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Reoxidation of liquid steel and evolution of inclusions during protective atmosphere electroslag remelting of Ce-containing heat-resistant stainless steel

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Journal of Iron and Steel Research International 2024年第8期31卷 1923-1935页

作者： Yu Zhao Cheng-bin Shi shijun wang Peng Ren Jing Li State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing(USTB)Beijing 100083China

The evolution of Ce-containing inclusions and its correlation with the reoxidation of liquid steel during protective atmosphere electroslag remelting(ESR)of heat-resistant steel were *** reoxidation of liquid steel took place during the ESR,resulting in the oxygen pickup from 0.0014 to 0.0053 wt.%.The inclusions in the consumable electrode,liquid metal pool and remelted ingot are Ce_(2)O_(2)S and Ce_(2)O,inclusions *** inclusions in the remelted ingot are originated from three ways:(I)the original inclusions from the electrode;(Il)the newly formed Ce_(2)O_(2)S and Ce_(2)O_(3) inclusions in the liquid metal pool by reoxidation remaining still in remelted ingot;(IlI)the newly generated Ce2O2S and Ce_(2)O_(3) inclusions during cooling and solidification of liquid *** relative proportions of Ce_(2)O_(3) inclusions in liquid metal pool and remelted ingot are 41% and 76.5%,*** inclusions ranging from 2 to 5μm in the remelted ingot take up 55%,followed by the inclusions smaller than 2μm(43%of total inclusions).The number proportion of the Ce_(2)0,inclusions in the liquid metal pool which were removed by floating up into slag is 1.96×10-5%.

关键词： Non-metallic inclusion Electroslag remelting Rare earth cerium Reoxidation Inclusion evolution

Ischemia-reperfusion injury:molecular mechanisms and therapeutic targets

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Signal Transduction and Targeted Therapy 2024年第2期9卷 558-596页

作者： Meng Zhang Qian Liu Hui Meng Hongxia Duan Xin Liu Jian Wu Fei Gao shijun wang Rubin Tan Jinxiang Yuan The Collaborative Innovation Center Jining Medical UniversityJiningShandong 272067China Clinical Medical College Jining Medical UniversityJiningShandong 272067China Second Clinical Medical College Jining Medical UniversityJiningShandong 272067China Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital and Institutes of Biomedical SciencesFudan UniversityShanghaiChina Institute of Zoology Chinese Academy of SciencesBeijingChina Department of Physiology Basic medical schoolXuzhou Medical UniversityXuzhou 221004China

Ischemia-reperfusion(I/R)injury paradoxically occurs during reperfusion following ischemia,exacerbating the initial tissue *** limited understanding of the intricate mechanisms underlying I/R injury hinders the development of effective therapeutic *** Wnt signaling pathway exhibits extensive crosstalk with various other pathways,forming a network system of signaling pathways involved in I/R *** review article elucidates the underlying mechanisms involved in Wnt signaling,as well as the complex interplay between Wnt and other pathways,including Notch,phosphatidylinositol 3-kinase/protein kinase B,transforming growth factor-β,nuclear factor kappa,bone morphogenetic protein,N-methyl-D-aspartic acid receptor-Ca2+-Activin A,Hippo-Yes-associated protein,toll-like receptor 4/toll-interleukine-1 receptor domain-containing adapter-inducing interferon-β,and hepatocyte growth factor/mesenchymal-epithelial transition *** particular,we delve into their respective contributions to key pathological processes,including apoptosis,the inflammatory response,oxidative stress,extracellular matrix remodeling,angiogenesis,cell hypertrophy,fibrosis,ferroptosis,neurogenesis,and blood-brain barrier damage during I/R *** comprehensive analysis of the mechanisms involved in Wnt signaling during I/R reveals that activation of the canonical Wnt pathway promotes organ recovery,while activation of the non-canonical Wnt pathways exacerbates ***,we explore novel therapeutic approaches based on these mechanistic findings,incorporating evidence from animal experiments,current standards,and clinical *** objective of this review is to provide deeper insights into the roles of Wnt and its crosstalk signaling pathways in I/R-mediated processes and organ dysfunction,to facilitate the development of innovative therapeutic agents for I/R injury.

关键词： therapeutic reperfusion damage

Fabricating bio-inspired high impact resistance carbon nanotube network films for multi-protection under an extreme environment

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Nano Research 2024年第9期17卷 7793-7802页

作者： Mingquan Zhu Kailu Xiao Wei Zhang Xudong Lei Yunxiang Bai shijun wang Peng Zhang Feng Gao Congying wang Wenqiang Xu Huiyong Li Xianqian Wu Chao wang Hui Zhang Luqi Liu Zhong Zhang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Department of Materials Science and Engineering Texas A&M UniversityCollege StationTexas 77840USA Institute of Mechanics Chinese Academy of SciencesBeijing 100190China School of Astronautics Harbin Institute of TechnologyHarbin150001China CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China

The fabrication of light-weight,highly impact-resistant,and energy-absorbent materials is urgently demanded in many facets of the society from body armor to aerospace engineering,especially under an extreme *** nanotubes(CNTs),one of the strongest and toughest materials ever found,also have good conductivity,chemical stability,and thermal stability,etc,making them a competitive candidate as building blocks to help achieve the above *** this work,a kind of CNT network was prepared by using chlorosulfonic acid(CSA)to release the internal stress of super-aligned carbon nanotube films(SA-CNTF)and dendritic polyamide amine(PAMAM)to further introduce multiple hydrogen bonds and interlocking *** fabricated bioinspired carbon nanotube network films(PAMAM@C-CNTF)have a high toughness of 45.97 MJ/m3,showing an increase of 420%compared to neat *** importantly,the anti-impact performance of the films(e.g.,with a maximum specific energy absorption of 1.40 MJ/kg under 80-100 m/s projectile impact)is superior to that of conventional protective materials from steel and Kevlar fiber,and also exceeds that of any other reported carbon-based *** hierarchical energy dissipation mechanism was further revealed through experiment and *** functions including intelligent heating/anti-icing,ultraviolet protection,as well as electromagnetic interference shielding properties make these network films have great potential in practical multi-protection applications,especially under an extreme environment.

关键词： carbon nanotubes composites mechanical properties multi-function

Carbon nanotube films with ultrahigh thermal-shock and thermalshock-fatigue resistance characterized by ultra-fast ascending shock testing

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Nano Research 2024年第8期17卷 6777-6784页

作者： Mingquan Zhu shijun wang Yunxiang Bai Feng Gao Zhenxing Zhu Congying wang Peng Zhang Hao Jin Hui Zhang Luqi Liu Zhiping Xu Xinghong Zhang Fei Wei Zhong Zhang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Department of Engineering Mechanics Tsinghua UniversityBeijing 100084China National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Center for Composite Materials and StructuresHarbin Institute of TechnologyHarbin 150001China CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China

The exploration of material failure behavior not only involves defining its limits and underlying mechanisms but also entails devising strategies for improvement and protection in extreme ***'ve pioneered an advanced multi-scale,high-speed ascending thermal shock testing platform capable of inducing unprecedented heat shocks at rates surpassing 105℃/*** meticulous examination of the thermal shock responses of carbon nanotube(CNT)films,we've achieved remarkable *** employing an innovative macro-scale synchronous tightening and relaxing approach,we've attained a critical temperature differential in CNT films that exceeds an exceptional 2500℃—surpassing any previously reported metric for highperformance,thermal-shock-resistant ***,these samples have demonstrated exceptional resilience,retaining virtually unchanged strength even after enduring 10,000 thermal shock cycles at temperatures exceeding 1000℃.Furthermore,our research has revealed a novel thermal shock/fatigue failure mechanism that fundamentally diverges from conventional theories centered on thermal stress.

关键词： carbon nanotubes failure behavior thermal shock characterization

Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health

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Chinese Journal of Integrative Medicine 2024年第2期30卷 171-180页

作者： ZHAO Wen-xiao wang Tong ZHANG Ya-nan CHEN Qian wang Yuan XING Yan-qing ZHENG Jun DUAN Chen-chen CHEN Lijun ZHAO Hai-jun wang shijun School of Nursing Shandong University of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineJi'nan(250355)China Shandong Co-innovation Center of Classic Traditional Chinese Medicine Formula Shandong University of Traditional Chinese MedicineJi'nan(250355)China College of Traditional Chinese Medicine Shandong University of Traditional Chinese MedicineJinan(250355)China

The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity,type 2 diabetes mellitus,heart failure,and non-alcoholic fatty liver *** extracted from Chinese medicine(CM)can not only alleviate pathological status but also promote health by anti-inflammatory,regulating immunity,lowering blood glucose and lipids,anti-cancer,and *** alterations of gut microbiota composition and metabolism pathways are the potential mechanisms of CM polysaccharides *** addition,they exert functions through gut-organ axis or play an indirect role by synergistic actions with other drugs or components mediated by gut *** review summarizes the molecular mechanisms of CM polysaccharides interacted with intestinal microbial inhabitants as potential prebiotics forpromoting health.

关键词： Chinese medicine polysaccharides gut microbiota short-chain fatty acids lipopolysaccharides gut-organaxis synergistic actions

What are the underlying causes and dynamics of land use conflicts in metropolitan junction areas?A case study of the central Chengdu–Chongqing region in China

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Regional Sustainability 2024年第3期5卷 81-98页

作者： TIAN Junfeng wang Binyan QIU Cheng wang shijun School of Public Policy and Administration Chongqing UniversityChongqing400044China School of Architecture and Urban Planning Chongqing UniversityChongqing400044China School of Geographical Sciences Northeast Normal UniversityChangchun130024China

Land use conflicts(LUCs),as a spatial manifestation of the conflicts in the human-land relationships,have a profound impact on regional sustainable *** China’s metropolitan junction areas(MJAs),the existence of“administrative district economies”has made the issue of LUCs more *** on a case study of the central Chengdu–Chongqing region,we conducted an exploratory spatial data analysis of the evolutionary process of regional ***,structural equation modeling was utilized to analyze the dynamic mechanism of LUCs in MJAs,with a particular emphasis on exploring the influences of administrative *** results showed that from 2010 to 2020,LUCs in the central Chengdu–Chongqing region continued to worsen,and the spatial process conflict and spatial structure conflict indices increased by more than 30.0%.The intensification of LUCs in the central Chengdu–Chongqing region from 2010 to 2020 was mainly the result of the deterioration of conflicts in evaluation units with low conflict *** in China’s metropolitan areas generally presented a circular gradient distribution,weakening from the core to the periphery,but there were some strong isolated conflict zones in the outer *** in China’s MJAs were the result of interactions among multiple factors,e.g.,natural environment,socio-economic development,policy and institutional processes,and administrative boundary *** boundary affected the flow of socio-economic elements,changing the supply-and-demand competition of stakeholders for land resources,consequently exerting an indirect influence on *** study advances the theory of the dynamic mechanism of LUCs,and provides theoretical support for the governance of these conflicts in transboundary areas.

关键词： Land use conflicts Urban agglomerations Administrative boundary Land resources Structural equation modeling(SEM) Central Chengdu-Chongqing region

What are the underlying causes and dynamics of land use conflicts in metropolitan junction areas? A case study of the central Chengdu– Chongqing region in China

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Regional Sustainability 2024年第3期 83-100页

作者： TIAN Junfeng wang Binyan QIU Cheng wang shijun School of Public Policy and Administration Chongqing University School of Architecture and Urban Planning Chongqing University School of Geographical Sciences Northeast Normal University

Land use conflicts(LUCs), as a spatial manifestation of the conflicts in the human-land relationships, have a profound impact on regional sustainable development. For China's metropolitan junction areas(MJAs), the existence of “administrative district economies” has made the issue of LUCs more prominent. Based on a case study of the central Chengdu–Chongqing region, we conducted an exploratory spatial data analysis of the evolutionary process of regional LUCs. Furthermore, structural equation modeling was utilized to analyze the dynamic mechanism of LUCs in MJAs, with a particular emphasis on exploring the influences of administrative boundary. The results showed that from 2010 to 2020, LUCs in the central Chengdu–Chongqing region continued to worsen, and the spatial process conflict and spatial structure conflict indices increased by more than 30.0%. The intensification of LUCs in the central Chengdu–Chongqing region from 2010 to 2020 was mainly the result of the deterioration of conflicts in evaluation units with low conflict levels. LUCs in China's metropolitan areas generally presented a circular gradient distribution, weakening from the core to the periphery, but there were some strong isolated conflict zones in the outer regions. LUCs in China's MJAs were the result of interactions among multiple factors, e.g., natural environment, socio-economic development, policy and institutional processes, and administrative boundary effects. Administrative boundary affected the flow of socio-economic elements, changing the supply-and-demand competition of stakeholders for land resources, consequently exerting an indirect influence on LUCs. This study advances the theory of the dynamic mechanism of LUCs, and provides theoretical support for the governance of these conflicts in transboundary areas.

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The Chinese guideline for management of snakebites

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World Journal of Emergency Medicine 2024年第5期15卷 333-355页

作者： Rongde Lai Shijiao Yan shijun wang Shuqing Yang Zhangren Yan Pin Lan Yonggao wang Qi Li Jinlong wang Wei wang Yuefeng Ma Zijing Liang Jianfeng Zhang Ning Zhou Xiaotong Han Xinchao Zhang Mao Zhang Xiaodong Zhao Guoqiang Zhang Huadong Zhu Xuezhong Yu Chuanzhu Lyu Emergency Department the First Affi liated Hospital of Guangzhou Medical UniversityGuangzhou 510120China School of Public Health Hainan Medical UniversityHaikou 571199China Surgery Department of Traditional Chinese Medicine the Affi liated People’s Hospital of Fujian University of Traditional Chinese MedicineFuzhou 350004China Emergency Department Chongqing University Central Hospital/Chongqing Emergency Medical CenterChongqing 400014China Department of Surgery of Traditional Chinese Medicine Affi liated Hospital of Jiangxi University of Chinese MedicineNanchang 330006China Department of Emergency Medicine the Fifth Affi liated Hospital of Wenzhou Medical University/Lishui Central HospitalLishui Hospital of Zhejiang UniversityLishui 323000China General Surgery Department the First Affi liated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310006China Emergency Department Shengli Clinical Medical College of Fujian Medical UniversityFuzhou 350001China Emergency Department Chongqing University Fuling HospitalChongqing UniversityChongqing 408000China Emergency Department the First Affi liated Hospital of Guangxi Medical UniversityNanning 530021China Emergency Department the Second Affi liated Hospital of Zhejiang University School of MedicineHangzhou 310009China Emergency Department Wuming Hospital of Guangxi Medical UniversityNanning 530021China Emergency Department Central People's Hospital of ZhanjiangZhanjiang 524037China Emergency Department Hunan Provincial People's HospitalChangsha 410005China Emergency Department National Geriatrics Center of Beijing HospitalBeijing 100020China Emergency Department the Fourth Medical Center of the PLA General HospitalBeijing 100048China Emergency Department China-Japan Friendship HospitalBeijing 100029China Emergency Department Peking Union Medical College HospitalBeiJing 100730China Emergency Department Sichuan Academy of Medical Sciences/Sichuan Provincial People's HospitalChengdu 610072China Research Unit of Island Emergency

In 2009,the World Health Organization included snakebite on the list of neglected tropical diseases,acknowledging it as a common occupational hazard for farmers,plantation workers,and others,causing tens of thousands of deaths and chronic physical disabilities every *** guideline aims to provide practical information to help clinical professionals evaluate and treat snakebite *** recommendations are based on clinical experience and clinical research *** guideline focuses on the following topics:snake venom,clinical manifestations,auxiliary examination,diagnosis,treatments,and prevention.

关键词： Snakebite Envenomation Management Prevention

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中国人口流动网络中的语言纽带效应

地理学报 2024年第4期79卷 873-889页

作者：赵梓渝王士君李卓伟韩钟辉青岛大学旅游与地理科学学院青岛266071 东北师范大学地理科学学院长春130024 中国海洋大学管理学院青岛266100

本文利用2019年腾讯人口迁徙与中国语言分布数据,揭示方言相似性对于中国人口流动影响的语言纽带效应,并进一步探究其时空异质性、交通方式异质性、空间距离对其影响的调节作用。研究发现:①方言相似性能够促进中国人口城际流动网络的... 详细信息

本文利用2019年腾讯人口迁徙与中国语言分布数据,揭示方言相似性对于中国人口流动影响的语言纽带效应,并进一步探究其时空异质性、交通方式异质性、空间距离对其影响的调节作用。研究发现:①方言相似性能够促进中国人口城际流动网络的路径形成概率与关系强度,形成了人口流动网络中的语言纽带效应。地理距离和语言距离分别可视为人口流动的显性和隐性空间成本;②语言纽带效应存在时空异质性和交通方式异质性。地区间的方言相似性每增加一个单位,在“春运”和日常阶段下,中国人口流动网络的路径形成概率分别增加47.7%、49.5%,流动强度分别增加17.1%、9.9%。语言纽带效应对于不同汉语方言区、不同交通方式的人口流动的影响存在正负与程度差异,展示出其对于中国人口流动影响的空间差异与地理含义;③语言纽带效应受到空间衰减规律的制约,并且在不同交通方式和时间段下呈现出差异性和复杂性。本文扩展了当前以经济、社会、人口学特征为主要视角的中国人口流动影响因素研究,对于揭示中国人口流动驱动机制具有科学意义,对于多民族融合的中国社会治理和文化多样性保护具有实践价值。

关键词：人口流动 “春运” 汉语方言语言纽带文化纽带中国