检索结果-南通市图书馆

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

不同保水剂对土壤物理性质影响的探究

节水灌溉 2016年第10期 10-14页

作者：许紫峻韩舒师庆东新疆大学资源与环境科学学院乌鲁木齐830046 新疆绿洲生态重点实验室乌鲁木齐830046

保水剂的研究多集中于保水性和持水性,关于保水剂对土壤物理性质影响的研究还不多见,因此,选取市场上的MP3005KCE、沃特和HG-60等3种保水剂,对沙土、壤土和黏土作用能力进行分析。结果表明:1增加3种土壤的水稳性团聚体的比例,增加幅度为... 详细信息

保水剂的研究多集中于保水性和持水性,关于保水剂对土壤物理性质影响的研究还不多见,因此,选取市场上的MP3005KCE、沃特和HG-60等3种保水剂,对沙土、壤土和黏土作用能力进行分析。结果表明:1增加3种土壤的水稳性团聚体的比例,增加幅度为HG-60>沃特>MP3005KCE,其中MP3005KCE对改善沙土和壤土的通气性能较其他两种保水剂明显;2膨胀率均明显增加(p沃特>MP3005KCE;从膨胀均匀程度来看沙土中MP3005KCE>沃特>HG-60,壤土中沃特>MP3005KCE>HG-60,而黏土中都不均匀;3土壤密度均显著降低(p沃特>MP3005KCE;随着保水剂施加的不断增加,土壤密度逐渐降低,土壤孔隙度逐渐增加;当保水剂的浓度超过0.5%后对土壤密度和孔隙度改善的效果并不明显增加(p>0.05)。为保水剂在干旱区的应用提供重要参考价值。

关键词：保水剂水稳性团聚体土壤密度膨胀率孔隙度

High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 187-203页

作者： Si Chen Fang Huang Lijie Mao Zhimin Zhang han Lin Qixin Yan Xiangyu Lu Jianlin shi Department of Cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science Center of Nanocatalytic Medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with *** constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

Effects of Shenqi Xiangyi granules in advanced gastric cancer chemotherapy

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 169-175页

作者： Xiao-Jing shi Yu Song Xue-Xue Liang Ting Chen Huang-Yu Hao Xue han Ya-Nan Chen Department of Oncology Zhangjiagang First People's HospitalSuzhou 215600Jiangsu ProvinceChina

BACKGROUND Owing to the absence of specific symptoms in early-stage gastric cancer,most patients are diagnosed at intermediate or advanced *** a result,treatment often shifts from surgery to other therapies,with chemotherapy and targeted therapies being the primary options for advanced gastric cancer treatment.A total of 116 patients with advanced gastric cancer,admitted from January 2021 to December 2023,were selected and divided into two groups of 58 each using the random number table *** control group received FOLFOX4 chemothe-rapy(oxaliplatin+calcium+folinate+5-fluorouracil)combined with intravenous *** observation group received the same treatment as the control group,supplemented by oral administration of Senqi shiyiwei *** groups underwent treatment cycles of 3 weeks,with a minimum of two *** therapeutic efficacy,immune mechanisms,and treatment-related toxicity and side effects were compared between the *** objective remission rate in the observation group(55.17%)was higher than that of the control group(36.21%)(P0.05).CONCLUSION Adjuvant therapy with Shenqixian granules may enhance the efficacy of simudizumab combined with FOLFOX4 chemotherapy in advanced gastric cancer and the immune function by increasing immune cell counts,making it a valuable option in clinical treatment.

关键词： Sindilizumab FOLFOX4 chemotherapy Advanced gastric cancer Ginseng Qi Xiangyi granule Clinic treatment

16S rRNA Gene Probe Quantitates Residual Host Cell DNA in Pharmaceutical-Grade Plasmid DNA

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

16S rRNA Gene Probe Quantitates Residual Host Cell DNA in Ph...

SO2与H2O对商用钒钨钛脱硝催化剂毒化作用综述

2005全国第二届核酸疫苗研讨会

作者： WANG Kai-Yu GUO Ying-Jun SUN shu-han shi Ke ZhanG shu WANG Kai-Hui ZhanG Yi CHEN Zu-Huan (Department of Medical Genetics, Second Military Medical University, 800 Xiang’Yin Road, Shanghai 200433, China)

The development and widespread use of DNA-based vaccination against infectious pathogens have been a great triumph of medical science. Quality control of DNA vaccines as biopharmaceutical productions is a problem to solve. Residual genomic DNA of engineering bacteria has been identified as a potential risk factor, so whose level must be controlled under the regulatory standards. We report a dot-blot hybridization method to detect residual host cell DNA in purified DNA vaccines. The assay utilizes PCR amplified and digoxigenin-labeled E. coli 16S rRNA gene as probe. The sensitivity of the dot-blot hybridization assay with E. coli 16S rRNA gene probe was evaluated in comparison with single copy uidR gene probe. The optimized dot-blot hybridization assay had both low background and a suitable sensitivity, detecting 10 pg of residual E. coli DNA. The method is suitable in the routine use of measuring the levels of residual E. coli DNA in the pharmaceutical-grade DNA vaccine.

关键词： DNA vaccine 16S

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国电力 2016年第12期49卷 168-173页

作者：余岳溪廖永进束航史雅娟张亚平杨林军广东电网有限责任公司电力科学研究院广东广州510080 东南大学能源与环境学院能源热转换及其过程测控教育部重点实验室江苏南京210096

选择性催化还原(SCR)脱硝技术在火电厂得到广泛应用,烟气组分对催化剂的性能影响及催化剂中毒、细颗粒物产生是当前研究热点。综述重点探讨了工业烟气中SO_2、水蒸气(H_2O)对商用钒钨钛脱硝催化剂的毒化机理、影响因素及控制措施。SO_2... 详细信息

选择性催化还原(SCR)脱硝技术在火电厂得到广泛应用,烟气组分对催化剂的性能影响及催化剂中毒、细颗粒物产生是当前研究热点。综述重点探讨了工业烟气中SO_2、水蒸气(H_2O)对商用钒钨钛脱硝催化剂的毒化机理、影响因素及控制措施。SO_2的毒化机理主要包括硫酸铵盐的覆盖堵塞,催化剂表面活性点位的硫酸盐金属化,以及SO_2与NH3、NO的竞争吸附等;H_2O的毒化机理主要是其与NH_3、NO竞争吸附降低了催化剂的脱硝效率,并促进产生大量的硫酸铵盐,以及阻碍硫酸铵盐与NO的降解反应等。

关键词：烟气脱硝选择性催化还原催化剂中毒 SO2 H2O 硫酸氢铵

Effect of Ti on Austenite Grain Growth Behavior in High Carbon Steels

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2014年第7期21卷 702-709页

作者： han MA shu-lun LIAO shi-fang WANG Institute of Research of Iron and Steel Shasteel

Austenite grain growth behavior of two high carbon steels was observed using Confocal *** Scanning Mi croscope （CLSM）. Apparent austenite grain sizes for different holding time under a series of temperatures were measured by employing linear intercept method. Experimental results showed that Ti bearing steel exhibited a much sluggish growth rate compared with Ti free counterpart, which was attributed to the pinning effect of Ti（C,N） nan oparticles with the size of 20 to 40 nm on austenite grain boundaries. Based on the research conducted by using Transmission Electron Microscope （TEM） observation and Thermo Calc calculation, Ti（C, N） was confirmed to be the dominant phase at elevated temperature. Some models were introduced to predict the grain sizes of both steels. By comparison, the results predicted by the modified Gladman equation are found to be closest to the experimental resuits, which could be employed to predict accurately the austenite grain growth of high carbon steels.

关键词： grain growth austenite high carbon steel titanium CLSM

在线全文

学校读者我要写书评

暂无评论

干细胞的趋电性迁移及机制

中国组织工程研究 2025年第23期29卷 4984-4992页

作者：韩芳舒晴贾绍辉田峻武汉体育学院运动医学院湖北省武汉市430079 武汉大学中南医院骨科康复科湖北省武汉市430071

背景:随着对干细胞技术研究的深入,如何使其准确归巢成为临床应用中的一大难题。除药物和趋化因子等信号的诱导外,电场也被广泛应用于指导干细胞的定向迁移,并可增强其迁移速度和定向性。目的:旨在分析总结电场对干细胞迁移特性的影响,... 详细信息

背景:随着对干细胞技术研究的深入,如何使其准确归巢成为临床应用中的一大难题。除药物和趋化因子等信号的诱导外,电场也被广泛应用于指导干细胞的定向迁移,并可增强其迁移速度和定向性。目的:旨在分析总结电场对干细胞迁移特性的影响,同时综述可能的作用机制。方法:通过检索Pub Med和中国知网数据库,收集截至2024年3月的相关文献,英文检索词:“stem cells,direct current electric field,pulsed electric field,migration,electric field device,mechanism”;中文检索词:“干细胞,直流电场,脉冲电场,迁移,电场装置,机制”。排除不能获取全文和与主题无关的文献。结果与结论:根据筛选要求共纳入58篇文献,包括中文文献15篇及英文文献43篇。文献以脂肪间充质干细胞、骨髓间充质干细胞、神经干细胞、表皮干细胞、人胚胎干细胞和人诱导性多功能干细胞为研究对象,在迁移装置中研究电场的不同参数对上述干细胞迁移的影响及其机制。(1)电场作为一种简单、无创且稳定的干预方式在指导干细胞定向迁移的过程中起着积极作用;(2)不同类型的干细胞发生趋电性迁移的方向不同,同时大部分干细胞的迁移速度和定向性是随着电场强度增加而增加的;(3)不同的电场装置在观测干细胞迁移时的侧重点不同,可根据实验目的而择优选择相关装置;(4)不同干细胞趋电性迁移的机制不完全相同,多数干细胞迁移过程中有MAPK通路、ROCK活化以及PI3K功能的参与,同时还有其他蛋白质复合物与信号通路参与调控该过程;(5)除电场参数不同之外,细胞本身的衰老情况和培养环境也会对趋电性迁移的结果产生影响。总而言之,电场作为一种影响干细胞迁移特性的重要信号,与其他新兴材料结合在组织工程应用中展现出了一定的潜力,有望在指导干细胞归巢方面发挥更加重要的作用,促进骨组织再生和修复以及神经系统、自身免疫系统以及肿瘤等疾病的研究取得更大的突破。

关键词：干细胞电场趋电性迁移机制归巢效应物理因子电场装置细胞衰老培养环境

基于点云语义分割的猕猴桃冠层叶密度测量方法

在线全文

学校读者我要写书评

暂无评论

农机化研究 2025年第2期47卷 27-35页

作者：韩皓名石复习席新明西北农林科技大学机械与电子工程学院陕西杨凌712100

提出了一种基于LiDAR的猕猴桃果园叶密度测量方法,旨在为猕猴桃果园冠层喷药提供更精确的指导。首先,使用激光雷达扫描10个密度不同的猕猴桃冠层建立点云数据集,利用RandLA-Net神经网络模型并通过6折交叉验证的方法对猕猴桃冠层的树叶... 详细信息

提出了一种基于LiDAR的猕猴桃果园叶密度测量方法,旨在为猕猴桃果园冠层喷药提供更精确的指导。首先,使用激光雷达扫描10个密度不同的猕猴桃冠层建立点云数据集,利用RandLA-Net神经网络模型并通过6折交叉验证的方法对猕猴桃冠层的树叶、树枝和T型架点云进行语义分割;然后,计算仅包含树叶信息的冠层点云表面积,通过与人工落叶后的实测冠层叶属性(叶面积、叶片数)进行回归分析比较,得到冠层叶点云表面积与真实冠层叶属性的关系;最后,将3 m×3 m的猕猴桃冠层区域划分为400个225 cm^(2)的小网格区域,用以生成冠层叶密度图。结果表明:RandLA-Net网络模型能够有效地对猕猴桃冠层的树枝、树叶与T型架点云进行分割,模型平均总体精度OA达到92%以上,平均交并比mIoU为81.4%,冠层实测叶面积与冠层叶点云表面积的回归分析中获得了较高的相关性R=0.78,回归方程为y=1.491x+8315。对于每个猕猴桃冠层点云数据,通过Alpha-shape算法计算网格区域的冠层体积和预测网格真实叶面积的方法生成冠层叶密度图。所开发的基于点云语义分割的猕猴桃冠层叶密度测量方法,各项指标均符合预期要求,可以为果园冠层喷药提供更精准的指导。

关键词：猕猴桃园冠层叶密度点云语义分割深度学习精准喷雾

Evaluation of short-term effects of drug-loaded microspheres and traditional transcatheter arterial chemoembolization in the treatment of advanced liver cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2022年第12期14卷 2367-2379页

作者： Ting Ye shi-han Shao Kan Ji shu-Lin Yao Department of Nuclear Medicine First Medical CenterPLA General HospitalBeijing 100039China Department of Hepatobiliary Surgery The Sixth Medical CenterPLA General HospitalBeijing 100048China Department of Interventional Radiology First Medical CenterPLA General HospitalBeijing 100071China

BACKGROUND Liver cancer is a malignant tumor with high morbidity and *** arterial chemoembolization(TACE)is the main method for surgically unresectable liver *** recent years,drug-loaded microspheres have been gradually applied in TACE *** are some controversies about the therapeutic effects of drug-loaded microspheres TACE(D-TACE)and traditional *** To explore the short-term efficacy of D-TACE and traditional TACE in the treatment of advanced liver *** The clinical data of 73 patients with advanced liver cancer admitted to the First and Sixth Medical Centers of Chinese PLA General Hospital from January 2017 to October 2019 were retrospectively *** them,15 patients were treated with D-TACE,and 58 patients were treated with traditional *** baseline characteristics,perioperative laboratory indices,postoperative adverse reactions and postoperative complications were compared between the two *** There was no statistical difference between the two groups for the postoperative response:The highest postoperative body temperature of the drug-loaded microsphere group was 38.0±0.9℃and the postoperative highest body temperature of the traditional TACE group was 38.3±0.7℃(t=-1.414,P=0.162).For the 24 h postoperative nausea and vomiting after surgery in terms of scoring and postoperative pain scores,the traditional TACE group was higher than the drugloaded microsphere group(χ2=14.33,P=0.014;χ2=32.967,P=0.000)and the two groups had significant statistical *** disease control rate at 3 mo after treatment in the drugloaded microsphere group was 60%and the disease control rate at 3 mo after treatment in the traditional TACE group was 75.9%(χ2=4.091,P=0.252).There was no statistical difference between the two groups of *** the follow-up period,the number of interventional treatments received was once in the drug-loaded microsphere group and the traditional TACE group received an

关键词： Primary liver cancer Hepatocellular carcinoma Drug-loaded microsphere transcatheter arterial chemoembolization Traditional transcatheter arterial chemoembolization Treatment Short-term effica