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城市社区老年人“医体结合”健康促进服务需求的调查研究

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当代体育科技 2024年第3期14卷 82-85页

作者：刘生明宁夏师范学院宁夏固原756000

伴随着人口老龄化的持续推进,我国在养老方面的形势日益严峻,该文具体结合了医体结合的理念背景,分析城市社区老年人医体结合健康促进服务的需求现状。采用问卷调查法对城市社区老年人的体育健康需求、医疗健康需求进行调查分析。结果发... 详细信息

伴随着人口老龄化的持续推进,我国在养老方面的形势日益严峻,该文具体结合了医体结合的理念背景,分析城市社区老年人医体结合健康促进服务的需求现状。采用问卷调查法对城市社区老年人的体育健康需求、医疗健康需求进行调查分析。结果发现,目前,在城市社区内部,医疗和体育两大模块的配合度不足,同时老年人对其的需求却比较高。基于此,该文进一步就老年人医体结合的健康促进服务,提出相应的建议,希望进一步丰富相关研究,为城市社区老年人健康服务新模式的提出提供一定的参考。

关键词：城市社区“医体结合”健康促进服务调查

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己唑醇及其复配剂对河南省禾谷镰孢菌的抑制活性及对小麦赤霉病的室内防效

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农药学学报 2024年第3期26卷 540-548页

作者：李梦雨高续恒钱乐姜佳刘圣明河南科技大学园艺与植物保护学院河南洛阳471023 河南省绿色植保工程技术研究中心河南洛阳471023

禾谷镰孢菌Fusarium graminearum是河南省小麦赤霉病的优势致病菌。为明确己唑醇对禾谷镰孢菌的抑制活性,测定了己唑醇对禾谷镰孢菌不同发育阶段的毒力,并采用菌丝生长速率法测定了己唑醇对采自河南省6个地区的205株禾谷镰孢菌的抑制活... 详细信息

禾谷镰孢菌Fusarium graminearum是河南省小麦赤霉病的优势致病菌。为明确己唑醇对禾谷镰孢菌的抑制活性,测定了己唑醇对禾谷镰孢菌不同发育阶段的毒力,并采用菌丝生长速率法测定了己唑醇对采自河南省6个地区的205株禾谷镰孢菌的抑制活性,最后采用胚芽鞘接种法测定了己唑醇对小麦赤霉病的室内防效。结果表明:己唑醇对禾谷镰孢菌不同发育阶段的抑制活性存在较大差异,EC_(50)值(μg/mL)从大到小依次为孢子萌发(22.5750)>分生孢子产量(2.1686)>芽管伸长(0.8922)>菌丝生长(0.3862)。己唑醇对205株禾谷镰孢菌的EC_(50)值在0.0345~0.9439μg/mL之间,平均EC_(50)值为(0.3578±0.1928)μg/mL;敏感性频率分布均呈连续单峰曲线,表明田间不存在对己唑醇敏感性下降的抗性亚群体。己唑醇与多菌灵、咯菌腈、氰烯菌酯、咪鲜胺及氟唑菌酰羟胺复配,表现出不同程度的相加或增效作用,增效系数(SR)范围在0.5042~3.7293之间。其中,己唑醇与氟唑菌酰羟胺按质量比1:5复配时,SR最大,为3.7293,实际EC_(50)值为0.0133μg/mL。室内防效测定结果显示,复配剂的防治效果显著高于单一药剂多菌灵、己唑醇和氟唑菌酰羟胺。己唑醇与氟唑菌酰羟胺按质量比1:5复配后在9μg/mL下,对小麦胚芽鞘的防效为93.93%。生产中可将己唑醇与氟唑菌酰羟胺或咯菌腈进行复配或轮换使用,以延缓田间抗药性的产生。该研究结果可为己唑醇的科学使用以及小麦赤霉病的综合防治提供理论依据与数据支持。

关键词：己唑醇杀菌剂复配禾谷镰孢菌抑制活性小麦赤霉病防治效果

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叶菌唑及其复配剂对河南省假禾谷镰孢菌的抑制活性及对小麦茎基腐病的室内防效

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农药学学报 2024年第4期26卷 781-789页

作者：王鑫雨高续恒钱乐姜佳刘圣明河南科技大学园艺与植物保护学院植物保护系河南洛阳471023 河南省绿色植保工程技术研究中心河南洛阳471023

主要由假禾谷镰孢菌Fusarium pseudograminearum引起的小麦茎基腐病是严重影响小麦产量的真菌病害。为明确叶菌唑对河南省小麦茎基腐病菌的抑制活性,测定了叶菌唑对从供试的219株菌株中随机选取的3株菌株(JY2208、HB2201和XC2116)不同... 详细信息

主要由假禾谷镰孢菌Fusarium pseudograminearum引起的小麦茎基腐病是严重影响小麦产量的真菌病害。为明确叶菌唑对河南省小麦茎基腐病菌的抑制活性,测定了叶菌唑对从供试的219株菌株中随机选取的3株菌株(JY2208、HB2201和XC2116)不同发育阶段的毒力,以及叶菌唑分别与咪鲜胺、氰烯菌酯、氟啶胺和咯菌腈按质量比5:1、3:1、1:1、1:3和1:5复配对菌株JY2208的联合毒力;采用胚芽鞘接种法测定了叶菌唑及其复配剂对小麦茎基腐病的室内防效。结果显示:叶菌唑对3株假禾谷镰孢菌JY2208、HB2201和XC2116菌株菌丝生长、分生孢子产生、孢子萌发及芽管伸长的EC50值分别为(0.0397±0.0035)、(0.9549±0.1152)、(0.6114±0.0393)及(0.0235±0.0015)μg/mL;叶菌唑对219株假禾谷镰孢菌菌丝生长的EC50值范围为0.0207~0.0839μg/mL,平均EC50值为(0.0406±0.0114)μg/mL,敏感性频率分布呈连续单峰曲线,可作为河南省假禾谷镰孢菌对叶菌唑的敏感性基线。叶菌唑与咪鲜胺、氰烯菌酯、氟啶胺以及咯菌腈复配的增效系数(SR)范围为0.51~2.32,不同组合、不同配比的复配剂均表现为相加作用或增效作用,表明叶菌唑可以与咪鲜胺、氰烯菌酯、氟啶胺、咯菌腈复配使用。其中,当叶菌唑与氟啶胺按质量比5:1复配时,增效作用最强,SR为2.32。8%叶菌唑悬浮剂与50%氟啶胺悬浮剂按有效成分质量比5:1复配,在80μg/mL剂量下,对小麦茎基腐病的室内防治效果达100%。该研究结果可为小麦茎基腐病的防控提供依据。

关键词：假禾谷镰孢菌小麦茎基腐病叶菌唑复配剂抑菌活性防治效果

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琥珀酸脱氢酶抑制剂类杀菌剂对禾谷丝核菌的抑制活性及结合模式

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农药学学报 2024年第4期26卷 757-764页

作者：周温棋高续恒成泽珺郑伟刘圣明徐建强河南科技大学园艺与植物保护学院植物保护系河南洛阳471023

主要由禾谷丝核菌Rhizoctonia cerealis引起的小麦纹枯病是一种土传真菌病害,自20世纪90年代中期以来,黄淮麦区小麦纹枯病逐渐由次要病害上升为主要病害,对常见的杀菌剂类型已经出现了抗性菌株。新商品化的琥珀酸脱氢酶抑制剂类(SDHIs)... 详细信息

主要由禾谷丝核菌Rhizoctonia cerealis引起的小麦纹枯病是一种土传真菌病害,自20世纪90年代中期以来,黄淮麦区小麦纹枯病逐渐由次要病害上升为主要病害,对常见的杀菌剂类型已经出现了抗性菌株。新商品化的琥珀酸脱氢酶抑制剂类(SDHIs)杀菌剂对禾谷丝核菌的抑制活性尚未见报道。本研究选取3株禾谷丝核菌ZMDBY-9、JZWZ-8和ZMDBY-6,采用菌丝生长速率法测定了10种SDHIs类杀菌剂萎锈灵、氟酰胺、噻呋酰胺、啶酰菌胺、吡唑萘菌胺、氟唑菌酰胺、苯并烯氟菌唑、氟吡菌酰胺、氟吡菌酰羟胺和联苯吡嗪菌胺对禾谷丝核菌的抑制活性;采用同源模建及分子对接,研究了RcSDH bcd构成的蛋白模型与10种SDHIs类杀菌剂的结合模式,进一步分析了结合能与抑菌效果的关联性。菌丝生长速率法测定结果显示:苯并烯氟菌唑和氟唑菌酰胺对禾谷丝核菌的抑制活性较高,平均有效抑制中浓度(EC50)值小于0.1 mg/L;氟吡菌酰胺与氟唑菌酰羟胺的抑制活性较弱,平均EC50值大于1 mg/L;其他6种杀菌剂的平均EC50值为0.1~0.6 mg/L。分子对接结果显示:在10种SDHIs类杀菌剂中,含吡唑-4-酰胺结构的药剂对禾谷丝核菌的抑制活性最好,结合能更低。其中7种杀菌剂分子的抑制活性与结合能之间存在一定的关联性,表现为抑制活性强结合能往往较低。本文研究结果为SDHIs类杀菌剂在小麦纹枯病化学防治中的应用及基于琥珀酸脱氢酶的药剂设计提供了参考。

关键词：琥珀酸脱氢酶抑制剂类杀菌剂禾谷丝核菌抑菌活性同源建模分子对接结合模式

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High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy but not to non-invasive mechanical ventilation in reducing intubation rate in hypoxia and dyspnea due to acute heart failure: a systematic review and meta-analysis

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Chinese Medical Journal 2023年第4期136卷 479-481页

作者： Shuai Yang Yan He shengming liu Yuxin Zhang Department of Emergency Intensive Care Unit Zhuhai People’s Hospital(Zhuhai Hospital Affiliated with Jinan University)ZhuhaiGuangdong 519000China Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong 510630China Department of Gastroenterology Zhuhai People’s Hospital(Zhuhai Hospital Affiliated with Jinan University)ZhuhaiGuangdong 519000China

To the Editor:Acute heart failure(AHF)is a leading cause of *** patients with AHF present with hypoxia and *** of these patients often requires oxygenation via facemask and more intensive respiratory support methods,i... 详细信息

关键词： invasive Acute intubation

Take Every Step Firmly with Sharp Eyes

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Chinese Journal of Chemistry 2024年第10期42卷 1065-1066页

作者： shengming Ma Chinese Journal of Chemistry

Chinese Journal of Chemistry(CJC)is committed to becoming a prominent international journal for chemistry and the related *** are working very hard towards this *** offers a diverse range of manuscript types,including... 详细信息

关键词： journal becoming diverse

Novel approaches to produce Al2O3-TiC/TiCN-Fe composite powders directly from ilmenite

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Progress in Natural Science:Materials International 2013年第5期23卷 501-507页

作者： Aitao Tang shengming liu Fusheng Pan College of Materials Science and Engineering Chongqing University Chongqing Academy of Science&Technology National Engineering Research Center for Magnesium Alloys

Al2O3 –TiC/TiCN–Fe composite powders were successfully prepared directly from ilmenite at 1300–1400℃.The effects of Al/C ratio,sintering atmosphere,and reaction temperature and time on the reaction products were *** showed that the nitrogen atmosphere was bene cial to the reduction of ilmenite and the formation of Al2O3 –TiC/TiCN–Fe composite *** the reaction temperature was between 600 and 1100℃,the intermediate products,TiO2,Ti3O5 and Ti4O7 were found,which changed to TiC or TiCN at higher ***/C ratio was found to affect the reaction process and synthesis *** Al addition was 0.5 mol,the Al2O3 phase did not *** content of carbon in TiCN rose when the reaction temperature was increased.

关键词： Ilmenite Al2O3,TiC,TiCN Composite powder Composite materials

Relationships between Terrain Features and Forecasting Errors of Surface Wind Speeds in a Mesoscale Numerical Weather Prediction Model

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Advances in Atmospheric Sciences 2024年第6期41卷 1161-1170页

作者： Wenbo XUE Hui YU shengming TANG Wei HUANG Chinese Academy of Meteorological Sciences Beijing 100081China University of Chinese Academy of Sciences Beijing 101408China Shanghai Typhoon Institute/CMA Shanghai 200030China Key Laboratory of Numerical Modeling for Tropical Cyclone/CMA Shanghai 200030China

Numerical weather prediction(NWP)models have always presented large forecasting errors of surface wind speeds over regions with complex *** this study,surface wind forecasts from an operational NWP model,the SMS-WARR(Shanghai Meteorological Service-WRF ADAS Rapid Refresh System),are analyzed to quantitatively reveal the relationships between the forecasted surface wind speed errors and terrain features,with the intent of providing clues to better apply the NWP model to complex terrain *** terrain features are described by three parameters:the standard deviation of the model grid-scale orography,terrain height error of the model,and slope *** results show that the forecast bias has a unimodal distribution with a change in the standard deviation of *** minimum ME(the mean value of bias)is 1.2 m s^(-1) when the standard deviation is between 60 and 70 m.A positive correlation exists between bias and terrain height error,with the ME increasing by 10%−30%for every 200 m increase in terrain height *** ME decreases by 65.6%when slope angle increases from(0.5°−1.5°)to larger than 3.5°for uphill winds but increases by 35.4%when the absolute value of slope angle increases from(0.5°−1.5°)to(2.5°−3.5°)for downhill *** sensitivity experiments are carried out with a model output statistical(MOS)calibration model for surface wind speeds and ME(RMSE)has been reduced by 90%(30%)by introducing terrain parameters,demonstrating the value of this study.

关键词： surface wind speed terrain features error analysis MOS calibration model

Effect of cigarette smoke extraction on the expression of found in inflammatory zone 1 in rat lung epithelial L2 cells

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Chinese Medical Journal 2014年第12期127卷 2363-2367页

作者： Lin Chunyan Chen Li Huang Zhihong Wu Yi liu shengming Department of Respiratory Medicine First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong 510632China

Background Found in inflammatory zone 1 （FIZZ1） protein increased in pulmonary epithelial cells and in limited amounts of other lung ***1 increased in murine model of smoke induced chronic obstructive pulmonary ***,the direct role of FIZZ1 produced by pulmonary epithelium stimulated with cigarette smoke extraction has not been *** examined the expression and function of FIZZ1 in rat lung epithelial L2 *** The rat lung epithelial L2 cells （CCL 149） were exposed to cigarette smoke extraction,expression of FIZZ1 mRNA was investigated by *** of FIZZ1 protein were detected by Western blotting and laser confocal *** 149 cells were treated with different concentrations and for different time of recombinant protein *** treatment,the expression levels of interleukin 8 （IL-8） were detected by enzyme-linked immunosorbent assay （ELISA）.Results When CCL 149 cells were exposed to cigarette smoke extraction,FIZZ1 mRNA and protein levels expressed significantly higher than control *** protein FIZZ1 promoted the expression of IL-8 in a dose and time dependent manner in a certain *** Cigarette smoke extraction activates FIZZ1 at mRNA and protein levels in CCL 149 *** protein FIZZ1 induces the expression of IL-8 and may thus participate in the process of chronic obstructive pulmonary disease airway inflammation and airflow ***,immune cells such as macrophages,neutrophils and lymphocytes are unavoidably involved in airway inflammatory and immune responses to cigarette smoke,but it is still unclear whether their involvement in the pathogenesis of chronic obstructive pulmonary disease is based on the specific expression in lung epithelial cells of FIZZ1.

关键词： chronic obstructive pulmonary disesease airway epithelium found in inflammatory zone 1 interleukin 8 cigarette smoke extraction