检索结果-南通市图书馆

The Abnormal High Expression of B Cell Activating Factor Belonging to TNF Superfamily (BAFF) and Its Potential Role in Kidney Transplant Recipients

引用

Cellular & Molecular Immunology 2008年第6期5卷 465-470页

作者： Haiyan Xu Xiaozhou He Qing Liu Yingdi Chen Yibei Zhu dan shi Xueguang Zhang The Third Affiliated Hospital of Soochow University Department ofUrology Medicine Changzhou Jiangsu China The First Affiliated Hospital of Soochow University 135 Clinical KeyLaboratory of Jiangsu Province Biotechnology Institute Laboratory SuzhouJiangsu China

B cell activating factor belonging to TNF superfamily （BAFF） is a critical regulator of B cell maturation and survival In this present study, the expression characteristic of BAFF in kidney transplantation recipients was investigated, its potential significance was analyzed and peripheral blood of follow-up kidney transplant recipients was studied. Flow cytometric assay results showed that, cell-surface BAFF was significantly highly expressed on peripheral CD3＋ T lymphocytes in 〉 5 yrs group of kidney transplant recipients, compared with other groups （p 〈 0.05）. BAFF expression could be found on CD4＋ T cells and CD8＋ T cells. The BAFF mRNA levels in peripheral mononuclear cells were consistent with the protein levels. However, serum soluble BAFF levels were inter- individually different in each group. Stratified by renal function, it was found that cell-surface BAFF levels were significantly higher in those with abnormal renal function, compared with recipients with normal renal function （p 〈 0.05）. ELISA assay results showed that expression levels of cell surface BAFF were significantly correlated with anti-HLA I ＆ II antibodies. These results indicate that BAFF may be involved in the development of graft-loss and influences the long-time outcome of kidney allografl, likely mediated by interfering with immune response. Cellular ＆ Molecular Immunology. 2008;5（6）：465-470.

关键词： BAFF expression renal allograft rejection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PC构件在装配式住宅施工中的问题及处理措施

引用

工程建设与设计 2024年第11期 124-126页

作者：龚洁杜彩红石虎旦宋啸马涛中建四局华南建设有限公司广州510665

以深国际万科和风轩项目为例,该项目是采用PC构件的装配式住宅项目,具体型式为内浇外挂。在项目施工过程中,通过现场长期摸索,总结出PC构件在装配式住宅施工中的难点,如塔吊的选型、塔吊和施工电梯附墙、爬架附墙的施工难点,并提出相应... 详细信息

以深国际万科和风轩项目为例,该项目是采用PC构件的装配式住宅项目,具体型式为内浇外挂。在项目施工过程中,通过现场长期摸索,总结出PC构件在装配式住宅施工中的难点,如塔吊的选型、塔吊和施工电梯附墙、爬架附墙的施工难点,并提出相应的处理措施。

关键词：装配式建筑 PC构件难点处理措施

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

2种植物提取物对杂拟谷盗的生物活性及几种酶活性的影响

引用

草地学报 2024年第7期32卷 2062-2071页

作者：石丹妮康鹏常静马崇勇白文宝韩丽王布赫李海平内蒙古农业大学园艺与植物保护学院内蒙古呼和浩特010019 内蒙古自治区林业和草原有害生物防治检疫总站内蒙古呼和浩特010020 呼和浩特市林业和草原保护中心内蒙古呼和浩特010030

杂拟谷盗(Tribolium confusum)是一种重要的储粮害虫,熏蒸是目前主要的防治方法。相比化学熏蒸,植物源杀虫剂作用方式多样且对环境和粮食安全。因此本论文研究了2种植物[瑞香狼毒(Stellera chamaejasme L.)根石油醚提取物和百里香(Thymu... 详细信息

杂拟谷盗(Tribolium confusum)是一种重要的储粮害虫,熏蒸是目前主要的防治方法。相比化学熏蒸,植物源杀虫剂作用方式多样且对环境和粮食安全。因此本论文研究了2种植物[瑞香狼毒(Stellera chamaejasme L.)根石油醚提取物和百里香(Thymus mongolicus Ronn.)甲醇提取物]对杂拟谷盗的熏蒸、拒食和驱避活性,以及对杂拟谷盗2种靶标酶和3种解毒酶活性的影响。结果表明,瑞香狼毒根石油醚提取物和百里香甲醇提取物熏蒸杂拟谷盗24 h后,致死中浓度(Lethal concentration,LC 50)分别为88.50和119.57 mg·L^(-1);拒食处理杂拟谷盗5 d后的拒食中浓度(Antifeedant concentration,AFC 50)分别为23.00和14.78 mg·L^(-1);4 h的驱避率分别为63.49%和71.90%。2种植物提取物对杂拟谷盗乙酰胆碱酯酶和三磷酸腺苷酶活性均有抑制作用。2种植物提取物处理杂拟谷盗后,细胞色素P450和谷胱甘肽-S-转移酶活性被诱导升高,而羧酸酯酶活性降低。本试验结果为未来进一步开发利用这2种植物源农药防治储粮害虫提供了一定的理论基础。

关键词：杂拟谷盗植物提取物毒力靶标酶解毒酶

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

人力资本因素对苏北工业化的影响

引用

连云港职业技术学院学报 2005年第4期18卷 19-21页

作者：史丹连云港职业技术学院江苏连云港222006

工业化是一国或地区从落后走向现代化所必经的阶段。纵观苏南、苏中、苏北经济发展的差距,主要体现在工业化发展程度的不同上,苏北地区工业化水平落后原因是复杂的,其中人力资本因素不可忽略。因此提出加大科教投资力度,提高人力资源素... 详细信息

工业化是一国或地区从落后走向现代化所必经的阶段。纵观苏南、苏中、苏北经济发展的差距,主要体现在工业化发展程度的不同上,苏北地区工业化水平落后原因是复杂的,其中人力资本因素不可忽略。因此提出加大科教投资力度,提高人力资源素质,推进苏北工业化进程。

关键词：苏北人力资本工业化影响

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

New Industrialization in the New Development Stage

引用

China Economic Transition 2021年第4期4卷 74-79页

作者： shi dan Institute of Industrial Economics Chinese Academy of Social Sciences

China needs to promote the coordinated development of new-type industrialization,informatization,urbanization,and agricultural *** its new stage,China’s economy is now on the path of higher quality development that is more efficient,equitable,sustainable,and *** more than 40 years of reform and opening up,China has greatly improved its industrialization,has built an a complete industrial system with huge production capacity,has become the world’s largest manufacturing country and second largest economy,and has successfully explored industrialization in line with China’s conditions.

关键词： Industrialization economy modernization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Coordinated reduction of CO_(2) emissions and environmental impacts with integrated city-level LEAP and LCA method: A case study of Jinan, China

引用

Advances in Climate Change Research 2021年第6期12卷 848-857页

作者： CHEN Sha LIU Ying-Ying LIN Jin shi Xiao-dan JIANG Ke-Jun ZHAO Guang-Lin Department of Environmental Science Key Laboratory of Beijing on Regional Air Pollution ControlBeijing University of TechnologyBeijing100124China Energy Research Institute Beijing100038China College of Engineer Swansea UniversitySwanseaSA18ENUnited Kingdom

The evaluation of the efficiency and feasibility of energy transition and air pollution control at the city level is one of the key points in addressing environmental problems and achieving the goals of CO_(2) emission reduction and carbon neutrality in China. In this study, an integrated method is developed on the basis of the Low Emissions Analysis Platform (LEAP) and life cycle assessment (LCA). The energy demands and environmental co-benefits in Jinan, one of the low-carbon city pilots in China, are quantitatively evaluated under three policy scenarios: low-carbon (LC) policy scenario, pollution control (PC) policy scenario, and deep-level cut of CO_(2) emissions (DCC) scenario from 2016 to 2050. From 2016 to 2030, the PC policies would be more powerful than the LC policies in terms of energy demand decrease. From 2030 to 2050, the LC policies would be more efficient than all the other policies. Promoting energy-saving buildings in the LC scenario would contribute to the continual decline in energy demands. In the DCC scenario, CO_(2), PM_(2.5), PM_(10), CO, NO_(X) and SO_(2) emissions would decline by more than 71.4% relative to the records in 2016. Global warming potential, human toxicity potential, photochemical ozone creation potential, particulate matter formation potential, and acidification potential would also decrease by 81.8%–88.5%. On the basis of the integrated city-level LEAP and LCA method, this study quantifies the various environmental impacts of urban decarbonization policies and provides science-based references for urban low-carbon transformation.

关键词： Coordinated emission reduction Environmental co-benefits LEAP-LCA Jinan

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cloning,expression pattern,and potential role of MAPKp38 and NF-κBp65 in response to lipopolysaccharide in yellow catfish(Pelteobagrus fulvidraco)

引用

Animal Nutrition 2019年第4期5卷 416-423页

作者： dan shi Ye Zhao Lin Feng Yang Liu Wei-dan Jiang Pei Wu Juan Zhao Jun Jiang Xiao-Qiu Zhou College of Animal Science and Technology Sichuan Agricultural UniversityChengdu611130China Animal Nutrition Institute Sichuan Agricultural UniversityChengdu611130China Fish Nutrition and Safety in Production Sichuan University Key Laboratory Sichuan Agricultural UniversityChengdu611130China

Mitogen-activated protein kinases(MAPK) and nuclear factor kappa B(NF-κB) pathways are considered to be two crucial intracellular signaling cascades in pro-inflammatory *** this study,we reported the coding sequences(CDS) of MAPKp38 and NF-κBp65 from yellow *** also investigated the gene structure,expression patterns and functional role in yellow *** CDS of MAPKp38 is1,086 bp encoding 361 amino acids(AA).The MAPKp38 protein has a long highly conserved serine/threonine protein kinases catalytic *** NF-κBp65 CDS is 1,794 bp,and the gene encodes 597 AA,with a Rel homology domain(RHD) which consists of a RHD-DNA-binding domain and an Ig-like,plexins,transcription factors(IPT) ***,MAPKp38 and NF-κBp65 protein of bony fish and other vertebrates have a single *** real-time PCR analysis revealed the presence of the MAPKp38 and NF-κBp65 transcript in 12 tissues of healthy yellow *** highest expression levels of MAPKp38 and NF-κBp65 were detected in the heart and liver,*** stimulation with an intraperitoneal injection of lipopolysaccharide(LPS),the expression levels of MAPKp38 and NF-κBp65 were up-regulated in the *** results indicated that MAPKp38 and NF-κBp65 play important roles in mediating the response protection against LPS in yellow catfish.

关键词： Mitogen-activated protein kinases Nuclear factor kappa B Lipopolysaccharide Expression pattern Yellow catfish

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Framework System of Natural Resource Statement of Assets and Liabilities:An Idea Based on SEEA2012, SNA2008 and National Statement of Assets and Liabilities

引用

Journal of Resources and Ecology 2015年第6期6卷 433-437页

作者： HU Wenlong shi dan GUO Chaoxian Institute of Industrial Economics CASS

1 Introduction"Natural Resource Statement of Assets and Liabilities"(NRSAL)is a new *** exploration of preparing the NRSAL emerges in the tendency from constructing single"natural resource accounting"to comprehensive"natural resource environmental statement system"(Feng et al.2014;Huang and Zhao2015).National Statement of Assets and Liabilities is a table which is built by referring to the Statement

关键词：自然资源环境资产负债表架体报表报告系统

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unraveling electrolyte solvation architectures for high-performance lithium-ion batteries

引用

Science China(Technological Sciences) 2024年第3期67卷 958-964页

作者： YANG MengHao shi Zhe HE ZhiYuan WANG dan School of Materials Science and Engineering Tongji UniversityShanghai 201804China Department of Nuclear Science and Engineering Massachusetts Institute of Technology CambridgeMassachuseis 02139USA School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China

The design of advanced electrolytes hinges critically on a comprehensive comprehension of lithium-ion migration mechanisms within these electrochemical systems. Fluorination generally improves the stability and reduces the reactivity of organic compounds, making them potentially suitable for use in harsh conditions such as those found in a battery electrolyte. However,the specific properties, such as the solvation power, diffusivity, ion mobility, and so forth, would depend on the exact nature and extent of the fluorination. In this work, we introduce a theoretical framework designed to facilitate the autonomous creation of electrolyte molecular structures and craft methodologies to compute transport coefficients, providing a physical interpretation of fluoride systems. Taking fluorinated-1,2-diethoxyethanes as electrolyte solvents, we present and analyze the relationship between the electronic properties and atomic structures, and further correlate these properties to the transport coefficients, resulting in a good alignment with the experimental diffusion behaviors and Li-solvation structures. The insights derived from this research contribute to the methodological basis for high-throughput evaluation of prospective electrolyte systems, and consequently, propose strategic directions for the improvement of electrochemical cycle characteristics. This comprehensive exploration of the transport mechanisms enhances our understanding, offering avenues for further advancements in the field of lithium-ion battery technology.

关键词： Unraveling electrolyte solvation architectures for high-performance lithium-ion batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A novel method to improve sow reproductive performance:Combination of pre-weaning immunization against inhibin and post-insemination hCG treatment

引用

Journal of Integrative Agriculture 2020年第9期19卷 2286-2293页

作者： GUO Ri-hong HE Pei-yuan MAI Yan-long DAI Zi-cun CHEN Fang shi Zhen-dan Institute of Animal Science Jiangsu Academy of Agricultural SciencesNanjing 210014P.R.China College of Animal Science and Technology Zhongkai University of Agriculture and EngineeringGuangzhou 510620P.R.China Agricultural Development Service Center of Hekou Town Yunfu 527126P.R.China

The feasibility of a novel method to improve sow reproductive performance by combining inhibin immunization and hCG treatment was tested using in vivo and in vitro experiments. In the in vivo experiment, 106 sows were administered an inhibin immunogen on day 7 prior to weaning, and 56 non-treated sows served as the controls. Sows exhibiting oestrous behaviour on day 5 after weaning were artificially inseminated. On day 5 post-insemination, a subset of 50 inhibin-immunized sows received an injection of 1000 IU human chorionic gonadotropin (hCG). Our results showed that pre-weaning immunization against inhibin marginally improved (P=0.068) total litter size and significantly increased (P=0.044) the live litter size. The overall differences in farrowing rates and live litter size tended toward significance (P=0.10) in the three groups, and the differences in total litter size were not significant (P=0.18). In the in vitro experiment, activin and hCG dose-dependently suppressed (P<0.001) and stimulated (P<0.001) progesterone (P4) secretion in cultured pig granulosa cells (GCs), respectively, and the suppression effect of activin was reversed (P<0.001) by hCG. Activin suppressed P4 secretion mainly by downregulating (P<0.001) the expression of StAR, Cyp11a1, and 3β-HSDII, whereas hCG prevented (P<0.001) the suppression effects. These results indicate that the combination of pre-weaning immunization against inhibin and postinsemination hCG treatment provides a novel method for improving sow reproductive performance.

关键词： sow reproductive performance inhibin hCG progesterone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：