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Ameliorating effects of Raphanus sativus leaves on sodium arsenite-induced perturbation of blood indices in Swiss albino mice

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Asian Pacific Journal of Tropical Biomedicine 2017年第10期7卷 915-920页

作者： Sayada Dilruba MMHasibuzzaman Mashiur Rahman Nayan Chandra Mohanto sharmin aktar Atiqur Rahman Md Imam Hossain Abu Shadat Mohammod Noman Farjana Nikkon Zahangir Alam Saud Khaled Hossain Department of Biochemistry and Molecular Biology University of RajshahiRajshahi 6205Bangladesh Department of Biochemistry EXIM Bank Agricultural University BangladeshChapainawabganj 6300Bangladesh Department of Biochemistry and Molecular Biology Shahjalal University of Science and TechnologySylhet 3114Bangladesh Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and Technology UniversitySantoshTangail 1902Bangladesh Department of Biotechnology and Genetic Engineering Mawlana Bhashani Science and Technology UniversitySantoshTangail 1902Bangladesh Department of Biochemistry and Molecular Biology University of ChittagongChittagong 4331Bangladesh

Objective: To evaluate the ameliorating effects of Raphanus sativus leaves(RSL)against sodium arsenite(Sa)-induced adverse effects through mice ***: Swiss albino mice were divided into four equal groups: control, Sa, RSL,RSL + Sa. Sa(10 mg/kg body weight/day), and powder form of RSL(50 mg/kg body weight/day) were provided as food supplement orallty. Blood indices were measured using commercially available kits through colorimetric ***: It was observed that lactate dehydrogenase, alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase activities were significantly(P < 0.05)higher in Sa-treated mice than those in the control group. RSL significantly reduced Sainduced elevation of the activities of these enzymes in serum significantly(P < 0.05).Serum butyrylcholinesterase activity and high density lipoproteins cholesterol levels in Satreated mice were significantly(P < 0.05) lower than the control group, and the food supplementation of RSL could significantly(P < 0.05) prevent the reduction of Sa-mediated serum butyryl cholinesterase activity and high density lipoproteins cholesterol levels. RSL could also reduce the Sa-induced elevation of serum urea level significantly(P < 0.05).Conclusions: Results of this study suggest the protective or ameliorating effects of RSL on Sa-induced perturbation of blood indices are related to the hepatic, cardiovascular and kidney dysfunction. Therefore, RSL may be useful to reduce arsenic toxicity in human in the future.

关键词： Sodium arsenite Raphanus sativus leaves Ameliorating effect Serum indices

Determine the Factors of Female Early Age at First Cohabitation: A Case Study of Bangladesh

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Open Journal of Statistics 2015年第6期5卷 494-501页

作者： Md. Yasin Ali Parh sharmin aktar Sumy Md. Sazzad Hossain Department of Statistics Islamic University Kushtia Banglades

The main objective of the current study is to examine the existing situation of female early age at first cohabitation in Bangladesh as well as to identify the factors associated behind this issue. An analysis has been performed by using the secondary data of Bangladesh Demographic and Health Survey (BDHS), 2011. Chi-square test for dependency checking has been performed as bivariate analysis. After performing bivariate analysis, binary logistic regression analysis has been performed. To identify the significant variable, stepwise regression method has also been performed. The result of the study has revealed that women education, household economic status, area of residence, religion and geographical location have significant contribution for adolescent cohabitation. From this study it can be concluded that females who has low education and low socio-economic status are more likely to enter into cohabitation at early adulthood.

关键词： Female Early Age at First Cohabitation Bivariate Analysis Logistic Regression Analysis Odds Ratio Step Wise Regression

In vivo analysis of toxic effect of hydrose used in food preparations in Bangladesh

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Asian Pacific Journal of Tropical Biomedicine 2014年第11期4卷 884-889页

作者： Tuhin Reza sharmin aktar Hasan Al Amin Mashiur Rahman Afroza Arefin Nayan Chandra Mohanto Shahnur Alam Abdullah Al Mamun Anwar Habib Asafudullah Farjana Nikkon Khaled Hossain Zahangir Alam Saud Department of Biochemistry and Molecular Biology.University of Rajshahi Department of Pharmacology Rajshahi Medical College Department of Pathology Rajshahi Medical College

Objective:To evaluate the toxic effect of hydrose used in the molasses preparation in ***:Molasses were collected from open markets in different parts of *** presence of hydrose in selected molasses was detected using commercial *** evaluate the toxic effect of *** albino male mice were divided into four *** Ⅰ was used as control,while Groups Ⅱ,Ⅲ and Ⅳ received hydrose mixing food(5.10 and 25 g/kg food),respectively,and these supplementations were continued to the end of the study(16weeks).Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were *** determine the effect of hydrose on host,blood indices related to liver,heart and kidney dysfunctions were ***:Creatinine and urea levels were significantly(P<0.05) increased in a dose dependent manner in hydrose treated mice,whereas calcium level was significantly decreased in hydrose exposed mice compared to control *** study of kidney showed the glomeruler inflammation,increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control ***:The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment.

关键词： Hydrose Molasses Serum indices

ANTIVIRAL EFFECTS OF BACTERIOCIN AGAINST ANIMAL-TO-HUMAN TRANSMITTABLE MUTATED SARS-COV-2:A SYSTEMATIC REVIEW

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Frontiers of Agricultural Science and Engineering 2021年第4期8卷 603-622页

作者： Dipta DEY Tanzila Ismail EMA Partha BISWAS sharmin aktar Shoeba ISLAM Urmi Rahman RINIK Mahmudul FIROZ Shahlaa Zernaz AHMED Salauddin AL AZAD Ahsab RAHMAN Sadia AFRIN Rezwan Ahmed MAHEDI MdNasir Uddin BADAL Department of Biochemistry and Molecular Biology Bangabandhu Sheikh Mujibur Rahman Science&Technology UniversityGopalganj 8100Bangladesh Department of Microbiology and Biochemistry North South UniversityDhaka 1229Bangladesh Department of Genetic Engineering and Biotechnology Jashore University of Science and TechnologyJashore 7408Bangladesh Department of Microbiology University of DhakaDhaka 1000Bangladesh Department of Naval Architecture and Marine Engineering Bangladesh University of Engineering and TechnologyDhaka 1205Bangladesh Biotechnology and Genetic Engineering Discipline Khulna UniversityKhulna 9208Bangladesh Department of Mechanical and Production Engineering Islamic University of TechnologyGazipur 1704Bangladesh School of Biotechnology Jiangnan UniversityWuxi 214122China Department of Mathematics and Natural Sciences Brae UniversityDhaka 1212Bangladesh Department of Pharmacy Comilla UniversityComilla 3506Bangladesh Department of Biomedical Technology Tampere UniversityTampere 33100Finland

The COVID-19 caused by SARS-CoV-2 has resulted in millions of people being infected and thousands of deaths globally since November *** date,no unique therapeutic agent has been developed to slow the progression of this *** possessing antiviral traits the potential of bacteriocins to combat SARS-CoV-2 infection has not been fully *** review summarizes the mechanisms by which bacteriocins can be manipulated and implemented as effective virus entry blockers with infection suppression potential properties to highly transmissible viruses through comprehensive immune modulations that are potentially effective against *** antimicrobial peptides have been suggested as effective antiviral therapeutics and therapeutic supplements to prevent rapid virus *** review also provides a new insight into the cellular and molecular alterations which have made SARS-CoV-2 self-modified with diversified infection *** addition,the possible applications of antimicrobial peptides through both natural and induced mechanisms in infection prevention perspectives on changeable virulence cases are comprehensively *** attention is given to the antiviral mechanisms of the molecules along with their integrative use with synthetic biology and nanosensor technology for rapid *** bacteriocin based therapeutics with cutting-edge technologies might be potential substitutes for existing time-consuming and expensive approaches to fight this newly emerged global threat.

关键词： antimicrobial proteins antiviral profiling of bacteriocins antiviral therapeutics immunomodulation nanosensor technology mutated SARS-CoV-2

Anisotropic quintessence compact star in f(T)gravity with Tolman–Kuchowicz metric potentials

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Communications in Theoretical Physics 2024年第1期76卷 61-75页

作者： Piyali Bhar Farook Rahaman Shyam Das Somi aktar Abdelghani Errehymy Department of Mathematics Government General Degree College SingurHooghlyWest Bengal 712409India Department of Mathematics Jadavpur UniversityKolkata 700032West BengalIndia Department of Physics Malda College MaldaWest Bengal 732101India Astrophysics Research Centre School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa

To obtain analytically relativistic quintessence anisotropic spherical solutions in the f(T)paradigm is the primary objective of this *** do this,the pressure anisotropy condition is imposed,and we employ a metric potential of the Tolman–Kuchowicz(TK)*** also suppose that our current model incorporates a quintessence field characterized by a parameterωq,in addition to the anisotropic matter *** the presence of the parameterα,the field equations are modified by the choice of the f(T)*** f(T)gravity parameterαadds new components to the basic physical characteristics,such as density,pressure,subliminal sound velocity,surface redshift,etc,of the present *** selecting the compact star Her X-1 and varyingαfrom 0.5 to 2.5,we examined all the physical characteristics of the model parameter of the *** graphical process demonstrates that a more compact item is produced with greater values ofα.The hydrostatic equilibrium condition of the model is discussed,as well as the mass-radius relationship for our current model is obtained.

关键词： quintessence star f(T)gravity stability condition

A Novel LSB Steganography Technique for Enhancing Cloud Security

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Journal of Information Security 2024年第3期15卷 355-377页

作者： Ahsan Ullah Md. Inzamul Haque Md. Mokarom Hossain Md. Sadman Ahammad Mst. Nishita aktar Department of Computer Science and Engineering World University of Bangladesh Dhaka Bangladesh

Steganography is a technique that is frequently used to hide hidden information in multimedia artifacts including music, video, and images. In order to protect data saved in the cloud, this paper presents a steganography method for encrypting sound utilizing LSB-based computation. By using the least significant bit (LSB) of a byte to represent a message and then substituting each LSB bit with a binary message and encrypting a significant quantity of data. The proposed system uses the LSB technique of picture steganography, Multi-Level Encryption Algorithm (MLEA) and Two-Level Encryption Algorithm (TLEA) data encryption to give the highest level of cloud security. Compared to other current schemes, the performance of the suggested method is 1.732125% better on average.

关键词： Steganography LSB Cloud Computing Security Cryptography TLEA MLEA

Coccinia grandis:Phytochemistry,pharmacology and health benefits

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Clinical Traditional Medicine and Pharmacology 2024年第3期5卷 125-143页

作者： MdSabbir Hossain Ishrat Jahan Mumtasin Islam Jannatun Nayeem Tahseen Sharika Anzum Nusyba aktar Afrin Farjana Karim Mim Md.Kamrul Hasan Department of Biochemistry and Molecular Biology Tejgaon CollegeNational UniversityGazipur 1700Bangladesh Department of Public Health North South UniversityDhaka 1229Bangladesh

Background:Coccinia grandis(L.)Voigt,commonly known as Ivy gourd,is a plant of the Cucurbitaceae family that has been used in traditional medicinal systems for *** most common traditional use is managing diabetes mellitus which has been scientifically proven along with other pharmacological ***:This review aims to thoroughly explore the scientific evidence of various pharmacological activities of *** and its therapeutic ***:A thorough search of the literature was carried out to identify relevant research on *** the combination of the plants’scientific names,different keywords,such as“Coccinia grandis”“Coccinia indica”“tra-ditional medicine”“ethnobotany”“ethnomedicine”“phytochemistry”“bioactive compounds”“pharmacology”“health benefit”“side effect”“toxicity”and“clinical trial”,have been used for search using Boolean *** articles were strictly screened to maintain inclusion *** hundred and sixty-nine papers were eventually chosen for this review after a thorough examination of the retrieved articles that matched the inclusion and exclusion ***:*** was found to have a number of compounds that are biologically active and exhibit anti-diabetic,anti-dyslipidemic,anti-obesity,anti-oxidant,anti-inflammation,anti-cancer,analgesic,anti-oxidant,antinocicep-tive,antipyretic,anthelmintic,analgesic,spasmolytic,wound-healing,anti-ulcerogenic,anti-convulsant,hepato-protective and immunomodulatory activities without obvious side *** produced from the plant and different extracts of the plant show excellent anti-microbial ***:The scientific evidence encourages exploring more in-depth experimental studies regarding the phar-macological activities to develop *** as a novel therapeutic agent.

关键词： C.grandis Ivy gourd Cucurbitaceae Pharmacological activities Anti-diabetic Nanoparticles

Effects of resistivity on standing shocks in low angular momentum flows around black holes

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Research in Astronomy and Astrophysics 2021年第6期21卷 222-232页

作者： Chandra B.Singh Toru Okuda Ramiz aktar South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China Hakodate Campus Hokkaido University of EducationHachiman-Cho 1-2HakodateHokkaido 040-8567Japan Department of Astronomy Xiamen UniversityXiamen 361005China

We study two-dimensional low angular momentum flow around a black hole using the resistive magnetohydrodynamic module of PLUTO *** have been performed for the flows with parameters of specific angular momentum,specific energy and magnetic field which may be expected for the flow around Sgr A*.For flows with lower resistivityη=10^(-6)and 0.01,the luminosity and shock location on the equator vary *** power density spectra of luminosity variation show peak frequencies which correspond to the periods of 5×10^(5),1.4×10^(5)and 5×10^(4)*** quasi-periodic oscillations(QPOs)occur due to interaction between the outer oscillating standing shock and the inner weak shocks occurring at the innermost hot *** for cases with higher resistivityη=0.1 and 1.0,the high resistivity considerably suppresses the magnetic activity such as MHD turbulence and the flows tend to be steady and symmetric with respect to the *** steady standing shock is formed more outward compared with the hydrodynamical *** low angular momentum flow model with the above flow parameters and with low resistivity has a possibility to explain long-term flares of Sgr A*with frequencies~one per day and~5-10 days in the latest observations by Chandra,Swift and XMM-Newton monitoring of Sgr A*.

关键词： accretion accretion disks magnetohydrodynamics(MHD) methods:numerical shock waves Galaxy:center

Engineered chitosan for improved 3D tissue growth through Paxillin-FAK-ERK activation

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Regenerative Biomaterials 2020年第2期7卷 141-151页

作者： Md Abdul Kafi Khudishta aktar Mitsugu Todo Ravinder Dahiya BEST Group School of EngineeringUniversity of GlasgowGlasgow G128QQUK Department of Microbiology and Hygiene Bangladesh Agricultural UniversityMymensingh 2202Bangladesh Research Institute for Applied Mechanics Kyushu UniversityKasugaFukuokaJapan

Scaffold engineering has attracted significant attention for three-dimensional(3D)growth,prolifer-ation and differentiation of stem cells in *** available scaffolds suffer from issues such as poor ability for cell adhesion,migration and *** paper addresses these issues with 3D porous chitosan scaffold,fabricated and functionalized with cysteine-terminated Arg-Gly-Asp(Cys-RGD)tri-peptide on their *** study reveals that the compressive moduli of the scaffold is independent to RGD functionalization but shows dependence on the applied freezing temperature(TM)during the fabrication *** low freezing TM(-80℃)produces scaffold with high compressive moduli(14.64±1.38 kPa)and high TM(-30℃)produces scaffold with low compressive moduli(5.6±0.38 kPa).The Cys-RGD functionalized scaffolds lead to significant improvements in adhesion(150%)and proliferation(300%)of human mesenchymal stem cell(hMSC).The RGD-integrin coupling activates the focal adhesion signaling(Paxillin-FAK ERK)path-ways,as confirmed by the expression of p-Paxillin,p-FAK and p-ERK protein,and results in the observed improvement of cell adhesion and *** proliferation of hMSC on RGD func-tionalized surface was evaluated with scanning electron microscopy imaging and distribution though pore was confirmed by histochemistry of transversely sectioned *** hMSC adhe-sion and proliferation in scaffold with high compressive moduli showed a constant enhancement(with a slope value 9.97)of compressive strength throughout the experimental period of 28 *** improved cell adhesion and proliferation with RGD functionalized chitosan scaffold,together with their mechanical stability,will enable new interesting avenues for 3D cell growth and differen-tiation in numerous applications including regenerative tissue implants.

关键词： adhesion signaling chitosan hMSC porous scaffold proliferation Cys-RGD tssue engineering