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一类智能控制的认知框架及其实现

中国电机工程学报 2001年第1期21卷 48-51页

作者：盛万兴中国电力科学研究院北京100085

基于认知科学的观点 ,提出了一类智能控制的认知框架 ,它由智能计算结构和人构成 ,能实现人机结合、智能互补。其中的智能计算结构是一种包含两级处理的紧耦合结构 ,前级通过非线性变换 ,实现对输入信息的扩展与增强 ;后级完成中枢处理... 详细信息

基于认知科学的观点 ,提出了一类智能控制的认知框架 ,它由智能计算结构和人构成 ,能实现人机结合、智能互补。其中的智能计算结构是一种包含两级处理的紧耦合结构 ,前级通过非线性变换 ,实现对输入信息的扩展与增强 ;后级完成中枢处理的动态局域网络 ,能实现信息空间的优化分解 ,降低计算复杂性 ,提高效率和实时性。该文分析了框架的功能及有关环节的实现手段。

关键词：智能控制认知信息处理隶属函数人工智能

The Role of Echocardiography in Hypertrophic Cardiomyopathy

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Cardiovascular Innovations and Applications 2017年第B02期2卷 279-286页

作者： Jing Ping Sun xing sheng Yang Shaochun Wang Division of Cardiology Chinese University of Hong KongSha TinHong Kong Affiliated Hospital of Jining Medical University JiningChina

Hypertrophic cardiomyopathy(HCM)is a common genetic cardiovascular disease and appears in all ethnic *** is diagnosed on the basis of left ventricular *** is a key technique in the diagnosis of HCM,the prognosis of patients with HCM,the management strategy for HCM,and the follow-up of patients with *** review briefly describes and discusses the practical use of established echocardiography techniques and the current and emerging echocardiographic methods that can help physicians in the correct diagnostic and pathophysiological assessment of patients with HCM.

关键词： Hypertrophic cardiomyopathy Hypertension Echocardiography

基于小波分析旋转机械转子振动信号的相位测量

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华东理工大学学报（自然科学版） 2008年第6期34卷 887-891页

作者：华容顾幸生上海应用技术学院机械与自动化工程学院上海200235 华东理工大学自动化研究所上海200237

旋转机械的转子振动信号相位测量系统的硬件电路存在着较大的测量误差。其主要原因是电路结构较复杂,易受外界噪声干扰。基于小波分析方法,本文提出一种硬件电路与软件计算相结合提高测量精度的方法。利用偶对称性小波对采集到的转子振... 详细信息

旋转机械的转子振动信号相位测量系统的硬件电路存在着较大的测量误差。其主要原因是电路结构较复杂,易受外界噪声干扰。基于小波分析方法,本文提出一种硬件电路与软件计算相结合提高测量精度的方法。利用偶对称性小波对采集到的转子振动信号变换处理,可以有效地去除A/D转换中叠加的采集噪声以及谐波噪声。并利用二阶牛顿插值公式求取峰值点的位置,对其进行相位测量。仿真计算表明:该方法能有效降低测量误差,提高相位测量的精确度。

关键词：小波分析振动信号去噪相位测量

Clinical Syndromes Associated with Cardiovascular Diseases:A Review

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Cardiovascular Innovations and Applications 2017年第B02期2卷 289-295页

作者： xing sheng Yang Jing Ping Sun Bryan Yan Division of Cardiology Department of Medicine&TherapeuticsPrince of Wales HospitalThe Chinese University of Hong KongShatinN.T.Hong KongChina

In clinical practice,a variety of syndromes are associated with cardiovascular disease and have characteristic *** of them are an autosomal dominant genetic disorder and have different types of cardiovascular abnormalities,including electrocardiographic conduction defects,arrhythmias,cardiomyopathy,vascular and valvular diseases,cardiac septal defects,and pulmonary *** is a growing need for physicians to pay more attention to these syndromes.

关键词： Clinical syndrome Marfan syndrome Down syndrome Ehlers-Danlos syndrome Fabry disease LEOPARD syndrome Loeys-Dietz syndrome Noonan syndrome Turner syndrome

Growth differentiation factor-15 is a prognostic marker in patients with intermediate coronary artery disease

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Journal of Geriatric Cardiology 2020年第4期17卷 210-216页

作者： Wei WANG Xian-Tao SONG Yun-Dai CHEN Fei YUAN Feng XU Min ZHANG Kai TAN xing-sheng YANG Xian-Peng YU Kong-Yong CUI Shu-Zheng LYU Department of Cardiology Beijing Anzhen HospitalCapital Medical University and Beijing Institute of HeartLung and Blood Vessel DiseasesBeijingChina Department of Cardiology the First Medical Center of Chinese PLA General HospitalBeijingChina

Background Growth differentiation factor-15(GDF-15)is involved in multiple processes that are associated with coronary artery disease(CAD).However,little is known about the association between GDF-15 and the future ischemic events in patients with intermediate *** study was conducted to investigate whether plasma GDF-15 constituted risk biomarkers for future cardiovascular events in patients with intermediate *** A prospective study was performed based on 541 patients with intermediate CAD(20%–70%).GDF-15 of each patient was determined in a blinded *** primary endpoint was major adverse cardiac event(MACE),which was defined as a composite of all-cause death,nonfatal myocardial infarction,revascularization and readmission due to angina *** After a median follow-up of 64 months,504 patients(93.2%)completed the ***,the combined endpoint of MACE appeared in 134 patients(26.6%)in the overall population:26 patients died,11 patients suffered a nonfatal myocardial infarction,51 patients underwent revascularization,and 46 patients were readmitted for angina *** plasma levels of GDF-15(median:1172.02 vs.965.25 pg/m L,P=0.014)were higher in patients with ischemic events than those without *** adjusting for traditional risk factors,higher GDF-15 levels were significantly associated with higher incidence of the composite endpoint of MACE(HR=1.244,95%CI:1.048–1.478,Quartile 4 *** 1,P=0.013).Conclusions The higher level of GDF-15 was an independent predictor of long-term adverse cardiovascular events in patients with intermediate CAD.

关键词： Growth differentiation factor-15 Intermediate coronary artery disease Prognosis

Identification of Dysregulated microRNAs in Glioma Using RNA sequencing

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Current Medical Science 2021年第2期41卷 356-367页

作者： Chang LIU Ying-ying GE Xiao-xun XIE Bin LUO Ning SHEN xing-sheng LIAO Shui-qing BI Tao XU Shao-wen XIAO Qing-mei ZHANG Department of Neurosurgery the First Affiliated HospitalGuangxi Medical UniversityNanning 530021China School of Pre-clinical Medicine Guangxi Medical UniversiryNanning 530021China Department of Stomatology the People's Hospital of Guangxi Zhuang Atutonomous RegionNanning 530021China

Glioma is the most common malignant brain tumor in central nervous *** advances in the treatment of glioma such as surgery and chemoradiotherapy,most patients are easy to relapse,resulting in adverse clinical ***,effective molecular=targeting treatment may be one of attractive strategies for glioma *** dysregulated microRNAs(miRNAs),one of the candidates of therapeutic targets,are believed to play an important role in the progression of *** this study,we aimed to examine the expression profile of miRNAs in glioma and provide a reference for glioma ***,expression profile of miRNAs in 5 normal brain tissues,5 low-grade glioma(LGG)tissues and 5 glioblastoma(GBM)tissues was detected by RNA sequencing(RNA-seq).Next,the target genes of differentially expressed miRNAs(DEmiRNAs)were predicted and then GO enrichment and KEGG pathway analysis performed by ***,10 miRNAs which were significantly up-or down-regulated both in GBM and LGG were validated by real-time quantitative PCR(qRT-PCR).RNA-seq results indicated a number of DEmiRNAs in *** were 64 up-regulated miRNAs and 17 down-regulated miRNAs n LGG,and 181 up-regulated miRNAs and 124 down-regulated miRNAs in GBM,*** analysis showed that the target genes of these DEmiRNAs were enriched in various biological processes and signaling pathways such as cell metabolic and developmental *** DEmiRNAs were further confirmed by ***-10b-5p,miRNA-92b-3p and miRNA-455-5p were significantly up-regulated in both GBM and LGG;while miRNA-542-3p was significantly up-regulated in LGG;miRNA-184 and miRNA-206 were significantly down-regulated in both GBM and LGG;miRNA-766-5p and miRNA-1-3p were significantly down-regulated in *** subject of our study demonstrated several dysregulated miRNAs may serve as a potential therapeutic target for gl ioma.

关键词： glioma microRNA RNA-sequencing

多目标协同正弦优化算法求解分布式流水车间调度问题

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控制理论与应用 2024年第6期41卷 1029-1037页

作者：郎峻顾幸生华东理工大学能源化工过程智能制造教育部重点实验室上海200237

针对最小化最大完工时间(makespan)、总拖期以及平均空闲时间的多目标序列相关准备时间分布式流水车间调度问题,本文提出一种多目标协同正弦优化算法(MCSOA).算法主要包括4个核心阶段:在多邻域搜索阶段,提出了基于关键工厂的搜索策略,... 详细信息

针对最小化最大完工时间(makespan)、总拖期以及平均空闲时间的多目标序列相关准备时间分布式流水车间调度问题,本文提出一种多目标协同正弦优化算法(MCSOA).算法主要包括4个核心阶段:在多邻域搜索阶段,提出了基于关键工厂的搜索策略,并通过正弦优化算法控制搜索范围;在破坏重构阶段,设计了一种迭代搜索策略引导个体的进化方向,同时使用正弦优化算法平衡全局开发与局部搜索;在选择阶段,使用非支配排序与参考点的方法筛选优质解,外部档案集用于存储所有非支配解;在协同阶段,设计种群间共享与竞争机制,平衡3个目标的优化.本文通过多目标优化的均匀性、反世代距离和覆盖率3项性能指标验证算法的有效性,并使用非参数检验证明所提出的算法具有显著性优势.

关键词：多目标优化分布式流水车间调度序列相关准备时间正弦优化算法协同优化

数据协调中测量数据方差-协方差估计及过失误差序列补偿算法

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控制理论与应用 2008年第4期25卷 717-722页

作者：吴胜昔赵霞顾幸生华东理工大学自动化系上海200237 上海交通大学自动化系上海200240

数据协调测量误差的方差-协方差矩阵(也称Q矩阵)通常是由操作人员根据仪表的精度事先给定的,由于没有考虑仪表精度的变化,很可能会造成数据的不一致或不准确.基于空间冗余的约束残差,本文提出了一种测量方差-协方差Q矩阵的估计方法,有... 详细信息

数据协调测量误差的方差-协方差矩阵(也称Q矩阵)通常是由操作人员根据仪表的精度事先给定的,由于没有考虑仪表精度的变化,很可能会造成数据的不一致或不准确.基于空间冗余的约束残差,本文提出了一种测量方差-协方差Q矩阵的估计方法,有效地减少了对Q矩阵先验知识的依赖.针对常见非线性或双线性问题,提出了估计方法的应用方案,并给出了侦破过失误差的序列补偿法.最后,某焦化厂的应用示例表明,该方法对于获得Q矩阵的最初估计和侦破过失误差是有效的.

关键词：数据协调方差-协方差 Q矩阵空间冗余过失误差

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空间框架结构非线性分析的简化数值方法

工程力学 2005年第6期22卷 21-27页

作者：吴胜兴康庆河海大学土木工程学院南京210098

钢筋混凝土框架结构正常使用期间是带裂缝工作的,合理的分析方法应考虑因开裂引起的非线性。在杆系结构有限元基础上,根据构件截面广义应力-应变关系,提出了空间框架结构非线性分析的简化数值方法——网格-等效截面法。该方法能考虑材... 详细信息

钢筋混凝土框架结构正常使用期间是带裂缝工作的,合理的分析方法应考虑因开裂引起的非线性。在杆系结构有限元基础上,根据构件截面广义应力-应变关系,提出了空间框架结构非线性分析的简化数值方法——网格-等效截面法。该方法能考虑材料非线性,混凝土开裂导致构件有效刚度降低,混凝土徐变和加载历程等影响因素。给出了相应的实施步骤,并采用通用有限元软件ANSYS部分功能,自编主体计算程序的混合编程方法编制了程序。通过考题,程序编制方法正确,计算精度满足工程要求。最后,采用程序对荷载和温度作用下某超长框架结构进行了计算。

关键词：钢筋混凝土空间框架结构非线性分析网格-等效截面法混合编程