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A Knowledge-enhanced Two-stage Generative Framework for Medical Dialogue Information Extraction

Machine Intelligence Research 2024年第1期21卷 153-168页

作者： Zefa Hu Ziyi Ni jing shi Shuang Xu Bo Xu School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China institute of Automation Chinese Academy of SciencesBeijing 100190China

This paper focuses on term-status pair extraction from medical dialogues(MD-TSPE),which is essential in diagnosis dia-logue systems and the automatic scribe of electronic medical records(EMRs).In the past few years,works on MD-TSPE have attracted increasing research attention,especially after the remarkable progress made by generative ***,these generative methods output a whole sequence consisting of term-status pairs in one stage and ignore integrating prior knowledge,which demands a deeper un-derstanding to model the relationship between terms and infer the status of each *** paper presents a knowledge-enhanced two-stage generative framework(KTGF)to address the above *** task-specific prompts,we employ a single model to com-plete the MD-TSPE through two phases in a unified generative form:We generate all terms the first and then generate the status of each generated *** this way,the relationship between terms can be learned more effectively from the sequence containing only terms in the first phase,and our designed knowledge-enhanced prompt in the second phase can leverage the category and status candidates of the generated term for status ***,our proposed special status"not mentioned"makes more terms available and en-riches the training data in the second phase,which is critical in the low-resource *** experiments on the Chunyu and CMDD datasets show that the proposed method achieves superior results compared to the state-of-the-art models in the full training and low-re-sourcesettings.

关键词： Medical dialogue understanding information extraction text generation knowledge-enhanced prompt low-resource setting dataaugmentation

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Topography and functional information of plasma membrane

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Science China(Life sciences) 2008年第2期51卷 95-103页

作者： SUN DeLan1, CHEN JianMin1, SONG YanMei1, ZHU ChuanFeng2. PAN GeBo2.& WAN LiJun2.1 Key Laboratory of Photosynthesis and Environmental Molecular Physiology, institute of Botany, chinese academy of sciences, {2. 100093, China 2.institute of chemistry, chinese academy of sciences, beijing 100080, China Key Laboratory of Photosynthesis and Environmental Molecular Physiology Institute of Botany Chinese Academy of Sciences Beijing 100093 Chin

By using atomic force microscope (AFM), the topography and function of the plasmalemma surface of the isolated protoplasts from winter wheat mesophyll cells were observed, and compared with dead protoplasts induced by dehydrating stress. The observational results revealed that the plasma membrane of living protoplasts was in a state of polarization. Lipid layers of different cells and membrane areas exhibited distinct active states. The surfaces of plasma membranes were unequal, and were characterized of regionalisation. In addition, lattice structures were visualized in some regions of the membrane surface. These typical structures were assumed to be lipid molecular complexes, which were measured to be 15.8±0.09 nm in diameter and 1.9±0.3 nm in height. Both two-dimensional and three-dimensional imaging showed that the plasmalemma surfaces of winter wheat protoplasts were covered with numerous protruding particles. In order to determine the chemical nature of the protruding particles, living protoplasts were treated by proteolytic enzyme. Under the effect of enzyme, large particles became relatively looser, resulting that their width was increased and their height decreased. The results demonstrated that these particles were likely to be of protein nature. These protein particles at plasmalemma surface were different in size and unequal in distribution. The diameter of large protein particles ranged from 2.0 to 440 nm, with a central micropore, and the apparent height of them was found to vary from 12.to 40 nm. The diameter of mid-sized protein particles was between 40―60 nm, and a range of 1.8―5 nm was given for the apparent height of them. As for small protein particles, obtained values were 12.40 nm for their diameter and 0.7―2.2.nm for height. Some invaginated pits were also observed at the plasma membrane. They were formed by the endocytosis of protoplast. Distribution density of them at plasmalemma was about 16 pits per 15 μm2. According to their size, we clas

关键词： atomic force microscope winter wheat protoplast plasma membrane surface membrane protein invaginated pits

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Experimental investigation and numerical simulation on the effect of fissure water pressure in vertical sliding surface

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Science China(Technological sciences) 2005年第z1期48卷 53-64页

作者： ZHANG Lei1,2. LI shihai1, LIAN Zhenzhong1,2.& WANG Yuannian1 1. institute of Mechanics,{2.,{2., China 2. Graduate School,{2., beijing 100060, China institute of Mechanics Chinese Academy of Sciences Beijing 100080 China

This paper studies the effect of fissure water pressure in different fractures on the critical angle of landslide by laboratory investigation and numerical simulation in order to understand the mechanisms of fissure water pressure on landslide stability. Laboratory observations show that the effect of fissure water pressure on the critical angle of landslide is little when the distance between water-holding fracture and slope toe is three times greater than the depth of fissure water. These experimental results are also simulated by a three-dimensional face-to-face contact discrete element method. This method has included the fissure water pressure and can accurately calculate the critical angle of jointed slope when fissure water pressure in vertical sliding surface exists. Numerical results are in good agreement with experimental observations. It is revealed that the location of water-holding structural surface is important to landslide stability. The ratio of the distance between water-holding fissure and slope toe to the depth of fissure water is a key parameter to justify the effect of fissure water pressure on the critical angle of landslide.

关键词： jointed rock slope, discrete element method, fracture in vertical sliding surface, model experiment,fissure water pressure.

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Special relativity and theory of gravity via maximum symmetry and localization

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Science China Mathematics 2008年第4期51卷 568-603页

作者： GUO HanYing institute of Theoretical Physics chinese {2. of sciences beijing 100080 China institute of Theoretical Physics Chinese Academy of Sciences Beijing China

Like Euclid, Riemann and Lobachevski geometries are on an almost equal footing, based on the principle of relativity of maximum symmetry proposed by Professor Lu Qikeng and the postulate on invariant universal constants c and R, the de Sitter/anti-de Sitter (dS/AdS) special relativity on dS/AdS-space with radius R can be set up on an almost equal footing with Einstein’s special relativity on the Minkowski-space in the case of R→∞.Thus the dS-space is coin-like: a law of inertia in Beltrami atlas with Beltrami time simultaneity for the principle of relativity on one side, and the proper-time simultaneity and a Robertson-Walker-like dS-space with entropy and an accelerated expanding S 3 fitting the cosmological principle on another side.If our universe is asymptotic to the Robertson-Walker-like dS-space of R ? (3/Λ)1/2. it should be slightly closed in O(Λ) with entropy bound S ? 3πc 3 k B /ΛG?. Contrarily, via its asymptotic behavior, it can fix on Beltrami inertial frames without ‘an argument in a circle’ and acts as the origin of inertia.There is a triality of conformal extensions of three kinds of special relativity and their null physics on the projective boundary of a 5-d AdS-space, a null cone modulo projective equivalence [ $ \mathcal{N} $ ] ? ? P (AdS 5). Thus there should be a dS-space on the boundary of S 5 × AdS 5 as a vacuum of supergravity.In the light of Einstein’s ‘Galilean regions’, gravity should be based on the localized principle of relativity of full maximum symmetry with a gauge-like dynamics. Thus, this may lead to the theory of gravity of corresponding local symmetry. A simple model of dS-gravity characterized by a dimensionless constant g ?(ΛG?/3c 3)1/2.～ 10?61 shows the features on umbilical manifolds of local dS-invariance. Some gravitational effects out of general relativity may play a role as dark matter.The dark universe and its asymptotic behavior may already indicate that the dS special relativity and dS-gravity be the foundati

关键词： special relativity de Sitter invariance gravity local de Sitter invariance umbilical manifold 83A05 83D05 53A35 53B50

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ON THE CENTRAL RELAXING SCHEMES I:SINGLE CONSERVATION LAWS

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Journal of Computational Mathematics 2000年第3期18卷 313-324页

作者： Hua-zhong Tang (LSEC, institute of Computational Mathematics and Scientific /Engineering Computing, academy of Mathematics and System {2., chinese academy of sciences, beijing, 100080, China) 中科院计算数学与科学工程计算所科学与工程计算国家重点实验室北京 100080

Presents a central relaxing scheme for scalar conservation laws. Details on the preliminary equations; Properties of the relaxed schemes; Conclusions.

关键词： hyperbolic conservation laws the relaxing scheme TVD cell entropy inequality

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ARCHITECTURE OF LADDER,TUBULAR AND SIEVE-PLATE POLYMERS PREPARED BY STEPWISE COUPLING POLYMERIZATION

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chinese Journal of Polymer Science 2000年第3期18卷 195-206页

作者： Rong-ben Zhang Ping Xie Dao-rong Dai Chun-qing Liu institute of chemistry,{2., beijing 100080, China 中科院化学所北京

'Stepwise-coupling polymerization' (SCP) is a very useful approach for preparing microstructure-controllable ordered network polymers, including soluble one-dimensional ladderlike polymers (LP) and tubular polymers (TP), and two-dimensional sieve-plate polymers. The novel reactive LPs are important precursors of micro-structure controllable polymers such as 'fishbone-' or 'rowboat-' like mesomorphic polymers and their metal complexes as well as tubular polymers (TPs). They are full of great potential for use as advanced materials.

关键词： stepwise coupling polymerization ladder polysiloxane tubular polymers

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Modeling of elastic wave propagation on a curved free surface using an improved finite-difference algorithm

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Science China(Physics,Mechanics & Astronomy) 2004年第5期47卷 633-648页

作者： WANG Xiuming1,3 & ZHANG Hailan2.1. CSIRO Petroleum, ARRC, PO BOX 1130, Technology Park, Bentley, WA 6102. Australia 2. institute of Acoustics, chinese academy of sciences,{2., China 3. Present address: institute of Acoustics, chinese academy of sciences,{2., China CSIRO Petroleum ARRC Bentley Australia institute of Acoustics Chinese Academy of Sciences Beijing China

Based on existing direct and imaging methods of a staggered finite-difference scheme, an improved algorithm for staggered finite-difference is proposed to implement rugged topographic free boundary conditions. This method assumes that the free surface can be implemented with horizontal and vertical free surface segments and their corners; the free surface passes through the grid points of shear stress components, instead of the normal stress components. Imaging is carried out for stress components in both horizontal and vertical directions, thus increasing the accuracy. To update particle- velocities, imaging and updating are first performed in the horizontal direction, and then in the vertical direction. The numerical results for elastic flat horizontal free surface with the imaging method and those for flat free surfaces of various slope angles with the proposed method are compared, and are shown to be in good agreement. The advantage of the proposed method is that only the stresses are dealt with in implementing the free surface into the staggered algorithm, which improves computation efficiency.

关键词： elastic wave simulation, curved free surface, staggered finite-difference, algorithm stability.

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A Glance at the Middleware Technology

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Wuhan University Journal of Natural sciences 2001年第Z1期6卷 351-354页

作者： Zhong Cui\|hao institute of Software, chinese academy of sciences,{2., China institute of Software Chinese Academy of Sciences Beijing China

After describing the concept of middleware,this paper discusses the position and value of middleware among modern software technologies,summarizes some kinds of common *** paper also gives some proposals for developin... 详细信息

关键词： middleware software development technology middleware model

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Cleaning of Chromate Manufacture Process

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International Journal of Minerals,Metallurgy and Materials 2000年第2期14卷 132-134页

作者： Xing Zou Yi Zhang(Applied Science School, University of Science and Technology beijing, beijing 100083, China)({2. of Engineering chemistry and Metallurgy, chinese academy of sciences, beijing 100080, China) Applied Science School University of Science and Technology Beijing Beijing 100083 China institute of Engineering chemistry and Metallurgy Chinese Academy of Sciences Beijing 100080 China

Sodium chromate solubility is determined in the range of NaOH concentrations from 450 to 810 g/L andsolution temperatUres from 30 to 110℃. The optimized conditions to separate sodium chromate from NaOH inleached solution are resolved. It is first found the method to efficiently separate sbdium chromate from NaOH andsodium altuninate in crude sodium chromate. Bench-scale studies on the separating are performed. Finally, goodseparation results are achieved.

关键词： chromate separation clean process

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Synthesis of Monoclinic Form of Gd_(2.x)Na_xCuO_4 by Direct Precipitation from Molten Salt

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chinese Chemical Letters 2000年第2期11卷 185-188页

作者： Lin ZHANG Liang Zhong ZHAO Jin Biao ZHANG Cui Ying XU shi Hong LIU (institute of {2.,{2., beijing, 100080) institute of chemistry Chinese Academy of Sciences Beijing 100080 China

A new phase of Gd_(2.x)Na_xCuO_4 was synthesized by direct precipitation from the mixture of Gd_2._3 and CuO in the molten KOH/NaOH/KNO_3 solution at temperature as low as 2.0℃. The resulting precipitate was characterized by using SEM, XRD, EDX, XPS and magnetic method. The XRD data indicate that the precipitated Gd_(2.x)Na_xCuO_4 is monoclinic with lattice parameters a=8.6816, b=3.72.3. c=6.0796. a=γ=90', 0=108.75° and V=186. 13.

关键词： Chemical synthesis gadolinium cuprate monoclinic phase.

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