China Department of Chemical and Biochemical Engineering The University of Western OntarioLondonOntario N6A 5B9Canada Mineral Processing Department Saint Petersburg Mining UniversitySt.Petersburg 199106Russia

Gas–solid separation fluidized bed is a typical method for coal separation without water *** A particles is also considered as the ideal dense medium to strengthen separation *** stability reflects the bed pressure fluctuations and the distribution of bubble and emulsion phases,affecting the separation *** the main frequency of pressure fluctuations can directly reflect the degree of pressure ***,the detailed fluidization stability is analyzed combined the method of standard deviation of pressure fluctuations,power spectral density,etc.,for Geldart A *** results showed that maintaining an appropriate gas velocity resulted in an average bed pressure of around 2000 *** main frequency is mainly concentrated around 1–1.5 ***,a prediction model of the main frequency of pressure fluctuations is established,and the error can be controlled within±*** investigation further proved the stable fluidization of Geldart A particles and provides a method for predicting the main frequency of pressure fluctuations in the gas–solid separation fluidized bed.

关键词： Geldart A dense medium Fluidization stability Periodic fluctuations Pressure fluctuations frequency Gas–solid separation fluidized bed

Cumulative Exposure to Natural Hazards and Mental Health in China: Are Older People More Vulnerable or More Resilient Than Younger and Middle-Aged Adults?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Disaster Risk Science 2024年第2期15卷 277-289页

作者： Shuai zhou Crystal Kwan Department of Applied Social Sciences The Hong Kong Polytechnic UniversityHong Kong 999077China

Despite the well-documented impacts of single natural hazards like earthquakes, less is known about the psychological adaptation to multiple natural hazards, particularly in rural areas. This study investigated the associations of multiple natural hazards with depression among Chinese adults. Data were retrieved from the China Family Panel Studies conducted during 2010–2018. With a sample of 11,633 Chinese adults, multilevel logistic regression was employed to examine the relationships between natural hazard exposure and depression in the total sample and different age groups. Overall, experiencing four or more natural hazards was associated with a higher risk of being depressed. Regarding hazard type, the number of hydrometeorological and biological hazards was associated with a higher likelihood of depression, whereas the number of geologic and other hazards was related to a lower risk of depression. Middle-aged adults from villages were more likely to be affected by natural hazard exposure than older and younger adults. The findings of this study show that cumulative exposure to natural hazards can generate lasting effects on depressive symptoms, particularly in middle adulthood. The findings also suggest that older adults from rural areas may have accumulated more resilience to mitigate the adverse well-being effects of hazard events. Policies and interventions should enhance disaster awareness and preparation for aging residents from multi-hazard communities.

关键词： Age differences China Depressive symptoms Multi-hazard communities Natural hazard exposure