检索结果-南通市图书馆

Acta Mechanica Solida Sinica 2015年第3期28卷 305-312页

作者： Dihua Tong Xueren wu AVIC Beijing Institute of Aeronautical Materials

A radial crack emanating from a semi-circular notch is of significant engineering importance. Accurate determination of key fracture mechanics parameters is essential for damage tolerance design and fatigue crack growth life predictions. The purpose of this paper is to provide an efficient and accurate closed-form weight function approach to the calculation of crack surface displacements for a radial crack emanating from a semi-circular notch in a semi-infinite plate. Results are presented for two load conditions： remote applied stress and uniform stress segment applied to crack surfaces. Based on a correction of stress intensity factor ratio, highly accurate analytical equations of crack surface displacements under the two load conditions are developed by fitting the data obtained with the weight function method. It is demonstrated that the wu- Carlsson closed-form weight functions are very efficient, accurate and easy-to-use for calculating crack surface displacements for arbitrary load conditions. The method will facilitate fatigue crack closure and other fracture mechanics analyses where accurate crack surface displacements are required.

关键词： radial crack semi-circular notch Dugdale strip-yield model crack surface displacement weight function method

3-to 24-month Follow-up on COVID-19 with Pulmonary Tuberculosis Survivors after Discharge:Results from a Prospective,Multicenter Study

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2022年第12期35卷 1091-1099页

作者： WANG Jing Ya ZONG Xing Yu wu Gui Hui QI Yuan Lin LI Hui Zhen JI Xin Yu TONG Lin ZHANG Lei YANG Ming Bo YANG Pu Ye LI Ji Ke XIAO Fu Rong ZHANG Lin Song HU Yun Hong LIU Hong De XU Shou fang SUN Sheng wu Wei MAO Ya LI Min Qing HOU Hao Hua GONG Zhao Yuan GUO Yang JIAO Li Wen QIN Jin WANG Ding Yi WANG fang GUAN Li LIN Gang MA Yan WANG Yan Ping shi Nan Nan Community Health Service Management Center Dongcheng DistrictBeijing 100700China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Public Health Clinical Center of Chengdu Chengdu 610066SichuanChina Yiyuan TCM Hospital Zibo 256199ShandongChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China Xi’an Eighth Hospital Xi’an 710000ShaanxiChina Harbin Infectious Disease Hospital Harbin 150000HeilongjiangChina Hospital(T.C.M)Affiliated to Southwest Medical University Luzhou 646000SichuanChina Xingtai Hospital of Chinese Medicine Xingtai 054000HebeiChina shijiazhuang Fifth Hospital Shijiazhuang 050000HebeiChina Jiamusi Infectious Disease Hospital Jiamusi 154000HeilongjiangChina Chengde Hospital of Traditional Chinese Medicine Chengde 067040HebeiChina Hanzhong Central Hospital Hanzhong 723000ShaanxiChina Ankang Hospital of Traditional Chinese Medicine Ankang 725000ShaanxiChina Department of Traditional Chinese medicine Dazhou Central HospitalDazhou 635000SichuanChina China National Medicines Corporation Ltd Beijing 100077China Beijing University of Chinese Medicine Beijing 101121China Infectious Disease Hospital of Heilongjiang Province Harbin 150030HeilongjiangChin

Objective Coronavirus disease 2019(COVID-19)and tuberculosis(TB)are major public health and social issues *** long-term follow-up of COVID-19 with pulmonary TB(PTB)survivors after discharge is *** study aimed to comprehensively describe clinical outcomes,including sequela and recurrence at 3,12,and 24 months after discharge,among COVID-19 with PTB *** From January 22,2020 to May 6,2022,with a follow-up by August 26,2022,a prospective,multicenter follow-up study was conducted on COVID-19 with PTB survivors after discharge in 13 hospitals from four provinces in *** outcomes,including sequela,recurrence of COVID-19,and PTB survivors,were collected via telephone and face-to-face interviews at 3,12,and 24 months after *** Thirty-two COVID-19 with PTB survivors were *** median age was 52(45,59)years,and 23(71.9%)were *** them,nearly two-thirds(62.5%)of the survivors were moderate,three(9.4%)were severe,and more than half(59.4%)had at least one comorbidity(PTB excluded).The proportion of COVID-19 survivors with at least one sequela symptom decreased from 40.6%at 3 months to 15.8%at 24 months,with anxiety having a higher proportion over a *** and amnesia recovered at the 12-month follow-up,while anxiety,fatigue,and trouble sleeping remained after ***,one(3.1%)case presented two recurrences of PTB and no re-positive COVID-19during the follow-up *** The proportion of long symptoms in COVID-19 with PTB survivors decreased over time,while nearly one in six still experience persistent symptoms with a higher proportion of *** recurrence of PTB and the psychological support of COVID-19 with PTB after discharge require more attention.

关键词： COVID-19 Pulmonary tuberculosis Long-term Sequela Recurrence Re-positive

Application of Dual-blade Stator to Low-speed Ratio Performance Improvement of Torque Converters

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2016年第2期29卷 293-300页

作者： wu Guangqiang WANG Lijun Automotive School Tongji University Institute of Industrial Science the University of Tokyo

With application of the lock-up clutch in the torque converter（TC）, fuel economy is not much determined by its high-speed ratio transmission efficiency. As a benefit, more researches are focused on its low-speed ratio performance so as to improve vehicle gradeability and launching acceleration performance. According to the results of computational fluid dynamics（CFD） analysis, hydrodynamic loss inside the stator cascade accounts for 42% of the total energy loss at stalling speed ratio. It is found that upstream flow with large impingement angle results in boundary layer separation at the leading edge, which aggregates hydrodynamic loss and decreases circular flow rate dramatically at low-speed ratio. In this paper, a dual-blade stator is proposed to suppress the boundary layer separation, which is parameterized by using the non-uniform rational B spline（NURBS） method. The mean camber line and blade profile curve are expressed by a three control points quadratic open NURBS and a cubic closed one respectively. The key design parameters included the slot width and suction side shape of the primary blade are analyzed. The most effective slot width is found to be between 4% and 8% chord length, and the boundary layer separation can be suppressed completely by decreasing distribution of momentum moment at the primary blade and adding it to the leading edge of the secondary blade. As a result, circular flow rate and impeller torque capacity is increased by 17.9% and 9.6% respectively at stalling speed ratio, meanwhile, low-speed ratio efficiency is also improved. Maximum efficiency at high-speed ratio decreases by 0.5%, which can be ignored as the work of lock-up clutch. This research focuses on using the dual-blade stator to optimize low-speed ratio performance of the TC, which is benefit to vehicle power performance.

关键词： torque converter dual-blade stator boundary layer separation non-uniform rational B spline

Nonequilibrium Microstructures and Phase Evolutions of and Iron-based Laser Clad Coating

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 1999年第6期15卷 541-547页

作者： wu, XL Chen, GN Chinese Acad Sci Inst Mech Lab Nonlinear Mech Continuous Media Beijing 100080 Peoples R China

The microstructural and compositional features of the laser-solidified microstructures and phase evolutions occurring during high temperature tempering were investigated by using analytical electron microscopy with energy dispersive X-ray analysis. The cladded alloy, a powder mixture of Fe, Cr, W, Ni and C with a weight ratio of 10:5: 1:1:1, was processed with a 3 kW continuous wave CO2 laser. The cladded coating possessed the hypoeutectic microstructure of the primary dendritic γ-austenite and interdendritic eutectic consisting of (γ+M7C3). The γ-austenite is a nonequilibrium phase with extended solid solution of alloying elements. And, a great deal of fine structures, i.e., a high density ofdislocations,twins,andstackingfaultsexistedinaustenite phase. During high temperature aging,the precipitation of M23C6, MC and M2C in austenite and in situ transformation of M7C3(+γ) → M23C6 and M7C3+7→ M6C occurred. The laserclad coating revealed an evident secondary hardening and superior impact wear resistance

关键词： Cladding (coating)

A comprehensive review of research progress in Chinese medicines for primary liver cancer treatment

在线全文

学校读者我要写书评

暂无评论

Traditional Medicine Research 2022年第2期7卷 1-10页

作者： Kui Liao Le-Yi Gong Yi Yang Yi-Mei He fang-Liang Wang Yuan-Qiong Huang Zhi-Gui wu Department of Pharmacy Affiliated Hospital of Southwest Medical UniversityLuzhou 646000China School of Pharmacy Southwest Medical UniversityLuzhou 646000China Department of Nephropathy Luzhou Traditional Chinese Medicine HospitalLuzhou 646000China.

Primary liver cancer seriously threatens human health,affects the quality of life,and has a high mortality *** Chinese medicine(TCM)has long been used in the prevention,treatment,and adjuvant treatment of primary liver *** trials were conducted in recent years to evaluate the efficacy and safety of *** mechanism of action of TCM in primary liver cancer treatment also received extensive *** study summarizes the common monomial Chinese herbal medicines and their components,formulae,and the proprietary Chinese medicines used to treat primary liver *** medicines include Chansu(Bufonis venenum),Kushen(Sophorae flavescentis radix),Renshen(Ginseng radix et rhizoma),and Jianghuang(Curcumae longae rhizoma).This study also reviewed the literature on liver cancer treatment using *** results confirmed the safety and efficacy of TCM in liver cancer *** possible mechanisms involved are also listed,including influencing the cell cycle,inducing cancer cell apoptosis and autophagy,inhibiting cancer cell angiogenesis and metastasis,regenerating the microenvironment and DNA methylation,and regulating the innate immune *** primary liver cancer patients who often have a long disease course,Chinese herbal medicine often plays a role in protecting and conditioning the *** aimed at finding more traditional Chinese herbal medicines and their mechanisms of action should be *** study aimed to provide a scientific reference for further research and the rational clinical application of TCM for primary liver cancer treatment.

关键词： primary liver cancer traditional Chinese medicine clinical evaluation pharmacological mechanism

Prohibitin(PHB)interacts with AKT in mitochondria to coordinately modulate sperm motility

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2020年第6期22卷 583-589页

作者： Xiao-Hui Li Ran-Ran Chai Guo-wu Chen Ling-Fei Zhang Wen-Jing Tan-Tai Hui-Juan shi Patricia A Martin-DeLeon Wai-Sum O Hong Chen Department of Anatomy Histology and EmbryologyKey Laboratory of Medical Imaging Computing and Computer Assisted Intervention of ShanghaiSchool of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China Shanghai Ji'Ai Genetics and IVF Institute Obstetrics and Gynecology HospitalInstitute of Reproduction and DevelopmentFudan UniversityShanghai 200011China Key Lab of Reproduction Regulation of NPFPC-Shanghai Institute of Planned Parenthood Research Fudan University Reproduction and Development InstitutionShanghai 200032China Department of Biological Sciences University of DelawareNewarkDE 19716-2590USA School of Biomedical Sciences The University of Hong KongHong Kong SARChina

Prohibitin(PHB),an evoluti on arily con served mitochondrial inner membra ne protein,is highly expressed in cells that require strong mitoch on drial ***,we dem on strated that the deleti on of Phb in spermatocytes results in impaired mitochondrial *** addition,PHB expression in the mitochondrial sheath of human sperm has a significantly negative correlation with mitochondrial reactive oxygen species levels,but a positive one with mitochondrial membrane potential and sperm *** results suggest that mitochondrial PHB expression plays a role in sperm ***,the mechanism of PHB-mediated regulation of sperm motility remai ns unk ***,we dem on strate for the first time that PHB interacts with protei n kinase B(AKT)and exists in a complex with phospho-PHB(pT258)and phospho-AKT in the mitochondrial sheath of murine sperm,as determined using colocalization and coimmunoprecipitation *** blocking AKT activity using wortmannin(a phosphatidylinositol 3-kinase[PI3K]inhibitor),murine sperm have significantly(P<0.05)decreased levels of phospho-PHB(pT258)and the total and progressive ***,significantly(P<0.05)lower levels of phospho-PI3K P85 subunit a+γ(pY199 and pY46)and phospho-AKT(pS473;pT308)are found in sperm from infertile asthenospermic and oligoasthenospermic men compared with no rmospermic subjects,which suggest a reduced activity of the PI3K/AKT pathway in these in fertile ***,these sperm from infertile subjects also have a significantly(P<0.05)lower level of phospho-PHB(pT258).Collectively,our findings suggest that the interaction of PHB with AKT in the mitochondrial sheath is critical for sperm motility,where PHB phosphorylation(pT258)level and PI3K/AKT activity are key regulatory factors.

关键词： male in fertility prohibitin(PHB) protein kinase B(AKT) sperm motility

Intuitionistic fuzzy C-means clustering algorithms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2010年第4期21卷 580-590页

作者： Zeshui Xu Junjie wu School of Economics and Management Southeast UniversityNanjing 210096P.R.China Institute of Sciences PLA University of Sciences and TechnologyNanjing 210007P.R.China Department of Information Systems School of Economics and ManagementBeihang UniversityBeijing 100191P.R.China

Intuitionistic fuzzy sets(IFSs) are useful means to describe and deal with vague and uncertain *** intuitionistic fuzzy C-means algorithm to cluster IFSs is *** each stage of the intuitionistic fuzzy C-means method the seeds are modified,and for each IFS a membership degree to each of the clusters is *** the end of the algorithm,all the given IFSs are clustered according to the estimated membership ***,the algorithm is extended for clustering interval-valued intuitionistic fuzzy sets(IVIFSs).Finally,the developed algorithms are illustrated through conducting experiments on both the real-world and simulated data sets.

关键词： intuitionistic fuzzy set(IFS) intuitionistic fuzzy Cmeans algorithm clustering interval-valued intuitionistic fuzzy set(IVIFS).

Omicron adopts a different strategy from Delta and other variants to adapt to host

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第3期7卷 616-618页

作者： Xiaohong Du Haijun Tang Long Gao Zhao wu fang Meng Ruhong Yan shigang Qiao Jianzhong An Chen Wang F.Xiao-Feng Qin Institute of Clinical Medicine Research Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical UniversitySuzhou 215153China Institute of Systems Medicine Chinese Academy of Medical Sciences&Peking Union Medical CollegeSuzhou Institute of Systems MedicineSuzhou 215123China Deportment of Infectious Disease The First Affiliated Hospital of Anhui Medical UniversityHefei 230000China

Dear Editor,With the ongoing of Corona Virus Disease 2019(COVID-19)epidemic,new strains of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)are continuously *** Delta(B.1.617.2)identified in India,Lambda(C.37),Mu(B.1.621),and Omicron(B.1.1.529)were successively found in Peru,Colombia,and Botswana/South Africa,and subsequently defined as variant of interest(VOI)or variant of concern(VOC).

关键词： acute respiratory Delta

THE STRONG LAW OF LARGE NUMBERS FOR PAIRWISE NQD RANDOM VARIABLES

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2011年第2期24卷 347-357页

作者： Qunying wu Yuanying JIANG College of Science Guilin University of Technology Guilin 541004 China.

In this paper, the almost sure convergence for pairwise negatively quadrant dependent random variables is studied. The strong law of large numbers for pairwise negatively quadrant dependent random variables is obtained. Our results generalize and improve those on almost sure convergence theorems previously obtained by Marcinkiewicz （1937）, Jamison （1965）, Matula （1992） and wu （2001） from the independent identically distributed （i.i.d.） case to pairwise NQD sequences.

关键词： Almost sure convergence pairwise negatively quadrant dependent random variables,strong law of large numbers.

Maneuver Target Detection Method with Iterative Endpoint Fitting Assisted

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Maneuver Target Detection Method with Iterative Endpoint Fit...