检索结果-南通市图书馆

Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue lymphoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第11期20卷 2751-2759页

作者： Jeong Bae Park ja Seol KooJeong Department of Internal Medicine College of MedicineDongguk UniversityGyeongju 780-350South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineKorea University Ansan HospitalAnsan 425-707South Korea

Gastrointestinal lymphoma is the most common type of extranodal lymphoma,and most commonly affects the *** zone B-cell lymphoma of the mucosa-associated lymphoid tissue(MALT)and diffuse large B-cell lymphoma are the most common histologic types of gastric *** its increasing incidence,diagnosis of gastric lymphoma is difficult at an earlier stage due to its nonspecific symptoms and endoscopic findings,and,thus,a high index of suspicion,and multiple,deep,repeated biopsies at abnormally and normally appearing sites in the stomach are *** addition,testing for Helicobacter pylori(***)infection and endoscopic ultrasonography to determine the depth of tumor invasion and involvement of regional lymph nodes is essential for predicting response to *** eradication and for assessment of disease *** addition,*** infection and MALT lymphoma development are associated,and complete regression of low-grade MALT lymphomas after *** eradication has been *** and/or chemotherapy can be used in cases that show poor response to *** eradication,negativity for *** infection,or high-grade lymphoma.

关键词： Mucosa-associated lymphoid tissue Lymphoma Helicobacter pylori Eradication Remission

Insulinotrophic and hypolipidemic effects of Ecklonia cava in streptozotocin-induced diabetic mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2012年第5期5卷 374-379页

作者： Mi-ja Kim Hye Kyung Kim Department of Food and Biotechnology Hanseo UniversitySeosan 356-706Republic of Korea Department of Pharmacology school of MedicineKyunghee UniversitySeoul 130-701Republic of Korea

Objective:To explore the anti-diabetic activity of Ecklonia cava(EC) in streptozotocin(STZ)-induced diabetic ***:Diabetes was induced by a single intraperitoneal injection of STZ(90 mg/kg).Normal and diabetic mice were treated with 0%,3%,and 5%EC diet for 4 weeks. Serum glucose and insulin concentrations,serum lipid profile,oral glucose tolerance test,and liver and pancreaticβ-cell histopathological observations were *** addition,in vitro glucose-induced insulin secretion was determined using pancreaticβ-islet ***:EC supplementation significantly and dose-dependently decreased serum glucose concentration, and improved glucose homeostasis in diabetic mice by preventing loss ofβ-cell mass resulting in increase of insulin *** triglyceride and total cholesterol concentrations in the serum and liver were markedly reduced by EC treatment in STZ-diabetic ***,LDL-,and HDL-cholesterol levels were ameliorated in EC supplemented diabetic *** steatosis induced by STZ was ameliorated by EC ***,in vitro insulinotrophic effect of EC extract was observed in pancreaticβ-***:This study demonstrated that EC is a potent and efficacious hypoglycemic and hypolipidemic agent,and prevents the loss ofβ-cell mass resulting in increase of insulin secretary capacity.

关键词： Diabetes Streptozotocin Insulin Lipid profile Pancreaticβ-cell

CONJUGATE FLOWS OVER A STEP IN A THREE-LAYER FLUID

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2002年第4期14卷 15-23页

作者： Wei, Gang Le, ja-Chun Dai, Shi-Qiang Inst. of Appl. Math. and Mech. Shanghai Univ. Shanghai 200072 China Sch. of Sci. P.L.A Univ. of Sci. and Eng. Nanjing 211101 China

The conjugate flows over a step with the height h_0, which might be positive or negative, was studied in a three-layer fluid and the coupled nonlinear equations were derived, with which the effects of varying height h_0 on the existence and evolution of conjugate flows were examined. It is concluded that the conjugate flow is sharply sensitive to the thickness of fluid layers and its characteristics alters remarkably due to the existence of the step. As the flow climbs up a step (h_0>0), the conjugate flow with a convex lower interface and a concave upper interface is allowed to appear, while the flow with the concave lower interface or the simultaneous concave interfaces will be depressed. As the flow goes down a step (i.e., h_0<0), on most occasions only one kind of conjugate flow could exist, which prossesses the form with the simultaneous convex interfaces and will disappear rapidly with the increase of the step depth.

关键词： conjugate flow flat solitary wave stratified flow step topography three-layer fluid

Crowdsourcing geographic information for disaster response:a research frontier

在线全文

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2010年第3期3卷 231-241页

作者： Michael F.Goodchild ja.lan Glennon Center for Spatial Studies University of CaliforniaSanta BarbaraCA 93106-4060USA

Geographic data and tools are essential in all aspects of emergency management:preparedness,response,recovery,and *** information created by amateur citizens,often known as volunteered geographic information,has recently provided an interesting alternative to traditional authoritative information from mapping agencies and corporations,and several recent papers have provided the beginnings of a literature on the more fundamental issues raised by this new *** quality is a major concern,since volunteered information is asserted and carries none of the assurances that lead to trust in officially created *** emergencies time is the essence,and the risks associated with volunteered information are often outweighed by the benefits of its *** example is discussed using the four wildfires that impacted the Santa Barbara area in 20072009,and lessons are drawn.

关键词： emergency management volunteered geographic information crowdsourcing Web 2.0 neogeography wildfire Santa Barbara

Nonlinear Local Lyapunov Exponent and Quantification of Local Predictability

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2008年第5期25卷 1919-1922页

作者：丁瑞强李建平 HA Kyung-ja State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG) Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 Division of Earth Environmental ~System Pusan National University Busan 609- 735 Korea

Nonlinear local Lyapunov exponent （NLLE） is applied to quantitatively determine the local predictability limit of chaotic systems. As an example, we find that the local predictability limit of Henon attractor varies considerably with time, and some underlying phase-spatial structure does not appear. The local predictability limit of initially adjacent points in phase space may be completely different. This will cause difficulties in making the long-time analogue forecast.

关键词： ATMOSPHERIC PREDICTABILITY

EFFECT OF LOADING TYPE ON FATIGUE CRACK GROWTH BEHAVIOR OF SOLDER JOINT IN ELECTRONIC PACKAGING

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2014年第3期27卷 245-258页

作者： Xishu Wang Huaihui Ren Bisheng Wu Su ja Norio Kawagoishi Department of Engineering Mechanics AML Tsinghua University China Longyuan Power Group Corporation Limited China Goudian CSIRO Earth Science and Resource Engineering Clayton VIC 3168 Australia Department of Mechanical System Engineering Daiichi Institute of TechnologyKagoshima 899-4395 Japan

Fatigue cracking tests of a solder joint were carried out using in-situ scanning electron microscopy （SEM） technology under tensile and bending cyclic loadings. The method for predicting the fatigue life is provided based on the fatigue crack growth rate of the solder joint. The results show that the effect of the loading type on the fatigue crack growth behavior of a solder joint cannot be ignored. In addition, the finite element analysis results help quantitatively estimate the response relationship between solder joint structures. The fatigue crack initiation life of a solder joint is in good agreement with the fatigue life （N50%） of a totally electronic board with 36 solder joints.

关键词： microcracking fatigue MEMS experimental techniques finite element method

nhibitory Role of Pentraxin-3 in Esophageal Squamous Cell Carcinoma

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第18期 2233-2240页

作者： Dan ja Department of Gastroenterology Beijing Friendship Hospital Capital Medical University Beijing 100050 China National Clinical Research Center for Digestive Diseases Beijing 100050 China Beijing Digestive Disease Center Beijing 100050 China Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases Beijing 100050 China

Background： Esophageal cancer is the sixth leading cause of cancer-related death worldwide. Pentraxin-3 （PTX3） is a member of the PTX superfamily. Here, we investigated the role of PTX3 in esophageal squamous cell carcinoma （ESCC）. Methods： The effect of PTX3 on ESCC cell proliferation, colony formation, apoptosis, migration, and invasion was investigated using cell viability assays, colony formation assays, flow cytometry, and migration and invasion assays. The effect of PTX3 on the tumorigenicity of ESCC in vivo was investigated with xenograft studies in nude mice. Results： PTX3 overexpression in ESCC cells reduced cellular proliferation and colony formation （P 〈 0.05） and increased the rate of apoptosis （P 〈 0.05）. PTX3 expression had no significant effect on the migratory or invasive potential of ESCC cells. In our mouse model of human ESCC, we achieved 100% successful tumor establishment. Compared with the control and empty vector-expressing groups, the PTX3-expressing group formed significantly smaller tumors （P 〈 0.05）. Conclusions： This study indicates that PTX3 might play an inhibitory role in ESCC.

关键词： Apoptosis Esophageal Squamous Cell Carcinoma Pentraxin-3 Proliferation

探究早期帕金森病Thy 1-SNCA模型小鼠运动学习障碍的时间特征

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

首都医科大学学报 2024年第5期45卷 881-890页

作者：付文欣王铁杨汝宁曲明芹高歌杨慧贾军首都医科大学基础医学院生理学与病理生理学学系北京100069 首都医科大学基础医学院神经生物学学系北京100069

目的本实验通过建立早期帕金森病(Parkinson s disease,PD)小鼠模型,以探究PD模型出现运动学习障碍的时间特征。方法选用6月龄Thy 1-SNC A转基因(transgenic,TG)小鼠作为早期PD模型,与同龄野生型(wild type,WT)小鼠进行对比分析。通过... 详细信息

目的本实验通过建立早期帕金森病(Parkinson s disease,PD)小鼠模型,以探究PD模型出现运动学习障碍的时间特征。方法选用6月龄Thy 1-SNC A转基因(transgenic,TG)小鼠作为早期PD模型,与同龄野生型(wild type,WT)小鼠进行对比分析。通过旷场实验、爬杆实验和Y迷宫等行为学手段来评估小鼠的运动功能和空间工作记忆能力,并以经典的匀加速转棒实验作为运动学习的行为学范式,来评估其运动学习能力。结果6月龄的Thy 1-SNC A TG小鼠在运动功能和空间记忆能力方面并未显示出异常,却呈现出明显的运动学习障碍。结论在早期PD模型小鼠上存在着特定的运动学习障碍,可作为早期PD的一个重要诊断指标;同时匀加速转棒测试可作为检测PD运动学习障碍的一种重要的行为学手段。

关键词：帕金森病早期帕金森病模型运动学习障碍运动症状

Chronic prostatitis in Korea:a nationwide postal survey of practicing urologists in 2004

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2005年第4期7卷 427-432,页

作者： ja-Hyeon Ku jae-Seung Paick Soo-Woong Kim Department of Urology Seoul National University College of MedicineSeoul 110-744Korea

Aim： To examine the diagnosis and treatment of chronic prostatitis by means of a nationwide postal survey of practicing urologists in 2004. Methods： A random sample of 850 Korean urologists from the Korean Urological Association Registry of Physicians were asked to complete a questionnaire that explored practicing characteristics, attitudes and diagnostic and treatment strategies in the management of chronic prostatitis. Results： Of the 850 questionnaires sent, 302 were returned （response rate 35.5 %） and 275 were induced in the final analysis. More than 50 % believed in a multifactorial etiology for chronic prostatitis and 52 % considered chronic abacterial prostatitis to be bacterial in nature. For routine diagnostic assessment, the most commonly used tests were reported to be urinalysis （95.3 %）, analysis of expressed prostatic secretions （89.5 %） and digital rectal examination （81.1%）. Only a few urologists use specific lower urinary tract cultures. Symptom assessment according to the National Institute of Health-Chronic Prostatitis Symptom Index was less frequently used （12.7 %）. First choices for therapy included antibiotics （96.4 %）, alpha-blockers （71.6 %） and sitz baths （70.5 %）. If unsuccessful, urologists frequently continued to prescribe a second course of either alpha-blockers （69.5 %） or antibiotics （57.8 %）. Conclusion： These data provide a picture of current practice regarding the management of chronic prostatitis in Korea. The diagnostic and treatment practices for prostatitis do not follow standard textbook algorithms. Further studies are needed to elucidate the etiology and pathogenesis of chronic prostatitis and to establish guidelines for its diagnosis and treatment.

关键词： prostatitis chronic pelvic pain syndrome questionnaire diagnosis treatment