检索结果-南通市图书馆

Characteristics of cytokines in the sciatic nerve stumps and DRG after rat sciatic nerve crush injury

Military Medical Research 2021年第3期8卷 352-362页

作者： Rui-Rui zhang Sai-Ling Chen zhang-Chun Cheng Yin-Ying shen sheng Yi Hui Xu Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education Co-innovation Center of NeuroregenerationNantong UniversityNantong 226001Jiangsu ProvinceChina College of Medicine Nantong UniversityNantong 226001Jiangsu ProvinceChina

Background: Cytokines are essential cellular modulators of various physiological and pathological activities, including peripheral nerve repair and regeneration. However, the molecular changes of these cellular mediators after peripheral nerve injury are still unclear. This study aimed to identify cytokines critical for the regenerative process of injured peripheral ***: The sequencing data of the injured nerve stumps and the dorsal root ganglia(DRG) of Sprague-Dawley(SD) rats subjected to sciatic nerve(SN) crush injury were analyzed to determine the expression patterns of genes coding for cytokines. PCR was used to validate the accuracy of the sequencing ***: A total of 46, 52, and 54 upstream cytokines were differentially expressed in the SN at 1 day, 4 days, and 7 days after nerve injury. A total of 25, 28, and 34 upstream cytokines were differentially expressed in the DRG at these time points. The expression patterns of some essential upstream cytokines are displayed in a heatmap and were validated by PCR. Bioinformatic analysis of these differentially expressed upstream cytokines after nerve injury demonstrated that inflammatory and immune responses were significantly ***: In summary, these findings provide an overview of the dynamic changes in cytokines in the SN and DRG at different time points after nerve crush injury in rats, elucidate the biological processes of differentially expressed cytokines, especially the important roles in inflammatory and immune responses after peripheral nerve injury, and thus might contribute to the identification of potential treatments for peripheral nerve repair and regeneration.

关键词： Peripheral nerve injury Rat sciatic nerve crush injury Sciatic nerve stumps Dorsal root ganglia Upstream cytokines

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical investigations on performance improvement mechanism of a high-power vertical centrifugal pump with special emphasis on hydraulic component matching

引用

Journal of Hydrodynamics 2023年第4期35卷 649-667页

作者： Gang Yang Xi shen De-sheng zhang Wen-hua Luo Jia Meng Xu-tao Zhao Research Center of Fluid Machinery Engineering and Technology Jiangsu UniversityZhenjiang212013China Key Laboratory of Fluid Machinery and Engineering Xihua UniversityChengdu610039China

The purpose of this paper is to investigate the performance improvement mechanism of a high power vertical centrifugal pump by using numerical ***,a comparative study of energy losses and internal flow characteristics in the original and optimized models was carried out with special attention to the hydraulic component *** optimized model(model B)was obtained by optimizing the vaned diffuser and volute based on the original model(model A),mainly the diffuser inlet diameter,diffuser inlet vane angle,volute channel inlet width and volute throat area were ***,the comparative results on performance and energy losses of two models showed that the efficiency and head of model B was significantly increased under design and part-load *** is mainly due to the dramatic reduction of energy loss PL in the diffuser and ***,the comparisons of PL and flow patterns in the vaned diffuser showed that the matching optimization between the model B impeller outlet flow angle and diffuser inlet vane angle resulted in a better flow pattern in both the circumferential and axial directions of the diffuser,which leads to the PL3 *** meridian velocity Vm of model B was significantly increased at diffuser inlet regions and resulted in improvements of flow patterns at diffuser middle and outlet regions as well as pressure expansion ***,the comparisons of PL and flow characteristics in the volute showed that the turbulence loss reduction in the model B volute was due to the flow pattern improvement at diffuser outlet regions which provided better flow conditions at volute inlet *** matching optimization between the diffuser and volute significantly reduced the turbulence loss in volute sections 1–4 and enhanced the pressure expansion capacity in sections 8–10.

关键词： High-power vertical centrifugal pump performance improvement mechanism hydraulic component matching flow pattern energy balance equation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Controlled Fabrication of Cd-Bi Nanoparticles via Sonochemical Method

引用

Chemical Research in Chinese Universities 2005年第6期21卷 646-649页

作者： CHEN Hong-jie LI sheng LI Zhi-wei WU Zhi-shen zhang Ping-yu zhang Zhi-jun Key Laboratory for Special Functional Materials College of Medical Henan Univerity Kaifeng 475001 P. R. China

A sonochemical method for the direct controlled synthesis of Cd-Bi nanoparticles from a bulk Cd-Bi alloy is introduced. The nanoparticles were found to be monodispersed and the size distribution can be easily controlled by adjusting the ultrasonic power. The formation and the constituent of the as-prepared Cd-Bi nanoparticles were revealed by means of X-ray diffraction, differential thermal analysis and thermogravimetry, transmission electron microscopy, and electron diffraction. It was found that the Cd-Bi eutectic alloy nanoparticles are made of the hexagonal phase of metal cadmium and the rhombohedral phase of metal bismuth. In addition, we also found through tribological tests that the powder has an excellent antiwear property.

关键词： Sonochemistry Nanoalloy Controlling fabrication Tribology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kinematics Analysis and Singularity Avoidance of a Parallel Mechanism with Kinematic Redundancy

引用

Chinese Journal of Mechanical Engineering 2022年第5期35卷 244-261页

作者： Chaoyu shen Haibo Qu sheng Guo Xiao Li Robotics Research Center School of MechanicalElectronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China China Waterborne Transport Research Institute Beijing 100088China Key Laboratory of Vehicle Advanced Manufacturing Measuring and Control TechnologyMinistry of EducationBeijing Jiaotong UniversityBeijing 100044China

The kinematic redundancy is considered as a way to improve the performance of the parallel *** this paper,the kinematics performance of a three degree-of-freedom parallel mechanism with kinematic redundancy(3-DOF PM-KR)and the influence of redundant parts on the PM-KR are ***,the kinematics model of the PM-KR is *** inverse solutions,the Jacobian matrix,and the workspace of the PM-KR are ***,the influence of redundancy on the PM-KR is *** there exists kinematic redundancy,the PM-KR possesses fault-tolerant *** locking one actuating joint or two actuating joints simultaneously,the fault-tolerant workspace is *** the position of the redundant part is changed,the workspace and singularity will be *** results show that kinematic redundancy can be used to avoid ***,the simulations are performed to prove the theoretical analysis.

关键词： Parallel mechanism Kinematic redundancy Singularity Simulation analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Super-resolution diffractive neural network for alloptical direction of arrival estimation beyond diffraction limits

引用

Light(Science & Applications) 2024年第8期13卷 1602-1614页

作者： sheng Gao Hang Chen Yichen Wang Zhengyang Duan Haiou zhang Zhi Sun Yuan shen Xing Lin Department of Electronic Engineering Tsinghua UniversityBeijing 100084China Beijing National Research Center for Information Science and Technology Tsinghua UniversityBeijing 100084China

Wireless sensing of the wave propagation direction from radio sources lays the foundation for communication,radar,navigation,***,the existing signal processing paradigm for the direction of arrival estimation requires the radio frequency electronic circuit to demodulate and sample the multichannel baseband signals followed by a complicated computing process,which places the fundamental limit on its sensing speed and energy ***,we propose the super-resolution diffractive neural networks(S-DNN)to process electromagnetic(EM)waves directly for the DOA estimation at the speed of *** multilayer meta-structures of S-DNN generate super-oscillatory angular responses in local angular regions that can perform the all-optical DOA estimation with angular resolutions beyond the diffraction *** spatial-temporal multiplexing of passive and reconfigurable S-DNNs is utilized to achieve high-resolution DOA estimation over a wide field of *** S-DNN is validated for the DOA estimation of multiple radio sources over 5 GHz frequency bandwidth with estimation latency over two to four orders of magnitude lower than the state-of-the-art commercial devices in *** results achieve the angular resolution over an order of magnitude,experimentally demonstrated with four times,higher than diffraction-limited *** also apply S-DNN’s edge computing capability,assisted by reconfigurable intelligent surfaces,for extremely low-latency integrated sensing and communication with low power *** work is a significant step towards utilizing photonic computing processors to facilitate various wireless sensing and communication tasks with advantages in both computing paradigms and performance over electronic computing.

关键词： beyond optical network

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transient Stability Analysis and Design of VSGs with Different DC-Link Voltage Controllers

引用

CSEE Journal of Power and Energy Systems 2024年第2期10卷 593-604页

作者： Chao shen Wei Gu Wanxing sheng Keyan Liu School of Electrical Engineering Southeast UniversityNanjingChina Power Distribution Research Department China Electric Power Research InstituteBeijing 100192China

Virtual synchronous control has been widely studied for the advantages of emulating inertia for voltage source converters (VSCs). A constant dc-link voltage is usually assumed in existing literature to estimate transient stability of virtual synchronous generators (VSGs). However, actual power supply in the dc-side of VSGs is limited and different dc-link voltage controllers are needed to achieve power balance between DC side and AC side. Addition of dc-link voltage controller has great influence on transient behavior of VSGs, which has not been investigated by previous research. To fill this gap, this paper gives insights into the effect of dc-link voltage dynamics on transient stability of VSGs. First, two typical kinds of VSGs with dc-link voltage controllers are introduced. Then, mathematical models considering dc-link dynamics are established and the effect of dc-link voltage controllers on transient synchronization stability of VSGs is revealed through equal area criterion (EAC). It is found that dc-link voltage controller would reduce stability margin of VSGs and design-oriented transient stability analysis is carried out quantitively using critical clearing time (CCT). Finally, simulation results are given to validate correctness of theoretical analysis.

关键词： DC-link voltage dynamics equal area criterion(eac) transient synchronization stability virtual synchronous generator(VSG)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insight into the experiment and extraction mechanism for separating carbazole from anthracene oil with quaternary ammonium-based deep eutectic solvents

引用

Chinese Journal of Chemical Engineering 2024年第1期65卷 188-199页

作者： Xudong zhang Yanhua Liu Jun shen Yugao Wang Gang Liu Yanxia Niu Qingtao sheng College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China

Carbazole is an irreplaceable basic organic chemical raw material and intermediate in *** separation of carbazole from anthracene oil by environmental benign solvents is important but still a challenge in chemical *** eutectic solvents (DESs) as a sustainable green separation solvent have been proposed for the separation of carbazole from model anthracene *** this research,three quaternary ammonium-based DESs were prepared using ethylene glycol (EG) as hydrogen bond donor and tetrabutylammonium chloride (TBAC),tetrabutylammonium bromide or choline chloride as hydrogen bond *** explore their extraction performance of carbazole,the conductor-like screening model for real solvents (COSMO-RS) model was used to predict the activity coefficient at infinite dilution (γ^(∞)) of carbazole in DESs,and the result indicated TBAC:EG (1:2) had the stronger extraction ability for carbazole due to the higher capacity at infinite dilution (C^(∞)) ***,the separation performance of these three DESs was evaluated by experiments,and the experimental results were in good agreement with the COSMO-RS prediction *** TBAC:EG (1:2) was determined as the most promising ***,the extraction conditions of TBAC:EG (1:2) were optimized,and the extraction efficiency,distribution coefficient and selectivity of carbazole could reach up to 85.74%,30.18 and 66.10%,***,the TBAC:EG (1:2) could be recycled by using environmentally friendly water as *** addition,the separation performance of TBAC:EG (1:2) was also evaluated by real crude anthracene,the carbazole was obtained with purity and yield of 85.32%,60.27%,***,the extraction mechanism was elucidated byσ-profiles and interaction energy *** calculation results showed that the main driving force for the extraction process was the hydrogen bonding ((N–H...Cl) and van der Waals interactions (C–H...O and C–H...π),which correspondin

关键词： Carbazole Model anthracene oil Deep eutectic solvents COSMO-RS Extraction mechanism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Robust temporal changes of cellular senescence and proliferation after sciatic nerve injury

引用

Neural Regeneration Research 2022年第7期17卷 1588-1595页

作者： Yin-Ying shen Rui-Rui zhang Qian-Yan Liu Shi-Ying Li sheng Yi Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education Co-innovation Center of NeuroregenerationNMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsNantong UniversityNantongJiangsu ProvinceChina

Cellular senescence and proliferation are essential for wound healing and tissue ***,senescence-proliferation cell fate after peripheral nerve injury has not been clearly ***,post-injury gene expression patterns in rat sciatic nerve stumps(SRP113121)and L4–5 dorsal root ganglia(SRP200823)obtained from the National Center for Biotechnology Information were analyzed to decipher cellular senescence and proliferation-associated genetic *** first constructed a rat sciatic nerve crush ***,β-galactosidase activities were determined to indicate the existence of cellular senescence in the injured sciatic ***67 and EdU immunostaining was performed to indicate cellular proliferation in the injured sciatic *** cellular senescence and proliferation were less vigorous in the dorsal root ganglia than in sciatic nerve *** results reveal the dynamic changes of injury-induced cellular senescence and proliferation from both genetic and morphological aspects,and thus extend our understanding of the biological processes following peripheral nerve *** study was approved by the Animal Ethics Committee of Nantong University,China(approval No.20190226-001)on February 26,2019.

关键词： bioinformatic analysis cellular senescence dorsal root ganglia p16 peripheral nerve regeneration peripheral nerve trauma proliferation rat sciatic nerves sciatic nerve crush β-galactosidase activities

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A survey on online learning and optimization for spark advance control of SI engines

引用

Science China(Information Sciences) 2018年第7期61卷 6-26页

作者： Yahui zhang Xun shen Tielong shen Department of Engineering and Applied Sciences Sophia University

One of the most important factors affecting fuel efficiency and emissions of automotive engines is combustion quality that is usually controlled by managing spark advance(SA) in spark ignition(SI) *** increasing sensing capabilities and enhancements in on-board computation capability, online learning and optimization techniques have been the subject of significant research interest. This article surveys the literature of learning and optimization algorithms with applications to combustion quality optimization and control of SI engines. In particular, this paper reviews extremum seeking control algorithms for iterative solution of online optimization problems, stochastic threshold control algorithms for iterative solution of probability control of stochastic knock event, as well as feedforward learning algorithms for iterative solution of operating-point-dependent feedforward adaptation problems. Finally, two experimental case studies including knock probabilistic constrained optimal combustion control and on-board map learning-based combustion control are carried out on an SI gasoline engine.

关键词： online learning stochastic optimization iterative solution combustion control spark ignition engine

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

基于卡尔加里-剑桥指南的沙龙培训模式提升全科规培医师医患沟通技能的对照研究

引用

中国全科医学 2025年第1期28卷 71-76页

作者：彭涛邹川曾欣张焱沈静四川省成都市第五人民医院全科医学科 611130

背景医患沟通技能是全科医生的核心岗位胜任力之一,高水平的医患沟通能力是创建和谐医患关系的基石,有助于提高患者就医获得感和满意度。而我国全科医生沟通能力普遍偏低,有待探索出一种适应我国国情、满足我国全科医生沟通需求的医患... 详细信息

背景医患沟通技能是全科医生的核心岗位胜任力之一,高水平的医患沟通能力是创建和谐医患关系的基石,有助于提高患者就医获得感和满意度。而我国全科医生沟通能力普遍偏低,有待探索出一种适应我国国情、满足我国全科医生沟通需求的医患沟通培训模式来提高其医患沟通能力。目的探索基于卡尔加里-剑桥指南的沙龙培训模式在全科规培医师医患沟通技能培训中的应用效果,为构建适合我国国情的医患沟通培训体系提供参考依据。方法选取成都市第五人民医院2019—2020年度全科规培医师40名作为研究对象,按照随机数字表法分为沙龙组和对照组,每组20名,其中沙龙组使用基于卡尔加里-剑桥指南的沙龙培训模式进行医患沟通培训,对照组设置为空白对照,培训前、培训后1周分别对两组学员采用标准化病人(SP)模式进行接诊,使用医患沟通评价量表(SEGUE量表)进行现场观察评分,比较两组学员的医患沟通培训效果。结果最终纳入28名,其中沙龙组15名,对照组13名,培训后沙龙组规培医师SEGUE量表评分从(11.80±4.36)分提高至(18.07±4.11)分,对照组规培医师SEGUE量表评分从(12.15±4.63)分提高至(14.46±3.71)分。沙龙组培训后的SEGUE量表评分与培训前的比较,差异有统计学意义(t=3.250,P<0.001);对照组培训后的SEGUE量表评分与培训前比较,差异无统计学意义(t=2.582,P=0.624);培训后对SEGUE量表中的25个项目进行分析,沙龙组与对照组SEGUE量表评分比较,差异有统计学意义(P<0.05)。沙龙组以下5个项目结果优于对照组,准备阶段中的“建立个人信任关系”(93.3%比7.7%)、“保护患者的隐私/尊重患者选择权”(53.3%比15.4%);理解患者阶段中的“认同患者为疾病所付出的努力、改变及其遇到的困难”(33.3%比23.1%)、“表达关心,使患者感到温暖/树立信心”(100.0%比69.2%);结束问诊阶段中的“询问患者是否还有其他的问题需要探讨”(66.7%比23.1%)。结论基于卡尔加里-剑桥指南的沙龙培训模式对全科规培医师进行医患沟通技能培训可增强学员主动参加培训的兴趣和积极性,对于医患沟通能力的提升具有较好的培训效果,值得借鉴和推广。

关键词：全科医学全科医师规范化培训医患沟通沟通培训卡尔加里-剑桥指南

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：