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Historical Changes and Multi-scenario Prediction of Land Use and Terrestrial Ecosystem Carbon Storage in China

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Chinese Geographical Science 2024年第3期34卷 487-503页

作者： AN Yue TAN Xuelan REN Hui LI Yinqi zhou zhou College of Resources Hunan Agricultural UniversityChangsha 410128China School of Geographic Science Hunan Normal UniversityChangsha 410081China

Terrestrial carbon storage(CS)plays a crucial role in achieving carbon balance and mitigating global climate *** study employs the Shared Socioeconomic Pathways and Representative Concentration Pathways(SSPs-RCPs)published by the Intergovernmental Panel on Climate Change(IPCC)and incorporates the Policy Control Scenario(PCS)regulated by China’s land management *** Future Land Use Simulation(FLUS)model is employed to generate a 1 km resolution land use/cover change(LUCC)dataset for China in 2030 and *** on the carbon density dataset of China’s terrestrial ecosystems,the study analyses CS changes and their relationship with land use changes spanning from 1990 to *** findings indicate that the quantitative changes in land use in China from 1990 to 2020 are characterised by a reduction in the area proportion of cropland and grassland,along with an increase in the impervious surface and forest *** changing trend is projected to continue under the PCS from 2020 to *** the SSPs-RCPs scenario,the proportion of cropland and impervious surface predominantly increases,while the proportions of forest and grassland continuously *** loss in China’s carbon storage from 1990 to 2020 amounted to 0.53×10^(12)kg,primarily due to the reduced area of cropland and *** the SSPs-RCPs scenario,more significant carbon loss occurs,reaching a peak of8.07×10^(12)kg in the SSP4-RCP3.4 *** loss is mainly concentrated in the southeastern coastal area and the Beijing-TianjinHebei(BTH)region of China,with urbanisation and deforestation identified as the primary *** the future,it is advisable to enhance the protection of forests and grassland while stabilising cropland areas and improving the intensity of urban *** research findings offer valuable data support for China’s land management policy,land space optimisation,and the achievement of dual-carbon targets.

关键词： land use change Future Land Use Simulation(FLUS)model carbon storage carbon density dataset land use scenario China

Numerical investigations of focused wave interact with a moving cylinder

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Journal of Hydrodynamics 2023年第4期35卷 724-735页

作者： Yuan Zhuang Fu-chang zhou Wen-jun zhou De-cheng Wan Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Wuhan Second ship Design and Research Institute Wuhan430205China Marine Design and Research Institute of China Shanghai200011China

This paper presents a numerical study on focused wave and current interactions with a *** cylinder is moving in the opposite direction to the wave *** effective computational decomposition method is adopted to reduce the calculation resources.A potential solver high-order spectral(HOS)method is applied to generate focused wave field,while our in-house computational fluid dynamics(CFD)solver naoe-FOAM-SJTU with overset grid takes the charge of achieving the viscous effect around the moving *** viscous domain moving with the cylinder thus the size and mesh grids in computational domain is greatly *** pressure on cylinder surface and wave fields around cylinder are compared with experimental data,shows a well ***,the scattering wave field and vortex shedding are *** the existence of moving cylinder,the classical scattering wave types are still observed.

关键词： Focused wave moving cylinder naoe-FOAM-SJTU solver computational decomposition method

A brief introduction to weakly supervised learning

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National Science Review 2018年第1期5卷 44-53页

作者： Zhi-Hua zhou National Key Laboratory for Novel Software Technology Nanjing University

Supervised learning techniques construct predictive models by learning from a large number of training examples, where each training example has a label indicating its ground-truth output. Though current techniques have achieved great success; it is noteworthy that in many tasks it is difficult to get strong supervision information like fully ground-truth labels due to the high cost of the data-labeling process. Thus,it is desirable for machine-learning techniques to work with weak supervision. This article reviews some research progress of weakly supervised learning, focusing on three typical types of weak supervision:incomplete supervision, where only a subset of training data is given with labels; inexact supervision, where the training data are given with only coarse-grained labels; and inaccurate supervision, where the given labels are not always ground-truth.

关键词： machine learning weakly supervised learning supervised learning

Ruxolitinib add-on in corticosteroid-refractory graft-vs-host disease after allogeneic stem cell transplantation:Results from a retrospective study on 38 Chinese patients

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World Journal of Clinical Cases 2020年第6期8卷 1065-1073页

作者： Si-Hua Dang Qin Liu Rong Xie Na Shen Shu zhou Wei shi Wen Liu Ping Zou Yong You Zhao-Dong Zhong Department of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina Department of Oncology Luohe Central HospitalLuohe 462300Henan ProvinceChina Department of Gynecology and Obstetrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

BACKGROUND Graft-vs-host disease (GVHD) is a major cause of mortality after allogeneic hematopoietic stem cell *** patients have steroid-refractory(SR) *** To evaluate the effect and safety of ruxolitinib add-on in the treatment of patients with SR acute (a) and chronic (c) *** We retrospectively analyzed 38 patients administered ruxolitinib add-on to standard immunosuppressive therapy for SR-aGVHD or SR-cGVHD following allogeneic hematopoietic stem cell *** was administered5-10 mg/d depending on disease severity,patient status,and the use of antifungal *** response rate,time to best response,malignancy relapse rate,infection rate,and treatment-related adverse events were *** The analysis included 10 patients with SR-aGVHD (gradeⅢ/Ⅳ,n=9) and 28patients with SR-cGVHD (moderate/severe,n=24).For the SR-aGVHD and SRcGVHD groups,respectively:Median number of previous GVHD therapies was 2(range:1-3) and 2 (1-4);median follow-up was 2.5 (1.5-4) and 5 (1.5-10) mo;median time to best response was 1 (0.5-2.5) and 3 (1-9.5) mo;and overall response rate was 100%(complete response:80%) and 82.1%(complete response:10.7%) with a response observed in all GVHD-affected *** malignancy relapse rates for the SR-aGVHD and SR-cGVHD groups were 10.0%and 10.7%,*** rates for cytomegalovirus,Epstein-Barr virus,and varicella-zoster virus,respectively,were 30.0%,10.0%,and 0%for the SR-aGVHD group and 0%,14.3%,and 7.1%for the SR-cGVHD *** Ruxolitinib add-on was effective and safe as salvage therapy for SR-GVHD.

关键词： Graft-vs-host disease Graft-vs-leukemia effect Allogeneic hematopoietic stem cell transplantation Ruxolitinib Treatment Antifungal drugs

Simulation of urban expansion using geographical similarity transition rules and neighbourhood sizes

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Journal of Geographical Sciences 2024年第7期34卷 1394-1414页

作者： LI Yinqi AN Yue zhou zhou REN Hui TAN Xuelan College of Resources Hunan Agricultural UniversityChangsha410128China College of Geographical Sciences Hunan Normal UniversityChangsha410081China

Most existing cellular automata(CA)models impose strict requirements on the number and spatial distribution of *** makes it a challenge to capture spatial heterogeneity in urban dynamics and meet the modeling needs of large and complex geographic *** paper presents a CA model based on geographically optimal similarity(GOS)transition rules and similarly sized neighborhoods(SSN).By comparing the similarity in geographical configuration between samples and predicted points,the model enables a comprehensive characterization of the driving mechanism behind urban expansion and its self-organizing *** helps to mitigate the impact of sample selection and assumptions about spatial stationarity on simulation *** performance of GOS-SSN-CA simulation was tested by taking the urban expansion in the Changsha-Zhuzhou-Xiangtan urban agglomeration in China as an *** results show that GOS can derive more accurate and reliable urban transition rules with fewer samples,thereby significantly reducing spatial prediction errors compared with logistic ***,SSN selects different neighborhood sizes to represent the difference between the local self-organizing range and surrounding cells,thus further improving the simulation accuracy and restricting urban expansion ***,GOS-SSN-CA effectively characterizes the geographical similarity of urban expansion,improves simulation accuracy while constraining the urban expansion form,and enhances the practical application value of CA.

关键词： urban growth cellular automata geographic similarity model optimization spatial nonstationarity

Function of FEZF1 during early neural differentiation of human embryonic stem cells

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Science China(Life Sciences) 2018年第3期61卷 35-45页

作者： Xin Liu Pei Su Lisha Lu Zicen feng Hongtao Wang Jiaxi zhou State Key Laboratory of Experimental Hematology Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Center for Stem Cell Medicine Chinese Academy of Medical Sciences & Department of Stem Cells and Regenerative Medicine Peking Union Medical College

The understanding of the mechanism underlying human neural development has been hampered due to lack of a cellular system and complicated ethical issues. Human embryonic stem cells (hESCs) provide an invaluable model for dissecting human development because of unlimited self-renewal and the capacity to differentiate into nearly all cell types in the human body. In this study,using a chemical defined neural induction protocol and molecular profiling, we identified Fez family zinc finger 1 (FEZF1) as a potential regulator of early human neural development. FEZF1 is rapidly up-regulated during neural differentiation in hESCs and expressed before PAX6, a well-established marker of early human neural induction. We generated FEZF1-knockout H1 hESC lines using CRISPR-CAS9 technology and found that depletion of FEZF1 abrogates neural differentiation of hESCs. Moreover,loss of FEZF1 impairs the pluripotency exit of hESCs during neural specification, which partially explains the neural induction defect caused by FEZF1 deletion. However, enforced expression of FEZF1 itself fails to drive neural differentiation in hESCs,suggesting that FEZF1 is necessary but not sufficient for neural differentiation from hESCs. Taken together, our findings identify one of the earliest regulators expressed upon neural induction and provide insight into early neural development in human.

关键词： FEZF1 hESCs CRISPR/Cas9 neural differentiation

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Rehearsal:learning from prediction to decision

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Frontiers of Computer Science 2022年第4期16卷 1-3页

作者： Zhi-Hua zhou National Key Laboratory for Novel Software Technology Nanjing UniversityNanjing210023China

Machine learning[1]studies focus mostly on prediction,where a model is built from a set of observational data formaking correct predictions on unseen *** has beenaddressed very well by modem techniques such as deeplea... 详细信息

关键词： such has see

Bibliometric analysis of randomized controlled trials of colorectal cancer over the last decade

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World Journal of Clinical Cases 2020年第14期8卷 3021-3030页

作者： Chen-Yu Wang shi-Can zhou Xing-Wang Li Bing-Hui Li Jun-Jie Zhang Zheng Ge Quan Zhang Jun-Hong Hu Department of Anorectal Surgery Huaihe HospitalHenan UniversityKaifeng 47500Henan ProvinceChina

BACKGROUND Colorectal cancer is one of the most common cancers *** China,its prevalence ranks fourth and fifth among females and males,***,treatment of rectal cancer follows a multidisciplinary comprehensive treatment approach involving surgery,radiotherapy,chemotherapy,and targeted *** deepening theoretical and molecular research on colorectal cancer,randomized controlled trials(RCTs)on colorectal cancer have made significant ***,many RCTs have *** To investigate the RCTs of global colorectal cancer spanning from 2008 to *** provide suggestions for conducting Chinese RCTs of colorectal *** PubMed and Web of Science databases were searched to obtain RCTs of colorectal cancer carried out between January 1,2008,and January 1,*** bibliometric method was used for statistical analysis of the publication years,countries/regions,authors,institutions,source journals,quoted times,key words,and *** Colorectal cancer RCTs showed an upward trend between 2008 to 2018;the top 10 research institutions in the included literature were from the United States,the United Kingdom,and other countries with a high incidence of colorectal *** of the related research journals are sponsored by European and American *** 15 most cited studies involved international multicenter clinical research,having few participants from Chinese research *** visualization using key words showed that RCTs on colorectal cancer focus on screening,disease-free survival,drug treatment,surgical methods,clinical trials,quality of life,and *** result of the coauthorship network analysis showed that Chinese researchers are less involved in international exchanges compared to those from leading publication *** High-quality RCTs are increasingly favored by leading international ***,there is still a large gap in clinical research between China and leading c

关键词： Colorectal cancer Randomized controlled trial Bibliometrics China

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环境监管的他国镜鉴与对策选择

改革 2015年第4期 58-68页

作者：周适国家发展和改革委员会经济研究所北京100038

我国现阶段环境污染形势日益严峻,环境监管未能有效遏制环境污染。其主要原因在于:法律法规难以发挥惩戒作用,监管政策出台受制于部门利益,垂直与属地监管模式面临重大障碍,监管执法缺乏资源保障,监管工具运用缺乏制度支撑,公众参与作... 详细信息

我国现阶段环境污染形势日益严峻,环境监管未能有效遏制环境污染。其主要原因在于:法律法规难以发挥惩戒作用,监管政策出台受制于部门利益,垂直与属地监管模式面临重大障碍,监管执法缺乏资源保障,监管工具运用缺乏制度支撑,公众参与作用甚微。为使环境监管有效发挥作用,应借鉴国际经验,强化依法处罚和问责力度,优化政策制定方法和过程,强化垂直监管并改进属地监管,加大监管资源向基层倾斜的力度,改进监管工具及其制度保障,提高环境监管的公众参与度。

关键词：环境污染环境监管生态文明