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Future Changes in Various Cold Surges over China in CMIP6 Projections

Advances in Atmospheric Sciences 2024年第9期41卷 1751-1768页

作者： Li MA Zhigang wei Xianru LI Shuting wu Key Laboratory of Environmental Change and Natural Disasters of Chinese Ministry of Education Beijing Normal UniversityBeijing 100875China State Key Laboratory of Earth Surface Processes and Resource Ecology(ESPRE) Beijing Normal UniversityBeijing 100875China Academy of Disaster Reduction and Emergency Management Ministry of Emergency Management and Ministry of EducationBeijing 100875China Faculty of Geographical Science Beijing Normal UniversityBeijing 100875China

Cold surges(CSs)often occur in the mid-latitude regions of the Northern Hemisphere and have enormous effects on socioeconomic *** report that the occurrences of CSs and persistent CSs(PCSs)have rebounded since the 1990s,but the trends related to the frequencies of strong CSs(SCSs)and extreme CSs(ECSs)changed from increasing to decreasing after *** highest-ranked model ensemble approach was used to project the occurrences of various CSs under the SSP1-2.6,SSP2-4.5,and SSP5-8.5 *** frequencies of the total CSs show overall decreasing ***,under the SSP1-2.6 scenario,slight increasing trends are noted for SCSs and ECSs in *** circulations that are characterized by an anomalous anticyclonic circulation with a significantly positive 500-hPa geopotential height(Z500)anomaly at high latitudes along with significant negative anomalies in China were favorable for cold air intrusions into *** addition,the frequencies of all CS types under the SPP5-8.5 scenario greatly decreased in the long term(2071-2100),a finding which is thought to be related to negative SST anomalies in the central and western North Pacific,differences in sea level pressure(SLP)between high-and mid-latitude regions,and a weaker East Asian *** terms of ECSs,the decreasing trends observed during the historical period were maintained until 2024 under the SSP1-2.6 *** to the SSP1-2.6 scenario,the Z500 pattern showed a trend of strengthened ridges over the Ural region and northern East Asia and weakened troughs over Siberia(60°-90°E)under the SSP2-4.5 and SSP5-8.5 scenarios,contributing to the shift to increasing trends of ECSs after 2014.

关键词： cold surge “highest-ranked”model ensemble anticyclonic circulation geopotential height China

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Real-time UAV path planning based on LSTM network

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Journal of Systems Engineering and Electronics 2024年第2期35卷 374-385页

作者： ZHANG Jiandong GUO Yukun ZHENG Lihui YANG Qiming shi Guoqing wu Yong School of Electronics and Information Northwestern Polytechnical UniversityXi’an 710129China The Flight Automatic Control Research Institute of AVIC Xi’an 710065China Military Representative Office of Marine wuhan Bureau in Luoyang Area Luoyang 471000China

To address the shortcomings of single-step decision making in the existing deep reinforcement learning based unmanned aerial vehicle(UAV)real-time path planning problem,a real-time UAV path planning algorithm based on long shortterm memory(RPP-LSTM)network is proposed,which combines the memory characteristics of recurrent neural network(RNN)and the deep reinforcement learning *** networks are used in this algorithm as Q-value networks for the deep Q network(DQN)algorithm,which makes the decision of the Q-value network has some *** to LSTM network,the Q-value network can use the previous environmental information and action information which effectively avoids the problem of single-step decision considering only the current ***,the algorithm proposes a hierarchical reward and punishment function for the specific problem of UAV real-time path planning,so that the UAV can more reasonably perform path *** verification shows that compared with the traditional feed-forward neural network(FNN)based UAV autonomous path planning algorithm,the RPP-LSTM proposed in this paper can adapt to more complex environments and has significantly improved robustness and accuracy when performing UAV real-time path planning.

关键词： deep Q network path planning neural network unmanned aerial vehicle(UAV) long short-term memory(LSTM)

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A New Species of the Genus Scincella Mittleman,1950(Squamata:Scincidae)from Sichuan Province,Southwest China

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Asian Herpetological Research 2024年第2期15卷 115-129页

作者： Ruwan JIA Zongyuan GAO Dihao wu Jinlong REN Dechun JIANG wei wu CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610213SichuanChina University of Chinese Academy of Sciences Beijing 100049China

The genus Scincella Mittleman,1950,within the family Scincidae,is a diverse group comprising 39 described *** taxonomy of the genus is complex due to morphological similarities among species,which often obscures the true extent of biodiversity,resulting in several undescribed species requiring further *** China,particularly within the unique ecosystems of the Hengduan Mountains,the diversity of Scincella is notably underestimated,with only 12 species currently *** the present study,we describe a new species of the genus Scincella,Scincella liangshanensis ***.,from Sichuan Province,Southwest *** characteristics and phylogenetic analyses revealed that the putative new species is distinct from all other known *** discovery not only expands the known diversity of Scincella but also emphasizes the inadequacies in our current understanding of herpetological diversity in *** addition of this species to the scientific record highlights the necessity for ongoing biodiversity assessments to uncover hidden species and enhance our understanding of the intricate web of life in one of the world’s biodiversity hotspots.

关键词： morphology phylogeny Scincella liangshanensis sp.nov. taxonomy the Hengduan Mountains

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Paclitaxel-lipid prodrug liposomes for improved drug delivery and breast carcinoma therapy

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Chinese Chemical Letters 2024年第2期35卷 335-340页

作者： Xin wu Xinmei Chen Xinyu Wang Haisheng He Jianming Chen wei wu Key Laboratory of Smart Drug Delivery of MOE School of PharmacyFudan UniversityShanghai 201203China Department of Pharmacy Fujian University of Traditional Chinese MedicineFuzhou 350122China Shanghai wei Er Lab Shanghai 201707China Shanghai Skin Disease Hospital Tongji University School of MedicineShanghai 200443China

Paclitaxel(PTX)is widely applied for the treatment of unresectable and metastasis breast carcinoma as well as other cancers,whereas its efficacy is always impeded by poor *** are one kind of the most successful drug carriers which are capable of solubilizing PTX and improving patients’tolerance owing to excellent biocompatibility and ***,poor compatibility between PTX and liposomes compromises the stability,drug loading and anti-tumor capacity of liposomal *** address this issue,three lipids with various chain lengths,namely,myristic acid(MA,14C),palmitic acid(PA,16C)and stearic acid(SA,18C),were conjugated to PTX via ester bonds and the synthesized prodrugs with high lipophilicity were further formulated into liposomes,*** liposomes show high stability and drug loadings,as well as sustained drug *** chain lengths of lipids are negatively correlated with drug release and enzymatic conversion rates,which further impact the pharmacokinetics,tumor accumulation,and anti-tumor efficacy of liposomal *** rapid nor slow drug release facilitates high tumor accumulation as well as anti-tumor efficacy of *** all liposomes,PTX-PA-loaded liposomes show the longest circulation and highest tumor accumulation of PTX and exert the most potent anti-tumor capacities in vivo,owing to its moderate drug release and enzymatic conversion *** its superior safety,PTX-PA liposomes hold potential for further clinical translation.

关键词： Paclitaxel Lipids Prodrugs Liposomes Drug release Chemotherapy

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Machine learning-assisted efficient design of Cu-based shape memory alloy with specific phase transition temperature

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 773-785页

作者： Mengwei wu wei Yong Cunqin Fu Chunmei Ma Ruiping Liu Department of Materials Science and Engineering China University of Mining&Technology(Beijing)Beijing 100083China Institute for Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China

The martensitic transformation temperature is the basis for the application of shape memory alloys(SMAs),and the ability to quickly and accurately predict the transformation temperature of SMAs has very important practical *** this work,machine learning(ML)methods were utilized to accelerate the search for shape memory alloys with targeted properties(phase transition temperature).A group of component data was selected to design shape memory alloys using reverse design method from numerous unexplored *** modeling and feature modeling were used to predict the phase transition temperature of the shape memory *** experimental results of the shape memory alloys were obtained to verify the effectiveness of the support vector regression(SVR)*** results show that the machine learning model can obtain target materials more efficiently and pertinently,and realize the accurate and rapid design of shape memory alloys with specific target phase transition *** this basis,the relationship between phase transition temperature and material descriptors is analyzed,and it is proved that the key factors affecting the phase transition temperature of shape memory alloys are based on the strength of the bond energy between *** work provides new ideas for the controllable design and performance optimization of Cu-based shape memory alloys.

关键词： machine learning support vector regression shape memory alloys martensitic transformation temperature

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Natural marmatite photocatalyst for treatment of mineral processing wastewater to help zero wastewater discharge

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Journal of Environmental Sciences 2024年第8期142卷 83-91页

作者： Meirong wu wei Sun Xiangsong Meng Jianhua Kang Yue Yang School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

Mineral processing wastewater(MPW)with large discharge and high toxicity affects environmental safety,and the realizing zero discharge of MPW is of great significance for reducing environmental pollution,saving water resources,and promoting the sustainable development of the mining *** this study,we reported natural marmatite(NM)as a low-cost and efficient photocatalyst for the treatment of MPW to help zero wastewater *** photocatalytic activity of NM was evaluated by the removal of total organic carbon(TOC)from MPW under visible-light illumination,and the optimal degradation conditions were *** showed that superoxide free radicals(^(·)O_(2)^(-))were the dominant active species responsible for organic pollutants degradation,and 74.25%TOC removal was obtained after 120 min reaction under the optimum treatment ***,the wastewater treated by NM photocatalysis can be reused in the flotation system without adverse impact on the product *** on these findings,a model of zero wastewater discharge for flotation with the help of photocatalytic treatment was established,it indicated that the water of the whole system can be balanced without affecting the ore dressing index,which showed that visible light-driven photocatalyst has a promising application prospect in the treatment and recycling of industrial wastewater.

关键词： Natural mineral Photocatalysis Industrial wastewater Wastewater recycling Water balance

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Human Expansion-Induced Biodiversity Crisis over Asia from 2000 to 2020

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Research 2024年第2期2023卷 647-658页

作者： Chao Yang Qingquan Li Xuqing Wang Aihong Cui Junyi Chen Huizeng Liu wei Ma Xuanyan Dong Tiezhu shi Fanyi Meng Xiaohu Yan Kai Ding Guofeng wu MNR Key Laboratory for Geo-Environmental Monitoring of Great Bay Area&Guangdong Key Laboratory of Urban Informatics&Shenzhen Key Laboratory of Spatial Smart Sensing and Services Shenzhen UniversityShenzhen 518060China School of Architecture and Urban Planning Shenzhen UniversityShenzhen 518060China College of Civil and Transportation Engineering Shenzhen UniversityShenzhen 518060China Guangdong Laboratory of Artificial Intelligence and Digital Economy(SZ) Shenzhen 518107China Center for Hydrogeology and Environmental Geology China Geological SurveyBaoding 071051China Department of Geography Hong Kong Baptist UniversityHong Kong Special Administrative Region 999077China Faculty of Land Resource Engineering Kunming University of Science and TechnologyKunming 650093China institute for Advanced Study and Tiandu-Shenzhen University Deep Space Joint Laboratory Shenzhen UniversityShenzhen 518060China School of Civil Engineering Chongqing Jjiaotong UniversityChongging 400074China Department of Cil and Environmental Engineering Tohoku UniversitySendai 980-8579Japan School of Artificial Intelligence Shenzhen PolytechnicShenzhen 518055China School of Computer Science and Technology Dongguan University of TechnologyDongguan 523419China

Asia stands out as a priority for urgent biodiversity conservation due to its large protected areas(PAs)and threatened *** the 21st century,both the highlands and lowlands of Asia have been experiencing the dramatic human ***,the threat degree of human expansion to biodiversity is poorly ***,the threat degree of human expansion to biodiversity over 2000 to 2020 in Asia at the continental(Asia),national(48 Asian countries),and hotspot(6,502 Asian terrestrial PAs established before 2000)scales is investigated by integrating multiple large-scale *** results show that human expansion poses widespread threat to biodiversity in Asia,especially in Southeast Asia,with Malaysia,Cambodia,and Vietnam having the largest threat degrees(~1.5 to 1.7 times of the Asian average level).Human expansion in highlands induces higher threats to biodiversity than that in lowlands in one-third Asian countries(most Southeast Asian countries).The regions with threats to biodiversity are present in~75%terrestrial PAs(including 4,866 PAs in 26 countries),and human expansion in PAs triggers higher threat degrees to biodiversity than that in *** findings provide novel insight for the Sustainable Development Goal 15(SDG-15 Life on Land)and suggest that human expansion in Southeast Asian countries and PAs might hinder the realization of *** reduce the threat degree,Asian developing countries should accelerate economic transformation,and the developed countries in the world should reduce the demands for commodity trade in Southeast Asian countries(i.e.,trade leading to the loss of wildlife habitats)to alleviate human expansion,especially in PAs and highlands.

关键词： Human terrestrial integrating

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Identification of LRRC46 as a novel candidate gene for high myopia

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Science China(Life Sciences) 2024年第9期67卷 1941-1956页

作者： Lingxi Jiang Chao Dai Yao wei Bo Zhao Qi Li Zhengzheng wu Liang Zou Zimeng Ye Zhenglin Yang Lulin Huang Yi shi Sichuan Provincial Key Laboratory for Human Disease Gene Study and the Center for Medical Genetics Department of Laboratory MedicineSichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Department of Ophthalmology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences(2019RU026) Sichuan Academy of Medical Sciences&Sichuan Provincial People’s HospitalChengdu 610072China School of Food and Bioengineering Chengdu UniversityChengdu 610106China School of Medicine University of SydneySydney 2050Australia Jinfeng Laboratory Chongging 400000China

High myopia(HM)is the primary cause of blindness,with the microstructural organization and composition of collagenous fibers in the cornea and sclera playing a crucial role in the biomechanical behavior of these *** a previously reported myopic linkage region,MYP5(17q21-22),a potential candidate gene,LRRC46(c.C235T,p.Q79X),was identified in a large Han Chinese ***46 is expressed in various eye tissues in humans and mice,including the retina,cornea,and *** subsequent cell experiments,the mutation(c.C235T)decreased the expression of LRRC46 protein in human corneal epithelial cells(HCE-T).Further investigation revealed that Lrrc46^(-/-)mice(KO)exhibited a classical myopia *** thickness of the cornea and sclera in KO mice became thinner and more pronounced with age,the activity of limbal stem cells decreased,and microstructural changes were observed in the fibroblasts of the sclera and *** performed RNA-seq on scleral and corneal tissues of KO and normal control wild-type(WT)mice,which indicated a significant downregulation of the collagen synthesis-related pathway(extracellular matrix,ECM)in KO *** in vitro studies further indicated that LRRC46,a member of the important LRR protein family,primarily affected the formation of *** study suggested that LRRC46 is a novel candidate gene for HM,influencing collagen protein VⅢ(Col8a1)formation in the eye and gradually altering the biomechanical structure of the cornea and sclera,thereby promoting the occurrence and development of HM.

关键词： high myopia LRRC46 biomechanics collagen protein VⅢ

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Experimental crushing behavior and energy absorption of angular gradient honeycomb structures under quasi-static and dynamic compression

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Defence Technology（防务技术） 2024年第6期36卷 47-63页

作者： Jiachen Li Yuchen wei Hao wu Xingyu Shen Mengqi Yuan State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China Institute of Occupational Health China Academy of Safety Science and TechnologyBeijing 100012China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China

The high variability of shock in terrorist attacks poses a threat to people's lives and properties,necessitating the development of more effective protective *** study focuses on the angle gradient and proposes four different configurations of concave hexagonal honeycomb *** structures'macroscopic deformation behavior,stress-strain relationship,and energy dissipation characteristics are evaluated through quasi-static compression and Hopkinson pressure bar impact *** study reveals that,under varying strain rates,the structures deform starting from the weak layer and exhibit significant interlayer ***,interlayer shear slip becomes more pronounced with increasing strain *** terms of quasi-static compression,symmetric gradient structures demonstrate superior energy absorption,particularly the symmetric negative gradient structure(SNG-SMS)with a specific energy absorption of 13.77 J/cm~*** dynamic impact,unidirectional gradient structures exhibit exceptional energy absorption,particularly the unidirectional positive gradient honeycomb structure(UPG-SML)with outstanding mechanical *** angle gradient design plays a crucial role in determining the structure's stability and deformation mode during *** interlayer separations result in a more pronounced negative Poisson's ratio effect and enhance the structure's energy absorption *** findings provide a foundation for the rational design and selection of seismic protection structures in different strain rate impact environments.

关键词： Negative Poisson's ratio Gradient honeycomb structure Quasi-static compression Dynamic impact Titanium alloy

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High-throughput microfluidic production of carbon capture microcapsules:fundamentals,applications,and perspectives

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International Journal of Extreme Manufacturing 2024年第3期6卷 330-361页

作者： Xiangdong Liu wei Gao Yue Lu Liangyu wu Yongping Chen College of Electrical Energy and Power EngineeringYangzhou UniversityYangzhouJiangsu 225127People’s Republic of China Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education School of Energy and EnvironmentSoutheast UniversityNanjingJiangsu 210096People’s Republic of China Jiangsu Key Laboratory of Micro and Nano Heat Fluid Flow Technology and Energy Application School of Environmental Science and EngineeringSuzhou University of Science and TechnologySuzhouJiangsu 215009People’s Republic of China

In the last three decades,carbon dioxide(CO_(2)) emissions have shown a significant increase from various *** address this pressing issue,the importance of reducing CO_(2) emissions has grown,leading to increased attention toward carbon capture,utilization,and storage *** these strategies,monodisperse microcapsules,produced by using droplet microfluidics,have emerged as promising tools for carbon capture,offering a potential solution to mitigate CO_(2) ***,the limited yield of microcapsules due to the inherent low flow rate in droplet microfluidics remains a *** this comprehensive review,the high-throughput production of carbon capture microcapsules using droplet microfluidics is focused ***,the detailed insights into microfluidic chip fabrication technologies,the microfluidic generation of emulsion droplets,along with the associated hydrodynamic considerations,and the generation of carbon capture microcapsules through droplet microfluidics are *** review highlights the substantial potential of droplet microfluidics as a promising technique for large-scale carbon capture microcapsule production,which could play a significant role in achieving carbon neutralization and emission reduction goals.

关键词： carbon capture microcapsules droplet microfluidic high-throughput production carbon neutralization

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