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Critical assessment of the reported bidirectional associations between gallstone, non-alcoholic fatty liver, and kidney stone diseases

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World Journal of Gastroenterology 2025年第5期31卷 133-136页

作者： jing-jing Lu Yuan-Zhi Chen Yuan-peng Huang Department of Internal Medicine Xiamen Hospital of Traditional Chinese MedicineThe Affiliated with Fujian University of Traditional Chinese MedicineXiamen 361015Fujian ProvinceChina The Eighth School of Clinical Medicine Xiamen Hospital Beijing University of Chinese MedicineXiamen 361015Fujian ProvinceChina School of Public Health Xiamen UniversityXiamen 361102Fujian ProvinceChina

The recent article by Jiang et al published in World Journal of Gastroenterology reports substantial bidirectional associations between gallstone disease(GSD),non-alcoholic fatty liver disease(NAFLD),and kidney stone disease(KSD),based on multicenter cross-sectional studies and a systematic review with *** the findings have the potential to significantly impact clinical and pre-ventive strategies,several methodological issues merit closer *** letter critiques key aspects of the study,including sample population hetero-geneity,potential confounding variables,and the reliance on cross-sectional data that may limit causal *** also discuss the generalizability of these results to broader populations given the study's focus on the Chinese *** addressing these concerns,we suggest a more nuanced interpretation of the associations between GSD,NAFLD,and KSD,advocating for longitudinal studies to validate these findings and enhance their applicability in global health contexts.

关键词： Gallstone disease Non-alcoholic fatty liver disease Kidney stone disease Bidirectional associations Meta-analysis

Unsupervised multiplex graph diffusion networks with multi-level canonical correlation analysis for multiplex graph representation learning

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Science China(Information Sciences) 2025年第03期68卷 66-79页

作者： Sichao FU Qinmu peng Yange HE Baokun DU Bin ZOU Xiao-Yuan jing Xinge YOU School of Electronic Information and Communications Huazhong University of Science and Technology Platform Operation and Marketing Center JD Retail Faculty of Mathematics and Statistics Hubei Key Laboratory of Applied Mathematics Hubei University School of Computer Science Wuhan University

In recent years, unsupervised multiplex graph representation learning(UMGRL) has received increasing research interest, which aims to learn discriminative node features from the multiplex graphs supervised by data without the guidance of labels. Although these designed UMGRL methods have obtained great success in various graph-related tasks, most existing UMGRL models still have the following issues: highly depending on complex self-supervised strategies(i.e., data augmentation,pretext tasks, and negative pairs sampling), restricted receptive fields, and only aggregating low-frequency information between nodes. In this paper, we propose a simple unsupervised multiplex graph diffusion network(UMGDN) with the aid of multi-level canonical correlation analysis to solve the above issues. Specifically, we first decouple the feature transform and propagation processes of the graph convolution layer to further improve the generalization of the learnable parameters. And then, we propose adaptive diffusion propagation to capture long-range dependency relationships between nodes, not the local neighborhood interactions. Finally, a multi-level canonical correlation analysis loss on both the feature transform and propagation processes is proposed to maximize the correlation of the same node features from multiple graphs for guiding model optimization. Compared to the existing UMGRL models, our proposed UMGDN does not need to introduce any data augmentation, negative pairs sampling techniques, complex pretext tasks, and also adaptively aggregates the optimal frequency information between nodes to generate more robust node embeddings. Extensive experiments on four popular datasets and two graph-related tasks demonstrate the effectiveness of the proposed method.

关键词： unsupervised multiplex graph representation learning graph neural networks node classification node clustering

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Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO modulation

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong Li Li Dan jing peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Climate-Environment for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 *** results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the *** higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in *** flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through *** occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.

关键词： Carbon variability ENSO modulation CMIP6 models

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High potential in synergizing the reduction of dissolved organic carbon concentration and carbon dioxide emissions for submerged-vegetationcovered river networks

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Journal of Environmental Sciences 2025年第5期151卷 298-309页

作者： Qingqian Li Ruixia Liu Zhangmu jing Yanjie Wei Shengqiang Tu Huibin Yu Hongjie Gao peng Yuan State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental ScienceBeijing 100012China State Environmental Protection Key Laboratory of Estuarine and Coastal Environment Chinese Research Academy of Environmental ScienceBeijing 100012China State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China College of Municipal and Environmental Engineering Shenyang Jianzhu UniversityShenyang 110168China

Various technologies and projects have been explored and developed for the synergetic control of environmental pollution and carbon emissions in aquatic *** submerged vegetation in shallow waters was also expected to achieve this ***,the magnitude and mechanism of carbon dioxide(CO_(2))emission affected by submerged vegetation is not clear enough in complex aquatic *** study investigated the influences of submerged plants on CO_(2)emission,ecosystem metabolism features,and microbial community traits based on observations in river networks on the Changjiang River *** results showed that CO_(2)emission from planted waters accounted for 73%of unplanted ***,planted waters had higher dissolved organic carbon removal capacity in overlying water and higher potential of carbon sequestration in sediment at the same *** distinctions between the two habitats were attributed to(1)improved CO_(2)and bicarbonate consumption in water columns via enhancing photosynthesis and(2)inhibited CO_(2)production by reconstructing the benthic microbial *** eco-advantages were found in planted sediments,such as a high potential of methane oxidation and xenobiotics biodegradation and a low risk of becoming black and *** brief,submerged vegetation is beneficial in promoting pollution removal and carbon retention *** study advances our understanding of the feedback between aquatic metabolism and CO_(2)emission.

关键词： Mitigated CO_(2)emission Submerged vegetation Paired O_(2)-CO_(2)departure Carbon uptake velocity Microbial metabolism pathways The Changjiang River

Rapid detection of colored and colorless macroand micro-plastics in complex environment via near-infrared spectroscopy and machine learning

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Journal of Environmental Sciences 2025年第1期147卷 512-522页

作者： Hui-Huang Zou Pin-jing He Wei peng Dong-Ying Lan Hao-Yang Xian Fan Lü Hua Zhang Institute of Waste Treatment&Reclamation College of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China

To better understand the migration behavior of plastic fragments in the environment,development of rapid non-destructive methods for in-situ identification and characterization of plastic fragments is ***,most of the studies had focused only on colored plastic fragments,ignoring colorless plastic fragments and the effects of different environmental media(backgrounds),thus underestimating their *** address this issue,the present study used near-infrared spectroscopy to compare the identification of colored and colorless plastic fragments based on partial least squares-discriminant analysis(PLS-DA),extreme gradient boost,support vector machine and random forest *** effects of polymer color,type,thickness,and background on the plastic fragments classification were ***-DA presented the best and most stable outcome,with higher robustness and lower misclassification *** models frequently misinterpreted colorless plastic fragments and its background when the fragment thickness was less than 0.1mm.A two-stage modeling method,which first distinguishes the plastic types and then identifies colorless plastic fragments that had been misclassified as background,was *** method presented an accuracy higher than 99%in different *** summary,this study developed a novel method for rapid and synchronous identification of colored and colorless plastic fragments under complex environmental backgrounds.

关键词： Colorless microplastics Near-infrared hyperspectral imaging Plastic identification Partial least squares discriminant analysis Machine learning

An Efficient and Flexible Bifunctional Dual-Band Electrochromic Device Integrating with Energy Storage

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Nano-Micro Letters 2025年第4期17卷 419-434页

作者： Zekun Huang Yutao peng jing Zhao Shengliang Zhang penglu Qi Xianlin Qu Fuqiang Yan Bing Ding Yimin Xuan Xiaogang Zhang Jiangsu Key Laboratory of Electrochemical Energy Storage Technologies College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China Key Laboratory of Thermal Management and Energy Utilization of Aviation Vehicles College of Energy and Power EngineeringNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China Center for Microscopy and Analysis Nanjing University of Aeronautics and AstronauticsNanjing 211106People’s Republic of China

Dual-band electrochromic devices capable of the spectral-selective modulation of visible(VIS)light and near-infrared(NIR)can notably reduce the energy consumption of buildings and improve the occupants’visual and thermal ***,the low optical modulation and poor durability of these devices severely limit its practical ***,we demonstrate an efficient and flexible bifunctional dual-band electrochromic device which not only shows excellent spectral-selective electrochromic performance with a high optical modulation and a long cycle life,but also displays a high capacitance and a high energy recycling efficiency of 51.4%,integrating energy-saving with *** nanowires structure and abundant oxygen-vacancies of oxygen-deficient tungsten oxide nanowires endows it high flexibility and a high optical modulation of 73.1%and 85.3%at 633 and 1200 nm *** prototype device assembled can modulate the VIS light and NIR independently and effectively through three distinct modes with a long cycle life(3.3%capacity loss after 10,000 cycles)and a high energy-saving performance(8.8℃lower than the common glass).Furthermore,simulations also demonstrate that our device outperforms the commercial low-emissivity glass in terms of energy-saving in most climatic zones around the *** windows represent an intriguing potential technology to improve the building energy efficiency.

关键词： Electrochromic Dual-band electrochromic devices Spectral-selective modulation Flexible Energy storage

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Tailoring Cathode-Electrolyte Interface for High-Power and Stable Lithium-Sulfur Batteries

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Nano-Micro Letters 2025年第4期17卷 181-211页

作者： Mengting Liu Ling-Jiao Hu Zhao-Kun Guan Tian-Ling Chen Xin-Yu Zhang Shuai Sun Ruoli Shi Panpan jing peng-Fei Wang Center of Nanomaterials for Renewable Energy State Key Laboratory of Electrical Insulation and Power EquipmentSchool of Electrical EngineeringXi’an Jiaotong UniversityXi’an 710049People’s Republic of China Low-Dimensional Materials and Photo/Electrochemical Technology Lab School of Materials Science and EngineeringShaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic MaterialsShaanxi University of Science&TechnologyXi’an 710021People’s Republic of China

Global interest in lithium-sulfur batteries as one of the most promising energy storage technologies has been sparked by their low sulfur cathode cost,high gravimetric,volumetric energy densities,abundant resources,and environmental ***,their practical application is significantly impeded by several serious issues that arise at the cathode-electrolyte interface,such as interface structure degradation including the uneven deposition of Li_(2)S,unstable cathode-electrolyte interphase(CEI)layer and intermediate polysulfide shuttle ***,an optimized cathode-electrolyte interface along with optimized electrodes is required for overall ***,we comprehensively outline the challenges and corresponding strategies,including electrolyte optimization to create a dense CEI layer,regulating the Li_(2)S deposition pattern,and inhibiting the shuttle effect with regard to the solid-liquid-solid pathway,the transformation from solid-liquid-solid to solid-solid pathway,and solid-solid pathway at the cathode-electrolyte *** order to spur more perceptive research and hasten the widespread use of lithium-sulfur batteries,viewpoints on designing a stable interface with a deep comprehension are also put forth.

关键词： Lithium-sulfur batteries Shuttle effect Cathode-electrolyte interface Structural enhancement Reaction pathway

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LncRNA PCAT6 promotes progression and metastasis of colonic neuroendocrine carcinoma via MAPK pathway

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World Journal of Gastrointestinal Oncology 2025年第2期17卷 163-178页

作者： Fei Wang Hai-Feng Mu Chun Wang Yue Tang Ming-Yuan Si jing peng Department of General Surgery Nanjing Tongren HospitalNanjing 211100Jiangsu ProvinceChina Department of Pathology Nanjing Tongren HospitalNanjing 211100Jiangsu ProvinceChina

BACKGROUND Colonic neuroendocrine carcinomas(NECs)are highly malignant and invasive with poor *** noncoding RNAs(LncRNAs)participate in the tumorigenesis and metastasis of multiple cancers AIM To detect the roles and mechanisms of lncRNA prostate cancer associated transcript 6(PCAT6)in the progression of colonic *** Human NEC and adjacent normal samples were collected for immunohistochemistry staining of CgA and real-time quantitative polymerase chain reaction(RT-qPCR)of PCAT6 mRNA *** xenograft tumor model and lung metastasis model were established in nude *** lung tissues were stained by hematoxylin and eosin to assess pulmonary *** expression of epithelial-mesenchymal transition(EMT)-related markers and pathway-related genes was measured by RT-qPCR and western ***56 expression was assessed by immunofluorescence *** biological functions of PCAT6 were examined by cell counting kit-8,colony formation assays,Transwell assays and wound healing *** interaction between PCAT6 and its potential downstream target was verified by luciferase reporter *** LncRNA PCAT6 was upregulated in human NEC samples and LCC-18 cells,and its high expression was positively correlated with poor prognosis in patients with colonic ***,the expression of PCAT6 was positively associated with the proliferation,migration,invasion,and EMT of LCC-18 ***,PCAT6 facilitated tumor growth,lung metastasis and EMT in ***,PCAT6 promoted the activation of MAPK to enhance the EMT in colonic NEC by targeting *** In conclusion,lncRNA PCAT6 accelerates the process of colonic NEC by activating ERK/p38 MAPK signaling through targeting *** results might provide useful information for exploring the potential therapeutic targets in colonic NEC.

关键词： Colonic neuroendocrine carcinoma lncRNA PCAT6 Metastasis Epithelial-mesenchymal transition MAPK ceRNA

Interface engineering of Pt/CeO2-{100} catalysts for enhancing catalytic activity in auto-exhaust carbon particles oxidation

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Chinese Chemical Letters 2025年第2期36卷 195-200页

作者： peng Zhang Yitao Yang Tian Qin Xueqiu Wu Yuechang Wei jing Xiong Xi Liu Yu Wang Zhen Zhao Jinqing Jiao Liwei Chen State Key Laboratory of Heavy Oil Processing Key Laboratory of Optical Detection Technology for Oil and GasCollege of ScienceChina University of Petroleum School of Chemistry and Chemical In-situ Center for Physical SciencesFrontiers Science Center for Transformative MoleculesShanghai Jiao Tong University School of Chemistry and Chemical Engineering Ningxia University School of Environmental Science and Engineering Yancheng Institute of Technology State Key Laboratory of Chemical Safety SINOPEC Research Institute of Safety Engineering Co.Ltd.

Herein,we fabricate an embedding structure at the interface between Pt nanoparticles （NPs） and CeO2-{100}nanocubes with surface defect sites （CeO2-SDS） through quenching and gas bubbling-assisted membrane reduction *** in-situ substitution of Pt NPs for atomic-layer Ce lattice significantly increases the amount of reactive oxygen species from 133.68μmol/g to 199.44μmol/*** a result,the distinctive geometric structure of Pt/CeO2-SDS catalyst substantially improves the catalytic activity and stability for soot oxidation compared with the catalyst with no quenching process,i.e.,its T50and TOF values are 332°C and 2.915 h-1,*** with the results of experimental investigations and density functional theory calculations,it is unveiled that the unique embedding structure of Pt/CeO2-SDS catalyst can facilitate significantly electron transfer from Pt to the CeO2-{100}support,and induce the formation of interfacial[Ce-Ox-Pt2]bond chains,which plays a crucial role in enhancing the key step of soot oxidation through the dual activation of surface lattice oxygen and molecular *** a fundamental revelation of the interfacial electronic transmission and corresponding modification strategy contributes a novel opportunity to develop high-efficient and stable noble metal catalysts at the atomic level.

关键词： Catalytic oxidation Defective ceria Nanocube Pt NPs Soot particles