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Investigation of the Phytochemicals, Antioxidant, and Antimicrobial Activity of the Andrographis paniculataLeaf and Stem Extracts

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Advances in Bioscience and Biotechnology 2017年第5期8卷 149-162页

作者： Shakil Ahmed Polash Tanushree Saha Md. sharif hossain Satya Ranjan Sarker Department of Biotechnology and Genetic Engineering Faculty of Biological Sciences Jahangirnagar University Dhaka Bangladesh Department of Textile Engineering Dhaka University of Engineering and Technology Gazipur Bangladesh

Andrographis paniculata (Kalmegh) has been considered as a medicinal shrub and used as a medicinal plant in the remote areas of Bangladesh. A. paniculata leaf and stem extracts were prepared using the polar (i.e., water, and 70% ethanol) and nonpolar (i.e., hexane) solvents. The phytochemical contents, total phenol contents (TPC), antioxidant activity, and antibacterial activity of all the extracts of A. paniculata leaf and stem were investigated. Both the gram-positive (i.e., Bacillus subtillis) and gram-negative (i.e., E. coli, and Salmonella typhi) strains of bacteria were used for the antibacterial activity assay of the sample extracts. The ethanolic stem extracts contained the maximum amount of TPC when compared to that of the leaf extracts. However, the aqueous stem extracts had the highest free radical scavenging activity in vitro. The extracts prepared from A. paniculata stem showed better antibacterial activity against all the strains of bacteria (i.e., E. coli, S. typhi, and B. subtillis) when compared to that of the leaf extracts. More specifically, the aqueous stem extract showed superior antibacterial effect against E. coli, and B. subtillis, and the zones of inhibition were 21 mm, and 29 mm in diameter, respectively. On the other hand, the ethanolic stem extract showed the maximum antibacterial activity against S. typhi and the zone of inhibition was 8.15 mm. The minimum inhibitory concentration (MIC) value and IC50 value for all the A. paniculata extracts were ~0.05 μg/μL, and ~1 μg/μL, respectively.

关键词： Andrographis paniculata Total Phenol Content Antioxidant Antimicrobial Zone of Inhibition

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Anisotropic extensions of isotropic Finch–Skea metric in the charged modified gravity

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Communications in Theoretical Physics 2024年第9期76卷 118-140页

作者： Tayyab Naseer M sharif Department of Mathematics and Statistics The University of Lahore1-Km Defence RoadLahore 54000Pakistan

In this study,we explore the Finch–Skea perfect fluid solution and extend its domain to three distinct anisotropic interior models within the framework of the f(R,T)theory,incorporating the influence of an electromagnetic *** assume a static spherical spacetime initially coupled with an isotropic matter *** then introduce a Lagrangian corresponding to an additional gravitating source,taking into account its role in inducing pressure anisotropy within the original fluid *** deriving the field equations for the combined matter setup,we applied a radial component transformation,which yielded two distinct systems of *** addition,we consider a charged exterior spacetime to determine the three constants associated with the Finch–Skea solution at the *** findings suggest that under certain parametric choices,all three resulting models exhibited physical relevance within this modified theory.

关键词： anisotropy modified gravity gravitational decoupling

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Advances in DNA methylation and its role in cytoplasmic male sterility in higher plants

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Journal of Integrative Agriculture 2024年第1期23卷 1-19页

作者： Atiqur Rahman Hasan Sofiur Rahman Shakil Uddin Naima Sultana Shirin Akhter Ujjal Kumar Nath Shamsun Nahar Begum Mazadul Islam Afroz Naznin Nurul Amin sharif Ahmed Akbar hossain Department of Genetics and Plant Breeding Bangladesh Agricultural UniversityMymensingh 2202Bangladesh Plant Breeding Division Bangladesh Institute of Nuclear AgricultureMymensingh 2202Bangladesh Tuber Crop Research Centre Bangladesh Agricultural Research Institute(BARI)Joydebpur 1701Bangladesh Horticulture Research Centre Bangladesh Agricultural Research Institute(BARI)Joydebpur 1701Bangladesh Biotechnology Division Bangladesh Agricultural Research Institute(BARI)Joydebpur 1701Bangladesh International Rice Research Institute Bangladesh OfficeDhaka 1213Bangladesh Division of Soil Science Bangladesh Wheat and Maize Research InstituteDinajpur 5200Bangladesh

The impact of epigenetic modifications like DNA methylation on plant phenotypes has expanded the possibilities for crop *** methylation plays a part in the regulation of both the chromatin structure and gene expression,and the enzyme involved,DNA methyltransferase,executes the methylation process within the plant *** regulating crucial biological pathways,epigenetic changes actively contribute to the creation of the ***,epigenome editing may assist in overcoming some of the drawbacks of genome editing,which can have minor off-target consequences and merely facilitate the loss of a gene’s *** drawbacks include gene knockout,which can have such off-target *** review provides examples of several molecular characteristics of DNA methylation,as well as some plant physiological processes that are impacted by these epigenetic changes in the *** also discuss how DNA alterations might be used to improve crops and meet the demands of sustainable and environmentally-friendly farming.

关键词： DNA methylation epigenetics CMS male sterility chromatin architecture gene expression higher plants

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Investigation of Ovarian Follicular Waves and Major Hormonal Profile in Red Chittagong Cattle

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Advances in Bioscience and Biotechnology 2020年第2期11卷 7-21页

作者： Saiful Islam Md. Ahsanul Kabir Md. Faizul hossain Miraz Effat Jahan Tamanna Satya Ranjan Sarker Zinia Islam S. M. Jahangir hossain sharif hossain Gautam Kumar Deb Department of Biotechnology and Genetic Engineering Jahangirnagar University Dhaka Bangladesh Biotechnology Division Bangladesh Livestock Research Institute Savar Dhaka Bangladesh

Red Chittagong Cattle (RCC) is one of the renowned varieties of cattle which is indigenous and most potential type of domestic animal genetic resource in Bangladesh with distinct phenotypic characteristics. Reproductive management might be a process for multiplying this cattle variety. Therefore, the goals of this study were to characterize the follicular waves of RCC and to determine the Progesterone (P4), Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) profile during three consecutive estrus cycle. Follicular wave emergence (Day 0) was identified using trans-vaginal ultrasound technique and follicular growth was then monitored from Day 0 to Day 23 during three consecutive estrus cycle and blood samples were collected. After measuring the growth and diameter of the follicles, hormonal assays of collected blood samples were performed using Enzyme Linked Immunosorbent Assay (ELISA). We found that, both RCC cows and heifers showed two waves inter-ovulatory intervals. The length of inter-ovulatory intervals and the diameter of the ovulatory follicle of RCC cows and heifers were slightly different from each other. The identification of the dominant follicle was confirmed from the start of its deviation from other subordinate follicles till it reached to the maximum diameter and identified as dominant follicle which increases linearly for approximately six days (growing phase). This dominant follicle is remained approximately same size for five days (static phase), and then begins to regress (regressing phase) decreasing the antral diameter. The follicular waves are first detectable as 4 - 5 mm follicles approximately at day 0 and day 10 both for RCC cows and heifers which showed two waves inter-ovulatory intervals. The circulating varied concentrations of LH, FSH and P4 were determined using ELISA in case of both cows and heifers and the concentration curves followed the similar pattern of change during the estrus cycle. Hence, the knowledge about ovaria

关键词： Red Chittagong Cattle Ovarian Follicles Progesterone Follicle Stimulating Hormone Luteinizing Hormone ELISA

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Model Predictive Control based Motion Cueing Algorithm for Driving Simulator

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Journal of Systems Science and Systems Engineering 2024年第5期33卷 607-626页

作者： Ayesha Hameed Ali Soltani sharif Abadi Andrzej Ordys Institute of Automatic Control and Robotics Warsaw University of TechnologyWarsawPoland Institute of Electronic Systems Warsaw University of TechnologyWarsawPoland

Thanks to the emerging integration of algorithms and simulators, recent Driving Simulators (DS) find enormous potential in applications like advanced driver-assistance devices, analysis of driver’s behaviours, research and development of new vehicles and even for entertainment purposes. Driving simulators have been developed to reduce the cost of field studies, allow more flexible control over circumstances and measurements, and safely present hazardous conditions. The major challenge in a driving simulator is to reproduce realistic motions within hardware constraints. Motion Cueing Algorithm (MCA) guarantees a realistic motion perception in the simulator. However, the complex nature of the human perception system makes MCA implementation challenging. The present research aims to improve the performance of driving simulators by proposing and implementing the MCA algorithm as a control problem. The approach is realized using an actual vehicle model integrated with a detailed model of the human vestibular system, which accurately reproduces the driver’s perception. These perception motion signals are compared with simulated ones. A 2-DOF stabilized platform model is used to test the results from the two proposed control strategies, Proportional Integrator and Derivative (PID) and Model Predictive Control (MPC).

关键词： Driving simulator motion cueing algorithm control theory model predictive control PID

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Investigation of the Phytoconstituents and Antioxidant Activity of Diospyros malabaricaFruit Extracts

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Advances in Bioscience and Biotechnology 2019年第12期10卷 431-454页

作者： Razib Datta Shubhra Shakil Ahmed Polash Tanushree Saha Ashraful Hasan sharif hossain Zinia Islam Satya Ranjan Sarker Department of Biotechnology and Genetic Engineering Jahangirnagar University Dhaka Bangladesh Department of Textile Engineering Dhaka University of Engineering and Technology Gazipur Bangladesh Department of Biochemistry and Molecular Biology Jahangirnagar University Dhaka Bangladesh

Diospyros malabarica (Deshi Gab) belonging to the family “Ebenaceae” grows well in the humid tropical climate of Bangladesh. In order to investigate the phytoconstituents both qualitatively and quantitatively, the seed and flesh extracts of D. malabarica were prepared using two polar solvents (i.e., water and 70% ethanol) and a nonpolar solvent (i.e., hexane). The maximum yield was obtained for aqueous and ethanolic seed extracts indicating that most of the phytoconstituents present in D. malabarica fruit are polar. The qualitative phytochemical analysis of the extracts revealed the presence of diverse amount of phytoconstituents in the extracts. On the other hand, the quantitative phytochemical analysis for phenols, tannins, flavonoids, alkaloids, saponin, proteins, reducing sugar and vitamin C revealed that the maximum amount of phenols, tannins, flavonoids and reducing sugar were present in aqueous seed extract. However, the maximum amount of total protein and vitamin C was found in ethanolic seed extract. D. malabarica seed powder contained more amount of alkaloids (i.e., 13.6%) than that of flesh (i.e., 3.4%). However, the content of saponin was more in flesh extract (0.74%) when compared to that of seed extract (0.42%). In vitro antioxidant properties of the extracts were also investigated by DPPH free radical scavenging assay, FRAP assay and reducing power assay. The highest antioxidant activity was observed for aqueous seed extract followed by the ethanolic seed, ethanolic flesh, and aqueous flesh extracts. The lowest antioxidant activity was obtained for hexane flesh extract. Furthermore, the lowest (i.e., 44.70 μg/ml) as well as the highest (2359.66 μg/ml) IC50 values were obtained for aqueous seed and hexane flesh extracts, respectively.

关键词： Diospyros malabarica Phytochemical Assay Total Phenol Content Total Tannin Content Total Flavonoid Content Antioxidant Activity

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Ga(X)N/Si nanoarchitecture:An emerging semiconductor platform for sunlight-powered water splitting toward hydrogen

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Frontiers in Energy 2024年第1期18卷 56-79页

作者： Yixin LI sharif Md.SADAF Baowen ZHOU Key Laboratory for Power Machinery and Engineering of the Ministry of Education Research Center for Renewable Synthetic FuelSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Centre Energie Matériaux et TélécommunicationsInstitut National de la Recherche Scientifique(INRS)-Universitédu Québec1650 Boulevard Lionel-BouletVarennesQuébec J3X1S2Canada

Sunlight-powered water splitting presents a promising strategy for converting intermittent and virtually unlimited solar energy into energy-dense and storable green *** the pioneering discovery by Honda and Fujishima,considerable efforts have been made in this research *** various materials developed,Ga(X)N/Si(X=In,Ge,Mg,etc.)nanoarchitecture has emerged as a disruptive semiconductor platform to split water toward hydrogen by *** paper introduces the characteristics,properties,and growth/synthesis/fabrication methods of Ga(X)N/Si nanoarchitecture,primarily focusing on explaining the suitability as an ideal platform for sunlight-powered water splitting toward green hydrogen *** addition,it exclusively summarizes the recent progress and development of Ga(X)N/Si nanoarchitecture for photocatalytic and photoelectrochemical water ***,it describes the challenges and prospects of artificial photosynthesis integrated device and system using Ga(X)N/Si nanoarchitectures for solar water splitting toward hydrogen.

关键词： Ga(X)N/Si nanoarchitecture artificial photosynthesis water splitting solar toward hydrogen

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First Report of Pseudopestalotiopsis theae Causing Aloe vera Leaf Spot Disease in Bangladesh

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American Journal of Plant Sciences 2022年第2期13卷 193-204页

作者： Md. Sabbir Ahmmed Md. Maniruzzaman Sikder Satya Ranjan Sarker Md. sharif hossain Razib Datta Shubhra Nuhu Alam Department of Botany Faculty of Biological Sciences Jahangirnagar University Savar Bangladesh Department of Biotechnology and Genetic Engineering Faculty of Biological Sciences Jahangirnagar University Savar Bangladesh

Aloe vera (L.) Burm.f. is one of the important medicinal plants, has been commercially cultivated in the Northern part of Bangladesh. An experiment was conducted to detect A. vera leaf disease collected from Natore district, Bangladesh. Fungal leaf spot disease caused by Pseudopestalotiopsis theae (Sawada) Maharachch., K.D. Hyde & Crous was identified through morphological features and sequencing of internal transcribed spacer region of ribosomal DNA. After submitting nucleotide sequences to NCBI, we received an accession number MH333081.1: Pseudopestalotiopsis theae. The growth pattern of the isolated fungal pathogen was evaluated on different solid culture media, at different temperature and light conditions. The results showed the maximum mycelial growth of the fungus on the Richard Agar medium under the complete dark condition at 25°C. We evaluated fungal antagonists against the isolated pathogenic fungus, in which Trichoderma asperellum showed optimistic results. Synthetic fungicides—Tilt 250EC and Ridomil Gold completely inhibited the studied fungus’s vegetative growth. Pseudopestalotiopsis theae causing A. vera leaf spot disease in Bangladesh is a new record to the best of our knowledge.

关键词： Fungal Biology Molecular Growth Characters Bio-Control Agents Fungicides

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Investigation of the Phytoconstituents and Bioactivity of Various Parts of Wild Type and Cultivated Phyllanthus emblicaL.

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Advances in Bioscience and Biotechnology 2017年第7期8卷 211-227页

作者： Ratna Mondal Shakil Ahmed Polash Tanushree Saha Zinia Islam Md. Maniruzzaman Sikder Nuhu Alam Md. sharif hossain Satya Ranjan Sarker Department of Biotechnology and Genetic Engineering Jahangirnagar University Savar Dhaka Bangladesh Department of Textile Engineering Dhaka University of Engineering and Technology Gazipur Bangladesh Department of Botany Jahangirnagar University Savar Dhaka Bangladesh

Phyllanthus emblica L. belonging to the family Euphorbiaceae is a common medicinal plant in Bangladesh. In order to evaluate the phytoconstituents and bioactivity of various parts of P. emblica, both the wild type (i.e., small) and cultivated (i.e., big) fruits were collected from the local market of Bangladesh and six ethanolic extracts were prepared from various parts of the collected fruits for this current study. A comparative analysis of the phytochemical compositions and various bioactivities especially antibacterial, antifungal, and antioxidant activity of the six ethanolic extracts were accomplished. The qualitative phytochemical analysis of plant extracts revealed the presence of large amounts of proteins, carbohydrates, phenolic compounds, glycosides, alkaloids, coumarins, flavonoids, tannins, saponins and resins etc. The maximum antioxidant activity was observed for wild type P. emblica seed extracts and the minimum activity was observed for cultivated flesh extracts. Moreover, among the samples the wild type P. emblica extracts have excellent amount of total phenol contents and the highest free radical scavenging activity. It is also found that P. emblica samples were active against both gram-positive (i.e., B. subtilis) and gram-negative (i.e., E. coli, and S. typhi) bacteria. The highest antibacterial activity was achieved in the wild type P. emblica seed extracts against both pathogenic (S. typhi) and non-pathogenic bacterial strains (E. coli, and B. subtilis). These samples showed almost no activity against Fusarium sp. fungus.

关键词： Phyllanthus emblica Total Phenol Content Antioxidant Activity Antimicrobial Activity Zone of Inhibition and Antifungal Activity

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Toward carbon neutrality by artificial photosynthesis

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Frontiers in Energy 2024年第1期18卷 54-55页

作者： Baowen ZHOU Minhua SHAO sharif Md.SADAF Shuhui SUN Key Laboratory for Power Machinery and Engineering of the Ministry of Education Research Center of Renewable Synthetic FuelSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Department of Chemical and Biological Engineering Energy InstituteThe Hong Kong University of Science and TechnologyHong KongChina Institut National de la Recherche Scientifique(INRS)-CenterÉnergie Matériaux Télécommunications VarennesQuebec J3X 1P7Canada

CO_(2)is not only the primary cause of climate change but also an abundant and recyclable carbon *** breakthrough in emerging disruptive technologies such as carbon capture and storage(CCS),power-to-X,and direct air capture(DAC)is fundamental to achieving carbon *** these technologies,artificial photosynthesis offers an attractive method for recycling carbon dioxide and water into fuels and chemicals using solar energy(CO_(2)+H_(2)O+sunlight→fuels+chemicals).It holds great promise for addressing the critical challenges associated with elevated CO_(2)concentrations and securing a sustainable supply of fuels and chemicals for economic sectors.

关键词： neutral holds breakthrough

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