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New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1699-1700页

作者： seyed Mojtaba Hosseini Soheila Karimi-abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada Manitoba Multiple Sclerosis Research Center WinnipegMBCanada Children Hospital Research Institute of Manitoba WinnipegMBCanada

Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord undergoes a cascade of secondary injury mechanisms that are driven by disruption of the blood-spinal cord ba rrier,vascula r inju ry,glial reactivity,neu roinfla mmation,oxidative stress,lipid peroxidation,and glutamate excitotoxicity that culminate in neuronal and oligodendroglial cell death,demyelination,and axonal damage(Alizadeh et al.,2019).To achieve a meaningful functional recovery after SCI,regeneration of new neurons and oligodendrocytes and their successful growth and integration within the neural network are critical steps for reconstructing the damaged spinal cord tissue (Fischer et al.,2020).

关键词： peroxidation Fischer injury

Cognitive Power Management in Wireless Sensor Networks

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Journal of Computer Science & Technology 2015年第6期30卷 1306-1317页

作者： seyed Mehdi tabatabaei Vesal Hakami Mehdi Dehghan Department of Computer Engineering and Information Technology Amirkabir University of Technology Tehran 16846-13114 Iran

Dynamic power management （DPM） in wireless sensor nodes is a well-known technique for reducing idle energy consumption. DPM controls a node＇s operating mode by dynamically toggling the on/off status of its units based on predictions of event occurrences. However, since each mode change induces some overhead in its own right, guaranteeing DPM＇s eificiency is no mean feat in environments exhibiting non-determinism and uncertainty with unknown statistics. Our solution suite in this paper, collectively referred to as cognitive power management （CPM）, is a principled attempt toward enabling DPM in statistically unknown settings and gives two different analytical guarantees. Our first design is based on learning automata and guarantees better-than-pure-chance DPM in the face of non-stationary event processes. Our second solution caters tor an even more general setting in which event occurrences may take on an adversarial character. In this case, we formulate the interaction of an individual mote with its environment in terms of a repeated zero-sum game in which the node relies on a no-external-regret procedure to learn its mini-max strategies in an online fashion. We conduct numerical experiments to measure the performance of our schemes in terms of network lifetime and event loss percentage.

关键词： wireless sensor network cognitive power management learning automata external regret zero-sum game

Use of quince seed mucilage edible films containing natural preservatives to enhance physico-chemical quality of rainbow trout fillets during cold storage

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Food Science and Human Wellness 2014年第2期3卷 65-72页

作者： Mohammad Jouki seyed Ali mortazavi Farideh tabatabaei Yazdi Arash Koocheki Naimeh Khazaei Department of Food Science and Technology Faculty of AgricultureFerdowsi University of MashhadP.O.Box 91775-1163MashhadIran Department of Food Science and Technology Faculty of AgricultureUniversity of UrmiaUrmiaIran

In this study quality changes of rainbow trout fillet wrapped with quince seed mucilage QSM film incorporated with 0–2%(V/V)thyme or oregano essential oil,as natural preservatives,during storage of 18 d at 4◦C were *** control and wrapped fillet samples were analyzed for texture,lipid oxidation,and color *** 6 d of storage,a significantly increasing trend was observed for lipid oxidation in control *** values(PV)varied for all treatments and remained lower than 8 meq/kg throughout the storage time(18 d).The lowest PV was obtained in fillets wrapped with QSM film containing 2%oregano essential *** to control samples,fillet samples wrapped with QSM films presented a significant reduction in pH after 12 d(P<0.05).L*and b*color parameters were increased while parameter a*was decreased linearly for all treatments during the storage time.

关键词： fillet treatment film

Suspended sediment load prediction using non-dominated sorting genetic algorithm Ⅱ

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International Soil and Water Conservation Research 2019年第2期7卷 119-129页

作者： Mahmoudreza tabatabaei Amin Salehpour Jam seyed Ahmad Hosseini Soil Conservation and Watershed Management Research Institute Agricultural ResearchEducation and Extension Organization(AREEO)TehranIran

Awareness of suspended sediment load (SSL) and its continuous monitoring plays an important role in soil erosion studies and watershed *** the common use of the conventional model of the sediment rating curve (SRC) and the methods proposed to correct it,the results of this model are still not sufficiently *** this study,in order to increase the efficiency of SRC model,a multi-objective optimization approach is proposed using the Non-dominated Sorting Genetic Algorithm Ⅱ (NSGA-Ⅱ) *** instantaneous flow discharge and SSL data from the Ramian hydrometric station on the Ghorichay River,Iran are used as a case *** the first part of the study,using self-organizing map (SOM),an unsupervised artificial neural network,the data were clustered and classified as two homogeneous groups as 70% and 30% for use in calibration and evaluation of SRC models,*** the second part of the study,two different groups of SRC model comprised of conventional SRC models and optimized models (single and multi-objective optimization algorithms) were extracted from calibration data set and their performance was *** comparative analysis of the results revealed that the optimal SRC model achieved through NSGA-Ⅱ algorithm was superior to the SRC models in the daily SSL estimation for the data used in this *** that the use of the SRC model is common,the proposed model in this study can increase the efficiency of this regression model.

关键词： Clustering Neural network Non-dominated sorting genetic algorithm Ⅱ (NSGA-Ⅱ) Sediment rating curve Self-organizing map

Commentary regarding “on-orbit sleep problems of astronauts and countermeasures”

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Military Medical Research 2019年第2期6卷 178-182页

作者： Joseph John Bevelacqua seyed Mohammad Javad mortazavi Bevelacqua Resources 343Adair DriveRichland WA99352USA Department of Electrical Engineering Biophotonics LabUniversityof Wisconsin Milwaukee3200N Cramer StMilwaukee WI53211USA Doss Lab(R-432) Fox Chase Cancer Center333Cottman AvenuePhiladelphia PA19111USA

This commentary addresses the article by Wu et al. entitled 'On-orbit sleep problems of astronauts and countermeasures'. In this article, the authors discussed the sleep problems of astronauts. Despite its challenging topic, the paper authored by Wu et al. has at least one major shortcoming. This issue is related to the observation that the sleep pattern of astronauts can be disturbed by light flash phenomenon. Since the first report by astronaut E.E. Aldrin in 1969, many astronauts have reported light flashes. These visually perceived flashes of light occurred in different shapes but they apparently moved across the visual field of astronauts and possibly caused, at least to some extent, sleep problems. Moreover, the countermeasures proposed by the authors may improve astronauts’ sleep pattern, but they do not address the root cause of the light flashes(i.e., heavy ion interactions outside the shielding provided by the Earth’s magnetosphere). A possible approach to reducing light flashes is available using the fact that much of the galactic cosmic radiation(GCR) spectrum is composed of ions that can be diverted from the spacecraft using electromagnetic fields. Possible design parameters and the requisite electric and magnetic field strengths to successfully deflect GCR radiation are outlined.

关键词： Space radiation Astronauts Sleep problems Light flashes Phosphenes

Carbon Isotope Stratigraphy of the Uppermost Aptian-Lower Cenomanian Strata from the Lut Block,East Iran

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Journal of Earth Science 2023年第6期34卷 1793-1799页

作者： Javad Sharifi seyed Naser Raisossadat Maryam mortazavi Mehrizi Maryam Motamedalshariati Department of Geology Faculty of ScienceUniversity of BirjandBirjandIran Earth Sciences Research Group University of BirjandBirjandIran

The Mid-Cretaceous interval has been recognized as a crucial period in Earth’s history,and a number of studies on Neo-Tethyan successions illustrate intense evolutions in the nature of Mid-Cretaceous ocean chemistry,sea level,and marine faunal ***,much less investigations have been conducted in the Sistan Ocean,in the eastern ***,the Nimbolook Section(Lut Block,central Iran)has provided an opportunity to address these shortcomings and provide a better understanding of the paleoenvironmental changes in this *** biostratigraphic analysis and age interpretation of the Nimbolook Section have been performed in earlier investigations by means of planktonic foraminifera,ammonites and calcareous *** provides a reliable age framework for the chemostratigraphic *** the Nimbolook Section,the δ^(13)C stratigraphy was carried out on a total of 41 samples,which ranged between -3.26‰and 2.86‰ with an average of 1.09‰(standard deviation=1.15‰),and expanded within the upper Aptian to lower Cenomanian ***,there is a prominent negative shift at the base of the section,accompanied by episodes of sea-level ***,according to the age-diagnostic calcareous nannofossils records,this carbon isotope negative shift(0.88‰ to -3.26‰)straddle between late Aptian and early Albian ***,these new chemostratigraphic observations could be interpreted as being the coeval data from the reference well-studied successions in the other parts of the world,tentatively reflecting the oceanic anoxic event(OAE)1b.

关键词： Aptian-Albian Lut Block carbon isotope stratigraphy geochemistry Iran

Traditional and modern aspects of hemorrhoid treatment in Iran:a review

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Journal of Integrative Medicine 2018年第2期16卷 90-98页

作者： Sahar Dehdari Homa Hajimehdipoor Somayeh Esmaeili Rasool Choopani seyed Alireza mortazavi Student Research Committee Department of Traditional PharmacySchool of Traditional MedicineShahid Beheshti University of Medical Sciences Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy School of Traditional MedicineShahid Beheshti University of Medical Sciences Department of Traditional Medicine School of Traditional MedicineShahid Beheshti University of Medical Sciences Department of Pharmaceutics School of PharmacyShahid Beheshti University of Medical Sciences

Hemorrhoidal disease is a prevalent anorectal condition which is generally not managed well with cur- rent pharmacologic interventions. However, in Iranian traditional medicine （ITM） there are numerous plants with hemorrhoid-healing properties. The present research assembled plants with hemorrhoid- healing properties in ITM; their related pharmacological effects, phytochemical constituents and mech- anisms of action in the modern medicine were also gathered. For this purpose, leading ITM textbooks were searched for plants with hemorrhoid-healing effects. Further, in vitro, in vivo and clinical studies on the most cited species were considered using scientific databases. Studying ITM textbooks revealed 37 medicinal plants with hemorrhoid-healing effects. Among the mentioned herbal medicines, six species, including Allium ampeloprasum, Phyllanthus emblica, Aloe vera, Terminalia chebula, Vitis vinifera and Comrniphora mukul, had the largest number of related pharmacological effects documented in scientific databases. These herbs from ITM should be considered as important resources for producing novel drugs for hemorrhoid treatment.

关键词： Clinical study HemorrhoidsIn vitro In vivoPlants Iranian traditional medicine

Epidemiological aspects of ocular superglue injuries

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International Journal of Ophthalmology(English edition) 2016年第2期9卷 278-281页

作者： seyed Ali tabatabaei Shokoufeh Modanloo Arezoo Mohammadkhani Ghiyasvand Abolghasem Pouryani Mohammad Soleimani seyed Mehdi tabatabaei Ahmad Reza Pakrah Hamideh Masarat Eye Research Center Farabi Eye Hospital Tehran University of Medical Sciences

AIM： To report the frequency, associated risk factors and characteristics of cases referred to Farabi Eye Hospital with ocular superglue injuries. METHODS： In a descriptive cross-sectional study conducted between December 2012 and February 2013, patients with ocular superglue injuries were evaluated. Age, sex, educational level, location, time, mechanism, type, site and time of eye injury were gathered through interview using a customized questionnaire. All participants had given consent to undergo thorough eye examination. RESULTS： Over the course of three months, 105 patients with ocular superglue injuries enrolled in the study, including 56 （53.3%） men and 49 （46.7%） women with the mean age of 24.7±11.6 （range, 2 to 53）y. The right eye, left eye and both eyes were involved in 52%, 42% and 6% of the patients, respectively. Most of injuries had occurred at home （72.4%） and at night （55%）. More than half of patients （52.4%） did not take any primary aids following the ocular injury. Patient carelessness （78.1%）, childhood curiosity and lack of parental supervision （11.4%）, storing superglue in inappropriate places and inadvertently using superglue as eye drops due to poor vision （2.9%）, inadequate awareness of superglue applications [used to stick on artificial nails （3.8%）, artificial eyelashes （1.9%） and broken tooth （1%）] and being assaulted with glue （1%） were common risk factors. CONCLUSION： The frequency of ocular superglue injuries in patients referred to Farabi Eye Hospital is relatively high. This finding underlines the importance of public education and awareness about superglue injuries to the eye and taking protective measures and safety strategies in order to prevent these injures.

关键词： eye injuries superglue risk factors

Complications of intrastromal bevacizumab injection in lamellar keratoplasty

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International Journal of Ophthalmology(English edition) 2020年第2期13卷 356-358页

作者： Mohammad Soleimani Ahad Shahbazi Nader Mohammadi seyed Ali tabatabaei Ocular Trauma and Emergency Department Eye Research CenterFarabi Eye HospitalTehran University of Medical SciencesTehran ***Iran

Dear Editor,We would like to report complications of intrastromal bevacizumab injection for corneal neovascularization(CNV)after lamellar keratoplasty(LK)in two *** is a significant risk factor for graft *** leads to graft failure by disturbing the immune function of the cornea after penetrating keratoplasty(PKP).Studies reported that more than fifty percent of graft failure occurs in this condition[1].

关键词： bevacizumab Complications lamellar keratoplasty