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Optimal microgrid planning for enhancing ancillary service provision

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Journal of Modern Power Systems and Clean Energy 2019年第4期7卷 862-875页

作者： sergio F.CONTRERAS Camilo A.CORTES Johanna M.A.MYRZIK Institute of Automation Technology University of BremenOtto-Hahn-Allee 1 NW1/M1050(70)28359 BremenGermany Department of Electrical and Electronics Engineering Universidad Nacional de ColombiaCarrera 30 Calle 45.Ciudad Universitaria Edificio 453Bogota′Colombia

Microgrids have presented themselves as an effective concept to guarantee a reliable,efficient and sustainable electricity delivery during the current transition era from passive to active distribution ***,microgrids could offer effective ancillary services(AS)to the power utility,although this will not be possible before the traditional planning and operation methodologies are ***,a probabilistic multi-objective microgrid planning(POMMP)methodology is proposed in this paper to contemplate the large number of variables,multiple objectives,and different constraints and uncertainties involved in the microgrid *** planning methodology is based on the optimal size and location of energy distributed resources with the goal of minimizing the mismatch power in islanded mode,while the residual power for AS provision and the investment and operation costs of the microgrid in grid-connected mode are maximized and minimized,*** that purpose,probabilistic models and a true multi-objective optimization problem are implemented in the *** methodology is tested in an adapted PG&E 69-bus distribution system and the non-dominated sorting genetic algorithmⅡ(NSGA-Ⅱ)optimization method and an analytic hierarchy process for decision-making are used to solve the optimization problem.

关键词： Microgrid Ancillary services(AS) Planning Multi-objective optimization Decision-making

High philopatry rates of Yellow-legged Gulls in the southeastern part of the Bay of Biscay

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Avian Research 2021年第3期12卷 391-398页

作者： sergio Delgado Alfredo Herrero Asier Aldalur Juan Arizaga Department of Ornithology Aranzadi Sciences SocietyZorroagagaina 1120014 DonostiaSpain

Background:Philopatry rate is one of the main factors shaping population dynamics in colonial *** rates of philopatry are linked to populations with high dispersal,while high rates are linked to populations with a very high spatial structure pattern(i.e.,metapopulations).The Cantabrian Yellow-legged Gull(Larus michahellis)population is considered to be resident,with relatively low dispersal *** estimations of its philopatry rates are however still ***,we aimed to estimate philopatry rates in the main Yellow-legged Gull colonies of the province of Gipuzkoa,in the southeastern part of the Bay of ***:We analysed 734 resightings,during the breeding season at the colonies of Getaria,Santa Clara and Ulia,relative to a total of 3245 individuals ringed at birth in these same colonies during a period of 13 *** data were analysed using Multi-State Recapture models in ***:After controlling survival and resighting probability,the average dispersal rate among colonies was 4%(±SD=2%)when individuals are immature,decreasing to 1±1%)for adult breeding gulls(i.e.,philopatry rate was 99%).Annual survival rates were assessed to be 0.27±0.02 for birds in their first year of life and 0.87±0.01 for older *** probability of observing immature birds in the colonies was 0.08±0.01,as compared to 0.21±0.02 in adult ***:We obtained evidence of extremely high local philopatry rates,clearly within the upper limit found in gulls.A high philopatry favour a speciation in these species who are vulnerable to obtain the main food source(land-fills and fishing discard)which are transforming under new ecological process.

关键词： Dispersal rates Metapopulation Philopatry Ringing Survival Seagulls

This work was supported by the European Research Council Advanced Grant(ETAP-742985 to *** J.F.)and by the Ministry of Science and Technology(grant 110-2636-B-005-001 to K.-J.L.).

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Plant Communications 2024年第1期5卷 130-147页

作者： Yu Zhang Yuan Fu Wenfei Xian Xiuli Li Yong Feng Fengjiao Bu Yan Shi Shiyu Chen Robin van Velzen Kai Battenberg Alison M.Berry Marco G.Salgado Hui Liu Tingshuang Yi Pascale Fournier Nicole Alloisio Petar Pujic Hasna Boubakri M.Eric Schranz Pierre-Marc Delaux Gane Ka-Shu Wong Valerie Hocher sergio Svistoonoff Hassen Gherbi Ertao Wang Wouter Kohlen Luis G.Wall Martin Parniske Katharina Pawlowski Philippe Normand Jeffrey J.Doyle Shifeng Cheng Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518124China Biosystematics Group Department of Plant SciencesWageningen University6708PB Wageningenthe Netherlands Department of Plant Sciences University of CaliforniaDavisDavisCA 95616USA Department of Ecology Environment and Plant SciencesStockholm University10691 StockholmSweden Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of SciencesLanhei RoadKunming 650201China Universite´de Lyon Universite´Lyon 1CNRSUMR5557Ecologie MicrobienneINRAUMR 141843 bd du 11 novembre 191869622 VilleurbanneFrance Laboratoire de Recherche en Sciences Ve´ge´tales(LRSV) Universite´de ToulouseCNRSUPS24 chemin de Borde RougeAuzevilleBP4261731326 Castanet TolosanFrance Department of Biological Sciences University of AlbertaEdmontonAB T6G 2E9Canada French National Research Institute for Sustainable Development(IRD) UMR LSTM(IRD/CIRAD/INRAe/Montpellier University/Supagro)-Campus International BaillarguetTA A-82/J34398 Montpellier Cedex 5France National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologySIBSChinese Academy of SciencesShanghaiChina Laboratory of Molecular Biology Department of Plant SciencesWageningen University6708PB Wageningenthe Netherlands Laboratory of Biochemistry Microbiology and Soil Biological InteractionsDepartment of Science and TechnologyNational University of QuilmesCONICETBernalArgentina Faculty of Biology GeneticsLMU MunichGroßhaderner Strasse 2-482152 MartinsriedGermany School of Integrative Plant Science Sections of Plant Biology and Plant Breeding&GeneticsCornell UniversityIthacaNY 14853USA State Key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of SciencesBeijing 100093China Univer

Plant root-nodule symbiosis(RNS)with mutualistic nitrogen-fixing bacteria is restricted to a single clade of angiosperms,the Nitrogen-Fixing Nodulation Clade(NFNC),and is best understood in the legume *** species share many commonalities,explained either by divergence from a common ancestor over 100 million years ago or by convergence following independent origins over that same time ***,comparative analyses of diverse nodulation syndromes can provide insights into constraints on nodulation—what must be acquired or cannot be lost for a functional symbiosis—and the latitude for Plant Communications Genomic landscape of nodulation variation in the ***,much remains to be learned about nodulation,especially outside of ***,we employed a large-scale phylogenomic analysis across 88 species,complemented by 151 RNA-seq libraries,to elucidate the evolution of *** phylogenomic analyses further emphasize the uniqueness of the transcription factor NIN as a master regulator of nodulation and identify key muta-tions that affect its function across the *** transcriptomic assessment revealed nodule-specific upregulated genes across diverse nodulating plants,while also identifying nodule-specific and nitrogen-response *** 70%of symbiosis-related genes are highly conserved in the four representative species,whereas defense-related and host-range restriction genes tend to be lineage *** study also identified over 900000 conserved non-coding elements(CNEs),over 300000 of which are unique to sampled NFNC ***-specific CNEs are enriched with the active H3K9ac mark and are correlated with accessible chromatin regions,thus representing a pool of candidate regula-tory elements for genes involved in ***,our results provide novel insights into the evolution of nodulation and lay a foundation for engineering of RNS traits in agriculturally important crops.

关键词： nitrogen-fixing root-nodule symbiosis two competing hypotheses phylogenomics phylotranscrip-tomics conserved non-coding elements convergence deep homology

PERTURBATION OF WAVELET AND GABOR FRAMES

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Analysis in Theory and Applications 2003年第3期19卷 238-254页

作者： Ivana Carrizo sergio Favier Instituto de Matemática Aplicada San Luis Universidad Nacional de San Luis Instituto de Matemática Aplicada San Luis Universidad Nacional de San Luis Av.Ejército de Los Andes 950.5700 San LuisArgentinaAv.Ejército de Los Andes 950.5700 San LuisArgentina

In this work two aspects of theory of frames are presented: a side necessary condition on irregular wavelet frames is obtained, another perturbation of wavelet and Gabor frames is considered. Specifically, we present the results obtained on frame stability when one disturbs the mother of wavelet frame, or the parameter of dilatation, and in Gabor frames when the generating function or the parameter of translation are perturbed. In all cases we work without demanding compactness of the support, neither on the generating function, nor on its Fourier transform.

关键词： Riesz basis Gabor frame wavelet frame perturbation

Reversible acetylation regulates vascular endothelial growth factor receptor-2 activity

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Journal of Molecular Cell Biology 2014年第2期8卷 116-127页

作者： Annalisa Zecchin Lucia Pattarini Maria Ines Gutierrez Miguel Mano Antonello Mai sergio Valente Mike P. Myers sergio Pantano Mauro Giacca Molecular Medicine Laboratory International Centre for Genetic Engineering and Biotechnology (ICGEB) Trieste Italy Istituto Pasteur-Fondazione cenci-Bolognetti Dipartimento di Chimica e Tecnologie del Farmaco Sapienza Universita' di Roma Rome Italy Protein Networks Laboratory International Centre for Genetic Engineering and Biotechno[ogy (ICGEB) Trieste Italy Biomolecular Simulations Group Institut Pasteur de Montevideo' Montevideo Uruguay U932 Immunity and Cancer Integrative Biology of Human Dendritic Cells and T Cells Laboratory Institute Curie Paris France

The tyrosine kinase receptor vascular endothelial growth factor receptor 2 （VEG FR2） is a key regulator of angiogenesis. Here we show that VEGFR2 is acetylated in endothelial cells both at four lysine residues forming a dense cluster in the kinase insert domain and at a single lysine located in the receptor activation loop. These modifications are under dynamic control of the acetyltransferase p300 and two deacetyiases HDAC5 and HDAC6. We demonstrate that VEGFR2 acetylation essentially regulates receptor phosphorylation. In par- ticular, VEGFR2 acetylation significantly alters the kinetics of receptor phosphorylation after ligand binding, allowing receptor phos- phoryiation and intraceUular signaling upon proLonged stimulation with VEGF. Molecular dynamics simulations indicate that acetylation of the lysine in the activation loop contributes to the transition to an open active state, in which tyrosine phosphorylation is favored by better exposure of the kinase target residues. These findings indicate that post-translational modification by acetyiation is a critical mechanism that directLy affects VEGFR2 function.

关键词： acetylation angiogenesis p300 phosphorylation vascular endothelial growth factor

Thermal ablation in colorectal liver metastases: Lack of evidence or lack of capability to prove the evidence?

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World Journal of Gastroenterology 2016年第13期22卷 3511-3515页

作者： sergio Sartori Paola Tombesi Francesca Di Vece Section of Interventional Ultrasound St Anna Hospital

Many studies suggest that combined multimodality treatments including ablative therapies may achieve better outcomes than systemic chemotherapy alone in patients with colorectal liver metastases. Nevertheless, ablative therapies are not yet considered as effective options because their efficacy has never been proved by randomized controlled trials (RCT). However, there are in literature no trials that failed in demonstrating the effectiveness of ablative treatments: what are lacking, are the trials. All the attempts to organize phase III studies on this topic failed as a result of non accrual. Just one prospective RCT comparing radiofrequency ablation combined with systemic chemotherapy vs chemotherapy alone has been published. It was designed as a phase III study, but it was closed early because of slow accrual, and was downscaled to phase II study, with the consequent limits in drawing definite conclusions on the benefit of combined treatment. However, the combination treatment met the primary end point of the study and obtained a significantly higher 3-year progression-free survival than systemic chemotherapy alone. It is very unlikely that ultimate efficacy of ablation treatments will ever be tested again, and the best available evidence points toward a benefit for the combination strategy using ablative treatments and chemotherapy.

关键词： Liver metastases Colorectal cancer Thermal ablation Radiofrequency ablation Microwave ablation Laser ablation Systemic chemotherapy

Differences in physiological integration between invasive and noninvasive introduced clonal species of Carpobrotus

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Journal of Plant Ecology 2019年第6期12卷 972-981页

作者： sergio R.Roiloa Peter Alpert Rodolfo Barreiro BioCost Group Biology DepartmentUniversidade da CoruñaA CoruñaSpain Biology Department University of MassachusettsAmherstMA 01003USA

Aims Clonal growth is associated with invasiveness in introduced plant species,but few studies have compared invasive and noninvasive introduced clonal species to investigate which clonal traits may underlie *** test the hypothesis that greater capacity to increase clonal growth via physiological integration of connected ramets increases invasiveness in clonal plants,we compared the effects of severing connections on accumulation of mass in the two species of the creeping,succulent,perennial,herbaceous genus Carpobrotus that have been introduced on sand dunes along the Pacific Coast of northern California,the highly invasive species Carpobrotus edulis and the co-occurring,noninvasive species Carpobrotus *** Pairs of ramets from four mixed populations of the species from California were grown in a common garden for 3 months with and without severing the stem connecting the *** simulate the effect of clones on soils in natural populations,the older ramet was grown in sand amended with potting compost and the younger in sand *** Findings Severance decreased net growth in mass by~60%in *** and~100%in ***,due mainly to the negative effect of severance on the shoot mass of the younger ramet within a *** to the hypothesis,this suggests that physiological integration increases growth more in the less invasive ***,severance also decreased allocation of mass to roots in the older ramet and increased it in the younger ramet in a pair,and the effect on the younger ramet was about twice as great in *** as in *** indicates that the more invasive species shows greater phenotypic plasticity in response to physiological integration,in particular greater capacity for division of *** could contribute to greater long-term growth and suggests that the division of labor may be a trait that underlies the association between clonal growth and invasiveness in plants.

关键词： biomass allocation Carpobrotus clonal growth physiological integration plant invasions

Root symbionts： Powerful drivers of plant above- and belowground indirect defenses

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Insect Science 2017年第6期24卷 947-960页

作者： sergio Rasmann Alison Bennett Arjen Biere Alison Karley Emilio Guerrieri Institute of Biology University of Neuchatel Neuchatel Switzerland Department of Ecological Sciences James Hutton Institute Dundee UK Netherlands Institute of Ecology Wageningen the Netherlands Institute for Sustainable Plant Protection National Research Council of Italy Portici Italy

Soil microbial mutualists of plants, including mycorrhizal ftmgi, non- mycorrhizal fungi and plant growth promoting rhizobacteria, have been typically characterized for increasing nutrient acquisition and plant growth. More recently, soil microbes have also been shown to increase direct plant defense against above- and below- ground herbivores. Plants, however, do not only rely on direct defenses when attacked, but they can also recruit pest antagonists such as predators and parasitoids, both above and belowground, mainly via the release of volatile organic compounds （i.e., indirect defenses）. In this review, we illustrate the main features and effects of soil microbial mutualists of plants on plant indirect defenses and discuss possible applications within the framework of sustainable crop protection against root- and shoot-feeding arthropod pests. We indicate the main knowledge gaps and the future challenges to be addressed in the study and application of these rnultifaceted interactions.

关键词： arbuscular mycorrhizal fungi crop protection entomopathogenic nematodes plant growth promoting rhizobacteria Trichoderma

Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease

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World Journal of Gastroenterology 2006年第27期12卷 4369-4376页

作者： Nimer Assy Masha Grozovski Ilana Bersudsky sergio Szvalb Osamah Hussein Liver Unit Sieff HospitalSafedIsrael and Technion InstituteFaculty of MedicineHaifaIsrael Department of Internal Medicine ASieff HospitalSafedIsrael Ort Braude College KarmielIsrael Department of Pathology Sieff HospitalSafedIsrael Department of Internal Medicine A Sieff HospitalSafedIsrael

AIM： To assess whether treatment with insulinsensitizing agents （ISAs） in combination with ezetimibe and valsartan have greater effect on hepatic fat content and lipid peroxidation compared to monotherapy in the methionine choline-deficient diet （MCDD） rat model of non-alcoholic fatty liver disease （NAFLD）. METHODS： Rats （n = 6 per group） were treated with different drugs, including MCDD only, MCDD diet with either metformin （200 mg/kg）, rosiglitazone （3 mg/kg）, metformin plus rosiglitazone （M＋R）, ezetimibe （2 mg/ kg）, valsartan （2 mg/kg）, or combination of all drugs for a total of 15 wk. Liver histology, lipids, parameters of oxidative stress and TNF-alpha were measured. RESULTS： Fatty liver （FL） rats demonstrated severe hepatic fatty infiltration （〉 91% fat）, with an increase in hepatic TG （＋1263%, P 〈 0.001）, hepatic cholesterol （＋245%, P 〈 0.03）, hepatic MDA levels （＋225%, P 〈 0.001）, serum TNF-alpha （17.8 ＋ 10 vs 7.8 ＋ 0.0, P 〈 0.001）, but a decrease in hepatic alpha tocopherol （-74%, P 〈 0.001） as compared to the control rats. Combination therapy with all drugs produced a significant decrease in liver steatosis （-54%）, hepatic TG （-64%）, hepatic cholesterol （-31%） and hepatic MDA （-70%）, but increased hepatic alpha tocopherol （＋443%） as compared to FL rats. Combination therapy with ISA alone produced a smaller decrease in liver steatosis （-32% vs -54%, P 〈 0.001） and in hepatic MDA levels （-55% vs -70%, P 〈 0.01）, but a similar decrease in hepatic lipids when compared with the all drugs combination. TNF-alpha levels decreased significantly in all treatment groups except in ISA group. CONCLUSION： Combination therapies have a greater effect on liver fat content as compared to monotherapy. Rosiglitazone appears to improve hepatic steatosis to a greater extent than metformin.

关键词： Fatty liver Rosiglitazone Metformin Ezetimibe Valsartan Methionine choline-deficient diet Insulin resistance