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Outcomes of Layered versus Mass Closure in Transverse Incision during Emergency Laparotomy in Children

Journal of Biosciences and Medicines 2020年第8期8卷 180-193页

作者： Khandoker Moynul Hasan shahnoor islam Md. Ashraf Ul Huq Muhammed Moinul Huque Shah Md. Rezaul Karim Mohammad Shafiul Azam Md. Iqbal Hossain Talukder Sharmin Ara Begum Mohammad Kamrul Ahsan A. K. M. Shahidur Rahman Department of Pediatric Surgery Dhaka Medical College Hospital (DMCH) Dhaka Bangladesh Department of Pediatric Urology Dhaka Medical College Hospital (DMCH) Dhaka Bangladesh Department of Surgery Sheikh Hasina Medical College Hospital Habiganj Bangladesh Department of Urology National Institute of Kidney Diseases and Urology (NIKDU) Dhaka Bangladesh Department of Surgery Sheikh Hasina Medical College Hospital Tangail Bangladesh Department of Anesthesiology National Institute of Traumatology and Orthopedic Rehabilitation (NITOR) Dhaka Bangladesh Holy Family Red Crescent Medical College Hospital (HFRCMCH) Dhaka Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh

Background: The value of laparotomy closure technique may be measured by the incidence of early and late wound complications. The best laparotomy closure technique should be less time consuming, easy and cost-effective, while preventing both early and late complications. Objective: To compare the outcomes of layered versus mass closure in transverse incision during emergency laparotomy in children. Methods: This prospective comparative study was conducted at Department of Pediatric Surgery, Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh from July 2016 to June 2018. A total of 60 pediatric age cases that underwent laparotomy were included in this study. Cases were randomly allocated into two groups;30 patients were in Group A (Layered closure) and 30 patients were in Group B (Mass closure). The outcome variables were time required for wound closure, wound infection, wound dehiscence and incisional hernia. Data were analyzed and compared by statistical tests. Results: The mean age of Group A and Group B patients were 31.08 ± 30.25 months and 34.70 ± 42.73 months respectively (p = 0.706). The ratio between male and female subject was 1.1:1 in Group A and 3.3:1 in Group B. The common diseases of the study patients who underwent laparotomy were intussusceptions, intestinal obstruction due to bands and adhesion, perforated appendix and perforation of small intestine due to blunt trauma respectively. Mean wound closure time was significantly less in mass closure group [28.20 ± 2.17 minutes in layered closure group and 18.80 ± 1.67 minutes in mass closure group, (p ≤ 0.001)]. Wound infection rate, incidence of superficial wound dehiscence, and incisional hernia were relatively less in mass closure group, however, the differences were not statistically significant (p = 0.053, p = 0.095 and p = 0.301 respectively). There was no complete wound dehiscence in Group A, but that was in 1 (3.3%) patient i

关键词： Laparotomy Layered Closure Mass Closure

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Comparative assessment of total polyphenols, antioxidant and antimicrobial activity of different tea varieties of Bangladesh

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Asian Pacific Journal of Tropical Biomedicine 2017年第4期7卷 352-357页

作者： Yead Morshed Nibir Ahmed Faisal Sumit Anwarul Azim Akhand Nazmul Ahsan Mohammad shahnoor Hossain Department of Genetic Engineering and Biotechnology University of DhakaDhaka 1000Bangladesh

Objective: To determine the total polyphenol content, antioxidant activity and antibacterial properties of the extracts of different Bangladeshi tea varieties such as flowery broken orange pekoe, broken orange pekoe, red dust and green ***: Total phenolic and flavonoid contents were determined by Folin–Ciocalteu and aluminum chloride colorimetric assay, *** antioxidant capacity was determined by ferric ion reducing antioxidant power and phosphomolybdenum *** activity was evaluated by disc diffusion method in agar plate and subsequently, the minimum inhibitory concentration was determined by broth dilution ***: Total phenolic and flavonoid contents were significantly higher(P < 0.05) in green tea compared to other three black tea *** green tea also showed a higher free radical scavenging and antioxidant activities than all the other tea varieties tested(P < 0.05).In addition, the extracts of all four tea varieties showed inhibitory activity against several pathogenic bacteria and also the same trend of higher antimicrobial activity of green tea than other tea varieties was ***: Taken together, the results of this study demonstrated that Bangladeshi tea,especially the green tea, may act as a substitute for natural antioxidants and as a promising antibacterial agent for beneficial influence in human health.

关键词： Tea extracts Antioxidant activity Antibacterial activity Total phenolic content

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