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基于数据挖掘分析阳陵泉主治优势病症及配伍规律

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中国中医药图书情报杂志 2024年第2期48卷 85-92页

作者：李思慧刘书庆王玥梅余曙光吴巧凤成都中医药大学针灸推拿学院四川成都610075 成都中医药大学针灸与内稳态研究所四川成都610075

目的运用数据挖掘技术分析阳陵泉现代主治优势病症及腧穴配伍规律。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、PubMed、Web of Science及Embase建库至202... 详细信息

目的运用数据挖掘技术分析阳陵泉现代主治优势病症及腧穴配伍规律。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、PubMed、Web of Science及Embase建库至2022年12月31日收录的阳陵泉相关研究文献。建立阳陵泉单穴、配伍主治病症和配伍腧穴等数据库,利用Gephi0.10.1、SPSS Modeler 18.0、Cytoscape3.9.1、SPSS27.0软件对纳入文献进行复杂网络分析、关联分析和聚类分析。结果纳入文献530篇,阳陵泉单穴主治病症37种,优势病症为肩关节周围炎、落枕、急性胆囊炎及踝关节扭伤等,治疗方式以运动针法为主;配伍主治病症105种,优势病症为膝骨关节炎、腰椎间盘突出症及偏头痛等24种,治疗方式以电针为主。阳陵泉高频配伍特定穴为五输穴、交会穴、下合穴,高频配穴为足三里、血海、三阴交、阴陵泉、犊鼻、内膝眼等17个腧穴,配伍经脉主要为足阳明胃经,聚类分析共得3系4类配伍处方组合。结论阳陵泉主治范围广泛,以运动系统病症为主,单穴、配伍应用各有优势病症。特定穴多重配伍与聚类处方灵活组合,有助于临床精准选穴、科学用穴。

关键词：阳陵泉优势病症腧穴配伍规律数据挖掘

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针刺治疗慢性阻塞性肺疾病的机制研究进展

上海中医药杂志 2024年第6期58卷 12-16页

作者：杨佐琴徐桂兴付雪何斌秦尔奇余曙光梁繁荣成都中医药大学附属第三医院/成都中医药大学第三临床医学院/成都市郫都区中医医院针灸科四川成都611730 成都中医药大学针灸推拿学院四川成都610075 四川省针灸临床医学研究中心四川成都610075

慢性阻塞性肺疾病(COPD)是一种以持续性呼吸困难伴咳嗽及痰液生成为主要症状的进展性的气道反应疾病。针刺作为一种非药物疗法在COPD治疗中扮演越来越重要的角色。目前针刺治疗COPD的机制研究主要集中在炎症、免疫调节、氧化应激等方面... 详细信息

慢性阻塞性肺疾病(COPD)是一种以持续性呼吸困难伴咳嗽及痰液生成为主要症状的进展性的气道反应疾病。针刺作为一种非药物疗法在COPD治疗中扮演越来越重要的角色。目前针刺治疗COPD的机制研究主要集中在炎症、免疫调节、氧化应激等方面,针刺通过以上调节机制作用于气道平滑肌,减轻其痉挛从而改善气流限制,改善肺部及全身炎症性反应而发挥治疗作用,但针刺的作用机制仍有待进一步深入研究。对针刺治疗COPD的相关机制研究进行梳理归纳,以期为揭示针刺治疗COPD的相关机制提供一定依据。

关键词：慢性阻塞性肺疾病针刺非药物疗法炎症反应免疫调节作用机制

Symptoms of long-term exposure to moxa smoke in acupuncturists： a correlation analysis

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Journal of Traditional Chinese Medicine 2018年第1期38卷 132-138页

作者： Wang Xiang yu Chang Tang Yong Chang Shyang Yang Hui Zhang He Jiaozi Zhang yueyue Jiao Yang Zhuang Zhiqi Yin Haiyan Zhang Chengshun Lu Peng Wu Qiaofeng yu shuguang Acupuncture and Tuina College Chengdu University of Traditional Chinese Medicine Chengdu 610075 China Departmnet of rehabilitation The First Affiliated Hospital of Xi'an Medical University Xi'an 710077 China Department of Electrical Engineering National Tsing Hua University Hsinchu 300 China Taiwan Institute of Acupuncture and Homeostasis Regulation Chengdu 610075 China

OBJECTIVE: To investigate the effects of long-term exposure to moxa smoke on acupuncturists and to consider the association between physical symptoms and gender, age, secondhand smoke(SHS) exposure, and the duration of ***: A self-report, web-based questionnaire was used to evaluate the effects of moxa smoke onacupuncturists. Logistic regression was used to analyze the relationship between physical symptoms and possible correlative ***: A total of 858 questionnaires were analyzed. The data showed that 42.42% of acupuncturists had been exposed to moxa smoke for 5-10 years. The most frequent symptom was tearing(32.98%) and the least frequent symptom was asthma(5.24%). Logistic regression analysis showed that female acupuncturists were slightly more susceptible to cough and tearing than males(cough:OR: 1.583, 95% CI: 1.079, 2.321, P = 0.019; tearing:OR: 1.519, 95% CI: 1.094, 2.108, P = 0.013). Acupuncturists aged over 25 years reported a slightly lower incidence of eye itchiness than those aged under25 years(26-40 years: OR: 0.604, 95% CI: 0.379,0.965, P = 0.035; over 40 years: OR: 0.330, 95% CI:0.114, 0.958, P = 0.042). Ophthalmodynia occurred less in acupuncturists aged 26-40 years(OR: 0.591,95% CI: 0.359, 0.970, P = 0.038) than in those younger than 25 years. The only association between prevalence of symptoms and tobacco use and SHS exposure was that smokers had a lower occurrence of phlegm in the throat(OR: 0.579, 95% CI: 0.392,0.856, P = 0.006). Shortness of breath was less frequent in participants exposed to moxa smoke for more than 5 years(5-10 years: OR: 0.400, 95% CI:0.204, 0.785, P = 0.008; 11-20 years: OR: 0.392, 95%CI: 0.178, 0.864, P = 0.02), but a slightly higher incidence of eye itchiness was found in those with over20 years of moxa exposure(OR: 4.200, 95% CI:1.344, 3.128, P = 0.014).CONCLUSION: The most frequent symptom of moxa smoke exposure in acupuncturists was tear-ing. The association of symptoms with age and duration of e

关键词： Moxibustion Smoking, non-tobacco product Acupuncturists Signs and symptoms Lo- gistic model

Aboveground carbon sequestration of Cunninghamia lanceolata forests:Magnitude and drivers

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Forest Ecosystems 2024年第1期11卷 32-41页

作者： Chen Wang shuguang Liu yu Zhu Andrew R.Smith Ying Ning Deming Deng National Engineering Laboratory for Applied Technology of Forestry&Ecology in South China Central South University of Forestry and TechnologyChangsha 410004China Technology Innovation Center for Ecological Conservation and Restoration in Dongting Lake Basin Ministry of Natural ResourcesChangsha 410007China College of Life Science and Technology Central South University of Forestry and TechnologyChangsha 410004China School of Ecology and Environment Hainan UniversityHaikou 570228China School of Natural Sciences Bangor UniversityGwyneddLL572UWUK College of Forestry Central South University of Forestry and TechnologyChangsha 410004China Hunan Prospecting Designing&Research General Institute for Agriculture Forestry&IndustryChangsha 410007China

Understanding the spatial variation,temporal changes,and their underlying driving forces of carbon sequestration in various forests is of great importance for understanding the carbon cycle and carbon management *** carbon density and sequestration in various Cunninghamia lanceolata forests,extensively cultivated for timber production in subtropical China,vary with biodiversity,forest structure,environment,and cultural factors remain poorly explored,presenting a critical knowledge gap for realizing carbon sequestration supply potential through *** on a large-scale database of 449 permanent forest inventory plots,we quantified the spatial-temporal heterogeneity of aboveground carbon densities and carbon accumulation rates in Cunninghamia lanceolate forests in Hunan Province,China,and attributed the contributions of stand structure,environmental,and management factors to the heterogeneity using quantile age-sequence analysis,partial least squares path modeling(PLS-PM),and hot-spot *** results showed lower values of carbon density and sequestration on average,in comparison with other forests in the same climate zone(i.e.,subtropics),with pronounced spatial and temporal ***,quantile regression analysis using carbon accumulation rates along an age sequence showed large differences in carbon sequestration rates among underperformed and outperformed forests(0.50 and 1.80 Mg·ha^(-1)·yr^(-1)).PLS-PM demonstrated that maximum DBH and stand density were the main crucial drivers of aboveground carbon density from young to mature ***,species diversity and geotopographic factors were the significant factors causing the large discrepancy in aboveground carbon density change between low-and high-carbon-bearing *** analysis revealed the importance of culture attributes in shaping the geospatial patterns of carbon *** work highlighted that retaining largesized DBH trees and increasing shade-t

关键词： Carbon density Carbon accumulation rate Forest age Spatial variation Cultural influence

Simultaneous Degradation, Dehalogenation, and Detoxification of Halogenated Antibiotics by Carbon Dioxide Radical Anions

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Engineering 2024年第6期37卷 78-86页

作者： Yanzhou Ding Xia yu shuguang Lyu Huajun Zhen Wentao Zhao Cheng Peng Jiaxi Wang Yiwen Zhu Chengfei Zhu Lei Zhou Qian Sui State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process School of Resources and Environmental EngineeringEast China University of Science and TechnologyShanghai 200237China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Academy of Environmental Sciences Shanghai 200233China

Despite the extensive application of advanced oxidation processes(AOPs)in water treatment,the efficiency of AOPs in eliminating various emerging contaminants such as halogenated antibiotics is constrained by a number of *** moieties exhibit strong resistance to oxidative radicals,affecting the dehalogenation and detoxification *** address these limitations of AOPs,advanced reduction processes(ARPs)have been ***,a novel nucleophilic reductant—namely,the carbon dioxide radical anion(CO_(2)^(·-))—is introduced for the simultaneous degradation,dehalogenation,and detoxification of florfenicol(FF),a typical halogenated *** results demonstrate that FF is completely eliminated by CO_(2)^(·-),with approximately 100%of Cland 46%of Freleased after 120 min of *** detoxification is observed,which exhibits a linear response to the release of free inorganic halogen ions(R^(2)=0.97,p75%)in degrading a series of halogenated antibiotics,including chloramphenicol(CAP),thiamphenicol(THA),diclofenac(DLF),triclosan(TCS),and ciprofloxacin(CIP).The system shows high tolerance to the pH of the solution and the presence of natural water constituents,and demonstrates an excellent degradation performance in actual groundwater,indicating the strong application potential of CO_(2)^(·-)-based ARPs in real ***,this study elucidates the feasibility of CO_(2)^(·-)for the simultaneous degradation,dehalogenation,and detoxification of halog

关键词： Carbon dioxide radical anions Advanced reduction processes Halogenated antibiotics Dehalogenation Detoxification

针灸推拿行业人才队伍建设的现状和发展趋势探讨

维普期刊数据库评论

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中国针灸 2018年第8期38卷 901-906页

作者：余常余曙光成都中医药大学针灸推拿学院四川成都610075

笔者就针灸推拿行业人才队伍发展现状进行综述,并探讨行业人才发展趋势,分析存在问题,提出相关建议。认为针灸推拿行业人才队伍总体规模、临床和科研人才队伍规模均明显增长,特别是高端人才发展在中医类人才中较为突出。中医药院校教育... 详细信息

笔者就针灸推拿行业人才队伍发展现状进行综述,并探讨行业人才发展趋势,分析存在问题,提出相关建议。认为针灸推拿行业人才队伍总体规模、临床和科研人才队伍规模均明显增长,特别是高端人才发展在中医类人才中较为突出。中医药院校教育针灸推拿人才培养规模的特点为:专科层次增长速度高于本科,专业硕士规模下降,博士层次规模保持平稳。为满足社会对行业人才需求不断增长的要求,以及行业本身迅速发展的要求,应进一步加大针灸人才队伍建设力度,着力加强基层临床人才的培养和高端科研人才队伍的建设。

关键词：针灸推拿人才队伍建设现状发展趋势

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中国政府信任类型的历史嬗变与现实思考

重庆大学学报（社会科学版） 2016年第1期22卷 217-222页

作者：余曙光全薇重庆大学公共管理学院重庆400044

政府信任类型是一定时代社会、经济的产物。基于信任关系的表现形态,建国以来已经经历了政府信任的依赖型、松散型和互动型三种类型的嬗变。三种类型在表现形态、结构功能和实际效应上都有明显的差异。笔者通过分析比较,重点探讨了互动... 详细信息

政府信任类型是一定时代社会、经济的产物。基于信任关系的表现形态,建国以来已经经历了政府信任的依赖型、松散型和互动型三种类型的嬗变。三种类型在表现形态、结构功能和实际效应上都有明显的差异。笔者通过分析比较,重点探讨了互动型政府信任的时代合理性及其发展趋势,并有针对性地从观念、机制、主体、关系、危机应对等五个方面提出了进一步完善政府信任的对策。

关键词：政府信任信任类型历史嬗变

Treatment Effects of Acupuncture and Calligraphy Training on Cognitive Abilities in Senile Demented Patients

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Chinese Medicine and Culture 2019年第2期2卷 95-98页

作者： Henry S.R.Kao Miqu Wang shuguang yu Shihong yuan Miranda MY Fung Lin Zhu Stewart P.W.Lam Tin Tin Kao Xiaoyang Kao Departments of Psychology 9Psychology and GeographyUniversity of Hong KongHKSAR Calligraphy Therapy Research Laboratory Shenzhen Institute of NeuroscienceShenzhen Institute of Psychology and Genetics of Chinese Medicine School of Acup uncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu Department of Medicine Shanxi Medical College for Continuing Education Beijing Tong Ren Tang Chinese Medicine Clinic Beijing Tong Ren Tang Taiyuan Chinese Medicine Hospital Department of Chinese Medicine China Academy of Chinese Medical Sciences Division of Research Advocacy 21^st Century Education Research InstituteBeijingChina 不详 Department of Electrical Engineering University of Illinois at Urbana-ChampaignChampaignIllinoisUSA

Purpose:This study compared the relative effectiveness of Chinese calligraphy handwriting(CCH)and acupuncture in the treatment of patients with senile *** and Methods:A randomized controlled trial(RCT)with 17 mild-to-moderate dementia patients with an average age of 77.29 years were randomly assigned with 9 to the calligraphy handwriting group and 8 to the acupuncture treatment group for a month of consecutive *** participants'cognitive abilities,as well as symptoms of senile dementia,were measured by the Chinese version of the Mini-mental State Examination(CMMSE)and the Chinese Medicine Quantitative Diagnostic Survey for Senile Dementia Symptoms,respectively,before and after the ***:The calligraphy group showed a significant increase in calculation and memory as well as a decline in the symptoms of senile *** in the acupuncture group experienced a significant growth in total CMMSE scores and the subscales in orientation to time and place,behavioral operations,as well as reduced clinical ***,no significant changes were found in their memory and calculation ***:Both CCH and acupuncture treatments were found significantly effective for,respectively,enhancing the patients'cognitive abilities and reducing their clinical ***,calligraphy handwriting also improved the level of their attention and concentration,physical relaxation,and emotional stability.

关键词： Acupuncture calligraphy handwriting cognitive abilities senile dementia

基于自主研发ACU&MOX-DATA平台探索腧穴功效特点研究

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中国中医药信息杂志 2024年第2期31卷 64-69页

作者：李思慧刘书庆唐强张瑞斌陈伟洪浩朱冰梅蓝勋王勇余曙光吴巧凤成都中医药大学针灸推拿学院四川成都610075 成都中医药大学针灸与内稳态研究所四川成都610075 成都中医药大学创新研究院四川成都610075 四川大学华西医院四川成都610044 清华大学医学院北京100084 中国科学院数学与系统科学研究院北京100190

目的基于ACU&MOX-DATA平台,初步明确不同腧穴、不同靶器官及不同刺灸法对腧穴功效的影响,并可视化展示相关结果是否存在腧穴功效“特性”“共性”的特点。方法以原创组学数据和公共组学数据整合后获得的多源异构数据作为数据源,经标准... 详细信息

目的基于ACU&MOX-DATA平台,初步明确不同腧穴、不同靶器官及不同刺灸法对腧穴功效的影响,并可视化展示相关结果是否存在腧穴功效“特性”“共性”的特点。方法以原创组学数据和公共组学数据整合后获得的多源异构数据作为数据源,经标准化处理后,利用ACU&MOX-DATA平台中Batch Search、Stimulation Mode等模块对不同腧穴、不同靶器官、不同刺灸法的数据进行差异基因分析、疾病病理网络分析和富集分析。结果在同一疾病状态、同一干预措施下,不同腧穴间存在效应差异;在同一疾病状态、同一腧穴及干预措施下,不同靶器官产生的应答不完全一致;在同一疾病状态、同一腧穴下,不同干预措施间存在效应差异。结论基于ACU&MOX-DATA平台,初步明确腧穴、靶器官、刺灸法是影响腧穴功效的关键因素,上述结果间存在腧穴功效的特异性或共性调节特点。将ACU&MOX-DATA平台应用于针灸学领域关键科学问题的分析和可视化解读,可为深化腧穴认知、指导临床选穴、提高针灸临床疗效等提供参考。

关键词：腧穴功效针灸干预方式靶器官响应多组学数据异源数据分析