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Neural Regeneration Research 2025年第6期20卷 1699-1700页

作者： seyed mojtaba hosseini Soheila Karimi-Abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada Manitoba Multiple Sclerosis Research Center WinnipegMBCanada Children Hospital Research Institute of Manitoba WinnipegMBCanada

Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord undergoes a cascade of secondary injury mechanisms that are driven by disruption of the blood-spinal cord ba rrier,vascula r inju ry,glial reactivity,neu roinfla mmation,oxidative stress,lipid peroxidation,and glutamate excitotoxicity that culminate in neuronal and oligodendroglial cell death,demyelination,and axonal damage(Alizadeh et al.,2019).To achieve a meaningful functional recovery after SCI,regeneration of new neurons and oligodendrocytes and their successful growth and integration within the neural network are critical steps for reconstructing the damaged spinal cord tissue (Fischer et al.,2020).

关键词： peroxidation Fischer injury

Solar and wind energy potential assessment for Razavi Khorasan Province in Iran

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Journal of Central South University 2024年第6期31卷 2027-2038页

作者： hosseini Amirpouya RAMEZANI Faeze MIRhosseini mojtaba School of Advanced Technologies Iran University of Science and TechnologyTehranIran

This study aims to evaluate the solar and wind energy potential across Razavi Khorasan Province,Iran,with a specific focus on the Khaf region.A preliminary assessment of mean solar radiation,mean wind speeds,and Weibull distribution parameters was conducted for different towns and zones within the *** findings showed that Khaf has favorable characteristics for further *** solar and wind energy metrics examined include global horizontal irradiance,clearness index,wind rose patterns,and turbulence *** a height of 40 m,Khaf’s wind power density reached 1650 W/m^(2),indicating exceptional wind energy generation ***,Khaf received an average annual solar radiation of 2046 kW·h/m^(2),representing significant solar energy *** these substantial renewable resources in Khaf could allow Razavi Khorasan Province to reduce reliance on fossil fuels,improve energy sustainability,and mitigate climate change *** research contributes an in-depth assessment of Razavi Khorasan's solar and wind energy potential,particularly for the promising Khaf *** work may examine optimal sites for renewable energy projects and grid integration strategies to leverage these resources.

关键词： solar energy wind energy Razavi Khorasan radiation Weibull distribution

Matching user identities across social networks with limited profile data

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Frontiers of Computer Science 2020年第6期14卷 171-184页

作者： Ildar NURGALIEV Qiang QU seyed mojtaba hosseini BAMAKAN Muhammad MUZAMMAL Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518055China Sberbank Moscow 121170Russia Department of Management Yazd UniversityYazd 89195-741Iran Department of Computer Science Bahria UniversityIslamabad 44000Pakistan

Privacy preservation is a primary concern in social networks which employ a variety of privacy preservations mechanisms to preserve and protect sensitive user information including age,location,education,interests,and *** task of matching user identities across different social networks is considered a challenging *** this work,we propose an algorithm to reveal user identities as a set of linked accounts from different social networks using limited user profile data,i.e,user-name and ***,we propose a framework,ExpandUIL,that includes three standalone al-gorithms based on(i)the percolation graph matching in Ex-pand FullName algorithm,(i)a supervised machine learning algorithm that works with the graph embedding,and(ii)a combination of the two,ExpandUserLinkage *** proposed framework as a set of algorithms is significant as,(i)it is based on the network topology and requires only name feature of the nodes,(i)it requires a considerably low initial seed,as low as one initial seed suffices,(ii)it is iterative and scalable with applicability to online incoming stream graphs,and(iv)it has an experimental proof of stability over a real ground-truth *** on real datasets,Instagram and VK social networks,show upto 75%recall for linked ac-counts with 96%accuracy using only one given seed pair.

关键词： social networks user identity linkage graph structure learning,maximum subgraph matching graph percolation

Multidisciplinary design optimization of a dual-spin guided vehicle

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Defence Technology（防务技术） 2024年第7期37卷 133-148页

作者： Jalal Karimi Mohammad Reza Rajabi seyed Hossein Sadati seyed Mahid hosseini Department of Aerospace Engineering Malek Ashtar University of TechnologyTehranIran

In this research,a Multidisciplinary Design Optimization approach is proposed for the dual-spin guided flying projectile design considering external and internal parts of the body as design *** this way,a parametric formulation is *** related disciplines,including structure,aerodynamics,guidance,and control are *** total mass,maximum aerodynamic control effectiveness,minimum miss distance,maximum yield stress in all subsystems,controllability and gyroscopic stability constraints are some of objectives/constraints taken into *** problem is formulated in All-At-Ones Multidisciplinary Design Optimization approach structure and solved by Simulated Annealing and minimax *** optimal configurations are evaluated in various *** resulted optimal configurations have met all design objectives and constraints.

关键词： Flying projectile optimal design All-at-ones multidisciplinary optimization Structure discipline Guidance and control discipline Aerodynamic discipline

12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation

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Neural Regeneration Research 2015年第6期10卷 904-908页

作者： seyed mojtaba hosseini Mohammad Farahmandnia Zahra Razi Somayeh Delavarifar Benafsheh Shakibajahromi Student Research Committee Shiraz University of Medical Sciences Cell and Molecular Medicine Student Research Group Medical SchoolShiraz University of Medical Sciences Stem Cell Laboratory Department of AnatomyShiraz University of Medical Sciences

Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route. Rat models of cerebral ischemia were established by occlusion of the middle cerebral artery. At 1, 12 hours, 1, 3, 5 and 7 days after cerebral ischemia, bone marrow mesenchymal stem cells were injected via the tail vein. At 28 days after cerebral ischemia, rat neurological function was evaluated using a 6-point grading scale and the pathological change of ischemic cerebral tissue was observed by hematoxylin-eosin staining. Under the fluorescence microscope, the migration of bone marrow mesenchymal stem cells was examined by PKH labeling. Caspase-3 activity was measured using spectrophotometry. The optimal neurological function recovery, lowest degree of ischemic cerebral damage, greatest number of bone marrow mesenchymal stem cells migrating to peri-ischemic area, and lowest caspase-3 activity in the ischemic cerebral tissue were observed in rats that underwent bone marrow mesenchymal stem cell transplantation at 12 hours after cerebral ischemia. These findings suggest that 12 hours after cerebral ischemia is the optimal time for tail vein injection of bone marrow mesenchymal stem cell transplantation against cerebral ischemia, and the strongest neuroprotective effect of this cell therapy appears at this time.

关键词： nerve regeneration bone marrow mesenchymal stem cells cerebral ischemia tail veininjection middle cerebral artery occlusion cell therapy neuroprotection

Blockchain technology forecasting by patent analytics and text mining

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Blockchain(Research and Applications) 2021年第2期2卷 97-110页

作者： seyed mojtaba hosseini Bamakan Alireza Babaei Bondarti Parinaz Babaei Bondarti Qiang Qu Department of Industrial Management Yazd UniversityYazd89195-741Iran Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen518055China Department of Library and Information Science Kharazmi UniversityTehran15719-14911Iran

Information technologies(ITs)have been playing an important role in improving our society,and the fast evolution of ITs creates a competitive environment not only for companies but also for ***,recognizing the future trend of technologies can be effective in decision-making with regard to technology selection and *** technology with its vast and impressive applications has received considerable attention from researchers,investors,and public *** purpose of this research is to investigate blockchain technology to explore its trends according to their classification by use of the World Intellectual Property Organization(WIPO)***,we particularly evaluate the registered patents in the world's most well-known patent databases such as the USA patent *** drew the current technology trends in blockchain patents by applying the text mining and clustering *** results represent that the registered patents in the USA patent database have been achieved in the growth *** means,attention to the blockchain is rising nowadays and most patents focused the cryptocurrencies and their applications in ***,blockchain technology is in the emergence phase and is evolving by researchers and inventors.

关键词： Technology forecasting Blockchain technology Patent analysis Text mining Technology life cycle

Theoretical framework of the Isfahani style: Inspiring sustainable aspects of a vernacular urban development

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Frontiers of Architectural Research 2024年第2期13卷 349-369页

作者： Hatef Jafari Sharami seyed Jamalaldin hosseini Department of Architecture and Urbanism University of EyvanekeyEyvanekey 99888-35918Iran Faculty of Civil and Architecture University of EyvanekeyEyvanekey 99888-35918Iran

The Isfahani style represents a method of traditional Iranian architecture and urban development that existed in the early 20th century and is regarded as a leading model in most traditional Iranian cities. It exhibits several vigorous features contributing to its recognition as a traditional approach to sustainable architecture and urban development. This research endeavors to reveal a theoretical framework beneath these inspiring aspects using the typology of sustainable modern forms, including the hierarchy, passive design strategies, compactness, density, diversity, mixed land use, pluralism, balance, good composition, and integration over time. To this end, the study employs qualitative research methods, drawing from traditional samples, to identify innovative, energy and socially efficient, and low-impact strategies implemented in this vernacular architecture of Iran's semi-arid and hot climates. The findings revealed that the neighborhood concept as a local and plural community (Mahalla) was a vital phenomenon in Iran's urban development. Apparently, the demise of this paradigm effectively played an important role in the numerous challenges regarding the social, energy, and economic viability of modern Iranian cities. Hence, this study presented theoretical frameworks—aligned with sustainable concepts—from the Isfahani style through its analysis, classification, and interpretation, which can contribute to modern urban development.

关键词： Isfahani style Vernacular urban development Sustainable urban development Iranian cities Vernacular architecture

Circulating levels of advanced glycation end products in females with polycystic ovary syndrome:a meta-analysis

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Reproductive and Developmental Medicine 2024年第2期8卷 93-100页

作者： seyed Sobhan Bahreiny Akram Ahangarpour mojtaba Aghaei Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Medical Basic Sciences Research Institute Physiology Research CenterDepartment of PhysiologySchool of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran

Polycystic ovary syndrome(PCOS)is a common endocrine disorder characterized by a hormonal imbalance that affects females of reproductive *** association between advanced glycation end products(AGEs)and PCOS has attracted considerable attention in recent years,highlighting the potential of AGEs as biomarkers for this *** the present systematic review and meta-analysis,we aimed to examine the association between AGEs and PCOS,evaluate their potential as biomarkers,and improve our understanding of the pathophysiology of PCOS and its associated metabolic complications.A literature search was performed using various databases from January 2000 to March 2023 to identify relevant studies investigating the association between AGEs and *** effect estimates were calculated using standardized mean differences(SMD)with 95%confidence intervals(CIs).Sub-group and meta-regression analyses were performed to examine potential sources of *** meta-analysis included six studies with a total of 623 *** results revealed a significant increase in circulating AGE levels in females with PCOS compared to healthy females(SMD=2.35;95%CI:1.10-3.60;P<0.001).Significant heterogeneity was observed between the studies(I2=96.37%;P<0.001),indicating the presence of several factors influencing the ***-group analyses based on body mass index,age,and homeostatic model assessment for insulin resistance indicated differential effects of AGEs on specific *** systematic review and meta-analysis support the association between elevated AGE levels and PCOS,thereby suggesting the potential role of AGEs as biomarkers in PCOS.

关键词： Polycystic ovary syndrome PCOS Advanced glycation end products AGEs Biomarker Meta-analysis

Differentiation of Wharton's jelly mesenchymal stem cells into neurons in alginate scaffold

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Neural Regeneration Research 2015年第8期10卷 1312-1316页

作者： seyed mojtaba hosseini Attiyeh Vasaghi Newsha Nakhlparvar Reza Roshanravan Tahereh Talaei-khozani Zahra Razi Student Research Committee Shiraz University of Medical Sciences Cell and Molecular Medicine Student Research Group Medical School Shiraz University of Medical Sciences Stem Cell Laboratory Department of Anatomy Shiraz University of Medical Sciences Colorectal Research Center Department of Surgery Shiraz University of Medical Science Tissue Engineering Laboratory Department of Tissue Engineering School of Advanced Medical Science and Technology Shiraz University of Medical Sciences Laboratory for Stem Cell Research Department of Anatomy Medical School Shiraz University of Medical Sciences Department of Medical Physics Shiraz University of Medical Sciences

Alginate scaffold has been considered as an appropriate biomaterial for promoting the differentiation of embryonic stem cells toward neuronal cell lineage. We hypothesized that alginate scaffold is suitable for culturing Wharton’s jelly mesenchymal stem cells（WJMSCs） and can promote the differentiation of WJMSCs into neuron-like cells. In this study, we cultured WJMSCs in a three-dimensional scaffold fabricated by 0.25% alginate and 50 m M Ca Cl2 in the presence of neurogenic medium containing 10 μM retinoic acid and 20 ng/m L basic fibroblast growth factor. These cells were also cultured in conventional two-dimensional culture condition in the presence of neurogenic medium as controls. After 10 days, immunofluorescence staining was performed for detecting β-tubulin（marker for WJMSCs-differentiated neuron） and CD271（motor neuron marker）. β-Tubulin and CD271 expression levels were significantly greater in the WJMSCs cultured in the three-dimensional alginate scaffold than in the conventional two-dimensional culture condition. These findings suggest that three-dimensional alginate scaffold cell culture system can induce neuronal differentiation of WJMSCs effectively.

关键词： nerve regeneration Wharton’s jelly mesenchymal stem cells mesenchymal stem cells neurons motor neurons alginate 3D scaffold neural regeneration

Nicorandil potentiates sodium butyrate induced preconditioning of neurons and enhances their survival upon subsequent treatment with H_(2)O_(2)

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Translational Neurodegeneration 2017年第1期6卷 291-299页

作者： Parisa Tabeshmehr Haider Kh Husnain Mahin Salmannejad Mahsa Sani seyed mojtaba hosseini Mohammad Hossein Khorraminejad Shirazi Student Research Committee Shiraz University of Medical SciencesShirazIran Cell&Molecular Medicine Student Research Group Medical FacultyShiraz University of Medical SciencesShirazIran Department of Basic Sciences SRURiyadhSaudi Arabia Stem Cell Laboratory Department of AnatomyShiraz University of Medical SciencesShirazIran

Background:Extensive loss of donor neural stem cell(NSCs)due to ischemic stress and low rate of differentiation at the site of cell graft are two of the major issues that hamper optimal outcome in NSCs transplantation *** that histone deacetylases(HDACs)modulate various cellular processes by deacetylating histones and non-histone proteins,we hypothesized that combined treatment with small molecules,sodium butyrate(NaB;a known HDAC inhibitor)and nicorandil,will enhance the rate neuronal differentiation of NSCs besides their preconditioning to resist oxidative ***:NSCs derived from 14-day old Sprague Dawley rat ganglion eminence were characterized for tri-lineage *** with 1 mM NaB significantly changed their culture characteristics while continuous treatment for 10 days enhanced their neural *** treatment also preconditioned the cells for their resistance to oxidative ***:The highest rate of neural differentiation and preconditioning effect was achieved when the NSCs were treated concomitantly with NaB and *** proliferation assay showed that concomitant treatment with NaB and nicorandil retarded their rate of ***:These data conclude that preconditioning of NSCs with NaB and nicorandil effectively enhances their differentiation capacity besides preconditioning the cells to support their survival under ischemic conditions.

关键词： Apoptosis Neural stem cells Oxidative stress Preconditioning