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Influence of Zn and Mg Alloying on the Corrosion Resistance Properties of Al Coating Applied by Arc Thermal Spray Process in Simulated Weather Solution

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Acta Metallurgica Sinica(English Letters) 2018年第6期31卷 591-603页

作者： Han-seung Lee seung-jun kwon Jitendra Kumar Singh Mohamed A.Ismail Department of Architectural Engineering Hanyang University Department of Civil Engineering Hannam University Department of Civil and Construction Engineering Faculty of Engineering and ScienceCurtin University Malaysia

In this study,Al–Zn and Al–Mg coatings were deposited on steel substrates by an arc thermal spray process.X-ray diffraction and scanning electron microscopy were used to characterize the deposited coatings and corrosion *** circuit potential（OCP）,electrochemical impedance spectroscopy,and potentiodynamic studies were used to assess the corrosion characteristics of these coatings after exposure according to the Society of Automotive Engineers（SAE）J2334 solution of varying *** solution simulates an industrial environment and contains chloride and carbonate ions that induce corrosion of the deposited ***,the Al–Mg alloy coating maintained an OCP of approximately-0.911 V versus Ag/Ag Cl in the SAE J2334 solution even after 792 h of *** indicates that it protects the steel sacrificially,whereas the Al–Zn coating provides only barrier-type protection through the deposition of corrosion *** Al–Mg coating acts as a self-healing coating and provides protection by forming Mg_6Al_2（OH）_（16）CO_3（Al–Mg layered double hydroxides）.Mg_6Al_2（OH）_（16）CO_3has interlocking characteristics with a morphology of plate-like nanostructures and an ion-exchange ability that can improve the corrosion resistance properties of the *** presence of Zn in the corrosion products of the Al–Zn coating allows dissolution,but,at the same time,Zn_5（OH）_6（CO_3）_2and Zn_6Al_2（OH）_（16）CO_3are formed and act to reduce the corrosion rate.

关键词： Self-healing coating Corrosion Arc thermal spray Electrochemical impedance spectroscopy

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Comprehensive molecular characterization to predict immunotherapy response in advanced biliary tract cancer:a phase II trial of pembrolizumab

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Oncology Research 2025年第1期33卷 57-65页

作者： RYUL KIM JOO KYUNG PARK MINSUK kwon MINAE AN junG YONG HONG JOON OH PARK SUNG HEE LIM seung TAE KIM Division of Hematology-Oncology Department of MedicineSamsung Medical CenterSungkyunkwan University School of MedicineSeoulKorea Division of Gastroenterology Department of MedicineSamsung Medical CenterSungkyunkwan University School of MedicineSeoulKorea Department of Hematology-Oncology Ajou University School of MedicineSuwon-siGyeonggi-doKorea Samsung Advanced Institute of Health Science and Technology Sungkyunkwan University School of MedicineSeoulKorea

Background:Immune checkpoint inhibitors(ICIs)are effective in a subset of patients with metastatic solid ***,the patients who would benefit most from ICIs in biliary tract cancer(BTC)are still *** and methods:We molecularly characterized tissues and blood from 32 patients with metastatic BTC treated with the ICI pembrolizumab as second-line ***:All patients had microsatellite stable(MSS)type *** of the 32 patients achieved partial response(PR),with an objective response rate(ORR)of 9.4%(95%confidence interval[CI],2.0–25.2)and nine showed stable disease(SD),exhibiting a disease control rate(DCR)of 37.5%(95%CI,21.1–56.3).For the 31 patients who had access to PD-1 ligand 1(PD-L1)combined positive score(CPS)testing(cut-off value≥1%),the ORR was not different between those who had PD-L1-positive(PD-L1+;1/11,9.1%)and PDL1-(2/20,10.0%)tumors(p=1.000).The tumor mutational burden(TMB)of PD-L1+BTC was comparable to that of PD-L1-BTC(p=0.630).TMB and any exonic somatic mutations were also not predictive of pembrolizumab *** analysis of blood and tumor samples demonstrated a relatively high natural killer(NK)cell proportion in the peripheral blood before pembrolizumab treatment in patients who achieved tumor ***,the tumors of these patients presented high enrichment scores for NK cells,antitumor cytokines,and Th1 signatures,and a low enrichment score for cancer-associated ***:This study shows the molecular characteristics associated with the efficacy of pembrolizumab in BTC of the MSS type.

关键词： Pembrolizumab Whole-exome sequencing Whole-transcriptome sequencing Biliary tract cancer

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Adaptive Consistent Management to Prevent System Collapse on Shared Object Manipulation in Mixed Reality

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Computers, Materials & Continua 2023年第4期75卷 2025-2042页

作者： jun Lee Hyun kwon Department of Game Software Hoseo UniversityAsan-siKorea Department of Artificial Intelligence and Data Science Korea Military AcademySeoulKorea

A concurrency control mechanism for collaborative work is akey element in a mixed reality environment. However, conventional lockingmechanisms restrict potential tasks or the support of non-owners, thusincreasing the working time because of waiting to avoid conflicts. Herein, wepropose an adaptive concurrency control approach that can reduce conflictsand work time. We classify shared object manipulation in mixed reality intodetailed goals and tasks. Then, we model the relationships among goal,task, and ownership. As the collaborative work progresses, the proposedsystem adapts the different concurrency control mechanisms of shared objectmanipulation according to the modeling of goal–task–ownership. With theproposed concurrency control scheme, users can hold shared objects andmove and rotate together in a mixed reality environment similar to realindustrial sites. Additionally, this system provides MS Hololens and Myosensors to recognize inputs from a user and provides results in a mixed realityenvironment. The proposed method is applied to install an air conditioneras a case study. Experimental results and user studies show that, comparedwith the conventional approach, the proposed method reduced the number ofconflicts, waiting time, and total working time.

关键词： Mixed reality upper body motion recognition shared object manipulation adaptive task concurrency control

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Randomized clinical trial of a bladder neck plication stitch during robot-assisted radical prostatectomy

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Asian Journal of Andrology 2015年第2期17卷 304-308,I0011页

作者： seung-kwon Choi Sejun Park Hanjong Ahn Department of Urology University of Ulsan College of Medicine Asan Medical Center Seoul Korea Department of Urology University of Ulsan College of Medicine Ulsan University Hospital Utsan Korea

Urinary incontinence after robot-assisted radical prostatectomy （RARP） is one of the most bothersome complications affecting patients＇ daily lives. The efficacy of the bladder neck plication stitch technique in promoting an earlier return of continence was prospectively evaluated in 158 patients who underwent RARP for clinically localized prostate cancer by a single surgeon at our institute from March 2012 to January 2013. Patients were randomized 1：1 to undergo surgery with （n = 79） or without （n = 79） the bladder neck plication stitch, and their time to recovery from incontinence, defined as being pad free, was compared. Recovery from incontinence at 1, 3, and 6 months were observed in 22 （27.8%）, 42 （53.2%）, and 57 （72.2%） patients, respectively, treated with, and 23 （29.1%）, 47 （59.5%）, and 59 （74.7%） patients, respectively, treated without the bladder neck plication stitch, with no significant difference in time to recovery from incontinence between the two groups. Multivariate analysis showed that age, membranous urethral length and shape of the prostatic apex on magnetic resonance imaging were independent predictors of early recovery from urinary incontinence after RARP. The bladder neck plication stitch had no effect on time to recovery from postoperative urinary incontinence following RARR

关键词： prostatectomy prostatic neoplasms urinary incontinence urologic surgical procedures

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Improvement in the Adhesion Between Electrode of a SOFC and Ag Paste as a Current Collector by Au Deposition

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Journal of Materials Science & Technology 2015年第3期31卷 257-263页

作者： Sang Koo Jeon seung Hoon Nahm Oh Heon kwon Department of Safety Engineering Pukyong National University Center for Energy Materials Metrology Korea Research Institute or Standards and Science

This paper reports the use of Au films to improve the performance of the stacked solid oxide fuel cell(SOFC) based on the characterization of the interface and the adhesion between the electrodes of the SOFCs and the Ag paste. The specimens were manufactured to perform the experiment as follows. A Si O2 wafer with a 300 mm notch was attached to the electrodes of a SOFC by a Ag paste and Au film, which were deposited on the electrodes by sputtering for 1 min or 5 min deposition time and annealed at300 C for 1 h. The four-point bending test was performed, which resulted in the formation of an extended crack at the tip on the wafer notch, and the crack propagation was observed using a stereo microscope equipped with a charge-coupled device(CCD). Consequently, the interfacial adhesion energy and the effect of the Au film between the each electrode and the Ag paste can be evaluated. On the cathode, the interfacial adhesion energy without Au film was 2.59 J/m2(upper value) and the adhesion energy increased to 11.59 J/m2(upper value) and 15.89 J/m2(lower value) with the Au film. On the anode,the interfacial adhesion energy without Au film was 1.74 J/m2(upper value), which increased to 11.07 J/m2(upper value) and 14.74 J/m2(lower value) with the Au film. In addition, the interface areas were analyzed by scanning electron microscopy(SEM) and energy dispersive spectroscopy(EDS) to estimate the interface delamination.

关键词： Solid oxide fuel cell Au film Interfacial adhesion

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Recent progress and future directions of the research on nanoplastic-induced neurotoxicity

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Neural Regeneration Research 2024年第2期19卷 331-335页

作者： seung-Woo Han Jinhee Choi kwon-Yul Ryu Department of Life Science University of SeoulSeoulSouth Korea School of Environmental Engineering University of SeoulSeoulSouth Korea

Many types of plastic products,including polystyrene,have long been used in commercial and industrial *** and nanoplastics,plastic particles derived from these plastic products,are emerging as environmental pollutants that can pose health risks to a wide variety of living organisms,including ***,it is not well understood how microplastics and nanoplastics affect cellular functions and induce stress *** can be exposed to polystyrene-microplastics and polystyrene-nanoplastics through ingestion,inhalation,or skin *** ingested plastics are excreted from the body,but inhaled plastics may accumulate in the lungs and can even reach the brain via the nose-to-brain ***-sized polystyrene-nanoplastics can enter cells by endocytosis,accumulate in the cytoplasm,and cause various cellular stresses,such as inflammation with increased pro-inflammatory cytokine production,oxidative stress with generation of reactive oxygen species,and mitochondrial *** induce autophagy activation and autophagosome formation,but autophagic flux may be impaired due to lysosomal *** permanently exposed to polystyrene-nanoplastics,they can be removed from cells by exocytosis and subsequently restore cellular ***,neurons are very susceptible to this type of stress,thus even acute exposure can lead to neurodegeneration without *** review focuses specifically on recent advances in research on polystyrene-nanoplastic-induced cytotoxicity and ***,in this review,based on mechanistic studies of polystyrene-nanoplastics at the cellular level other than neurons,future directions for overcoming the negative effects of polystyrene-nanoplastics on neurons were suggested.

关键词： autophagy cellular stress cytotoxicity endocytosis exocytosis inflammation microplastics nanoplastics neurotoxicity oxidative stress polystyrene

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Laser‑Induced and MOF‑Derived Metal Oxide/Carbon Composite for Synergistically Improved Ethanol Sensing at Room temperature

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Nano-Micro Letters 2024年第6期16卷 210-220页

作者： Hyeongtae Lim Hyeokjin kwon Hongki Kang Jae Eun Jang Hyuk‑jun kwon Department of Electrical Engineering and Computer Science DGISTDaegu 42988South Korea Convergence Research Advanced Centre for Olfaction DGISTDaegu 42988South Korea

Advancements in sensor technology have significantly enhanced atmospheric ***,metal oxide and carbon(MO_(x)/C)hybrids have gained attention for their exceptional sensitivity and room-temperature sensing ***,previous methods of synthesizing MO_(x)/C composites suffer from problems,including inhomogeneity,aggregation,and challenges in ***,we introduce a refined method that employs a metal–organic framework(MOF)as a precursor combined with direct laser *** inherent structure of MOFs ensures a uniform distribution of metal ions and organic linkers,yielding homogeneous MO_(x)/C *** laser processing facilitates precise micropatterning(<2μm,comparable to typical photolithography)of the MO_(x)/C *** optimized MOF-derived MO_(x)/C sensor rapidly detected ethanol gas even at room temperature(105 and 18 s for response and recovery,respectively),with a broad range of sensing performance from 170 to 3,400 ppm and a high response value of up to 3,500%.Additionally,this sensor exhibited enhanced stability and thermal resilience compared to previous MOF-based *** research opens up promising avenues for practical applications in MOF-derived sensing devices.

关键词： Metal-organic frameworks Metal oxide Carbon composite Laser Gas sensor

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Inversion of two-phase extensional basin systems during subduction of the Paleo-Pacific Plate in the SW Korean Peninsula:Implication for the Mesozoic “Laramide-style” orogeny along East Asian continental margin

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Geoscience Frontiers 2019年第3期10卷 909-925页

作者： seung-Ik Park jungrae Noh Hee jun Cheong Sanghoon kwon Yungoo Song Sung Won Kim M.Santosh Department of Geology Kyungpook National University Department of Earth System Sciences Yonsei University School of Earth Sciences The Ohio State University Geology Division Korea Institute of Geoscience and Mineral Resources School of Earth Sciences and Resources China University of Geosciences Department of Earth Sciences University of Adelaide

During subduction, continental margins experience shortening along with inversion of extensional sedimentary basins. Here we explore a tectonic scenario for the inversion of two-phase extensional basin systems, where the Early-Middle Jurassic intra-arc volcano-sedimentary Oseosan Volcanic Complex was developed on top of the Late Triassic-Early Jurassic post-collisional sequences, namely the Chungnam Basin. The basin shortening was accommodated mostly by contractional faults and related folds. In the basement, regional high-angle reverse faults as well as low-angle thrusts accommodate the overall shortening, and are compatible with those preserved in the cover. This suggests that their spatial and temporal development is strongly dependent on the initial basin geometry and inherited *** in transport direction observed along the basement-sedimentary cover interface is a characteristic structural feature, reflecting sequential kinematic evolution during basin inversion. Propagation of basement faults also enhanced shortening of the overlying sedimentary cover sequences. We constrain timing of the Late Jurassic-Early Cretaceous(ca. 158-110 Ma) inversion from altered K-feldspar 40 Ar/39 Ar ages in stacked thrust sheets and K-Ar illite ages of fault gouges, along with previously reported geochronological data from the area. This "non-magmatic phase" of the Daebo Orogeny is contemporaneous with the timing of magmatic quiescence across the Korean Peninsula. We propose the role of flat/low-angle subduction of the Paleo-Pacific Plate for the development of the "Laramide-style" basement-involved orogenic event along East Asian continental margin.

关键词： Two-phase extensional basin systems Paleo-Pacific Plate Inversion tectonics “Laramide-style” orogeny East Asian continental margin

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Spatial Multi-Presence System to Increase Security Awareness for Remote Collaboration in an Extended Reality Environment

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Intelligent Automation & Soft Computing 2023年第7期37卷 369-384页

作者： jun Lee Hyun kwon Department of Game Software Hoseo UniversityAsan-siKorea Department of Artificial Intelligence and Data Science Korea Military AcademySeoulKorea

Enhancing the sense of presence of participants is an important issue in terms of security awareness for remote collaboration in extended ***,conventional methods are insufficient to be aware of remote situations and to search for and control remote *** study pro-poses a spatial multi-presence system that simultaneously provides multiple spaces while rapidly exploring these spaces as users perform collaborative work in an extended reality *** proposed system provides methods for arranging and manipulating remote and personal spaces by creating an annular screen that is invisible to the *** user can freely arrange remote participants and their workspaces on the annular *** users can simultaneously view various spaces arranged on the annular screen,they can perform collaborative work while simultaneously feeling the presence of multiple spaces and can be fully immersed in a specific *** addition,the personal spaces where users work can also be arranged through the annular *** to the results of the performance evaluations,users participating in remote collaborative works can visualize the spaces of multiple users simultaneously and feel their presence,thereby increasing their understanding of the ***,the proposed system reduces the time to perform tasks and gain awareness of the emergency in remote workspaces.

关键词： Extended reality spatial presence multi presence security awareness

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Horizontal distribution of Changjiang Diluted Water in summer inferred from total suspended sediment in the Yellow Sea and East China Sea

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Acta Oceanologica Sinica 2015年第12期34卷 44-50页

作者： LEE Dong-Kyu kwon Jae-Il SON seung Hyun Pusan National University Coastal Disaster Research Center Korea Institute of Ocean Science and Technology China-Korea Joint Ocean Research Center Cooperative Institute for Research in the Atmosphere Colorado State University

During the summer in the Yellow Sea and East China Sea, the resuspension of the bottom sediment is obstructed by strong stratification and, as a result, the concentration of total suspended sediment（TSS） can be used as an excellent tracer for Changjiang Diluted Water（CDW）. To analyze the spatial and temporal variations of the CDW distribution, the monthly mean TSS from Moderate Resolution Imaging Spectroradiometer（MODIS） ocean color data are constructed and are converted to salinity using the relationship between salinity observed from AQUARIUS and TSS. The process produces the detailed horizontal distribution of salinity with very high resolution（1 km）. From monthly mean salinity map from 2002 to 2012 in July and August, the expansion patterns of CDW are analyzed. The southerly wind in July and southeasterly wind in August transport the CDW eastward and northeastward, respectively. It is found that the yearly variation of the expansion of CDW toward the southern sea area of Korea is mostly due to the variation of southerly wind and the fluctuations of fresh water discharge into the Changjiang estuary show relatively little impact on the eastward extend of CDW. When 11-year mean（from2002 to 2012） salinity map in August is compared with World Ocean Atlas 2013, it is revealed that wind in August strengthened six times from 1994 and it causes the expansion of CDW extended 150 km further eastward.

关键词： Yellow and East China Seas Changjiang diluted water total suspended sediment MODIS

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