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Journal of Integrative Medicine 2014年第3期 298-298页

作者： Reginaldo Silva Filho sergio Pavliuk Ellen Cristina da Silva Dafne Pretel

Objective: To evaluate the effectiveness of the crossing method of point selection associated with the effects of external application of different substances listed as Chinese Materia ***: A total of 127 patients were recruited from EbRAMEC's regular ambulatory clinic after reading and signing the consenting *** subjects were divided in a randomized way into 4 different groups: A: Fuzi(Radix Aconiti Lateralis Preparata) 34; b: baijiezi(Semen Sinapis) 31; C: Yanhusuo(Corydalis Rhizome) 38; D: control group with regular rice(Oryza Sativa) *** acupoints were selected using the crossing method, where points in one side of the body are used for the other side, based on these associations: shoulder-hip, elbow-knee, wrist-ankle, and *** selection of the acupoints, a piece of the Chinese Materia Medica according to each group was pressed and taped on the *** patient was evaluated by the Visual Analog Scale(VAS) before and after the ***: All subjects presented a better evaluation after treatment compared to before treatment, including control *** treatment groups presented significant improvement on *** statistic analysis showed that immediate improvement efficacy of each was as follows: A: 51.52%, b: 72.63%, C: 62.08% and D: 54.47%.Conclusion: based on the results we can conclude that the classical crossing method for selecting acupoints is *** external application of Chinese Materia Medica on acupoints is a valid and efficient therapy and baijiezi presented to be the most efficient one on this *** strongly suggest that larger studies with better methods should be conducted.

关键词： VAS IMMEDIATE EFFECT OF EXTERNAL ACUPOINT APPLICATION OF DIFFERENT HERbS ON JOINT AND MUSCLE PAIN THROUGH CROSSING METHOD

Innovate combination of sevoflurane dilution in dimethyl sulfoxide: A stability study by gas chromatography and nuclear magnetic resonance

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World Journal of Pharmacology 2016年第3期5卷 59-67页

作者： F Dámaso Fernández-Ginés sergio García-Mu?oz Héctor Mateo-Carrasco Miguel ángel Rincón-Cervera Manuel Corti?as-Sáenz José Antonio Morales-Molina Carmen Fernández-Sánchez Juan Miguel Expósito-López Ignacio Rodríguez-García Department of Pharmacy Torrecárdenas Hospital University of Almería Aseptic Services Unit Department of Pharmacy Northampton General Hospital Institute of Nutrition and Food Technology University of Chile Department of Anesthesiology and Pain Management Torrecárdenas Hospital Department of Pharmacy Agencia Pública Empresarial Sanitaria Hospital de Poniente Department of Chemistry and Physics University of Almería

To investigate physicochemical stability of sevofuranein dimethyl sulfoxide using gas chromatography with a fame ionization detector and nuclear magnetic reso-nance （NMR）.METHODSUndiluted sevoflurane, plus dilutions 1：2, 1：5, 1：10, 1：25, and 1：50 in dimethyl sulfoxide were prepared in a vertical laminar fow cabinet class Ⅱ type b and stored at different temperatures （23 ℃, 6 ℃, and -10 ℃） for 45 d. Sterile 1 mL polypropylene amber syringes to minimize light degradation, caps and needles were used. The presence of sevofurane and its degradation products in the samples was determined by gas chroma-tography with flame ionization detector （260 ℃, 40min）, and by 1H, 19F, and proton-decoupled 19F nuclearmagnetic *** The gas chromatography analysis showed sevofluraneand dimethyl sulfoxide （DMSO） retention times were 2.7and 13.0 min, respectively. Pure DMSO injection into thecolumn resulted in two additional peaks at 2.1 and 2.8min. The same sevofurane peak at 2.7 min was observedin all the dilutions at -10 ℃, 4 ℃ and 25 ℃. The NMRspectra showed signals consistent with the sevoflurane structure in all the dilutions at -10 ℃, 4 ℃ and 25 ℃. In the 1H spectrum, two signals corresponding to the sevoflurane molecule were observed at 5.12 and 4.16 parts per million （ppm5）. In the 19F-NMR spectrum, two signals were observed at -76.77 ppm and -157.13 ppm. In the 19F NMR CPD, two signals were observed at -76.77 ppm and -157.13 ppm. The first one showed a doublet （JF-F = 3.1 Hz） which integrated by six fluorine nuclei from the hexafluoro-isopropyl group. The second signal was integrated by a fuorine atom and showed a septuplet （JF-F = 3.1 Hz）.CONCLUSIONThis study shows that different concentrations ofsevofurane in dimethyl sulfoxide retain their chemicalcomposition after exposure to different temperaturesfor a period of 45 d.

关键词： Sevoflurane Dimethyl sulfoxide Uclear magnetic resonance Gas chromatography Skin ulcers Drug stability

Possible association between hepatitis C virus and malignancies different from hepatocellular carcinoma:A systematic review

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World Journal of Gastroenterology 2015年第45期21卷 12896-12953页

作者： Sirio Fiorino Letizia bacchi-Reggiani Dario de biase Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Giorgia Acquaviva Luca di Tommaso Arrigo bondi Michela Visani sergio Sabbatani Laura Pontoriero Carlo Fabbri Andrea Cuppini Annalisa Pession Elio Jovine Unità Operativa di Medicina Interna Ospedale di Budrio Dipartimento di Medicina Sperimentale Istituto di Cardiologia Policlinico S. Orsola-Malpighi Università degli Studi di Bologna Dipartimento di Medicina Sperimentale Università di Bologna Unità Operativa Biologia Molecolare Anatomia Patologica Ospedale Bellaria Servizio di Anatomia Patologica Ospedale Maggiore Unità Operativa di Chirurgia A Ospedale Maggiore Institute of Neuroscience National Research Council Humanitas Clinical and Research Center Rozzano Dipartimento di Farmacia e biotecnologie Università di Bologna Istituto di Malattie Infettive Policlinico S. Orsola-Malpighi Università degli Studi di Bologna Unità di Cura Materno-Infantile Distretto Lametino U.O. Endoscopia Ospedale Maggiore

AIM: To summarize the current knowledge about the potential relationship between hepatitis C virus(HCV) infection and the risk of several extra-liver cancers. METHODS: We performed a systematic review of the literature, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis(PRISMA) Statement. We extracted the pertinent articles, published in MEDLINE and the Cochrane Library, using the following search terms: neoplasm/cancer/malignancy/tumor/carcinoma/adeno-carcinoma and non-Hodgkin lymphomas, kidney/renal-, cholangio-, pancreatic-, thyroid-, breast-,oral-, skin-, prostate-, lung-, colon-, stomach-, haematologic. Case series, case-series with control-group, case-control, cohort-studies as well as meta-analyses, written in English were collected. Some of the main characteristics of retrieved trials, which were designed to investigate the prevalence of HCV infection in each type of the above-mentioned human malignancies were summarised. A main table was defined and included a short description in the text for each of these tumours, whether at least five studies about a specific neoplasm, meeting inclusion criteria, were available in literature. According to these criteria, we created the following sections and the corresponding tables and we indicated the number of included or excluded articles, as well as of meta-analyses and reviews:(1) HCV and haematopoietic malignancies;(2) HCV and cholangiocarcinoma;(3) HCV and pancreatic cancer;(4) HCV and breast cancer;(5) HCV and kidney cancer;(6) HCV and skin or oral cancer; and(7) HCV and thyroid cancer. RESULTS: According to available data, a clear correlation between regions of HCV prevalence and risk of extra-liver cancers has emerged only for a very small group of types and histological subtypes of malignancies. In particular, HCV infection has been associated with:(1) a higher incidence of some b-cell Non-HodgkinLymphoma types, in countries, where an elevated prevalence of this pathogen is de

关键词： Neoplasm Cancer Hepatitis C virus Risk factors Ext

Anaerobic Co-digestion Process Efficiency Estimation in Phases as an Alternative for Municipal Waste Treatment

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Journal of Environmental Science and Engineering(b) 2021年第1期10卷 9-19页

作者： María Montes Alejandra Vásquez Pedro García sergio Zamora Naim Sulvarán Viniza Ureña Department of Environmental Engineering Institute for EngineeringUniversity of VeracruzBoca del RioVer 94294Mexico Graduate Department Faculty of Construction Engineering and HabitatUniversity of VeracruzBoca del RioVer 94294Mexico Department of Chemical Engineering Faculty of Chemical SciencesUniversity of VeracruzBoca del RioVer 94294Mexico

The incorrect disposal of the waste generated in the municipalities contributes to water and soil contamination,resulting in a real concern in order to find an adequate disposal as well as obtain by-products that can be used to reduce CO2 *** digestion turns out to be the most efficient treatment,both in environmental and economic *** objective of this study is to evaluate the anaerobic co-digestion process in phases as an alternative for the treatment of municipal waste:sludge from water treatment plants and the biodegradable part of Municipal Solid Waste(MSW),for three HRTs(Hydraulic Retention Times).Testing results show up a max elimination of 70.68%in VS(Volatile Solids)and 74.01%in COD(Chemical Oxygen Demand).With these percentages of elimination on average,15.96 L/d of biogas was produced,for each kg of COD eliminated 0.56 m3 of biogas was produced and for each kg of SV 0.85 m3 and methane of 50.10%.

关键词： Co-digestion methane municipal waste

Incremental value of thoracic ultrasound in intensive care units:Indications,uses,and applications

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World Journal of Radiology 2016年第5期8卷 460-471页

作者： biagio Liccardo Francesca Martone Paolo Trambaiolo sergio Severino Gian Alfonso Cibinel Antonello D'Andrea Second University of Naples AORN "dei Colli"Monaldi Hospital Intensive Care Unit Sandro Pertini Hospital Emergency Medicine Unit ASL TO3

Emergency physicians are required to care for unstable patients with life-threatening conditions, and thus must make decisions that are both quick and precise about unclear clinical situations. There is increasing consensus in favor of using ultrasound as a real-time bedside clinical tool for clinicians in emergency settings alongside the irreplaceable use of historical and physical examinations. b-mode sonography is an old technology that was first proposed for medical applications more than 50 years ago. Its application in the diagnosis of thoracic diseases has always been considered limited, due to the presence of air in the lung and the presence of the bones of the thoracic cage, which prevent the progression of the ultrasound beam. However, the close relationship between air and water in the lungs causes a variety of artifacts on ultrasounds. At the bedside, thoracic ultrasound is based primarily on the analysis of these artifacts, with the aim of improving accuracy and safety in the diagnosis and therapy of the various varieties of pulmonary pathologic diseases which are predominantly "water-rich" or "air-rich". The indications, contraindications, advantages, disadvantages, and techniques of thoracic ultrasound and its related procedures are analyzed in the present review.

关键词： Intensive care unit Heart failure Pleural effusion Pneumothorax Echocardiography Thoracic ultrasound

MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis b- and c-related-hepatocellularcarcinoma

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World Journal of Gastroenterology 2016年第15期22卷 3907-3936页

作者： Sirio Fiorino Maria Letizia bacchi-Reggiani Michela Visani Giorgia Acquaviva Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Luca Di Tommaso Arrigo bondi sergio Sabbatani Andrea Domanico Carlo Fabbri Paolo Leandri Annalisa Pession Elio Jovine Dario de biase Unita Operativa di Medicina C Ospedale Maggiore 40133 Bologna Italy Dipartimento di Medicina Sperimentale Istituto di Cardiologia Policlinico S. Orsola-Malpighi Universita degli Studi di Bologna 40138 BolognaItaly Dipartimento di Farmacia e biotecnologie Universita di Bologna 40139 Bologna Italy Dipartimento di Medicina Sperimentale Universita di Bologna Ospedale Bellaria 40139 Bologna Italy Servizio di Anatomia Patologica Ospedale Maggiore 40133 Bologna Italy Unita Operativa di Chirurgia A Ospedale Maggiore 40133 Bologna Italy CNR Institute of Neuroscience Padova Italy 35121 Padova Italy Humanitas Clinical and Research Center 20089 Rozzano Milano Italy Istituto di Malattie Infettive Policlinico S. Orsola-Malpighi Universita degli Studi di Bologna 40138 Bologna Italy Unita Operativa di Medicina Interna A Ospedale Maggiore 40133 Bologna Italy Unita Operativa di Endoscopia Digestiva Ospedale Maggiore 40133 Bologna Italy

Aim of the present review is to summarize the current knowledge about the potential relationship between mi RNAs and hepatitis b virus(HbV)-hepatitis C virus(HCV) related liver diseases. A systematic computerbased search of published articles, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Statement, was performed to identify relevant studies on usefulness of serum/plasma/urine mi RNAs, as noninvasive biomarkers for early detection of HbV and HCV-induced hepatocellular carcinoma(HCC) development, as well as for its prognostic evaluation. The used Medical Subject Headings terms and keywords were: "HbV", "HCV", "hepatocellular carcinoma", "micro RNAs", "mi RNAs", "diagnosis", "prognosis", "therapy", "treatment". Some serum/plasma mi RNAs, including mi R-21, mi R-122, mi-125a/b, mi R-199a/b, mi R-221, mi R-222, mi R-223, mi R-224 might serve as biomarkers for early diagnosis/prognosis of HCC, but, to date, not definitive results or well-defined panels of mi RNAs have been obtained. More well-designed studies, focusing on populations of different geographical areas and involving larger series of patients, should be carried out to improve our knowledge on the potential role of mi RNAs for HCC early detection and prognosis.

关键词： Hepatitis b virus Hepatitis C virus Hepatocellular carcinomas Liver diseases MicroRNAs Review

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城市环境设计 2020年第4期126卷 120-133页

作者：沃尔夫·狄·普瑞克斯 Christopher beccone Guy bébié Lorenz bürgi Wolfgang Fiel Kai Hellat Robert Haranza Alex Jackson Georg Kolmayr Daniel Kerbler Lucas Kulnig Andreas Mieling Marianna Milioni Daniel Moral Jutta Sch?dler Andrea Sch?ning Mario Schwary Markus Schwarz Oliver Tessmann Dionicio Valdez Philipp Vogt Markus Wings Christoph Ziegler Patrick Lhomme Francois Texier Philippe Folliasson Etienne Champenois Alexandru Gheorghe Niels Hiller Emanuele Iacono Pierre-Yves Six sergio Pirrone Duccio Malagamba Raimund Koch

项目大事记/CHRONOLOGY竞赛/Competition:2001初步设计-深化设计/Preliminary Design-Design Development:2002—20041.投标-竞标/Tender-Dialog Competitive:2004—2006第一阶段施工(桩基)/Construction Phase 1:2006—2007停工/Stop of Construction:2007—20092.投标-施工图设计/Tender-Execution Design:2009—2010第二阶段施工/Construction Phase 2:2010—2014竣工/Completion:12/2014

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联合应用氯吡格雷和质子泵抑制剂对急性冠状动脉综合征患者经皮冠状动脉介入术后预后的影响

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中国医药 2017年第2期12卷 161-166页

作者：严研王晓范婧尧聂绍平 sergio Raposeiras-Roubin Emad Abu-Assi Jose Paulo Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose Ramon Gonzalez-Juanatey Stephen b. Wilton Wouter J. Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Testuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis Claudio Correia Masa-aki Kawashiri Sasko Kedev 首都医科大学附属北京安贞医院急诊危重症中心 000029 西班牙比戈市阿尔瓦罗康克雷诺医院心内科 36312 荷兰阿姆斯特丹大学学术医学中心心内科 1105 意大利都灵市圣乔瓦尼巴蒂斯塔医院心内科 10126 美国芝加哥市北岸大学医院心内科 60201 西班牙圣地亚哥·德·孔波斯特拉大学临床医院心内科 15706 加拿大卡尔加里市阿尔伯塔利宾心血管研究所心脏科学医学科 T2N4N1 西班牙马德里市圣卡洛斯医院心内科 28040 西班牙巴塞罗纳市贝尔维尔医院心内科 08907 希腊雅典市佩特雷大学医院心内科 26504 德国法兰克福市基尔霍夫胸腔心脏中心心内科 61231 日本京都大学医学研究生院心内科 606-8507 波兰华沙市临床医院心内科 02-091 日本东京市东海大学医学院心内科 259-1193 巴西萨尔瓦多市圣拉斐尔医院 41253-190 日本金泽大学医学研究生院心内科 920-0942 马其顿斯科普里市临床心脏病诊所心内科 1000

目的探讨联合应用氯吡格雷和质子泵抑制剂（PPI）对急性冠状动脉综合征（ACS）患者经皮冠状动脉介入（PCI）术后预后的影响。方法回顾性分析2003年至2014年来自10个国家（加拿大，巴西，德国，波兰，荷兰，西班牙，意大利，希腊，中国... 详细信息

目的探讨联合应用氯吡格雷和质子泵抑制剂（PPI）对急性冠状动脉综合征（ACS）患者经皮冠状动脉介入（PCI）术后预后的影响。方法回顾性分析2003年至2014年来自10个国家（加拿大，巴西，德国，波兰，荷兰，西班牙，意大利，希腊，中国，日本）15个临床中心的ACS合并PCI术后18077例患者的临床资料。研究氯吡格雷、PPI与ACS患者PCI术后预后的关系。比较患者的基本临床特征、既往病史、生化指标、药物应用，以及终点事件的发生率情况。通过Cox回归模型进行分析及倾向性评分调整其他可能影响患者的预后因素包括人口学信息（年龄、性别）和临床指标，计算PPI这一干预因素的风险比并评价其是否能够明显影响患者的预后。结果基于国际多中心blee MACs注册登记研究分析，排除关键数据缺失过多患者2676例。根据纳入与排除标准及倾向性评分调整整理后，再排除患者6461例，最终列队患者8940例。根据患者用药不同，将患者分为氯吡格雷＋PPI组（4814例）和氯吡格雷组（4126例）。氯吡格雷＋PPI组患者女性、高血压病史、高脂血症病史、糖尿病史、外周血管疾病史、既往急性心肌梗死史、慢性肾功能不全病史、消化道溃疡病史、冠状动脉旁路移植术病史、既往出血病史、恶性肿瘤病史、不稳定型心绞痛、非sT段抬高型心肌梗死、心功能Killip分级≥2级、经皮腔内冠状动脉成形术、出院后血管紧张素转换酶抑制剂／血管紧张素Ⅱ受体拮抗剂应用比例、年龄和入院时血肌酐水平明显高于氯吡格雷组[25．4％（1225／4814）比21．0％（865／4126）、59．9％（2882／4814）比49．2％（2032／4126）、48．3％（2327／4814）比42．7％（1762／4126）、26．4％（1272／4814）比22．1％（910／4126）、8．0％（386／4814）比5．6％（231／4126）、12．3％（593／4814）比10．6％（436／4126）、2．0％（98／4814）比0．7％（30／4126）、2．3％（112／4814）比1．0％（42／4126）、3．6％（172／4814）比2．2％（92／4126）、4．5％（219／4814）比3．0％（123／4126）、8．0％（387／4814）比4．7％（193／4126）、13．4％（644／4814）比9．1％（374／4126）、29．1％（1400／4814）比15．9％（656／4126）、14．5％（699／4814）比11．2％（462／4126）、56．0％（2697／4814）比55．7％（2300／4126）、75．5％（3633／4814）比68．6％（2829／4126）、（66±12）岁比（61±13）岁、（10±6）mg／L比（9±4）mg／L]；且入院时血红蛋白水平和出院后β受体阻滞剂应用比例明显低于氯吡格雷组[（138±19）g／L比（141±16）g／L、80．6％（3880／4814）比83．1％（3428／4126）]，差异均有统计学意义（均P〈0．05）。调整前，氯吡格雷＋PPI组主要终点事件（全因死亡／再发心肌梗死／出血）发生率明显高于氯吡格雷组，差异有统计学意义（风险比为1．331，95％置信区间为1．161-1．524）。调整后，氯吡格雷＋PPI组主要终点事件（全因死亡／再发心肌梗死／出血）发生率与氯吡格雷组比较，差异无统计学意义（风险比为1．036，95％置信区间为0．903-1．189）。结论ACS患者PCI术后联合应用PPI与氯吡格雷是合理的，尤其在胃肠道出血高危患者中。

关键词：急性冠状动脉综合征氯吡格雷质子泵抑制剂预后

急性冠状动脉综合征患者经皮冠状动脉介入术后出血情况分析

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中国医药 2017年第6期12卷 801-805页

作者：严研王晓范婧尧聂绍平宋现涛 sergio Raposeiras-Roubin Emad Abu-Assi Jose Paulo Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose Ramon Gonza1ez-Juanatey Stephen b. Wilton Ivan Nufiez-Gil Albert Ariza-Sole Dimitrios Alexopoulos [ Christoph Liebetrau Testuma Kawaji Zenon Huczek Toshiharu Fujii Luis Claudio Correia Masa-aki Kawashiri Sasko Kedev 首都医科大学附属北京安贞医院急诊危重症中心 100029 首都医科大学附属北京安贞医院心内科 100029 西班牙比戈市阿尔瓦罗康克雷诺医院心内科 36312 荷兰阿姆斯特丹大学学术医学中心心内科 1105 意大利都灵市圣乔瓦尼巴蒂斯塔医院心内科 10126 美国芝加哥市北岸大学医院心内科 60201 西班牙圣地亚哥·德·孔波斯特拉大学临床医院心内科 15706 加拿大卡尔加里市阿尔伯塔省利宾心血管研究所心脏科学医学科 T2N4N1 西班牙马德里市圣卡洛斯医院心内科 28040 西班牙巴塞罗纳市贝尔维尔医院心内科 08907 希腊雅典市佩特雷大学医院心内科 26504 德国法兰克福市基尔霍夫胸腔心脏中心心内科 61231 日本京都大学医学研究生院心内科 606-8507 日本东京市东海大学医学院心内科 259-1193 巴西萨尔瓦多市圣拉斐尔医院心内科 41253-190 日本金泽大学医学研究生院心内科 920-0942 马其顿斯科普里市临床心脏病诊所心内科 1000

目的分析急性冠状动脉综合征（ACS）经皮冠状动脉介入（PCI）术后出血情况。方法回顾性分析2003年1月至2014年12月来自11个国家16个临床中心的18077例行PCI的ACS患者的临床资料。根据是否出现出血事件，将患者分为出血组（558例）和非... 详细信息

目的分析急性冠状动脉综合征（ACS）经皮冠状动脉介入（PCI）术后出血情况。方法回顾性分析2003年1月至2014年12月来自11个国家16个临床中心的18077例行PCI的ACS患者的临床资料。根据是否出现出血事件，将患者分为出血组（558例）和非出血组（17519例），比较2组患者的基本临床特征、手术情况及生化指标。分析ACS患者PCI术后出血相关情况。结果马其顿中心数据因关键变量缺失过多而被排除患者2676例，故最终纳入10个国家15个中心15401例ACS患者。排除缺失数据，本研究共有12910例患者收集到出血部位的数据，409例患者存在出血事件。胃肠道是最常见出血部位，占48．7％（199／409），颅内出血占7．6％（31／409）。Logistic逐步回归方法多因素分析显示，既往出血病史、高血压病史是术后1年内消化道出血的危险因素。排除马其顿中心数据（2676例）与Cox回归模型和倾向性评分调整再排除5972例，剩余9429例作分层分析。根据是否联用质子泵抑制剂（PPI），将出院应用氯吡格雷生存患者8942例分为氯吡格雷联合应用PPI组（4814例）和氯吡格雷未联合应用PPI组（4126例）；将出院应用替格瑞洛生存患者489例分为替格瑞洛联合应用PPI组（351例）和替格瑞洛未联合应用PPI组（138例）。Kaplan-Meier法分析显示氯吡格雷联合应用PPI组1年出血事件发生率明显高于氯吡格雷未联合应用PPI组，差异有统计学意义（P=0．004）；替格瑞洛联合应用PPI组1年出血事件发生率与替格瑞洛未联合应用PPI组比较，差异无统计学意义（P=0．573）。结论ACS患者PCI术后最常见的出血部位为消化道，PPI与替格瑞洛联合应用在胃肠道出血风险较高患者中适用。

关键词：急性冠状动脉综合征出血质子泵抑制剂氯吡格雷替格瑞洛

Notes,outline and divergence times of basidiomycota

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Fungal Diversity 2019年第6期99卷 105-367页

作者： Mao-Qiang He Rui-Lin Zhao Kevin D.Hyde Dominik begerow Martin Kemler Andrey Yurkov Eric H.C.McKenzie Olivier Raspe Makoto Kakishima Santiago Sanchez-Ramırez Else C.Vellinga Roy Halling Viktor Papp Ivan V.Zmitrovich bart buyck Damien Ertz Nalin N.Wijayawardene bao-Kai Cui Nathan Schoutteten Xin-Zhan Liu Tai-Hui Li Yi-Jian Yao Xin-Yu Zhu An-Qi Liu Guo-Jie Li Ming-Zhe Zhang Zhi-Lin Ling bin Cao Vladimir Antonin Teun boekhout bianca Denise barbosa da Silva Eske De Crop Cony Decock balint Dima Arun Kumar Dutta Jack W.Fell Jozsef Geml Masoomeh Ghobad-Nejhad Admir J.Giachini Tatiana b.Gibertoni sergio P.Gorjon Danny Haelewaters Shuang-Hui He brendan P.Hodkinson Egon Horak Tamotsu Hoshino Alfredo Justo Young Woon Lim Nelson Menolli Jr Armin Mesic Jean-Marc Moncalvo Gregory M.Mueller La szlo G.Nagy RHenrik Nilsson Machiel Noordeloos Jorinde Nuytinck Takamichi Orihara Cheewangkoon Ratchadawan Mario Rajchenberg Alexandre G.S.Silva-Filho Marcelo Aloisio Sulzbacher Zdenko Tkalcec Ricardo Valenzuela Annemieke Verbeken Alfredo Vizzini Felipe Wartchow Tie-Zheng Wei Michael Weib Chang-Lin Zhao Paul M.Kirk State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand College of Life Sciences University of Chinese Academy of SciencesHuairou DistrictBeijing 100408People’s Republic of China Ruhr-Universitat bochum AG GeobotanikND03UniversitatsstraBe 15044801 BochumGermany Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures InhoffenstraBe 7B38124 BrunswickGermany Manaaki Whenua-Landcare Research Private Bag 92170AucklandNew Zealand Research Department Meise Botanic GardenNieuwelaan 381860 MeiseBelgium Service General de l'Enseignement superieur et de la Recherche scientifique Federation Wallonie-BruxellesLavallee 11080 BrusselsBelgium University of Tsukuba TsukubaIbaraki 305-8572Japan Department of Ecology and Evolutionary biology University of Toronto25 Willcocks St.TorontoON M5S 3B2Canada berkeley USA Institute of Systematic botany The New York Botanical GardenBronxNY 10458-5126USA Department of botany Szent Istvan University1518 BudapestHungary Komarov botanical Institute Russian Academy of SciencesProfessor Popov st.2Saint PetersburgRussia 197376 Institut pour Systematique Ecologie biodiversite(ISYEb UMR 7205) Sorbonne universiteMuseum National d’Histoire Naturelle CP 39CNRSDepartement Origines et Evolution12 Rue Buffon75005 ParisFrance Institute of Microbiology Beijing Forestry UniversityBeijing 100083People’s Republic of China Department of biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Institute of MicrobiologyGuangzhou 510070People’s Republic of China Department of botany Moravian Mu

The basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the *** present work provides an overview of all validly published,currently used basidiomycete genera to date in a single *** outline of all genera of basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four *** provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence ***,three phylogenetic analyses with combined LSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,*** time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 *** study indicates that the divergence times of the subphyla in basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous *** this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 *** times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.

关键词： Classification Molecular clock Fungi Systematics Taxonomy