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Chinese Journal of Cancer 2014年第5期33卷 241-248页

作者： jin-You Wang Yao Zhu Chao-Fu Wang shi-Lin Zhang Bo Dai ding-Wei Ye Department of Oncology Shanghai Medical CollegeFudan University Department of Urology Shanghai Medical CollegeFudan University Department of Pathology Fudan University Cancer Hospital

Although several models have been developed to predict the probability of Gleason sum upgrading between biopsy and radical prostatectomy specimens,most of these models are restricted to prostatespecific antigen screening-detected prostate *** study aimed to build a nomogram for the prediction of Gleason sum upgrading in clinically diagnosed prostate *** study cohort comprised 269 Chinese prostate cancer patients who underwent prostate biopsy with a minimum of 10 cores and were subsequently treated with radical *** all included patients,220(81.8%) were referred with clinical *** prostate-specific antigen level,primary and secondary biopsy Gleason scores,and clinical T category were used in a multivariate logistic regression model to predict the probability of Gleason sum *** developed nomogram was validated *** sum upgrading was observed in 90(33.5%) *** nomogram showed a bootstrap-corrected concordance index of 0.789 and good calibration using 4 readily available *** nomogram also demonstrated satisfactory statistical performance for predicting significant *** validation of the nomogram published by Chun et *** our cohort showed a marked discordance between the observed and predicted probabilities of Gleason sum *** summary,a new nomogram to predict Gleason sum upgrading in clinically diagnosed prostate cancer was developed,and it demonstrated good statistical performance upon internal validation.

关键词：前列腺癌预测概率临床诊断列线图 logistic回归模型患者中国特异性抗原

Ecological footprint and vulnerability of marine capture fisheries in China

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Acta Oceanologica Sinica 2020年第4期39卷 100-109页

作者： Qi ding Xiujuan Shan Xianshi jin Key Laboratory of Sustainable Development of Marine Fisheries Ministry of Agriculture and Rural Affairs/Shandong Provincial Key Laboratory of Fishery Resources and Ecological EnvironmentYellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdao 266071China Function Laboratory for Marine Fisheries Science and Food Production Processes Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China

China(herein referred as China’s mainland,and excluding Hong Kong,Macao and Taiwan)ranks as the world’s leading fishing nation,with approximately 11.1 million tons of domestic marine catch acquired in *** fisheries resources in China are mainly exploited by its 11 coastal provinces and municipalities,and the development of fishing industry varies among ***,few studies have examined the exploitation history of the 11 coastal provinces and *** this paper,we systematically quantified the exploitation history of marine fishery resources in China and then measured the vulnerability of the 11 coastal provinces and municipalities of China to a reduction in marine *** analysis suggested that Chinese marine fisheries experienced rapid growth from the mid-1980 s to the end of the 20 th century,and this rapid increase in marine catches were mainly promoted by increased fishing *** total primary production required level amounted to approximately 80%of the average primary productivity in 2017,and Zhejiang,Fujian,Shandong,Hainan and Guangdong provinces were the main fishing provinces in *** assessing three dimensions of vulnerability(exposure,sensitivity and adaptive capacity)to the impacts of a reduction in marine catches in the 11 coastal provinces and municipalities,we found that Hainan,Guangxi,Zhejiang and Fujian provinces had high or very high vulnerability,while the municipalities of Shanghai and Tianjin had low *** suitable adaptation policies and management plans based on the differences in vulnerability among coastal provinces is important in sustainable fisheries management.

关键词： marine capture fisheries coastal provinces and municipalities exploitation history vulnerability

Magnetically labeled mesenchymal stem cells after autologous transplantation into acutely injured liver

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World Journal of Gastroenterology 2010年第29期16卷 3674-3679页

作者： Xiao-Lei shi jin-Yang Gu Bing Han Hai-Yun Xu Liang Fang Yi-Tao ding Jiangsu Province s Key Medical Center for Hepatobiliary Disease Nanjing 210008 Jiangsu Province China Department of Hepatobiliary Surgery the Af��liated DrumTower Hospital of Nanjing UniversityMedical SchoolNanjing 210008Jiangsu ProvinceChinaJin-Yang GuHai-Yun XuDepartment of Hepatobiliary SurgeryDrumTower Clinical Medical College of Nanjing MedicalUniversityNanjing210008JiangsuProvinceChina

AIM:To evaluate tracking of magnetically labeled mesenchymal stem cells(MSCs) after intraportal ***:Mononuclear cells were isolated from bone marrow aspirates of pigs by density gradient centrifugation,cultured and expanded,after which,they were incubated with super paramagnetic iron oxide(SPIO).Prussian blue staining was performed to highlight intracellular *** establish swine models of acute liver injury,0.5 g/kg D-galactosamine was administrated to 10 pigs,six of which were injected via their portal veins with SPIO-labeled MSCs,while the remaining four were injected with unlabeled *** resonance imaging(MRI) was performed with a clinical 1.5T MR scanner immediately before transplantation and 6 h,3 d,7 d and 14 d after *** blue staining was again performed with the tissue slices at the ***:Prussian blue staining of SPIO-labeled MSCs had a labeling efficiency of almost 100%.Signal intensity loss in the liver by SPIO labeling on the FFE(T2*WI) sequence persisted until 14 d after *** analysis by Prussian blue staining confirmed homing of labeled MSCs in the liver after 14 d;primarily distributed in hepatic sinusoids and liver ***:MSCs were successfully labeled with SPIO in *** can monitor magnetically labeled MSCs transplanted into the liver.

关键词： Magnetic resonance imaging Mesenchymal stem cells Super paramagnetic iron oxide Stem cell transplantation

AN ASYMPTOTIC PRESERVING SCHEME FOR THE VLASOV-POISSON-FOKKER-PLANCK SYSTEM IN THE HIGH FIELD REGIME

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Acta Mathematica Scientia 2011年第6期31卷 2219-2232页

作者： shi jin Li Wang Department of Mathematics and Institute of Natural Sciences Shanghai Jiao Tong University Shanghai 20040 China Department of Mathematics University of Wisconsin-Madison 480 Lincoln Drive Madison WI 53706 USA

The Vlasov-Poisson-Fokker-Planck system under the high field scaling describes the Brownian motion of a large system of particles in a surrounding bath where both collision and field effects （electrical or gravitational） are dominant. Numerically solving this system becomes challenging due to the stiff collision term and stiff nonlinear transport term with respect to the high field. We present a class of Asymptotic-Preserving scheme which is efficient in the high field regime, namely, large time steps and coarse meshes can be used, yet the high field limit is still captured. The idea is to combine the two stiff terms and treat them implicitly. Thanks to the linearity of the collision term, using the discretization described in [jin S, Yah B. J. Comp. Phys., 2011, 230： 6420-6437] we only need to invert a symmetric matrix. This method can be easily extended to higher dimensions. The method is shown to be positive, stable, mass and asymptotic preserving. Numerical experiments validate its efficiency in both kinetic and high field regimes including mixing regimes.

关键词： Vlasov-Poisson-Fokker-Planck equation high field limit asymptoticpreserving schemes

ON THE QUASI-RANDOM CHOICE METHOD FOR THE LIOUVILLE EQUATION OF GEOMETRICAL OPTICS WITH DISCONTINUOUS WAVE SPEED

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Journal of Computational Mathematics 2013年第6期31卷 573-591页

作者： jingwei Hu shi jin Institute for Computational Engineering and Sciences (ICES) The University of Texas at Austin 201 East 24th St Stop C0200 Austin TX 78712 USA Department of Mathematics University of Wisconsin-Madison 480 Lincoln Drive Madison WI 53706 USA Department of Mathematics Institute of Natural Sciences and MOE Key Lab in Scientific and Engineering Computing Shanghai Jiao Tong University Shanghai 200240 China

We study the quasi-random choice method （QRCM） for the Liouville equation of ge- ometrical optics with discontinuous locM wave speed. This equation arises in the phase space computation of high frequency waves through interfaces, where waves undergo partial transmissions and reflections. The numerical challenges include interface, contact discon- tinuities, and measure-valued solutions. The so-called QRCM is a random choice method based on quasi-random sampling （a deterministic alternative to random sampling）. The method not only is viscosity-free but also provides faster convergence rate. Therefore, it is appealing for the prob!em under study which is indeed a Hamiltonian flow. Our analy- sis and computational results show that the QRCM 1） is almost first-order accurate even with the aforementioned discontinuities; 2） gives sharp resolutions for all discontinuities encountered in the problem; and 3） for measure-valued solutions, does not need the level set decomposition for finite difference/volume methods with numerical viscosities.

关键词： Liouville equation High frequency wave Interface Measure-valued solution,Random choice method Quasi-random sequence.

A Study of Hyperbolicity of Kinetic Stochastic Galerkin System for the Isentropic Euler Equations with Uncertainty

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Chinese Annals of Mathematics,Series B 2019年第5期40卷 765-780页

作者： shi jin Ruiwen SHU School of Mathematical Sciences Institute of Natural SciencesMOE-LSEC and SHL-MACShanghai Jiao Tong University800 Dongchuan Rd.Shanghai 200240China Department of Mathematics University of MarylandCollege Park4176 Campus Dr.College ParkMD 20742USA.

The authors study the fluid dynamic behavior of the stochastic Galerkin(SG for short) approximation to the kinetic Fokker-Planck equation with random *** the SG system at the kinetic level is hyperbolic, its fluid dynamic limit, as the Knudsen number goes to zero and the underlying kinetic equation approaches to the uncertain isentropic Euler equations, is not necessarily hyperbolic, as will be shown in the case study fashion for various orders of the SG approximations.

关键词： Hyperbolic equations Uncertainty quantification Stochastic Galerkin methods

Analysis of energy pile groups subjected to non-uniform thermal loadings

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Underground Space 2023年第2期9卷 91-104页

作者： Kang Fei shi-Jia ding Hong-Yu Qin Department of Civil Engineering Yangzhou UniversityYangzhouJiangsu 225127China College of Science and Engineering Flinders UniversityAdelaide SA5042Australia

Sequentially coupled thermal-stress finite element analyses were performed to investigate the mechanical behaviors of an energy pile group subjected to non-uniform thermal *** group effect was highlighted by comparing the thermo-mechanical responses with those of the single pile *** to the thermal interactions between piles,the group piles’temperatures were higher than that of the isolated single *** only part of the piles served as heat exchangers,i.e.,the pile group was thermal loaded unevenly,there were dif-ferential deformations between the heated and the non-heated *** to the pile-raft-pile interaction,the axial forces of the piles chan-ged *** location of the heated pile had an important influence on the thermally induced axial force,while the effect of the soil’s coefficient of thermal expansion was not *** by the numerical result,a simplified method was proposed to capture the main characteristics of energy pile groups and to facilitate the *** proposed method was developed in the framework of the traditional load transfer approach,and the pile-raft-pile interaction was *** applying different temperature increments to dif-ferent piles,the non-uniform thermal loading was *** proposed method was verified by comparing with the finite element anal-ysis results and the data collected from the literature.

关键词： Energy pile group Non-uniform thermal loading Group effect Thermo-mechanical response

A Review on Lower Limb Rehabilitation Exoskeleton Robots

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Chinese Journal of Mechanical Engineering 2019年第4期32卷 2-12页

作者： Di shi Wuxiang Zhang Wei Zhang Xilun ding School of Mechanical Engineering and AutoMation Beihang University Beijing 100191 China Beijing Advanced Innovation Center for Biomedical Engineering Beihang University Beijing 100191 China.

Lower limb rehabilitation exoskeleton robots integrate sensing, control, and other technologies and exhibit the characteristics of bionics, robotics, information and control science, medicine, and other interdisciplinary areas. In this review, the typical products and prototypes of lower limb exoskeleton rehabilitation robots are introduced and stateof-the-art techniques are analyzed and summarized. Because the goal of rehabilitation training is to recover patients’ sporting ability to the normal level, studying the human gait is the foundation of lower limb exoskeleton rehabilitation robot research. Therefore, this review critically evaluates research progress in human gait analysis and systematically summarizes developments in the mechanical design and control of lower limb rehabilitation exoskeleton robots. From the performance of typical prototypes, it can be deduced that these robots can be connected to human limbs as wearable forms;further, it is possible to control robot movement at each joint to simulate normal gait and drive the patient’s limb to realize robot-assisted rehabilitation training. Therefore human–robot integration is one of the most important research directions, and in this context, rigid-flexible-soft hybrid structure design, customized personalized gait generation, and multimodal information fusion are three key technologies.

关键词： Control method Lower limb exoskeleton Mechanical design Rehabilitation robot

Application of Fourier transform ion cyclotron resonance mass spectrometry in molecular characterization of dissolved organic matter

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Science China Earth Sciences 2022年第12期65卷 2219-2236页

作者： Chen HE ding HE Chunmao CHEN Quan shi State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing 102249China Department of Ocean Science and Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) The Hong Kong University of Science and TechnologyHong Kong 999077China

Dissolved organic matter(DOM)plays an important role in the global carbon cycle,and an in-depth analysis of its chemical composition is fundamental to the study of its environmental and biogeochemical behavior and *** is a complex mixture of organic substances,and determining its molecular composition is a long-standing challenge in the field of analytical *** development and application of Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR MS)has enabled the identification of the chemical composition of DOM at the molecular *** paper summarizes progress made in the molecular characterization of DOM based on the FT-ICR MS technique,including DOM sample pretreatment methods,mass spectrometry ionization techniques,data acquisition,data processing and presentation,and molecular structure *** on the work done by the instrument at the State Key Laboratory of Heavy Oil Processing in the China University of Petroleum,Beijing,we introduce applications of FT-ICR MS in the fields of earth science,environmental science and engineering,and look ahead to further research directions in the future.

关键词： Dissolved organic matter FT-ICR MS Molecular composition Recalcitrant dissolved organic matter High resolution mass spectrometry

THE l^1-STABILITY OF A HAMILTONIAN-PRESERVING SCHEME FOR THE LIOUVILLE EQUATION WITH DISCONTINUOUS POTENTIALS

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Journal of Computational Mathematics 2009年第1期27卷 45-67页

作者： Xin Wen shi jin LSEC ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China Department of Mathematics University of Wisconsin Madison WI 53706 USA

We study the l^1-stability of a Haxniltonian-preserving scheme, developed in [jin and Wen, Comm. Math. Sci., 3 （2005）, 285-315], for the Liouville equation with a discontinuous potential in one space dimension. We prove that, for suitable initial data, the scheme is stable in the l^1-norm under a hyperbolic CFL condition which is in consistent with the l^1-convergence results established in [Wen and jin, SIAM J. Numer. Anal., 46 （2008）, 2688-2714] for the same scheme. The stability constant is shown to be independent of the computational time. We also provide a counter example to show that for other initial data, in particular, the measure-valued initial data, the numerical solution may become l^1-unstable.

关键词： Liouville equations Hamiltonian preserving schemes Discontinuous potentials,l^1-stability Semiclassical limit.