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Spotted Hyena Optimizer Driven Deep Learning-Based Drug-Drug Interaction Prediction in Big Data Environment

Computer Systems Science & Engineering 2023年第9期46卷 3831-3845页

作者： Mohammed Jasim Mohammed Jasim shakir fattah kak Zainab Salih Ageed Subhi R.M.Zeebaree Engineering College Al-Kitab UniversityKirkukIraq Information Technology Department Technical College of Informatics-AkreDuhok Polytechnic UniversityDuhokIraq Computer Science Department College of ScienceNawroz UniversityDuhokIraq Energy Engineering Department Technical College of EngineeringDuhok Polytechnic UniversityDuhokIraq

Nowadays,smart healthcare and biomedical research have marked a substantial growth rate in terms of their presence in the literature,computational approaches,and discoveries,owing to which a massive quantity of experimental datasets was published and generated(Big Data)for describing and validating such ***-drug interaction(DDI)significantly contributed to drug administration and *** continues as the main obstacle in offering inexpensive and safe *** normally happens for patients with extensive medication,leading them to take many drugs *** may cause side effects,either mild or severe health *** reduced victims’quality of life and increased hospital healthcare expenses by increasing their recovery *** efforts were made to formulate new methods for DDI prediction to overcome this *** this aspect,this study designs a new Spotted Hyena Optimizer Driven Deep Learning based Drug-Drug Interaction Prediction(SHODL-DDIP)model in a big data *** the presented SHODL-DDIP technique,the relativity and characteristics of the drugs can be identified from different sources for *** input data is preprocessed at the primary level to improve its ***,the salp swarm optimization algorithm(SSO)is used to select *** this study,the deep belief network(DBN)model is exploited to predict the DDI *** SHO algorithm is involved in improvising the DBN model’s predictive outcomes,showing the novelty of the *** experimental result analysis of the SHODL-DDIP technique is tested using drug databases,and the results signified the improvements of the SHODLDDIP technique over other recent models in terms of different performance measures.

关键词： Drug-drug interaction deep learning spotted hyena optimization feature selection classification

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