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Classification research of TCM pulse conditions based on multi-label voice analysis

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Journal of Traditional Chinese Medical Sciences 2024年第2期11卷 172-179页

作者： haoran shen Junjie Cao Lin Zhang Jing Li Jianghong Liu Zhiyuan Chu Shifeng Wang Yanjiang Qiao Key Laboratory of TCM-information Engineer of State Administration of TCM School of Chinese Materia MedicaBeijing University of Chinese MedicineBeijing102488China School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Sinosense Technology Co. LtdBeijing100141China

Objective To explore the feasibility of remotely obtaining complex information on traditional Chinese medicine(TCM)pulse conditions through voice *** We used multi-label pulse conditions as the entry point and modeled and analyzed TCM pulse diagnosis by combining voice analysis and machine *** features were extracted from voice recordings in the TCM pulse condition *** obtained features were combined with information from tongue and facial diagnoses.A multi-label pulse condition voice classification DNN model was built using 10-fold cross-validation,and the modeling methods were validated using publicly available *** The analysis showed that the proposed method achieved an accuracy of 92.59%on the public *** accuracies of the three single-label pulse manifestation models in the test set were 94.27%,96.35%,and 95.39%.The absolute accuracy of the multi-label model was 92.74%.Conclusion Voice data analysis may serve as a remote adjunct to the TCM diagnostic method for pulse condition assessment.

关键词： Pulse conditions TCM pulse diagnosis Voice analysis Multi-label classification Machine learning

进一步全面深化改革“六个坚持”原则的三维论析

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中共郑州市委党校学报 2024年第5期 18-23页

作者：申浩然李燕黑龙江省社会科学院经济研究所黑龙江哈尔滨150028 黑龙江省社会科学院马克思主义研究所黑龙江哈尔滨150028

党的二十届三中全会提出的进一步全面深化改革的“六个坚持”原则,是习近平新时代中国特色社会主义思想的世界观和方法论在进一步全面深化改革中的集中体现。从生成逻辑来看,“六个坚持”原则以马克思主义唯物史观和唯物辩证法为理论指... 详细信息

党的二十届三中全会提出的进一步全面深化改革的“六个坚持”原则,是习近平新时代中国特色社会主义思想的世界观和方法论在进一步全面深化改革中的集中体现。从生成逻辑来看,“六个坚持”原则以马克思主义唯物史观和唯物辩证法为理论指导,是对党领导全面深化改革历史经验的传承发扬、对新形势下进一步全面深化改革的现实考量。从核心要义来看,“六个坚持”原则内涵丰富,包括坚持党的全面领导、坚持以人民为中心、坚持守正创新、坚持以制度建设为主线、坚持全面依法治国、坚持系统观念。从价值意蕴来看,“六个坚持”原则深化了对中国特色社会主义改革的规律性认识,提供了进一步全面深化改革的行动指南。

关键词： “六个坚持”原则进一步全面深化改革中国式现代化

商业建筑在地化表达的多维平衡——以杭州湖滨银泰商业区为例

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华中建筑 2024年第6期42卷 77-80页

作者：王健沈浩然浙江大学建筑设计研究院有限公司浙江大学平衡建筑研究中心

作为城市公共活动中使用最频繁的场所之一,商业建筑的在地表达因其自身价值满足给与地域特征表达存在矛盾而体现出内部复杂性。杭州湖滨银泰商业区地处特殊位置环境,承载了深厚的历史文化,面对着复杂的城市要素。通过解读湖滨银泰商业... 详细信息

作为城市公共活动中使用最频繁的场所之一,商业建筑的在地表达因其自身价值满足给与地域特征表达存在矛盾而体现出内部复杂性。杭州湖滨银泰商业区地处特殊位置环境,承载了深厚的历史文化,面对着复杂的城市要素。通过解读湖滨银泰商业区在地表达的内部平衡方式,以期寻求商业建筑在地回应的有效方式。

关键词：商业建筑在地性商业价值湖滨地区

Rolling Decision Model of Thermal Power Retrofit and Generation Expansion Planning Considering Carbon Emissions and Power Balance Risk

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Energy Engineering 2024年第5期121卷 1309-1328页

作者： Dong Pan Xu Gui Jiayin Xu Yuming shen haoran Xu Yinghao Ma Economic and Technology Research Institute State Grid Anhui Electric Power Co.Ltd.Hefei230022China School of Electrical and Automation Engineering Hefei University of TechnologyHefei230009China

With the increasing urgency of the carbon emission reduction task,the generation expansion planning process needs to add carbon emission risk constraints,in addition to considering the level of power ***,methods for quantifying and assessing carbon emissions and operational risks are *** results in excessive carbon emissions and frequent load-shedding on some days,although meeting annual carbon emission reduction ***,in response to the above problems,carbon emission and power balance risk assessment indicators and assessment methods,were proposed to quantify electricity abundance and carbon emission risk level of power planning scenarios,considering power supply regulation and renewable energy fluctuation ***,building on traditional two-tier models for low-carbon power planning,including investment decisions and operational simulations,considering carbon emissions and power balance risks in lower-tier operational simulations,a two-tier rolling model for thermal power retrofit and generation expansion planning was *** model includes an investment tier and operation assessment tier and makes year-by-year decisions on the number of thermal power units to be retrofitted and the type and capacity of units to be ***,the rationality and validity of the model were verified through an example analysis,a small-scale power supply system in a certain region is taken as an *** model can significantly reduce the number of days of carbon emissions risk and ensure that the power balance risk is within the safe limit.

关键词： Carbon emission risk power balance risk thermal power retrofit generation expansion planning

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单细胞测序在心肌梗死中的应用进展

心血管病学进展 2024年第6期45卷 515-518,524页

作者：苏昕宇顾逸淳李芃瑾沈浩然毛路陈艾东江苏大学京江学院江苏镇江212013 南京医科大学江苏省心血管病靶向干预研究国家级重点实验室江苏南京211166 东南大学附属中大医院江苏南京250012 杜伊斯堡-埃森大学神经生物学研究中心德国埃森45127

近年来,心血管疾病中由晚期动脉粥样硬化导致的心肌梗死(MI)成为全球主要的死亡原因之一。在MI中由于其细胞具有高度的异质性,目前在临床阶段一直无有效的靶向治疗策略。揭示单个细胞的基因结构和基因表达状态的单细胞测序技术正在各个... 详细信息

近年来,心血管疾病中由晚期动脉粥样硬化导致的心肌梗死(MI)成为全球主要的死亡原因之一。在MI中由于其细胞具有高度的异质性,目前在临床阶段一直无有效的靶向治疗策略。揭示单个细胞的基因结构和基因表达状态的单细胞测序技术正在各个领域飞速发展,并在MI的临床研究中逐渐被重视。现综述MI单细胞测序方法,并探讨MI细胞异质性、潜在的治疗靶点、心脏重构预后机制,有望为精准和靶向治疗提供依据。

关键词：单细胞测序心肌梗死异质性精准医学

Detachment Behavior of Gecko Toe in Functional Strategies for Bionic Toe

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Journal of Bionic Engineering 2024年第2期21卷 707-717页

作者： Qingfei Han Wei Wang Huan shen Xincheng Feng haoran Zhang Qian Li Yi Sun Huapeng Wu Aihong Ji Lab of Locomotion Bioinspiration and Intelligent Robots College of Mechanical and Electrical EngineeringNanjing University of Aeronautics and AstronauticsNanjing210016China Laboratory of Intelligent Machines School of Energy SystemsLappeenranta-Lahti University of Technology53850LappeenrantaFinland State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjing210016China

Geckos can efficiently navigate complex terrains due to their multi-level adhesive system that is present on their *** setae are responsible for the gecko’s extraordinary adhesion and have garnered wide attention from the scientific *** majority of the reported works in the literature that have dealt with the peeling models mainly focus on the gecko hierarchical adhesive system,with limited attention given to investigating the influence of gecko toe structure on the *** these lines,to gain a deeper understanding of the rapid and effortless detachment abilities of gecko toes,the peeling behavior of gecko toes on vertical surfaces was primarily investigated in this *** specifically,the detachment time of a single toe on a smooth acrylic plate was measured to be 0.41±0.21 ***,it was observed that the toe assumed a"U"-shaped structure upon complete ***,Finite Element Analysis(FEA)models for three different types of gecko toes were developed to simulate both the displacement-peel and the moment-peel *** the segmentation of the adhesive layer led to a gradual decrease in the resultant force,as well as the normal and tangential ***,a gecko-inspired toe model was constructed and powered by Shape Memory Alloy(SMA).A systematic comparison between the vertical drag separation and the outward flip separation was also *** our analysis,it was clearly demonstrated that outward peel separation significantly necessitated the reduction of the peeling force,thus confirming the advantageous nature of the outward motion in gecko toe *** data not only contribute to a deeper understanding of the gecko detachment behavior but also offer valuable insights for the advancement of the wall-climbing robot feet.

关键词： Gecko toes Detachment behavior Finite element analysis Gecko-inspired toe

An Aerial–Wall Robotic Insect That Can Land, Climb, and Take Off from Vertical Surfaces

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Research 2024年第1期2023卷 149-163页

作者： Qian Li Haoze Li Huan shen Yangguang Yu haoran He Xincheng Feng Yi Sun Zhiyuan Mao Guangming Chen Zongjun Tian Lida shen Xiangming Zheng Aihong Ji College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjingChina College of Aerospace Engineering Nanjing University of Aeronautics and AstronauticsNanjingChina State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjingChina

Insects that can perform flapping-wing flight,climb on a wall,and switch smoothly between the 2 locomotion regimes provide us with excellent biomimetic ***,very few biomimetic robots can perform complex locomotion tasks that combine the 2 abilities of climbing and ***,we describe an aerial–wall amphibious robot that is self-contained for flying and climbing,and that can seamlessly move between the air and *** adopts a flapping/rotor hybrid power layout,which realizes not only efficient and controllable flight in the air but also attachment to,and climbing on,the vertical wall through a synergistic combination of the aerodynamic negative pressure adsorption of the rotor power and a climbing mechanism with bionic adhesion *** the basis of the attachment mechanism of insect foot pads,the prepared biomimetic adhesive materials of the robot can be applied to various types of wall surfaces to achieve stable *** longitudinal axis layout design of the rotor dynamics and control strategy realize a unique cross-domain movement during the flying–climbing transition,which has important implications in understanding the takeoff and landing of ***,it enables the robot to cross the air–wall boundary in 0.4 s(landing),and cross the wall–air boundary in 0.7 s(taking off).The aerial–wall amphibious robot expands the working space of traditional flying and climbing robots,which can pave the way for future robots that can perform autonomous visual monitoring,human search and rescue,and tracking tasks in complex air–wall environments.

关键词： robot smoothly Vertical

心脑欣片HPLC指纹图谱建立及7种成分测定

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中医药导报 2024年第3期30卷 50-55页

作者：崔兵高凡田佳业秦飘然丁哲沈浩然党静静刘兴超景忠山国药(唐山)有限公司河北唐山063000 河北中医学院河北石家庄050200 河北省高校中药开发与产业化应用技术研发中心河北石家庄050200 河北省中药组方制剂技术创新中心河北石家庄050200

目的:建立心脑欣片HPLC指纹图谱,并测定红景天苷、酪醇、没食子酸、没食子酸乙酯、对香豆酸、咖啡酸和绿原酸的含量。方法:心脑欣片75%甲醇提取液的分析采用WondaSil C18-WR色谱柱(4.6 mm×250 mm,5μm);流动相为甲醇(A)-0.1%磷酸(B),... 详细信息

目的:建立心脑欣片HPLC指纹图谱,并测定红景天苷、酪醇、没食子酸、没食子酸乙酯、对香豆酸、咖啡酸和绿原酸的含量。方法:心脑欣片75%甲醇提取液的分析采用WondaSil C18-WR色谱柱(4.6 mm×250 mm,5μm);流动相为甲醇(A)-0.1%磷酸(B),梯度洗脱;流速为1.0 mL/min;柱温为35℃;检测波长为275 nm;进样量为20μL。对心脑欣片HPLC指纹图谱进行聚类分析、主成分分析。以没食子酸为内标,采用一测多评法测定多种成分含量。结果:11批样品中HPLC指纹图谱中有24个共有峰,相似度均大于0.960。各批次样品分为3类,4个主成分累积方差贡献率达95.045%,7种成分在各自范围内线性关系良好(r≥0.995),平均加样回收率为96.76%~104.02%,RSD值为0.05%~1.48%。一测多评法结果与外标法接近。结论:该方法简单可靠、重复性好,可用于心脑欣片的质量控制。

关键词：心脑欣片 HPLC指纹图谱化学成分聚类分析主成分分析一测多评法

Microstructure evolution and mechanical properties of the Sip/Zn- Al composite joints by ultrasonic-assisted soldering in air

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China Welding 2018年第2期27卷 39-44页

作者： Kang Yuqing shen haoran Fu Yang Chen Yunru Xu Chang Li Xin Gu Keyun Li Xiaohai An Ledong Wang Qian Guangdong Institute of Special Equipment Inspection and Research Zhanjiang Branch Zhanjiang 524000 China Shanghai Aerospace Equipments Manufacture Shanghai 200245 China School of Materials Science and Engineering Tianjin University of Technology Tianjin 300384 China

Hypereutectic Al -27Si alloys were joined without flux by ultrasonic-assisted soldering at 420 ℃ in air using Zn -5Al the filler alloys, and Si particulate-reinforced Zn - Al based composites filler joints were obtained. The ultrasonic vibration introduced into soldering could influence the migration of Si particles and the microstructure of solidified Zn - Al based alloys. Both the distribution of Si particles and microstructure of the solidified Zn - Al based alloys affected the shear strength of joints. The shear strength increased with the ultrasonic vibration time. The highest average shear strength of joints reached to -68.5 MPa. Transcrystalline rupture mode was observed on the fracture surface.

关键词： Hypereutectic Al - Si alloys ultrasonic soldering microstructure mechanical properties