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MOOC在高等教育教学中的实践研究

洛阳师范学院学报 2018年第5期37卷 61-65页

作者：龚玉霞赛尔沃滕秀仪天津科技大学经济与管理学院天津300222

本文以在校大学生为调研对象,对大学生的自我学习能力、互相交流能力和展示能力、在线学习态度和对MOOC的认识和接受三个方面进行了实践研究.研究发现实施MOOC教育已经具备较好的基础,可以在一定范围内实施;实施MOOC教育仍然需要学校提... 详细信息

本文以在校大学生为调研对象,对大学生的自我学习能力、互相交流能力和展示能力、在线学习态度和对MOOC的认识和接受三个方面进行了实践研究.研究发现实施MOOC教育已经具备较好的基础,可以在一定范围内实施;实施MOOC教育仍然需要学校提供一定的学分约束;MOOC教育仍然要大力宣传和示范效应;对于MOOC教育,普遍结果是高年级学生接受度、认可度和自我管理能力高于低年级学生,男生优于女生,城市生源优于县乡生源.

关键词： MOOC 高等教育教学实践研究

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建筑之花

世界建筑导报 2020年第3期35卷 22-25页

作者：塞尔吉奥·皮罗内(摄影) 金吉妍无不详履露斋金孝晩建筑师事务所

一座立体小城,一条自由通道我们将这座建筑物视为一座立体小城,由四座独立的建筑物组成——咖啡厅、餐厅、办公室和住宅。通过外部楼梯享受空旷的空间,这是一条连接到现有城市的自由“通道”,带有一部忙碌着的垂直移动的红色电梯。

关键词：垂直移动咖啡厅建筑物小城立体

Update on the use of portable monitoring system for the diagnosis of sleep apnea in specific population

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World Journal of Respirology 2015年第1期5卷 17-27页

作者： erika Treptow Marcia Goncalves Oliveira Gustavo Antonio Moreira Sonia Togeiro Luiz eduardo Nery sergio Tufik Lia Bittencourt Departamento Psicobiologia Departamento de PsicobiologiaUniversidade Federal de Sao Paulo (UNIFESP) Disciplina de Pneumologia Departamento de MedicinaUniversidade Federal de Sao Paulo (UNIFESP)

The prevalence and severity of obstructive sleep apnea(OSA) is higher in specific population: children, elderly,obese and patients with pulmonary and cardiovascular diseases, compared to the general population. OSA is associated with greater morbidity and mortality in these patients. Although full-night polysomnography is still the gold standard diagnostic sleep study for OSA, it is a time consuming, expensive and technically demanding exam. Over the last few years, there is growing evidence on the use of portable monitors(PM) as an alternative for the diagnosis of OSA. These devices were developed specially for sleep evaluation at home, at a familiar environment, with easy selfapplication of monitoring, unattended. The use of PM is stablished for populations with high pre-test probability of OSA. However, there is a lack of studies on the use of PM in age extremes and patients with comorbidities. The purpose of this review is to present the studies that evaluated the use of PM in specific population, as well as to describe the advantages, limitations and applications of these devices in this particular group of patients. Although the total loss rate of recordings is variable in different studies, the agreement with fullnight polysomnography justifies the use of PM in this population.

关键词： Out-of-center sleep testing Obesity Home unattended portable monitoring elderly Children Portable monitoring Cardiovascular diseases Chronic obstructive pulmonary disease Polysomnography

长QT综合征的遗传学检测——一种临床高效基因分型方法的研发与验证

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美国医学会杂志（中文版） 2006年第6期25卷 323-328页

作者： Carlo Napolitano Silvia G. Priori Peter J. Schwartz Raffaella Bloise elena Ronchetti Janni Nastoli Georgia Bottelli Marina Cerrone sergio Leonardi 胥学伟（译）陆林（校）沈卫峰（校） Molecular Cardiology IRCCS Fondazione S. Maugeri Foundation Department of Cardiology University of Pavia IRCCS Policlinico S. Matteo Pavia Italy. 不详

背景：长QT综合征（long QT syndrome，LQTS）的严重程度及其对治疗的反应因致病遗传位点而异。因此，我们迫切需要建立一种能快速进行遗传学分析的方法。目的：对LQTS患者进行筛查，确定遗传学检测方法、突变类型及发生率。设计、患者... 详细信息

背景：长QT综合征（long QT syndrome，LQTS）的严重程度及其对治疗的反应因致病遗传位点而异。因此，我们迫切需要建立一种能快速进行遗传学分析的方法。目的：对LQTS患者进行筛查，确定遗传学检测方法、突变类型及发生率。设计、患者及地点：于1996年7月至2004年7月连续对430例患者进行遗传学检测，确定KCNQ1、KCNH2和SCN5A基因高频率突变密码子的检出是否可以成为一种新型、快速、高效基因分型策略。利用变性高效液相色谱法和DNA测序法筛查KCNQ1、KCNH2、SCN5A、KCNe1和KCNe2基因的全部编码区。确定突变的频率和类型，找出重复突变。另有一组连续75例先证者作为验证组，以便在前述LQTS人群中对检出重复突变的发生率进行前瞻性定量分析。主要观测指标：提出一种新型LQTS基因分型法。结果：在430例先证者（KCNQ149％、KCNH239％、SCA5A10％、KCNe11．7％、KCNe20．75％）中，有310例（72％）共检出235种不同的突变，其中138种为新的突变。58％的先证者在KCNQ1、KCNH2和SCA5A基因64种密码子携带非个人突变。在75例前瞻性先证队列和以往报告的LQTS队列中亦于这些密码子（52％）证实相似的突变发生率。结论：我们提出了一种改进LQTS遗传突变筛查效果的方法，这种新方法拓展了基因分型的范围，可使我们更好地对LQTS患者进行危险分层和治疗。

关键词：基因分型方法长QT综合征遗传学检测 SCN5A基因变性高效液相色谱法 KCNQ1 KCNH2 突变类型

临床怀疑深静脉血栓形成病人的压迫超声诊断:前瞻性队列研究

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英国医学杂志中文版 1998年第1期1卷 17-21页

作者： Alberto Cogo Anthonie W A Lensing Maria M W Koopman Franco Piovella sergio Siragusa Philip S Wells Sabina Villalta Harry R Bller Alexander G G Turpie Paolo Prandoni 冷希圣 lstituto di Semeiotica Medica University of Padua35128 PaduaItaly research fellow Centre for Vascular Medicine Academic Medical CentreH-2 1105 AZ AmsterdamNetherlands Senior researcher Pohclinico San Matteo Clinica Medica Seconda27100 Pavia Italy Senior researcher Pohclinico San Matteo Clinica Medica Seconda27100 Pavia Italy research fellow HGH McMaster Clinic Hamilton General Hospital Hamilton Ontario L8L 2X2 Canada HGH McMaster Clinic Hamilton General HospitalHamilton Ontario L8L 2X2 Canada Senior researcher lstituto di Semeiotica Medica University of Padua35128 PaduaItaly Senior researcher

目的:评价临床上怀疑为深静脉血栓形成但压迫超声显像所见正常病人不给予肝素治疗的安全性。设计:根据一种简化的程序来做压迫超声显像,超声显像的部位限于3处,即腹股沟部的股总静脉、腘静脉及胭静脉远端小腿静脉的分叉部位。初诊时超... 详细信息

目的:评价临床上怀疑为深静脉血栓形成但压迫超声显像所见正常病人不给予肝素治疗的安全性。设计:根据一种简化的程序来做压迫超声显像,超声显像的部位限于3处,即腹股沟部的股总静脉、腘静脉及胭静脉远端小腿静脉的分叉部位。初诊时超声显像为正常的病人1周后再重复检查1次。评价结果的标准:对于临床上怀疑为深静脉血栓形成的病人,凡是间隔1周两次超声显像均正常者则不予以肝素治疗,随访6个月,统计在这段时间内静脉血栓栓塞合并症的发生率。参加单位:四所大学附属医院的研究中心。结果:本研究共包括1702名病人,第一次检查发现400名血栓形成者,第二次检查又发现12名,因此用超声诊断方法在该1702名临床上怀疑为深静脉血栓形成的病人中确诊了412例,占24%。全组病人均获得随访,在两次 B 超检查之间,有1例发生了静脉血栓性栓塞的合并症,在6个月随访期间又有8例,所以累计发生率为0.7%(95%可信限为0.3%～1.2%),登门随访及补做检查的次数为平均每例0.8次。结论:对于临床上怀疑为深静脉血栓形成的病人,若连续两次压迫超声检查均为正常者,不给予肝素治疗是安全的。

关键词：深静脉血栓形成超声诊断超声显像重复检查胭静脉超声检查股总静脉小腿肌肉腹股沟部分叉部

Study of the Viability of Sargassum as a Substrate to Produce Biofuel

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Journal of environmental Science and engineering(A) 2022年第2期11卷 55-61页

作者： María Montes Alejandra Vásquez Jessica De la O Pedro García Guillermo Hermida Miguel Hernández sergio Zamora Department of environmental engineering Institute for EngineeringUniversity of VeracruzBoca del RioVer.94294Mexico Department Chemical engineering Faculty of Chemical SciencesUniversity of VeracruzBoca del RioVer.94294Mexico Department Dynamic of Systems Institute for EngineeringUniversity of VeracruzBoca del RioVer.94294Mexico Graduate Department Faculty of Construction Engineering and HabitatUniversity of VeracruzBoca del RíoVer.94294Mexico

Sargassum is an indicator of progressive pollution in the seas because it causes lack of light and lack of *** arrives in the Mexican Caribbean between the months of April and September,causing a bad smell that it has after its decomposition,a heavy load of heavy metals,as well as being an inconvenience for the inhabitants because it causes losses for tourism in that *** are several ways to take advantage of these algae and one of them is to generate biomass to obtain a *** objective of this study was to determine the viability of sargassum(two varieties)as a substrate to obtain biogas in anaerobic co-digestion with sludge from a WWTP(Wastewater Treatment Plant).Two forms of drying were also applied to the two varieties of *** was obtained that sargassum is a good component to co-digest because it does not destabilize the process and good biogas production is achieved.

关键词： Sargassum co-digestion biogas

Influence of breathing movements and Valsalva maneuver on vena caval dynamics

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World Journal of Radiology 2014年第10期6卷 833-839页

作者： Alicia Laborda sergio Sierre Mauro Malvè Ignacio De Blas Ignatios Ioakeim William T Kuo Miguel Angel De Gregorio Minimally Invasive Techniques Research Group Universidad de Zaragoza 50013 Zaragoza Spain Department of Mechanical engineering Energetics and Materials Universidad Pública de Navarra. Aragon Institute of Engineering Research31006 Pamplona Spain Department of Animal Pathology Faculty of Veterinary Universidad de Zaragoza 50013 Zaragoza Spain Division of Vascular and Interventional Radiology Stanford University Medical CenterCA 94305 United States

AIM: To study changes produced within the inferior vena cava(IVC) during respiratory movements and identify their possible clinical ***: This study included 100 patients(46 women; 54 men) over 18 years of age who required an abdominal computed tomography(CT) and central venous access. IVC cross-sectional areas were measured on CT scans at three levels, suprarenal(SR), juxtarenal(JR) and infrarenal(IR), during neutral breathing and again during the Valsalva maneuver. All patientswere instructed on how to perform a correct Valsalva maneuver. In order to reduce the total radiation dose in our patients, low-dose CT protocols were used in all patients. The venous blood pressure(systolic, diastolic and mean) was invasively measured at the same three levels with neutral breathing and the Valsalva maneuver during venous port implantation. From CT scans, threedimensional models of the IVC were constructed and a collapsibility index was calculated for each patient. These data were then correlated with venous pressures and cross-sectional ***: The mean patient age was 51.64 ± 12.01 years. The areas of the ellipse in neutral breathing were 394.49 ± 85.83(SR), 380.10 ± 74.55(JR), and 342.72 ± 49.77 mm2(IR), and 87.46 ± 18.35(SR), 92.64 ± 15.36(JR) and 70.05 ± 9.64 mm2(IR) during the Valsalva(P s ere was a correlation between areas in neutral breathing and in the Valsalva maneuver(P eas). Large areas decreased more than smaller areas. The collapsibility indices were 0.49 ± 0.06(SR), 0.50 ± 0.04(JR) and 0.50 ± 0.04(IR), with no significant differences in any region. Reconstructed three-dimensional models showed a flattening of the IVC during Valsalva, adopting an ellipsoid cross-sectional shape. The mean pressures with neutral breathing were 9.44 ± 1.78(SR), 9.40 ± 1.44(JR) and 8.84 ± 1.03 mmHg(IR), and 81.08 ± 21.82(SR), 79.88 ± 19.01(JR) and 74.04 ± 16.56 mmHg(IR) during Valsalva(P s ere was a negative correlatio

关键词： Inferior vena cava Morphology Respiratory movements Size Valsalva Venous hemodynamics

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街头的孤独之歌

摄影之友 2019年第10期 122-125页

作者：塞吉奥·加西亚·加瓦尔德李思瑾不详

城市之于每个人都有着不一样的魅力,这个游荡在巴塞罗那街头的摄影师将自己对周围的感知与希望糅合到了他极致的光影当中。街头摄影也包含了很多种类型。所有类型的照片都同样能吸引你的眼球,但我认为每张照片都必须有一个问题要回答,... 详细信息

城市之于每个人都有着不一样的魅力,这个游荡在巴塞罗那街头的摄影师将自己对周围的感知与希望糅合到了他极致的光影当中。街头摄影也包含了很多种类型。所有类型的照片都同样能吸引你的眼球,但我认为每张照片都必须有一个问题要回答,你在拍下这张照片时,是一些什么东西吸引着你,要问你自己这个问题。

关键词：巴塞罗那加瓦尔变焦镜头摄影师加西亚

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针灸治疗网球肘疗效的系统评价

针灸治疗网球肘疗效的系统评价