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Epidemiology and outcome of individuals with intraductal papillary neoplasms of the bile duct

World Journal of Gastrointestinal Oncology 2023年第5期15卷 843-858页

作者： Rong-shou Wu Wen-Jun Liao Jing-Sheng Ma Jia-Kun Wang Lin-Quan Wu ping Hou Department of Hepatobiliary and Pancreatic Surgery The Second Affiliated Hospital of Nanchang UniversityNanchang 330000Jiangxi ProvinceChina Department of Organ Transplantation The Second Affiliated Hospital of Nanchang UniversityNanchang 330000Jiangxi ProvinceChina Department of General Surgery The First Affiliated Hospital of Gannan Medical CollegeNo.23 Qingnian RoadZhanggong DistrictGanzhou 341000Jiangxi ProvinceChina

BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)is a rare distinct subtype of precursor lesions of biliary *** is considered to originate from luminal biliary epithelial cells,typically displays mucin-hypersecretion or a papillary growth pattern,and results in cystic dilatation[1].IPNB develops anywhere in the intrahepatic and extrahepatic biliary tracts,and can occur in various pathological stages from low-grade dysplasia to invasive *** have similar phenotypic changes in the occurrence and development of all subtypes,and the prognosis is significantly better than that of traditional(nonpapillary)*** To evaluate the clinicopathological features of IPNB to provide evidence-based guidance for *** Invasive IPNB,invasive intraductal papillary mucinous neoplasm of the pancreas(IPMN),and traditional cholangiocarcinoma data for affected individuals from 1975 to 2016 were obtained from the Surveillance,Epidemiology,and End Results(SEER)*** percentage changes(APCs)in the incidence and incidence-based(IB)mortality were *** identified the independent predictors of overall survival(OS)and cancer-specific survival(CSS)in indivi duals with invasive *** The incidence and IB mortality of invasive IPNB showed sustained decreases,with an APC of-4.5%(95%CI:-5.1%to-3.8%)and-3.3%(95%CI:-4.1%to-2.6%)(P<0.001),*** decreases in incidence and IB mortality were seen for invasive IPMN but not for traditional *** OS and CSS for invasive IPNB were better than for invasive IPMN and traditional cholangiocarcinoma.A total of 1635 individuals with invasive IPNB were included in our prognosis *** most common tumor sites were the pancreaticobiliary ampulla(47.9%)and perihilar tract(36.7%),but the mucin-related subtype of invasive IPNB was the main type,intrahepatically(approximately 90%).In the univariate and multivariate Cox regression analysis,age,tum

关键词： Surveillance,Epidemiology,and End Results database Intraductal papillary neoplasms of the bile duct Subtype Annual percentage changes Prognosis

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PREPARATION OF Au/SULFONATED POLYSTYRENE CATALYSTS FOR LOW-TEMPERATURE CO OXIDATION

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Chinese Journal of Polymer Science 2001年第5期19卷 503-507页

作者： Shi-hua Wu Xiu-cheng Zheng Wei-ping Huang shou-min Zhang Wei Wei Department of Chemistry, Nankai University Tianjin 300071, China Department of Chemistry Nankai University Tianjin 300071 China

Supported Au catalysts for low-temperature CO oxidation were prepared by solvated metal atom impregnation (SMAI) and conventional impregnation (Cl). X-ray photoelectron spectroscopy (XPS) investigations indicated that the elemental gold in all the samples was in the metallic state, XRD measurements showed that the mean diameters of Au particles prepared by SMAI were smaller than those prepared by Cl with the same gold content. Catalytic tests showed that the SMAI catalyst had higher CO oxidation activity than the CI catalyst with the same compositions. Both SMAI and Cl catalysts exhibited high activity in low temperature CO oxidation. Full CO conversion was obtained at 323-383K.

关键词： CO oxidation gold catalysts solvated metal atom impregnations conventional impregnation sulfonated polystyrene

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Hybrid Estimation of State and Input for Linear Discrete Time-varying Systems： A Game Theory Approach

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自动化学报 2008年第6期34卷 665-669页

作者： YOU Fu-Qiang WANG Fu-Li GUAN shou-ping Key Laboratory of Integrated Automation Process Industry Ministry of Education Northeastern University Shenyang 110004 P. R. China

为线性分离变化时间的系统的 H 混合评价问题在这份报纸被调查，在估计的信号是状态和输入的线性联合的地方。设计目的从骚乱要求最坏的精力获得到是的评价错误不到规定水平。混合评价问题的最佳的答案是僵绳点一二播放器零和微分游戏... 详细信息

为线性分离变化时间的系统的 H 混合评价问题在这份报纸被调查，在估计的信号是状态和输入的线性联合的地方。设计目的从骚乱要求最坏的精力获得到是的评价错误不到规定水平。混合评价问题的最佳的答案是僵绳点一二播放器零和微分游戏。根据微分比赛途径，为混合评价问题的必要、足够的可解决的条件以一个 Riccati 微分方程的答案被提供。而且，如果可解决的条件满足，一个可能的评估者被建议。评估者被印射矩阵的一个获得矩阵和产量描绘，在后者反映在未知输入和输出评价错误之间的内部关系的地方。最后，一个数字例子被提供说明建议途径。

关键词：博奕论线性离散系统时间变化系统智能化系统

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Mapping Daily Temperature and Precipitation in the Qilian Mountains of Northwest China

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Journal of Mountain Science 2014年第4期11卷 896-905页

作者： PENG shou-zhang ZHAO Chuan-yan WANG Xiao-ping XU Zhong-lin LIU Xing-ming HAO Hu YANG Shi-fei State Key Laboratory of Pastoral Agricultural Ecosystem Institute of Arid Agroecology School of Life Sciences Lanzhou University Institute of Arid Meteorology China Meteorological Administration MOE Key Laboratory of Oasis Ecology College of Resource and Environmental Science Xinjiang University Management Bureau of Qilian Mountains National Nature Reserve in Gansu

Daily meteorological data are the critical inputs for distributed hydrological and ecological models. This study modified mountain microclimate simulation model （MTCLIM） with the data from 19 weather stations, and compared and validated two methods （the MTCLIM and the modified MTCLIM） in the Qilian Mountains of Northwest China to estimate daily temperature （i.e., maximum temperature, minimum temperature） and precipitation at six weather stations from i January 2000 to 31December 2009. The algorithm of temperature in modified MTCLIM was improved by constructing the daily linear regression relationship between temperature and elevation, aspect and location information. There are two steps to modify the MTCLIM to predict daily precipitation： firstly, the linear regression relationship was built between annual average precipitation and elevation, location, and vegetation index; secondly, the distance weight for measuring the contribution of each weather station on target point was improved by average wind direction during the rainy season. Several regression analysis and goodness-of-fit indices （i.e., Pearson＇s correlation coefficient, coefficient of determination, mean absolute error, root-mean-square error and modelingefficiency） were used to validate these estimated values. The result showed that the modified MTCLIM had a better performance than the MTCLIM. Therefore, the modified MTCLIM was used to map daily meteorological data in the study area from 2000 to 2009. These results were validated using weather stations with short time data and the predicted accuracy was acceptable. The meteorological data mapped could become inputs for distributed hydrological and ecological models applied in the Qilian Mountains.

关键词： MTCLIM (Mountain microclimatesimulation model) Wind direction Precipitation Temperature Qilian Mountains.

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Effects of the Specific Area and the Thermal Stability of a Polymer on the Catalytic Activities of Polymer Immobilized Co-Pd Catalysts by SAMI

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Chemical Research in Chinese Universities 2001年第4期17卷 439-444页

作者： WU Shi-hua WEI Wei ZHU Chang-ying HUANG Wei-ping ZHANG shou-min ZHENG Xiu-cheng ZHANG Shu-hong ZHAO Wei-jun Department of Chemistry Naikai UniversityTianjin 300071P.R.China

Co-Pd bimetallic catalysts immobilized with four kinds of resins with different specific areas were prepared by means of the solvated metal atom impregnation (SMAI) method. The results of the XRD and the magnetic measurement showed that as the specific area of the resin increased, the particle sizes of Co and Pd on the catalysts with the same metal content decreased, so the catalytic activity of the catalysts for the hydrogenation of diacetone alcohol as well as the reduction of oxygen on the fuel cell electrode increased. Below 140 , the conversion of diacetone alcohol increased as the reaction temperature increased, and above 140 , the conversion decreased because of the rupture of the resin.

关键词： Cobalt-palladium catalyst Diacetone alcohol hydrogenation Fuel cell electrode

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Sonochemical Preparation of Micro- and Nanometer Cu_2O

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Chemical Research in Chinese Universities 2008年第1期24卷 1-3页

作者： WANG Ling ZHANG Xiao-xia YUAN Hong-ming CHEN Yan DONG Zhong-ping PANG Guang-sheng FENG shou-hua State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin University Changchun 130012 P R.. China The First Geologic Survey of Jilin Province Changchun 130031 P R.China Analysis and Test Center Jilin University Chanchun 130021 P R. China

Cu2O particles with different morphologies and scales were prepared sonochemically on the solid-liquid interface of CuCl and water, by adjusting the reaction factors. The products were characterized by powder X-ray diffraction（XRD） and scanning electron microscopy（SEM）. The formation and morphology of Cu2O crystals were influenced by high-intensity ultrasound, reaction temperature, and addition of CuCl. The results indicate that micrometer Cu2O was crystallized in cubic and octahedral shapes, whereas, nanometer Cu2O was not produced in well-shaped crystals.

关键词： Cu2O Ultrasound Morphology CuCl

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Phenolic glycosides from the stems of Homalium stenophyllum

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Chinese Journal of Natural Medicines 2021年第3期19卷 225-230页

作者： WU shou-Yuan BAI Meng ZHOU Qi NONG Xu-Hua CHEN Guang-Ying ZHAO Si-Yu HAN Chang-Ri SONG Xiao-ping Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education Hainan Normal UniversityHaikou 571158China Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province Hainan Normal UniversityHaikou 571158China Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province Hainan Vocational University of Science and TechnologyHaikou 571126China School of Chemistry and Chemical Engineering Lingnan Normal UniversityZhanjiang 524048China

The phytochemical investigation of the stems of Homalium stenophyllum afforded seven new phenolic glycosides(1-5 and 8-9)and two known compounds(6 and 7).Their structures were elucidated by comprehensive analyses of NMR spectroscopic,mass spectrometric data and chemical ***,their anti-inflammatory activities against the NO production in LPS-induced macrophages were evaluated.

关键词： Homalium stenophyllum Phenolic glycosides Chemical hydrolysis Anti-inflammatory activity

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板栗花粉总黄酮提取及HPLC定量

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食品工业科技 2010年第6期31卷 270-272页

作者：武首香包秀萍天津现代职业技术学院天津300222 天津科技大学材料科学与化学工程学院天津300457

对板栗花粉总黄酮提取工艺进行优化,最佳提取条件:提取温度60℃、提取时间1.5h、乙醇浓度80%、液固比(V/m)20:1。HPLC条件:紫外检测波长280nm、柱温30℃、进样量20μL、流速1mL/min、流动相甲醇:水=75:25(V/V),在此色谱条件下HPLC法测... 详细信息

对板栗花粉总黄酮提取工艺进行优化,最佳提取条件:提取温度60℃、提取时间1.5h、乙醇浓度80%、液固比(V/m)20:1。HPLC条件:紫外检测波长280nm、柱温30℃、进样量20μL、流速1mL/min、流动相甲醇:水=75:25(V/V),在此色谱条件下HPLC法测定板栗花粉总黄酮含量为5.00g/100g。

关键词：板栗花粉总黄酮提取高效液相色谱(HPLC)

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A Study of Grain Growth Kinetics in Sintered NdFeB Magnets

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Journal of Rare Earths 2001年第3期19卷 209-213页

作者：刘湘涟何建平董清飞周寿增 Univ Sci & Technol Beijing State Key Lab Adv Met & Mat Beijing 100083 Peoples R China Beijing Hengei Technol Co Ltd Beijing 100080 Peoples R China

The Nd2Fe14 B grain growth kinetics in sintered NdFeB magnets with nominal compositions of Nd30+xDy1.5Fe67.08-xAl0.4B1.02 (%, x = 0, 3) was studied. The grain size parameters were determined by means of the linear intercept method on SEM secondary electron images. It is observed that the grain growth process is more sensitive to sintering temperature than to sintering time although the grain size rises with both sintering temperature and time. It is also found that magnets prepared from the pre-alloy powder with a higher oxygen content exhibit a lower grain growth rate and magnets made from the pre-alloy powder with a broader particle size distribution demonstrate a higher grain growth rate. It is believed that the presence of appropriate amounts of Nd oxides effectively impedes the grain growth process and a larger difference in sizes between pre-alloy powder particles significantly accelerates the grain growth process. On the basis of experimental results, the grain growth exponent and the corresponding activation energy were obtained. A possible grain growth mechanism in NdFeB magnets during sintering was briefly discussed.

关键词： rare earths NdFeB-type magnet sintering grain growth kinetics

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Bone Marrow Urokinase Plasminogen Activator Receptor Levels are Associated with the Progress of Multiple Myeloma

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Chinese Medical Sciences Journal 2016年第3期31卷 155-160页

作者： Li-hong shou Dan Cao Xiao-hui Dong Qiu Fang Bao-lian Xu Ju-ping Fei Department of Hematology Huzhou Central Hospital

Objective To determine the mRNA and protein levels of urokinase plasminogen activator receptors(u PAR) in bone marrow fluid and bone marrow tissue from multiple myeloma(MM) patients and assess association of u PAR level with prognosis of *** u PAR levels in bone marrow fluid of 22 MM patients at the stable and progressive stages and 18 iron deficiency anemia patients with normal bone marrow(control) were examined by ***,u PAR expression in bone marrow tissue was investigated by RT-PCR and Western blot,*** distribution of u PAR in MM cells was examined using immunofluorescence *** pathological changes in different stages of MM patients were studied by HE *** u PAR level in bone marrow fluid of MM patients(1.52±0.32 μg/ml) was found to be higher than that in the control group(0.98±0.15 μg/ml).Interestingly,u PAR protein(0.686±0.075 vs.0.372±0.043,P<0.05) and m RNA(2.51±0.46 vs.4.46±1.15,P<0.05) expression levels of MM patients at the progressive stage were significantly higher than those at the stable *** expression of u PAR in MM bone marrow was confirmed by immunofluorescence ***,HE staining revealed a great increased number of nucleated cells and severe impairment of hematopoietic function in the bone marrow of patients with progressive-stage *** Our study reveals that u PAR expression is positively correlated with the development and progress of MM.

关键词： multiple myeloma urokinase-type plasminogen activator receptor bone marrow urokinase

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