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A novel neuroprotective method against ischemic stroke by accelerating the drainage of brain interstitial fluid

Science China Life Sciences 2024年第10期67卷 2213-2223页

作者： Jingge Lian Liu Yang Hanbo Tan shaoyi su Leonor Serrano Lopes Fangxiao Cheng Junhao Yan Yu Fu Wanyi Fu Zhaoheng Xie Jianfei sun Jicong Zhang Zhiqian Tong Yajuan Gao Hongbin Han Department of Radiology Peking University Third Hospital Beijing Key Laboratory of Magnetic Resonance Imaging Technology Institute of Medical Technology Peking University Health Science Center Department of Informatics Technical University of Munich Department of Anatomy and Histology School of Basic Medical SciencesPeking University Department of Neurology Peking University Third Hospital Department of Electronic Engineering Tsinghua University State Key Laboratory of Bioelectronics School of Biological Science and Medical EngineeringSoutheast University School of Biological Science and Medical Engineering Beihang University Key Laboratory of Alzheimer's Disease of Zhejiang Province Institute of AgingSchool of Mental HealthWenzhou Medical University NMPA Key Laboratory for Evaluation of Medical Imaging Equipment and Technique

Ischemic stroke is a leading cause of death and disability worldwide. Inflammatory response after stroke determines the outcome of ischemic injury. A recent study has reported an efficient method, epidural arterial implantation(EAI), for accelerating interstitial fluid(ISF)drainage, which provides a promising strategy to clear pro-inflammatory cytokines in the brain extracellular space(ECS). In this study, the method of EAI was modified(m-EAI) to control its function of accelerating the ISF drainage at different time points following ischemic attack. The neuroprotective effect of m-EAI on ischemic stroke was evaluated with the transient middle cerebral artery occlusion(tMCAO)rat model. The results demonstrated the accumulation of IL-1β, IL-6, and TNF-α was significantly decreased by activating m-EAI at 7 d before and immediately after ischemic attack in tMCAO rats, accompanied with decreased infarct volume and improved neurological function. This study consolidates the hypothesis of exacerbated ischemic damage by inflammatory response and provides a new perspective to treat encephalopathy via brain ECS. Further research is essential to investigate whether m-EAI combined with neuroprotective drugs could enhance the therapeutic effect on ischemic stroke.

关键词： ischemic stroke brain extracellular space interstitial fluid modified epidural arterial implantation

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Flight Time Minimization of UAV for Cooperative Data Collection in Probabilistic LoS Channel

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China Communications 2024年第2期21卷 210-226页

作者： Yan Li shaoyi Xu Yunpu Wu Dongji Li School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100044China School of Electrical Engineering and Electronic Information Xihua UniversityChengdu 610039China

This paper investigates the data collection in an unmanned aerial vehicle(UAV)-aided Internet of Things(IoT) network, where a UAV is dispatched to collect data from ground sensors in a practical and accurate probabilistic line-of-sight(LoS) channel. Especially, access points(APs) are introduced to collect data from some sensors in the unlicensed band to improve data collection efficiency. We formulate a mixed-integer non-convex optimization problem to minimize the UAV flight time by jointly designing the UAV 3D trajectory and sensors’ scheduling, while ensuring the required amount of data can be collected under the limited UAV energy. To solve this nonconvex problem, we recast the objective problem into a tractable form. Then, the problem is further divided into several sub-problems to solve iteratively, and the successive convex approximation(SCA) scheme is applied to solve each non-convex subproblem. Finally,the bisection search is adopted to speed up the searching for the minimum UAV flight time. Simulation results verify that the UAV flight time can be shortened by the proposed method effectively.

关键词： data collection flight time probabilistic line-of-sight channel unlicensed band unmanned aerial vehicle

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Virtual source approach for maximizing resolution in high-penetration gamma-ray imaging

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Matter and Radiation at Extremes 2024年第3期9卷 19-30页

作者： Yuchi Wu shaoyi Wang Bin Zhu Yonghong Yan Minghai Yu Gang Li Xiaohui Zhang Yue Yang Fang Tan Feng Lu Bi Bi Xiaoqin Mao Zhonghai Wang Zongqing Zhao Jingqin su Weimin Zhou Yuqiu Gu National Key Laboratory of Plasma Physics Laser Fusion Research CenterCAEPMianyangSichuan 621900China College of Physics Sichuan UniversityChengdu 610065China

High-energy gamma-ray radiography has exceptional penetration ability and has become an indispensable nondestructive testing(NDT)tool in various *** high-energy photons,point projection radiography is almost the only feasible imaging method,and its spatial resolution is primarily constrained by the size of the gamma-ray *** conventional industrial applications,gamma-ray sources are commonly based on electron beams driven by accelerators,utilizing the process of bremsstrahlung *** size of the gamma-ray source is dependent on the dimensional characteristics of the electron *** research has been conducted on various advanced accelerator technologies that have the potential to greatly improve spatial resolution in *** our investigation of laser-driven gamma-ray sources,a spatial resolution of about 90μm is achieved when the areal density of the penetrated object is 120 g/cm^(2).A virtual source approach is proposed to optimize the size of the gamma-ray source used for imaging,with the aim of maximizing spatial *** this virtual source approach,the gamma ray can be considered as being emitted from a virtual source within the convertor,where the equivalent gamma-ray source size in imaging is much smaller than the actual emission *** the basis of Monte Carlo simulations,we derive a set of evaluation formulas for virtual source scale and gamma-ray emission *** optimal conditions,the virtual source size can be as small as 15μm,which can significantly improve the spatial resolution of high-penetration imaging to less than 50μm.

关键词： resolution approach utilizing

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Challenges and strategies of chlorine inhibition in anode systems for seawater electrolysis

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Science China Chemistry 2024年第10期67卷 3198-3208页

作者： Chuqiang Huang Zhouzhou Wang Shaojun Cheng Yunpeng Liu Binglu Deng shaoyi Xu Luo Yu Ying Yu School of Materials Science and Hydrogen Energy Foshan University Institute of Nanoscience and Nanotechnology College of Physical Science and TechnologyCentral China Normal University Department of Physics and Texas Center for superconductivity at the University of Houston (TcsuH) University of Houston Laboratory of Solar Fuel Faculty of Materials Science and ChemistryChina University of Geosciences

Seawater electrolysis for green hydrogen production is one of the key technologies for achieving carbon neutrality. However, in anode systems, the chloride ions（Cl-） in seawater will trigger an undesired chlorine evolution reaction（CER） that competes with an oxygen evolution reaction（OER）, resulting in inferior OER activity and selectivity. Besides, the corrosive Cl-and its derivative products will corrode anodes during seawater electrolysis, leading to poor stability. Therefore, great efforts have been devoted to developing efficient strategies for chlorine inhibition to improve the activity, selectivity, and stability of anode materials. Herein, focusing on chlorine inhibition, we present a mini review to comprehensively and concisely summarize the recent progress in anode systems for boosting seawater electrolysis. In particular, two strategies of physical and chemical regulation to inhibit Cl-are summarized in some representative cases. Finally, some challenges and future opportunities in anode systems for seawater electrolysis are prospected. This mini review aims to shed light on designing highly efficient anode materials for seawater electrolysis.

关键词： seawater electrolysis anode systems chlorine inhibition physical regulation chemical regulation

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运营商面向物流行业综合解决方案的探讨

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电信科学 2009年第10期25卷 6-9页

作者：林涛苏少毅余冬苹中国电信股份有限公司广东研究院广州510630

随着电信技术的发展,呼叫中心、物流信息系统、定位及调度中心、RFID、手持信息终端等信息技术在物流行业得到越来越广泛的应用,但仍存在应用系统分散、信息孤岛、投资成本过高、维护困难等问题。面对这种形势,本文在深入分析物流行业... 详细信息

随着电信技术的发展,呼叫中心、物流信息系统、定位及调度中心、RFID、手持信息终端等信息技术在物流行业得到越来越广泛的应用,但仍存在应用系统分散、信息孤岛、投资成本过高、维护困难等问题。面对这种形势,本文在深入分析物流行业生产运营模式、信息化需求的基础上,结合国内各主要电信运营商的实践经验,探讨关于制定物流行业综合解决方案的思路与关键点,以期为运营商在物流行业的业务拓展提供参考。

关键词：物流信息化解决方案

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高校空中乘务专业人才培育的研究与实践——基于职业素养

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科教文汇 2020年第26期 105-106页

作者：苏劭忆中原工学院信息商务学院河南郑州450007

我国民航业正处在高速发展阶段,间接导致对空中乘务员的需求增大。同时,民航运输服务业的竞争也日渐激烈,对空中乘务员综合素质的要求大大提高。该文基于职业素养,结合高校实际情况,通过精心编制培育方案、构建完善的课程体系、第二课... 详细信息

我国民航业正处在高速发展阶段,间接导致对空中乘务员的需求增大。同时,民航运输服务业的竞争也日渐激烈,对空中乘务员综合素质的要求大大提高。该文基于职业素养,结合高校实际情况,通过精心编制培育方案、构建完善的课程体系、第二课堂等模块,简要分析当前环境下高校空中乘务专业人才培养模式。

关键词：空乘人才培育改革优化

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南宁市新一代暴雨强度公式与暴雨雨型研究

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气象研究与应用 2017年第2期38卷 1-5,9页

作者：周绍毅罗红磊苏志李强广西气象服务中心南宁530022 广西气候中心南宁530022

利用南宁气象站1953—2014年共62a的逐分钟降雨资料,建立南宁市暴雨强度公式和重现期2a历时30、60、90、120、150、180min以5min为单位时段的设计暴雨雨型。结果表明:(1)P-Ⅲ分布曲线对南宁市各历时降雨量的拟合效果最好。(2)采用P-Ⅲ... 详细信息

利用南宁气象站1953—2014年共62a的逐分钟降雨资料,建立南宁市暴雨强度公式和重现期2a历时30、60、90、120、150、180min以5min为单位时段的设计暴雨雨型。结果表明:(1)P-Ⅲ分布曲线对南宁市各历时降雨量的拟合效果最好。(2)采用P-Ⅲ分布、最小二乘法参数组合方法计算南宁市暴雨强度公式误差较小。(3)历时30min的设计暴雨雨型雨峰位置处于整场降雨过程的1/2分位,历时60-180min的雨峰位置基本处于整场降雨过程的1/3分位。雨峰处降雨强度随着历时的增加而增加。

关键词：暴雨强度雨峰暴雨雨型南宁市

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On-chip ultrafast stackable dielectric laser positron accelerator

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Chinese Physics B 2024年第3期33卷 350-354页

作者：孙斌何阳帆潘晨浩樊思劼王度王少义赵宗清 Department of Plasma Physics and Fusion Engineering School of Nuclear Science and TechnologyUniversity of Science and Technology of ChinaHefei 230026China National Key Laboratory of Plasma Physics Research Center of Laser FusionChina Academy of Engineering PhysicsMianyang 621900China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China State Key Laboratory of High Field Laser Physics and Chinese Academy of Sciences Center for Excellence in Ultra-Intense Laser Science Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Department of Engineering Physics Tsinghua UniversityBeijing 100084China The Institute of Technological Sciences Wuhan UniversityWuhan 430072China

We present a first on-chip positron accelerator based on dielectric laser *** innovative approach significantly reduces the physical dimensions of the positron acceleration apparatus,enhancing its feasibility for diverse *** utilizing a stacked acceleration structure and far-infrared laser technology,we are able to achieve a seven-stage acceleration structure that surpasses the distance and energy gain of using the previous dielectric laser acceleration ***,we are able to compress the positron beam to an ultrafast sub-femtosecond scale during the acceleration process,compared with the traditional methods,the positron beam is compressed to a greater *** also demonstrate the robustness of the stacked acceleration structure through the successful acceleration of the positron beam.

关键词： dielectric laser accelerator positron accelerator high gradient accelerator inverse Cherenkov effect

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Research Progress of High Entropy Ceramic Materials

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Research and Application of Materials Science 2024年第1期6卷 16-22页

作者： Song WU Shikai LIU Jialin WANG Bibo HAN shaoyi SHEN Zhigang YU Zhaobo ZHANG Xinhua ZHENG School of Materials Science and Engineering Henan University of TechnologyZhengzhouHenan450001China

High-entropy materials(HEMs)have better mechanical,thermal,and electrical properties than traditional materials due to their special"high entropy effect".They can also adjust the performance of high entropy ceramics by adjusting the proportion of raw materials,and have broad application prospects in many *** article provides a review of the high entropy effect,preparation methods,and main applications of high entropy ceramic materials,especially exploring relevant research on high entropy perovskite *** is expected to provide reference for the promotion of scientific research and the development of further large-scale applications of high-entropy ceramic materials.

关键词： High-entropy ceramic materials high entropy effect preparation method perovskite structure research prog

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“智慧+食品监管”:发展历程、应用现状与未来方向

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食品科学技术学报 2024年第3期42卷 1-10页

作者：左敏王菲宋绍义颜文婧戴欣然北京工商大学农产品质量安全追溯技术及应用国家工程研究中心北京100048 北京物资学院北京101149 北京工商大学食品与健康学院北京100048 北京工商大学计算机与人工智能学院北京100048

大食物观为食品产业的未来发展提出了新的需求。随着食品产业的扩大和升级,影响食品安全的因素将变得越来越复杂,因而带来更为艰巨的食品安全风险防控任务。只有保障业态安全,食品产业才能健康和顺利发展。当前,有限的监管资源和力量与... 详细信息

大食物观为食品产业的未来发展提出了新的需求。随着食品产业的扩大和升级,影响食品安全的因素将变得越来越复杂,因而带来更为艰巨的食品安全风险防控任务。只有保障业态安全,食品产业才能健康和顺利发展。当前,有限的监管资源和力量与食品产业中繁重复杂的监管任务之间的矛盾日益凸显,传统的监管手段和方式难以满足食品产业的高质量发展需求。数据驱动下的计算机科学和智能技术为食品监管提供了技术切入点。在食品产业链中,实时采集各种信息形成“数据智能”,发展食品行业的智慧监管技术,有助于建设规范有序、协同高效的食品产业生态环境,为食品行业高质量发展提供保障。介绍了食品产业中智慧监管从初始到繁荣的发展历程,分析了智能技术在食品全产业链和食品监管体系数字化建设中的应用,指出了以安全为底线,以品质监测、营养分析、风味评估为新导向的食品智慧监管未来发展方向,探讨了食品行业智慧监管面临的机遇和挑战,希望为食品监管的智能化和高质量发展提供技术参考。

关键词：人工智能食品监管安全保障风险防范大食物观

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