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Enhancing Mild Cognitive Impairment Detection through Efficient Magnetic Resonance Image Analysis

Computers, Materials & Continua 2024年第8期80卷 2081-2098页

作者： Atif Mehmood Zhonglong Zheng Rizwan Khan Ahmad Al Smadi Farah shahid shahid iqbal Mutasem K.Alsmadi Yazeed Yasin Ghadi Syed Aziz Shah Mostafa M.Ibrahim Department of Computer Science and Technology Zhejiang Normal UniversityJinhua321002China Zhejiang Institute of Photoelectronics&Zhejiang Institute for Advanced Light Source Zhejiang Normal UniversityJinhua321004China Department of Data Science and Artificial Intelligence Zarqa UniversityZarqa13100Jordan School of Chemical and Environmental Engineering College of ChemistryChemical Engineering andMaterials ScienceSoochow UniversitySuzhou215123China Department of Management Information Systems College of Applied Studies and Community ServiceImam Abdulrahman Bin Faisal UniversityDammam32244Saudi Arabia Department of Computer Science Al Ain UniversityAbu Dhabi999041United Arab Emirates Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61519Egypt Healthcare Technology and Innovation Theme Faculty Research Centre for Intelligent HealthcareCoventry UniversityCoventryCV48BWUK

Neuroimaging has emerged over the last few decades as a crucial tool in diagnosing Alzheimer’s disease(AD).Mild cognitive impairment(MCI)is a condition that falls between the spectrum of normal cognitive function and ***,previous studies have mainly used handcrafted features to classify MCI,AD,and normal control(NC)*** paper focuses on using gray matter(GM)scans obtained through magnetic resonance imaging(MRI)for the diagnosis of individuals with MCI,AD,and *** improve classification performance,we developed two transfer learning strategies with data augmentation(i.e.,shear range,rotation,zoom range,channel shift).The first approach is a deep Siamese network(DSN),and the second approach involves using a cross-domain strategy with customized *** performed experiments on the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset to evaluate the performance of our proposed *** experimental results demonstrate superior performance in classifying the three binary classification tasks:NC ***,NC ***,and MCI ***,we achieved a classification accuracy of 97.68%,94.25%,and 92.18%for the three cases,*** study proposes two transfer learning strategies with data augmentation to accurately diagnose MCI,AD,and normal control individuals using GM *** findings provide promising results for future research and clinical applications in the early detection and diagnosis of AD.

关键词： Alzheimer’s disease mild cognitive impairment normal control transfer learning classification augmentation

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Direct somatic embryogenesis and related gene expression networks in leaf explants of Hippeastrum ‘Bangkok Rose’

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Horticultural Plant Journal 2024年第2期10卷 556-572页

作者： Jingjue Zeng Yi Deng shahid iqbal Jiarui Zhang Kunlin Wu Guohua Ma Lin Li Guangyi Dai Rufang Deng Lin Fang Songjun Zeng Guangdong Provincial Key Laboratory of Applied Botany South China Botanical GardenChinese Academy of SciencesGuangzhouGuangdong 510650China University of the Chinese Academy of Sciences Beijing 100049China South China National Botanical Garden GuangzhouGuangdong 510650China Zhaoqing Branch Center of Guangdong Laboratory for Lingnan Modern Agricultural Science and Technology ZhaoqingGuangdong 526000China Horticultural Science Department North Florida Research and Education CenterUniversity of Florida/IFASQuincyFL 32351USA Public Laboratory of South China Botanical Garden Chinese Academy of SciencesGuangzhouGuangdong 510650China Key Laboratory of South China Agricultural Plant Molecular Analysis and Gene Improvement South China Botanical GardenChinese Academy of SciencesGuangzhouGuangdong 510650China

Hippeastrum, a highly diverse genus in the Amaryllidaceae family, is a valuable ornamental bulbous flowering plant. Somatic embryogenesis(SE) is an efficient method for mass production of Hippeastrum plantlets. Previous studies have been devoted to the in vitro propagation of Hippeastrum, but the SE and its regulatory networks are rarely reported. In this study, we established a direct SE method of Hippeastrum Bangkok Rose' using leaf bases as explants. MS supplemented with 1.00 mg·L^(-1)NAA +1.00 mg·L^(-1)KT + 0.25 mg·L^(-1)TDZ was the optimal medium for SE. Histological observations showed that the bipolar somatic embryo originated from the epidermal cell layer and underwent initiation,globular, scutellar and coleoptile stages. During SE, endogenous hormones of IAA, CTK, ABA, and SA were highly accumulated. Transcriptomic analysis revealed the genes encoding auxin biosynthesis/metabolic enzymes and efflux carriers were induced, while the auxin receptor of TIR1 and ARF transcriptional repressor of Aux/IAA were down-regulated and up-regulated, respectively, leading to suppression of auxin signaling. In contrast, cytokine signaling was promoted at the early stage of SE, as biosynthesis, transport, and signaling components were *** stress-related genes were up-regulated at the early or late stages of SE. Chromatin remodeling could also be dynamically regulated via distinct expression enzymes that control histone methylation and acetylation during SE. Moreover, key SE regulators, including WOXs and SERKs were highly expressed along with SE. Overall, the present study provides insights into the SE regulatory mechanisms of the Hippeastrum.

关键词： Hippeastrum Tissue culture Somatic embryogenesis Gene regulation

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Genetic dissection and origin of pleiotropic loci underlying multilevel fiber quality traits in upland cotton(Gossypium hirsutum L.)

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Journal of Integrative Agriculture 2024年第10期23卷 3250-3263页

作者： Hongge Li Shurong Tang Zhen Peng Guoyong Fu Yinhua Jia Shoujun Wei Baojun Chen Muhammad shahid iqbal Shoupu He Xiongming Du Zhengzhou Research Base State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/School of Agricultural SciencesZhengzhou UniversityZhengzhou 450001China State Key Laboratory of Cotton Bio-breeding and Integrated Utilization/Institute of Cotton Research Chinese Academy of Agricultural SciencesAnyang 455000China

Cotton fiber quality is a persistent concern that determines planting benefits and the quality of finished textile ***,the limitations of measurement instruments have hindered the accurate evaluation of some important fiber characteristics such as fiber maturity,fineness,and neps,which in turn has impeded the genetic improvement and industrial utilization of cotton ***,12 single fiber quality traits were measured using Advanced Fiber Information System(AFIS)equipment among 383 accessions of upland cotton(Gossypium hirsutum L.).In addition,eight conventional fiber quality traits were assessed by the High Volume Instrument(HVI)***-wide association study(GWAS),linkage disequilibrium(LD)block genotyping and functional identification were conducted sequentially to uncover the associated elite loci and candidate genes of fiber quality *** a result,the previously reported pleiotropic locus FL_D11 regulating fiber length-related traits was identified in this *** importantly,three novel pleiotropic loci(FM_A03,FF_A05,and FN_A07)regulating fiber maturity,fineness and neps,respectively,were detected based on AFIS *** highly promising candidate genes were screened out by integrating RNA-seq and qRT-PCR analyses,including the reported GhKRP6 for fiber length,the newly identified GhMAP8 for maturity and GhDFR for *** origin and evolutionary analysis of pleiotropic loci indicated that the selection pressure on FL_D11,FM_A03 and FF_A05 increased as the breeding period approached the present and the origins of FM_A03 and FF_A05 were traced back to cotton *** findings reveal the genetic basis underlying fiber quality and provide insight into the genetic improvement and textile utilization of fiber in ***.

关键词： upland cotton single fiber quality pleiotropic loci candidate genes locus origin

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Generalized Coherent States for Position-Dependent Effective Mass Systems

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Communications in Theoretical Physics 2016年第12期65卷 615-620页

作者： Naila Amir shahid iqbal School of Electrical Engineering and Computer Sciences National University of Sciences and Technology School of Natural Sciences National University of Sciences and Technology

A generalized scheme for the construction of coherent states in the context of position-dependent effective mass systems has been presented. This formalism is based on the ladder operators and associated algebra of the system which are obtained using the concepts of supersymmetric quantum mechanics and the property of shape invariance. In order to exemplify the general results and to analyze the properties of the coherent states, several examples have been considered.

关键词： generalized coherent states supersymmetric quantum mechanics shape invariance ladder operators position-dependent effective mass systems non-linear oscillators Mandel parameter subPoissonian statistics

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Barut–Girardello Coherent States for Nonlinear Oscillator with Position-Dependent Mass

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Communications in Theoretical Physics 2016年第7期65卷 41-48页

Using ladder operators for the non-linear oscillator with position-dependent effective mass, realization of the dynamic group SU(1,1) is presented. Keeping in view the algebraic structure of the non-linear oscillator, coherent states are constructed using Barut–Girardello formalism and their basic properties are discussed. Furthermore, the statistical properties of these states are investigated by means of Mandel parameter and second order correlation function. Moreover,it is shown that in the harmonic limit, all the results obtained for the non-linear oscillator with spatially varying mass reduce to corresponding results of the linear oscillator with constant mass.

关键词： position-dependent mass nonlinear oscillator Schdinger factorization Ladder operators su(1 1) algebra Barut–Girardello coherent states sub-poissonian statistics

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Coherent States of Nonlinear Oscillators with Position-Dependent Mass:Temporal Stability and Fractional Revivals

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Communications in Theoretical Physics 2017年第8期68卷 181-190页

作者： Naila Amir shahid iqbal School of Electrical Engineering and Computer Sciences National University of Sciences and Technology Department of Physics School of Natural Sciences National University of Sciences and Technology

We develop generalized coherent states for a class of nonlinear oscillators with position-dependent effective mass in the context of the Gazeau–Klauder formalism and discuss some of their properties. In order to investigate the temporal evolution we first explore the statistical properties by means of weighting distribution and the Mandel parameter. It is found that the temporal evolution of the coherent states may exhibit the phenomena of quantum revivals and fractional revivals for a particular choice of position-dependent mass oscillator.

关键词： position-dependent effective mass nonlinear oscillators Gazeau–Klauder coherent states Mandel parameter sub-Poissonian statistics temporal stability quantum revivals fractional revivals

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Exact Solutions of Schrdinger Equation for the Position-Dependent Effective Mass Harmonic Oscillator

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Communications in Theoretical Physics 2014年第12期61卷 790-794页

作者： Naila Amir shahid iqbal School of Natural Sciences National University of Sciences and Technology

A one-dimensional harmonic oscillator with position-dependent effective mass is studied. We quantize the oscillator to obtain a quantum Hamiltonian, which is manifestly Hermitian in configuration space, and the exact solutions to the corresponding Schr¨odinger equation are obtained analytically in terms of modified Hermite *** is shown that the obtained solutions reduce to those of simple harmonic oscillator as the position dependence of the mass vanishes.

关键词： nonlinear harmonic oscillator position-dependent effective mass system Schr¨odinger equation modified Hermite polynomials

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Velocity and Structural Modeling of Mesozoic Chiltan Limestone and Goru Formation for Hydrocarbon Evaluation in the Bitrisim Area, Lower Indus Basin, Pakistan

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Acta Geologica Sinica(English Edition) 2016年第1期90卷 258-275页

作者： Sarfraz KHAN Zahid LATIF Muhammad HANIF Irfan U. JAN shahid iqbal National Centre of Excellence in Geology(NCEG) University of PeshawarPakistan Earth Sciences Department Quaid-e-Azam University(QAU)IslamabadPakistan

The present study focuses on building a workflow for structural interpretation and velocity modeling and implementing to Jurassic-Cretaceous succession （Chiltan Limestone and Massive sand of the Lower Goru Formation）. 2D-Migrated seismic sections of the area are used as data set and in order to confirm the presence of hydrocarbons in the study area, P and S-wave seismic velocities are estimated from single-component seismic data. Some specific issues in the use of seismic data for modeling and hydrocarbon evaluation need to deal with including distinguishing the reservoir and cap rocks, and the effects of faults, folds and presence of hydrocarbons on these rocks. This study has carried out the structural interpretation and modeling of the seismic data for the identification of traps. The results demonstrate existence of appropriate structural traps in the form of horst and grabens in the area. 2D and 3D velocity modeling of the horizons indicates the presence of high velocity zones in the eastern half of the study while relatively low velocity zones are encountered in the western half of the area. Two wells were drilled in the study area （i.e. Fateh-01 and Ichhri-01） and both are dry. Immature hydrocarbons migration is considered as a failure reason for Fateh-01 and Ichhri-01 well.

关键词： 2D and 3D Time-Depth models velocity modeling structural modeling Chiltan limestone Goru Formation

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Household behavior in practicing mental budgeting based on the theory of planned behavior

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Financial Innovation 2018年第1期4卷 408-421页

作者： Ume Habibah Ibne Hassan Muhammad shahid iqbal Naintara Department of Management Sciences Air University Multan CampusMultanPakistan Department of Commerce Bahauddin Zakariya UniversityMultanPakistan. Bahauddin Zakariya University MultanPakistan.

Ajzen’s theory of planned behavior(TPB)suggests that planned behavior is determined by behavioral *** extensive literature based on TPB,household mental budgeting behavior explained by TPB is *** current study empirically tested TPB factors in light of mental budgeting *** hypothesized model was tested using partial least squares structural equation modeling(PLS-SEM).PLS-SEM was employed using a Likert-scaled questionnaire administered to 275 *** results indicate that mental budgeting attitude and mental budgeting past behavior strongly predict mental budgeting intention,and mental budgeting intention predicts mental budgeting ***,mental budgeting intention partially mediates the relationship between mental budgeting attitude and mental budgeting behavior,and mental budgeting past behavior and mental budgeting *** study contributes to the academic interest in theoretical progress in household behavior.

关键词： Mental budgeting behavior Household budgeting behavior Mental budgeting attitude Mental budgeting past behavior Mental budgeting intention

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Effectiveness of enforcement levels of speed limit and drink driving laws and associated factors -Exploratory empirical analysis using a bivariate ordered probit model

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Journal of Traffic and Transportation Engineering(English Edition) 2017年第3期4卷 272-279页

作者： Behram Wali Anwaar Ahmed shahid iqbal Arshad Hussain National Institute of Transportation School of Civil and Environmental Engineering National University of Sciencesand Technology Islamabad 44000 Pakistan Department of Civil and Environmental Engineering The University of Tennessee Knoxville TN 37996 USA Military College of Engineering National University of Sciences and Technology Risalpur 24080 Pakistan

The contemporary traffic safety research comprises little information on quantifying the simultaneous association between drink driving and speeding among fatally injured drivers. Potential correlation between driver＇s drink driving and speeding behavior poses a substantial methodological concern which needs investigation. This study therefore focused on investigating the simultaneous impact of socioeconomic factors, fatalities, vehicle ownership, health services and highway agency road safety policies on enforce- ment levels of speed limit and drink driving laws. The effectiveness of enforcement levels of speed limit and drink driving laws has been investigated through development of bivariate ordered probit model using data extricated from WHO＇s global status report on road safety in 2013. The consistent and intuitive parameter estimates along with statisti- cally significant correlation between response outcomes validates the statistical suprem- acy of bivariate ordered probit model. The results revealed that fatalities per thousand registered vehicles, hospital beds per hundred thousand population and road safety pol- icies are associated with a likely medium or high effectiveness of enforcement levels of speed limit and drink driving laws, respectively. Also, the model encapsulates the effect of several other agency related variables and socio-economic status on the response outcomes. Marginal effects are reported for analyzing the impact of such factors on in- terrnediate categories of response outcomes. The results of this study are expected to provide necessary insights to elemental enforcement programs. Also, marginal effects of explanatory variables may provide useful directions for formulating effective policy countermeasures for overcoming driver＇s speeding and drink driving behavior.

关键词： Speed limit law Drink driving law Enforcement Road traffic crashes

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