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下咽癌内镜手术中预处理喉上动脉的可行性及疗效观察

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中华耳鼻咽喉头颈外科杂志 2024年第2期59卷 127-132页

作者：李仕晟曾诗颖唐青来朱刚才尹丹辉彭霞杨倩杨新明中南大学湘雅二医院耳鼻咽喉头颈外科长沙410011

目的探讨下咽癌经口内镜手术中主动解剖提前凝闭喉上动脉的可行性及对手术的影响。方法选择8个动静脉灌注尸头,将咽喉部离体,在内镜视野下解剖观察喉上动脉入喉位置及走行,总结其解剖特点。选取2018年1月至2019年12月于中南大学湘雅二... 详细信息

目的探讨下咽癌经口内镜手术中主动解剖提前凝闭喉上动脉的可行性及对手术的影响。方法选择8个动静脉灌注尸头,将咽喉部离体,在内镜视野下解剖观察喉上动脉入喉位置及走行,总结其解剖特点。选取2018年1月至2019年12月于中南大学湘雅二医院耳鼻咽喉头颈外科接受经口内镜手术的29例下咽癌患者,均为男性,年龄39~74岁。通过抽签将纳入的患者随机分为观察组(15例)和对照组(14例),观察组术中主动解剖凝闭喉上动脉。比较2组患者在手术时间、出血量、术后并发症、术后无瘤生存率上的差异。采用SPSS 25.0软件进行统计学分析。结果在内镜视野下标本的喉上动脉入喉点约在甲状软骨上缘水平,于梨状窝外侧壁的后1/3处入喉。手术中观察组病例均能在内镜下探查定位到喉上动脉。观察组患者内镜手术时间[(40.00±7.56)min]短于对照组[(48.57±14.06)min],术中出血量[(24.00±8.28)ml]低于对照组[(42.86±15.41)ml],差异均有统计学意义(t=-2.064,P=0.049;t=-4.064,P=0.001)。观察组术后未发生出血,对照组1例术后出血,2组患者术后均无其他并发症发生。在至少36个月的随访时间中2组无瘤生存率差异无统计学意义(P=0.986),2组总无瘤生存率为86.2%。结论下咽癌经口内镜手术中解剖暴露喉上动脉是可行的,提前处理凝闭喉上动脉可以减少术中出血。

关键词：下咽肿瘤经口内镜手术喉上动脉解剖出血

The fate of antibiotic resistance genes in the coastal lagoon with multiple functional zones

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Journal of Environmental Sciences 2023年第6期128卷 93-106页

作者： shisheng li Hui Gao Haibo Zhang Guangke Wei Qin Shu Ruijing li Shuaichen Jin Guangshui Na Yali Shi Laboratory for coastal marine eco-environment process and carbon sink of Hainan provincet/Yazhou Bay Innovation Institute Hainan Tropical Ocean UniversitySanya 572022China National Marine Environmental Monsitoring Center Dalian 116023China College of Marine Ecology and Environment Shanghai Ocean UniversityShanghai 201306China School of Environment Hangzhou Institute for Advanced StudyUCASHangzhou 310024China

Coastal lagoons provide many important services to human society,but their year-round use for aquaculture introduces large amounts of *** contamination of antibiotic resistance genes(ARGs)is therefore of great *** this study,50 ARGs subtypes,two integrase genes(intl1,intl2),and 16S rRNA genes were detected by high-throughput quantitative PCR,and standard curves of all target genes were prepared for *** occurrence and distribution of ARGs in a typical coastal lagoon(XinCun lagoon,China)were comprehensively *** detected 44 and 38 subtypes of ARGs in the water and sediment,respectively,and discuss the various factors influencing the fate of ARGs in the coastal ***-lincosamides-streptogramins B was the primary ARG type,and macB was the predominant *** efflux and antibiotic inactivation were the main ARG resistance *** XinCun lagoon was divided into eight functional *** ARGs showed a distinct spatial distribution owing to the influence of microbial biomass and anthropogenic activity in different functional *** rafts,abandoned fish ponds,the town sewage zone,and mangrove wetlands provided a large quantity of ARGs to the XinCun *** and heavy metals also significantly correlated with the fate of the ARGs,especially NO_(2)^(−)-N and Cu,which cannot be *** is noteworthy that lagoon-barrier systems coupled with persistent pollutant inputs result in coastal lagoons acting as a“buffer pool”for ARGs,which can then accumulate and threaten the offshore environment.

关键词： Coastal lagoon Antibiotic resistance genes High-throughput qPCR Multifunctional zones Influence factors

海南陵水潟湖典型持久性有机污染物的赋存、来源及生态风险

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海洋环境科学 2024年第4期43卷 619-626页

作者：张银天游俊杰王维支利文李十盛李瑞婧高会张晓迪那广水海南热带海洋学院崖州湾创新研究院/海南省近岸海洋生态环境与碳汇重点实验室/生态环境学院海南三亚572022 国家海洋环境监测中心辽宁大连116023

潟湖是天然的养殖场,具有保护海岸、防风避浪等生态功能,但区域内人类活动产生的污染物可能会对环境产生健康威胁,因此,开展污染物赋存研究是维护潟湖生态平衡和保护渔业资源的重要举措。本研究运用高通量分析技术对海南陵水潟湖表层水... 详细信息

潟湖是天然的养殖场,具有保护海岸、防风避浪等生态功能,但区域内人类活动产生的污染物可能会对环境产生健康威胁,因此,开展污染物赋存研究是维护潟湖生态平衡和保护渔业资源的重要举措。本研究运用高通量分析技术对海南陵水潟湖表层水中典型持久性有机污染物(POPs)赋存状况进行分析,结合人类活动及潟湖环境特征探讨了表层水中多环芳烃(PAHs)、有机氯农药(OCPs)和多氯联苯(PCBs)的来源及生态风险。结果显示,陵水潟湖表层水体中ΣPAHs浓度范围为12.19~291.07 ng/L,ΣOCPs浓度范围为17.40~80.79 ng/L,ΣPCBs浓度范围为0.49~2.74 ng/L。ΣPAHs和ΣOCPs受人为活动干扰强烈,浓度呈现沿岸高于潟湖内部的分布趋势。表层水体中PAHs以低环为主(94%),主要来源为燃烧源;OCPs以六氯环己烷(HCHs)为主(42%),提示近期可能存在林丹的输入;PCBs以二氯联苯(37%)为主,可能来源于大气干湿沉降和非故意人为活动。风险熵结果显示,调查区域存在一定的生态风险,PCB206为主要生态风险单体。

关键词：持久性有机污染物潟湖赋存特征来源解析生态风险

扁桃体下极被膜保留的扁桃体切除术在儿童阻塞性睡眠呼吸暂停治疗中的应用

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中国耳鼻咽喉颅底外科杂志 2024年第3期30卷 76-80页

作者：李建华杨倩陈志勇李仕晟符晓湖南中医药高专附属第一医院湖南省直中医院耳鼻咽喉头颈外科湖南长沙412000 中南大学湘雅二医院耳鼻咽喉头颈外科湖南长沙410011

目的观察扁桃体下极被膜保留的扁桃体切除术在儿童阻塞性睡眠呼吸暂停(OSA)中的可行性及优势。方法将2018年8月—2019年12月行扁桃体下极被膜保留扁桃体切除术(91例)与2017年1月—2018年7月行传统扁桃体切除术(100例)治疗儿童OSA患者的... 详细信息

目的观察扁桃体下极被膜保留的扁桃体切除术在儿童阻塞性睡眠呼吸暂停(OSA)中的可行性及优势。方法将2018年8月—2019年12月行扁桃体下极被膜保留扁桃体切除术(91例)与2017年1月—2018年7月行传统扁桃体切除术(100例)治疗儿童OSA患者的临床资料进行回顾性对比分析。比较两组手术时间、术中出血、术后疼痛评分、术后并发症、随访1年的情况。结果两组手术时间及术中出血无明显差异,下极被膜保留组术后第1天、第3天疼痛评分显著低于传统手术组(P<0.05)。术后出血率传统手术组(7/100,7%)高于下极被膜保留组(2/91,2.19%)(P<0.05)。术后随访1年,两组均未出现局部感染及再发扁桃体肥大情况。结论扁桃体下极被膜保留的扁桃体切除术是儿童OSA的一种安全可行的手术方式,可以有效降低术后出血风险及术后疼痛。

关键词：扁桃体切除术阻塞性睡眠呼吸暂停儿童术后出血手术方式

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便捷式高低凳型绝缘平台的研制

电力安全技术 2024年第2期26卷 37-39页

作者：冯积家罗成辉杜联兴吴源雅李世圣海南电网有限责任公司海南海口570203 海南电网有限责任公司儋州供电局海南儋州571700 海南电网有限责任公司三亚变电运检分公司海南三亚572000 海南电网有限责任公司建设分公司海南海口570311

针对高低凳型绝缘平台在使用过程中存在的问题,提出设计一种具备折叠功能和重量检测报警功能的便捷式高低凳型绝缘平台。通过折叠式设计和凳面重量检测报警,解决了高低凳型绝缘平台存放和运输时占地面积大、不便于运输、重量不均衡等问... 详细信息

针对高低凳型绝缘平台在使用过程中存在的问题,提出设计一种具备折叠功能和重量检测报警功能的便捷式高低凳型绝缘平台。通过折叠式设计和凳面重量检测报警,解决了高低凳型绝缘平台存放和运输时占地面积大、不便于运输、重量不均衡等问题,保障了使用过程的安全性和灵活性。

关键词：高低凳型绝缘平台折叠超载报警重量检测

Smart Colorimetric Corn Starch Films Combined with Anthocyanin-Loaded Glutenin-Carboxymethyl Chitosan Nanocomplexes for Freshness Monitoring of Chilled Pork

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Journal of Renewable Materials 2024年第1期12卷 71-87页

作者： Juan Yan Wenchao li Xianfang Zhang shisheng liu College of Food Science and Engineering Hainan UniversityHaikou570100China Engineering Research Center for Utilization of Tropical Polysaccharide Resources Ministry of EducationHaikou570100China

In this study,intelligent,pH-responsive colorimetric films were prepared by encapsulating anthocyanins in nanocomplexes prepared from glutenin and carboxymethyl *** nanocomplexes were added to a corn starch matrix and used in the freshness monitoring of chilled *** effects of anthocyanin-loaded nanocomplexes on the physical,structural,and functional characteristics of the films were *** addition of anthocyanin-loaded nanocomplexes increased the tensile strength,elongation at break,hydrophobicity,and light transmittance of the films while decreasing their water vapor *** is because new hydrogen bonds are formed between the film components,resulting in a more homogeneous and dense *** colorimetric film has a significant color response to pH *** films were used in experiments on the freshness of chilled pork,in which the pH changes with changing freshness *** results show that the colorimetric film can monitor changes in the freshness of chilled pork in real time,where orange,pink,and green represent the fresh,secondary fresh,and putrefied states of pork,***,the intelligent colorimetric film developed in this study has good application potential in the food industry.

关键词： Carboxymethyl chitosan glutenin nanocomplexes anthocyanins pH indicator film chilled pork

Ultrafast transient sub-bandgap absorption of monolayer MoS2

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light(Science & Applications) 2021年第2期10卷 234-242页

作者： Susobhan Das Yadong Wang Yunyun Dai shisheng li Zhipei Sun Department of Electronics and Nanoengineering Aalto University02150 EspooFinland International Center for Young Scientists(ICYS) National Institute for Materials Science(NIMS)TsukubaJapan QTF Centre of Excellence Department of Applied PhysicsAalto UniversityEspooFinland

The light-matter interaction in materials is of remarkable interest for various photonic and optoelectronic applications,which is intrinsically determined by the bandgap of the materials *** extend the applications beyond the bandgap limit,it is of great significance to study the light-matter interaction below the material ***,we report the ultrafast transient absorption of monolayer molybdenum disulfide in its sub-bandgap region from-0.86 pm to 1.4 *** though this spectral range is below the bandgap,we observe a significant absorbance enhancement up to-4.2%in the monolayer molybdenum disulfide(comparable to its absorption within the bandgap region)due to pump-induced absorption by the excited carrier *** different rise times of the transient absorption at different wavelengths indicate the various contributions of the different carrier states(i.e.,real carrier states in the short-wavelength region of~1μm).Our results elucidate the fundamental understanding regarding the optical properties,excited carrier states,and carrier dynamics in the technologically important near-infrared region,which potentially leads to various photonic and optoelectronic applications(e.g„excited-state-based photodetectors and modulators)of two-dimensional materials and their heterostructures beyond their intrinsic bandgap limitations.

关键词： absorption transient monolayer

INTELliGENT CONTROL SYSTEM OF PULSED MAG WELDING INVERTER BASED ON DIGITAL SIGNAL PROCESSOR

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Chinese Journal of Mechanical Engineering 2008年第6期21卷 86-90页

作者： WU Kaiyuan HUANG shisheng WU Shuifeng li Xinglin School of Mechanical Engineering South China University of Technology Guangzhou 510640 China

A fuzzy logic intelligent control system of pulsed MAG welding inverter based on digital signal processor （DSP） is proposed to obtain the consistency of arc length in pulsed MAG welding. The proposed control system combines the merits of intelligent control with DSP digital control. The fuzzy logic intelligent control system designed is a typical two-input-single-output structure, and regards the error and the change in error of peak arc voltage as two inputs and the background time as single output. The fuzzy logic intelligent control system is realized in a look-up table （LUT） method by using MATLAB based fuzzy logic toolbox, and the implement of LUT method based on DSP is also discussed. The pulsed MAG welding experimental results demonstrate that the developed fuzzy logic intelligent control system based on DSP has strong arc length controlling ability to accomplish the stable pulsed MAG welding process and controls pulsed MAG welding inverter digitally and intelligently.

关键词： Pulsed MAG welding inverter Arc length control Fuzzy logic intelligent control Digital signal processor (DSP)

Enhancing stability by tuning element ratio in 2D transition metal chalcogenides

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Nano Research 2021年第6期14卷 1704-1710页

作者： Zhenjia Zhou Tao Xu Chenxi Zhang shisheng li Jie Xu litao Sun libo Gao National Laboratory of Solid State Microstructures School of PhysicsCollaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of EducationSchool of Electronic Science and EngineeringSoutheast UniversityNanjing210096China International Center for Young Scientists(ICYS) National Institute for Materials Science(NIMS)TsukubaIbaraki3050044Japan

Two-dimensional(2D)transition metal chalcogenides(TMCs)are known to be susceptible to the atmosphere,which greatly obscures the intrinsic physical and chemical *** quantitative origin of the instability on the atomic scale has not been well investigated due to the lack of environmentally stable TMCs ***,we find the stability of the grown TMCs is strongly relevant to their initial element ratios,and thus the stoichiometric bonded TMCs have favorable stability,benefitted from the TMCs with controllable *** this study,the degree of structural degradation has been quantitatively defined by the reduced element ratio of chalcogen to metal through the time-dependent characterizations,and the non-stoichiometric ratios in TMCs reveal the atomic lattices with point defects like additive bonds or vacancies *** study not only provides a potential view to fabricate environmentally stable TMCs based devices,but also will bring an effective feasibility of stacking stable vertical heterostructures.

关键词： transition metal chalcogenides stability point defects stoichiometric ratio two-step vapor deposition