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Fufang E’jiao Jiang’s effect on immunity,hematopoiesis,and angiogenesis via a systematic“compound-effect-target”analysis

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Food Science and Human Wellness 2024年第5期13卷 2813-2832页

作者： xiang Li xiao Xu Ying Dong Shusheng Fan Xueyang Ren Yuan Zheng Jiamu ma Feng Zhang Qingyue Deng xianxian Li Yingyu He Mengyu Sun Wei Liu Mengxia Li Qing xia Yan Zhang Gaimei She School of Chinese materia Medica Beijing University of Chinese MedicineBeijing 102488China Biology Institute Qilu University of Technology(Shandong Academy of Sciences)Jinan 250103China National Engineering Research Center for Gelatin-based Traditional Chinese Medicine Dong-E-E-Jiao Co.Ltd.Liaocheng 252201China

Fufang E’jiao Jiang(FEJ)as a healthy food consisting of medicine food homology materials approved by China’s Ministry of Health has been extensively applied to replenish qi and nourish blood,and it has a positive impact on women’s *** find out the material basis and mechanism of FEJ,a systematic“compoundeffect-target”analysis including chemical composition resolution,zebrafish,network pharmacology,molecular docking,transcriptome,and bibliometric analysis was adopted.124 chemical components including ginsenosides,and phenylethanoid glycosides in FEJ were discovered,and effects of FEJ on promoting the generation of immune cells,erythropoiesis and angiogenesis in zebrafish were *** on network pharmacology,molecular docking and in vivo activity assay,6 compounds including jionoside A1,isoacteoside,echinacoside,acteoside,lobetyolin,and rehmannioside D were identified as active components of *** data showed that several pathways such as complement and coagulation cascades,ECM-receptor interaction,and PI3K-Akt signaling pathway were associated with proangiogenic effect of FEJ.19 common targets were obtained through combined analysis of network pharmacology and transcriptomics,and 5 targets of them were verified by *** bibliometric analysis of these common targets revealed that FEJ was related to energy metabolism,pathway in cancer,etc.,which was consistent with the results of network pharmacology and *** studies suggested that FEJ could replenish qi and nourish blood through multi-compound and multi-targets.

关键词： Fufang E’jiao Jiang Zebrafish(Danio rerio) Network pharmacology Transcriptome Bibliometrics

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Angle-resolved photoemission study of NbGeSb with non-symmorphic symmetry

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Chinese Physics B 2024年第2期33卷 464-470页

作者：马欢谭宁吴徐传李满王义炎路洪艳夏天龙王善才 Department of Physics Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education)Renmin University of ChinaBeijing 100872China Beijing Key Laboratory of Opto-Electronic Functional materials&Micro-Nano Devices Renmin University of ChinaBeijing 100872China School of Information Network Security People’s Public Security University of ChinaBeijing 100038China Institute of Physical Science and Information Technology Anhui UniversityHefei 230601China School of Physics and Physical Engineering Qufu Normal UniversityQufu 273165China

We investigate the electronic structure of NbGeSb with non-symmorphic *** employ angle-resolved photoemission spectroscopy(ARPES)to observe and identify the bulk and surface states over the Brillouin *** utilizing high-energy photons,we identify the bulk Fermi surface and bulk nodal line along the direction X–R,while the Fermi surface of the surface state is observed by using low-energy *** observe the splitting of surface bands away from the high-symmetry point *** density functional theory calculations on bulk and 1 to 5-layer slab models,as well as spin textures of NbGeSb,verify that the band splitting could be attributed to the Rashba-like spin–orbit coupling caused by space-inversion-symmetry breaking at the *** splitted surface bands cross with each other,forming two-dimensional Weyl-like crossings that are protected by mirror *** findings provide insights into the two-dimensional topological and symmetry-protected band inversion of surface states.

关键词： non-symmorphic symmetry nodal line splitting of surface bands angle-resolved photoemission spectroscopy

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基于铝基含能配合物及CL-20含能微芯片的制备及表征

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火炸药学报 2024年第5期47卷 438-444,I0004页

作者：孟珂娟马小霞李宇翔张开黎香港城市大学工学院机械工程系中国香港999077 北京理工大学机电学院北京100081

为提高含能微芯片的能量特性和燃烧特性,推进其在微推进器、微驱动器、微毁伤器等装置中的应用,通过在铜箔上原位生长含能配位聚合物(ECP)、电子束沉积n-Al及重结晶CL-20的方法制备了ECP@Al@CL-20的含能阵列,采用SEM、XRD、TG/DSC及高... 详细信息

为提高含能微芯片的能量特性和燃烧特性,推进其在微推进器、微驱动器、微毁伤器等装置中的应用,通过在铜箔上原位生长含能配位聚合物(ECP)、电子束沉积n-Al及重结晶CL-20的方法制备了ECP@Al@CL-20的含能阵列,采用SEM、XRD、TG/DSC及高速摄影等表征方法对其微观形貌、物相组成、热分解特性、燃烧性能及贮存寿命进行了测试与分析。在此基础上,将其与微机电系统(MEMS)集成制得了功能性的ECP@Al@CL-20含能微芯片,并对含能微芯片进行了电容点火测试。结果表明,由于ECP的导热系数低,使ECP@Al@CL-20含能阵列从外到内的传热效率降低,导致放热峰温相比纯CL-20提高了8.5℃,从而提高了ECP@Al@CL-20的热稳定性;ECP@Al@CL-20含能阵列具有优异的燃烧性能,自持燃烧时间(340 ms)远大于ECP@Al的自持燃烧时间(120 ms),含能微芯片可在15 mJ的输入能量下激发。

关键词：含能配位聚合物微机电系统纳米铝 CL-20 微加热器含能微芯片 ECP MEMS

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低共熔溶剂辅助制备空心球状钙钛矿型高熵氧化物及高倍率储锂性能

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化学学报 2024年第3期82卷 303-313页

作者：鲍梦凡陈诗洁邵霞邓慧娟冒爱琴檀杰安徽工业大学材料科学与工程学院马鞍山243032 安徽工业大学材料科学与工程学院先进陶瓷研究中心马鞍山243032

近年来高熵氧化物因其独特的四大效应,作为高性能的锂离子电池(LIBs)负极材料受到广泛关注.本研究借助于形貌和缺陷调控策略调控晶格畸变和氧空位,以金属硝酸盐为金属源,葡萄糖和尿素为低共熔溶剂,采用基于低共熔溶剂辅助的固相反应法... 详细信息

近年来高熵氧化物因其独特的四大效应,作为高性能的锂离子电池(LIBs)负极材料受到广泛关注.本研究借助于形貌和缺陷调控策略调控晶格畸变和氧空位,以金属硝酸盐为金属源,葡萄糖和尿素为低共熔溶剂,采用基于低共熔溶剂辅助的固相反应法制备了La(Co_(0.2)Cr_(0.2)Fe_(0.2)Mn_(0.2)Ni_(0.2))O_(3)以及Li、Na元素掺杂的La(Li_(1/6) Co_(1/6)Cr_(1/6)Fe_(1/6)Mn_(1/6)Ni_(1/6))O_(3)和La(Na_(1/6)Co_(1/6)Cr_(1/6)Fe_(1/6)Mn_(1/6)Ni_(1/6))O_(3)钙钛矿型高熵氧化物纳米晶粉体.测试结果表明:所制备的高熵氧化物均为单相钙钛矿结构,其形貌为具有介孔结构的空心球状且各组成元素分布均匀.储锂性能表明:La(Li_(1/6)Co_(1/6)Cr_(1/6)Fe_(1/6)Mn_(1/6)Ni_(1/6))O_(3)电极展示了最高的比容量(电流密度200 ma·g^(-1)下循环100圈的可逆比容量为410.0mah·g^(-1))和优异的倍率性能(100 ma·g^(-1)电流密度下可逆比容量为342 mah·g^(-1),3000 ma·g^(-1)电流密度下可逆比容量为169.43 mah·g^(-1),容量保持率为49.4%).虽然La(Li_(1/6)Co_(1/6)Cr_(1/6)Fe_(1/6)Mn_(1/6)Ni_(1/6))O_(3)具有略小的D_(Li)~+,但适当的晶格畸变、氧空位和较高的比表面积使其具有更高的电导率(0.072 S·cm^(-1))以及更小的阻抗,从而显著提升了材料的比容量和倍率性能.该项工作为开发出高性能LIBs的先进负极材料提供了新的设计理念和思路.

关键词：负极材料钙钛矿型高熵氧化物掺杂缺陷工程储锂性能

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基于遗传算法的斜拉桥基准模型参数修正方法

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湖南大学学报（自然科学版） 2024年第5期51卷 95-105页

作者：马海英邱媛夏烨赖明辉李清岭同济大学土木工程学院上海200092 四川省公路规划勘察设计研究院有限公司四川成都610041 上海市城市建设设计研究总院(集团)有限公司上海200092

健康监测对于斜拉桥结构全寿命的安全使用十分重要,而使用传感器采集斜拉桥数据进行健康监测存在盲区.结合Benchmark模型对桥梁结构进行监测,能够在给定状态下,比较和评价不同的健康监测方法标准,对桥梁的设计、运营以及管养等方面有重... 详细信息

健康监测对于斜拉桥结构全寿命的安全使用十分重要,而使用传感器采集斜拉桥数据进行健康监测存在盲区.结合Benchmark模型对桥梁结构进行监测,能够在给定状态下,比较和评价不同的健康监测方法标准,对桥梁的设计、运营以及管养等方面有重要意义.本文基于背景工程,提出用于斜拉桥结构健康监测的基准模型.首先,使用matlab建立斜拉桥的鱼骨梁简化有限元模型,并建立斜拉桥的板壳单元精细模型,作为简化补充模型和模态矫正模型;其次,采用正交试验设计,对建模过程中的待修正参数进行斜拉桥动力特性参数的显著性分析;最后,基于遗传算法对模型参数进行修正,提出了动态自适应技术和并列选择的方法优化遗传算法结构,干涉遗传选择过程,并赋予初始种群更高的离散性,与调用GA函数的方法对模型进行修正进行比较,验证了改进后的遗传算法具有更高的计算效率,模态参数误差较小.

关键词：斜拉桥基准模型鱼骨梁模型板壳单元模型健康监测改进遗传算法

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考虑易用性和可解释性的自组织映射-即时学习风险预测框架

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西安交通大学学报 2024年第5期58卷 212-220页

作者：马潇驰陆建霍宗鑫夏萧菡东南大学江苏省城市智能交通重点实验室南京211189 东南大学现代城市交通技术江苏高校协同创新中心南京211189 东南大学交通学院南京211189 南洋理工大学土木与环境工程学院新加坡639798

为提高风险预测系统的易用性和可解释性,提出基于自组织映射网络(SOM)改进的即时学习(JITL)风险预测框架。首先,应用SOM对数据样本进行聚类,并对聚类特征进行解释。进而,通过基于聚类结果的样本选择算法构建待测数据的相似样本集,在线... 详细信息

为提高风险预测系统的易用性和可解释性,提出基于自组织映射网络(SOM)改进的即时学习(JITL)风险预测框架。首先,应用SOM对数据样本进行聚类,并对聚类特征进行解释。进而,通过基于聚类结果的样本选择算法构建待测数据的相似样本集,在线上调用作为基学习器的支持向量机(SVM)进行建模并输出风险预测结果。最后,采用一个交通事故数据集对风险模型的性能进行测试,检验其精度、易用性和可解释性。结果表明:采用SOM-JITL策略的SVM模型,受试者工作状况曲线面积指标达到0.720,相比不使用该策略的传统SVM模型提高17.5%,精度较高;SOM-JITL模型构建所需参数调节工作少,具有较好的易用性;此外,SOM聚类结果准确识别出处于交通拥堵等高风险场景,与现实场景一致,具有可解释性。综上,SOM-JITL策略能有效提高基学习器的性能,达到精度、可解释性和易用性的平衡,有助于以低成本大规模推广风险预测系统。

关键词：机器学习风险预测易用性可解释性即时学习自组织映射

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Effects of oat β-glucan–based prebiotic blended formulas on defecation and gut microbiota in Chinese adults: a randomized clinical trial

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Food Science and Human Wellness 2024年

作者： Aiqi Li Lei Jin Hui xia Meiyuan Feng Xirui Zhou Yifang Chu Feng Liu Lanxing Jia Ximin Chen Dengfeng Xu Shanjie ma xiaofan Xu Xinyu Wang xiaoqing Li Guiju Sun Liegang Liu Key Laboratory of Environmental Medicine and Engineering of Ministry of Education， and Department of Nutrition and Food Hygiene， School of Public Health Southeast University Department of Nutrition and Food Hygiene， Hubei Key Laboratory of Food Nutrition and Safety， School of Public Health， Tongji Medical College， Huazhong University of Science and Technology Department of R&D Life Science，PepsiCo Inc Nutrition and Healthy Food Committee of Chinese Nutrition Society Health management Branch of Chinese Nutrition Society

Digestive health is important for overall well-being， but gut health problems are common in the Chinese population. The objective of this study was to investigate the effects of oat β-glucan–based prebiotic blended formulas in humans on digestive health by assessing defecation frequen-cy， defecation symptoms， stool quality， self-reported digestive feelings， defecation satisfaction， and gut bacteria. A parallel， randomized， double-blind， controlled trial was conducted in 168 eli-gible adults randomized to three groups for 14 days: Intervention Groups A and B received two different doses of oat β-glucan–based prebiotic blended formulas and a Control Group received oat β-glucan mixed with hydroxypropylmethyl-cellulose and microcrystalline cellulose. Partici-pants completed a defecation diary and Bristol stool chart daily and digestive system question-naires weekly. Fecal samples were collected on Day 0 and Day 14 to evaluate gut bacteria using 16S rDNA analysis. Both formulas improved defecation frequency， stool quality， defecation symptoms， defecation satisfaction， and on digestive health of human， compared with baseline (P mansia bacteria， compared to control， on Day 14. This study therefore demonstrated the beneficial effects of oat β-glucan–based prebiotic blended formulas on gut health in generally healthy Chinese adults. These formulas are a feasible nutritional strategy for digestive health.

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In Situ DIC Study on LCF Behavior of Retired Weld Joint Subjected to Prolonged Service at Elevated Temperature

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Acta Metallurgica Sinica(English Letters) 2022年第8期35卷 1317-1328页

作者： Anqi Zuo xia Liu Chendong shao Mingzhe Fan Ninshu ma Fenggui Lu Shanghai Key Laboratory of materials Laser Processing and Modification School of Materials Science and EngineeringShanghai Jiao Tong University Shanghai 200240China Shanghai Turbine Plant of Shanghai Electric Power Generation Equipment Co.Ltd.Shanghai 200240 China Joining and Welding Research Institute Osaka UniversityOsaka 567-0047.Japan

By using digital image correlation(DIC), low-cycle fatigue(LCF) behavior of CrMoV weld joint taken from a retired gas turbine rotor after 15-year service was investigated at 500 ℃ and 540 ℃. The most remarkable plastic strain was observed in the weld metal(WM), which was up to 6 times of the global strain at mid-life cycle. Due to the cyclic accumulation of local deformation, the stress–strain hysteresis loops relative to tensile or compressive strain concentration area in WM displayed the ratchetting shape. The local deformation accumulation of WM was attributed to the effect of the equiaxed grain zone near the WM center. The accumulated plastic strain was considered as the main fatigue failure mechanism.

关键词： Low-cycle fatigue Digital image correlation Local deformation Weld joint Failure mechanism

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Unlocking iron-based mixed-phosphate cathode for sodium-ion batteries through off-stoichiometry

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Nano Research 2024年第9期17卷 8119-8125页

作者： Zhaolu Liu Yongjie Cao Ning Wang Hui Yang Hao Zhang Xinyue Xu Nan Wang Jie Xu Yao Liu Junxi Zhang Yongyao xia Shanghai Key Laboratory of materials Protection and Advanced materials in Electric Power Shanghai University of Electric PowerShanghai 200090China Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative materials Fudan UniversityShanghai 200433China School of materials Science and Engineering Anhui University of TechnologyMa’anshan 243002China Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai 201800China

The off-stoichiometric iron-based phosphate(Na_(3.12)Fe_(2.44)(P_(2)O_(7))_(2),denoted as Na3.12)as a low cost and high structure stability cathode material has been widely studied for sodium-ion batteries(SIBs).However,the lower theoretical specific capacity(117 mah·g^(-1))has seriously limited its practical *** this work,we incorporate varying proportion of sodium-iron phosphate(NaFePO_(4))into the Na3.12 to form a series of new high specific capacity mixed-phosphates Na_(3.12+x)Fe_(2.44+x)(P_(2)O_(7))_(2)(PO_(4))x cathode materials for *** optimizing the introduction amount of NaFePO_(4)into Na_(3.12),the practical reversible of Na_(3.12+x)Fe_(2.44+x)(P_(2)O_(7))_(2)(PO_(4))_(x) increased from 92 to 125.2 mah·g^(-1).The nano-size Na5.12Fe4.44(P_(2)O_(7))_(2)(PO_(4))_(2) cathode material shows a reversible specific capacity of 125.2 mah·g^(-1)at 0.1 C in *** at 60 C,it still exhibits a reversible specific capacity of 93.3 mah·g^(-1)and keeps a capacity retention ratio of 87%after 3000 cycles at 20 ***,we present a novel approach to design a series of off-stoichiometric mixed-phosphates cathode materials for SIBs.

关键词： sodium-ion batteries cathode material iron-based mixed-phosphates off-stoichiometric

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Solid-state synthesis and ion transport characteristics of the β-KSbF_(4) for all-solid-state fluoride-ion batteries

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Journal of Energy Chemistry 2024年第7期94卷 758-767页

作者： Jiali Liu Huahui Zhao Jingcheng xia Lingguang Yi xiaoyi Chen Dongdu Li Shuhan Ni Xinyi Su Yixuan Chen Min Liu xianyou Wang National Base for International Science&Technology Cooperation National Local Joint Engineering Laboratory for Key Materials of New Energy Storage BatteryHunan Province Key Laboratory of Electrochemical Energy Storage&ConversionSchool of ChemistryXiangtan UniversityXiangtan 411105HunanChina College of New Energy Ningbo University of TechnologyNingbo 315336ZhejiangChina

All-solid-state fluoride ion batteries(FIBs)have been recently considered as a post-lithium-ion battery system due to their high safety and high energy *** like all solid-state lithium batteries,the key to the development of FIBs lies in room-temperature electrolytes with high ionic conductivity.β-KSbF_(4) is a kind of promising solid-state electrolyte for FIBs owing to its rational ionic conductivity and relatively wide electrochemical stability window at room ***,the previous synthesis routes ofβ-KSbF_(4) required the use of highly toxic hydrofluoric acid and the ionic conductivity of as-prepared product needs to be further ***,the β-KSbF_(4) sample with an ionic conductivity of 1.04×10^(-4)s cm^(-1)(30°C)is synthesized through the simple solid-state *** order to account for the high ionic conductivity of the as-synthesizedβ-KSbF_(4),X-ray diffraction(XRD),scanning electron microscopy(SEM),and energy dispersive X-ray spectroscopy(EDS)are used to characterize the physic-ochemical *** results show that the as-synthesizedβ-KSbF_(4) exhibits higher carrier concentra-tion of 1.0×10^(-6)S cm-Hz^(-1)K and hopping frequency of 1.31×10^(6)Hz at 30°C due to the formation of the fluorine ***,the hopping frequency shows the same trend as the changes of ionic conductivity with the changes of temperature,while the carrier concentration is found to be almost *** two different trends indicate the hopping frequency is mainly responsible for the ionic conduc-tion behavior withinβ-KSbF_(4).Furthermore,the all-solid-state FIBs,in which Ag and Pb+PbF_(2) are adopted as cathode and anode,andβ-KSbF_(4) as fluoride ion conductor,are capable of reversible charge and *** assembled FIBs show a discharge capacity of 108.4 ma h g^(-1) at 1st cycle and 74.2 ma h g^(-1) at 50th *** on an examination of the capacity decay mechanism,it has been found that deterioration of the electrolyte/electrode int

关键词： Solid-state electrolyte Carrier concentration Hopping frequency β-KSbF_(4) All-solid-state fluoride ion batteries

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