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Chinese Journal of Polymer Science 2019年第1期37卷 1-10页

作者： shu-yan jiang Xin Zhao CAS Key Laboratory of Synthetic and Self-assembly Chemistry for Organic Functional Molecules Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry Chinese Academy of Sciences

Two-dimensional(2D) materials have been demonstrated to exhibit unique properties originating from its 2D nature. In recent years, the construction of 2D materials has become a topic of great interest. This article summarizes the recent advance of 2D supramolecular organic frameworks(SOFs) which are homogeneously constructed in solution phase through self-assembly of rationally designed building blocks. These 2D SOFs are soluble and still maintain stable network structures in solutions, which exhibit uniqueness not only in structures but also in properties. In this concise review, the SOFs-related background is briefly introduced firstly, followed by outlining the research progress of soluble 2D SOFs from the perspective of monomer design, assembly, and structural *** article ends with a personal outlook on the future development of this new class of supramolecular polymers.

关键词： Supramolecular organic frameworks(SOFs) Self-assembly Two-dimensional Supramolecular polymers

Toward a Two-Dimensional Supramolecular Organic Framework with High Degree of Internal Order via Amphiphilic Modification

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CCS Chemistry 2022年第1期4卷 141-150页

作者： Zhi-Jian Yin shu-yan jiang Na Liu Qiao-yan Qi Zong-Quan Wu Tian-Guang Zhan Xin Zhao Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules Center for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032 Department of Polymer Science and Engineering School of Chemistry and Chemical EngineeringHefei University of TechnologyAnhui ProvinceHefei 230009 Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Life SciencesZhejiang Normal UniversityJinhua 321004

Solution-phase self-assembly of two-dimensional(2D)networks with a high degree of internal order and long-range periodicity is a great ***,we report a rational design to improve 2D self-assembly in water through amphiphilic modification of the building *** amphiphilic tritopic molecule(1)is designed and synthesized by introducing three hydrophilic oligo(ethylene glycol)moieties and three hydrophobic hexyl *** assembly of 1 and cucurbit[8]uril(CB[8])leads to the formation of a Janus 2D supramolecular organic framework(SOF),which further creates unique bilayer supramolecular networks and exhibits an unprecedentedly high degree of internal order and long-range *** contrast,the assembly of a nonamphiphilic analog(2)with CB[8]only generates a 2D SOF with a lower degree of internal order,suggesting that the inherent amphiphilicity of 1 plays a crucial role in improving its 2D self-assembly in aqueous phase.

关键词： self-assembly supramolecular organic frameworks two-dimensional amphiphilicity internal order

Fault Tolerant Reconfigurable System with Dual-Module Redundancy and Dynamic Reconfiguration

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Journal of Electronic Science and Technology 2011年第2期9卷 167-173页

作者： Qi-Zhong Zhou Xuan Xie Jing-Chen Nan Yong-Le Xie shu-yan jiang School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Intel Corporation Chengdu 611731China School of Physics and Electronic Engineering Yibin UniversityYibin 644000China

To handle the effects of single event upsets（SEU）,which are common to computers in space radiation environment,a new fault-tolerant system with dual-module redundancy is proposed using dynamic reconfigurable technique of field programmable gate array（FPGA）. This system contains detection and backup alternative functions,that is,the self-detection and self-healing functions can be completed,and consequently a system design with low hardware redundancy and high resource utilization can be achieved successfully. So it can not only detect fault but also repair the fault effectively after failure. Hence,this method is especially practical to the dynamically reconfigurable computers based on FPGAs. Design methodology has been verified by Virtex-4 FPGA on Xilinx Ml403 development platform.

关键词： Dependable computers fault-tolerant field programmable gate array self-detection single event upsets

Field Application of the 3rd-Generation FJC Series Jet Type Coal Flotation Machine in China

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煤炭加工与综合利用 2006年第5期 76-78页

作者： ZHAO shu-yan,jiang Ming-dong,XU Hong-na,Gu Shao-xiong,WU Da-wei (Tangshan Guohua Technology Co.,Ltd.,Tangshan 063020,Hebei,China)

Since the successful introduction of the jet flotation cell in the 80s of the last century,extensive theoretical and experimental work has been continuously conducted for the optimization and renovation of the structural parameters of the trough,aerator-agitator mechanism,the pattern of pulp flow in cell and the pulp feeding mode of this kind of cell. Based on the result of the study and through optimum selection of a pulp circulating pump capable of working with a higher efficiency and longer service life in collaboration with the specialized pump producer,the 3rd-generation FJC series jet flotation cell (FJC cell for short) was successfully developed. Now,7 sizes of the FJC cells are available,with a unit volume per cell ranging from 4m3 to 20m3 (See Table 1). These cells are now in operation at 130-odd coal preparation plants.

关键词： Field Application of the 3rd-Generation FJC Series Jet Type Coal Flotation Machine in China BWD

Possible involvement of amino acids in the central regulation of cardiovascular responses in conscious rats

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Possible involvement of amino acids in the central regulatio...

Non-coding RNAs in acute ischemic stroke:from brain to periphery

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Qing-Hua JIN,Gui-Yu CUI,Xian-shu SHEN,yan jiang,yan-Hua BING,Xiao-Lei GAO,Gui-Dong YIN Department of Physiology,yanbian University College of Medicine,yanji 133000,China

＜正＞The paraventricular nuclues of the hypothalamus（PVN） is a central site for the integration of the neuroendocrine system and the autonomic nervous *** PVN appears to be an important regulatory region of the hypothalamus that plays a critical role in the regulation of cardiovascular ***,the neurochemical mechanisms in the PVN that are responsible for the regulation of cardiaovascular responses have not been fully ***,in the present study,we use microdialysis,microinjection and high-performance liquid chromatography technique to investigate the possible involvement of several amino acids of the PVN on cardiovascular responses in freely moving conscious rats. The results will contribute to clarify the central mechanism of the cardiaovascular regulation.

关键词： PVN amino acids cardiovascular responses microdialysis conscious rats

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Neural Regeneration Research 2025年第1期20卷 116-129页

作者： shuo Li Zhaohan Xu Shiyao Zhang Huiling Sun Xiaodan Qin Lin Zhu Teng jiang Junshan Zhou Fuling yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress

Lipid levels and insulin resistance markers in patients with colorectal cancer:Propensity score matching analysis

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 130-142页

作者： Ren-Hao Hu Dong-Yi yan Ke-Hui Zhang Di Zhang Xi-Mao Cui Xiao-Hua jiang shun Zhang Department of Gastrointestinal Surgery Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China School of Medicine Tongji UniversityShanghai 200092China Department of Emergency Medicine Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

BACKGROUND Colorectal cancer(CRC)is a prevalent malignant neoplasm characterized by subtle early *** To investigate the correlation among serum lipid profiles,the triglyceride-glucose(TyG)index,and the atherosclerotic index(AI)in patients with ***,it explored the clinical diagnostic utility of combining serum lipids with cancer antigens in the context of *** A retrospective analysis encompassed 277 patients with CRC and 1034 healthy *** Following propensity score matching,patients with CRC exhibited significantly reduced levels of serum triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol,and low-density lipoprotein cholesterol(LDL-C),as well as a diminished TyG ***,they displayed elevated AI levels compared to their healthy *** in advanced stages exhibited lower serum levels of TG,TC,and LDL-C compared to those in early *** with positive lymph node metastasis demonstrated reduced levels of TG,LDL-C,and the TyG *** operating characteristic analysis revealed that the combination of the TyG index,carcinoembryonic antigen,and carbohydrate antigen 19-9 yielded the highest positive prediction rate for CRC at 75.3%.CONCLUSION Preoperative serum lipid profiles exhibit a robust association with patients with *** concurrent assessment of multiple serum lipids and cancer antigens effectively enhances the diagnostic accuracy for CRC.

关键词： Colorectal cancer Serum lipids Triglyceride-glucose index Atherosclerotic index Diagnostic marker

Maternal and fetal death associated with acute pancreatitis during pregnancy:A case report

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World Journal of Clinical Cases 2025年第10期13卷 53-58页

作者： Jin Li Qing-yan Zhang Mei-Hong Zhang Shan-Yun jiang Department of Anesthesiology Kaihua County People’s HospitalQuzhou 324300Zhejiang ProvinceChina Center for Clinical Inspection and Quarantine Kaihua County Center for Clinical Inspection and QuarantineQuzhou 324300Zhejiang ProvinceChina

BACKGROUND Acute pancreatitis in pregnancy is a rare but serious condition that can lead to high maternal mortality and fetal *** of pregnancy complicated by severe acute pancreatitis,particularly with subsequent respiratory and cardiac arrest,are rarely *** SUMMARY We present the case of a 35-year-old woman,at 36+5 weeks of gestation,who presented with paroxysmal epigastric pain accompanied by low back pain,nausea,and *** to the clinical symptoms,B-ultrasound imaging and biochemical indicators,the patient was diagnosed with acute pancreatitis and initially managed ***,3 hours after admission,the patient experienced respiratory and cardiac arrest,and the fetus *** this case,the adverse outcomes occurred due to the lack of aggressive fluid resuscitation and an active surgical *** Implementing aggressive fluid resuscitation to sustain tissue perfusion,alongside the proactive evaluation of pharmacological agents that suppress gastric acid secretion and inhibit pancreatic enzyme activity,may be beneficial in mitigating the risk of a severely adverse *** management of acute pancreatitis during pregnancy requires careful timing of surgical intervention,a thorough evaluation of the risks and benefits regarding the continuation or termination of pregnancy,and a focus on safeguarding both maternal and fetal health.

关键词： Severe acute pancreatitis Pregnancy Cardiac arrest Fetal death Case report

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

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Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao yan Song Yahong Cheng Tong Li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

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中国的女孩生存:历史、现状和展望

市场与人口分析 2006年第1期12卷 2-16页

作者：李树茁韦艳姜全保西安交通大学公共政策与管理学院人口与发展研究所西安710049

基于已有的数据、研究成果及中国政府和社会的干预实践,对有关改善中国女孩生存的研究和实践进行回顾式的评述和展望。中国一直存在对女性的歧视,近年来中国持续升高的出生性别比和偏高的女孩死亡水平,反映出女性社会地位低下和女孩生... 详细信息

基于已有的数据、研究成果及中国政府和社会的干预实践,对有关改善中国女孩生存的研究和实践进行回顾式的评述和展望。中国一直存在对女性的歧视,近年来中国持续升高的出生性别比和偏高的女孩死亡水平,反映出女性社会地位低下和女孩生存风险恶化。对女孩的歧视包括出生前和出生后的歧视。描述了中国高出生性别比和偏高女孩死亡水平的水平、趋势和区域差异,分析了女孩生存环境恶化的直接和间接原因及其引发的人口和社会后果。通过比较国际社会的经验和中国政府及社会的认识与行动,讨论了改善中国女孩生存的前景及相应的措施。

关键词：女孩生存出生性别比女孩死亡水平中国