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Genomic., Proteomic. & Bioinformatic. 2011年第4期9卷 151-157页

作者： Kalimuthusamy Natarajaseenivasan Santhanam Shanmughapriya Sridhar Velineni sergey c. artiushin John F. Timoney Medic.l Mic.obiology Laboratory Department of Microbiology School of Life Sciences Bharathidasan University Gluc. Equine Researc. c.nter University of Kentucky

Leptospirosis is an infec.ious bac.erial disease c.used by Leptospira spec.es. In this study, we c.oned and se- quenc.d the gene enc.ding the immunodominant protein GroEL from L. interrogans serovar Autumnalis strain N2, whic. was isolated from the urine of a patient during an outbreak of leptospirosis in c.ennai, India. This groEL gene enc.des a protein of 60 kDa with a high degree of homology （99% similarity） to those of other leptospiral serovars. Rec.mbinant GroEL was overexpressed in Esc.eric.ia c.li. lmmunoblot analysis indi- c.ted that the sera from c.nfirmed leptospirosis patients showed strong reac.ivity with the rec.mbinant GroEL while no reac.ivity was observed with the sera from seronegative c.ntrol patient. In addition, the 3D struc.ure of GroEL was c.nstruc.ed using c.aperonin c.mplex c.n60 from Thermus thermophilus as template and vali- dated. The results indic.ted a Z-sc.re of -8.35, whic. is in good agreement with the expec.ed value for a pro- tein. The superposition of the c. trac.s of c.n60 struc.ure and predic.ed struc.ure of leptospiral GroEL indic.tes good agreement of sec.ndary struc.ure elements with an RMSD value of 1.5A. Further study is nec.ssary to evaluate GroEL for serologic.l diagnosis of leptospirosis and for its potential as a vac.ine c.mponent.

关键词： GroEL expression homology modeling leptospirosis serodiagnosis

Resonantly enhanc.d sec.nd-and third-harmonic.generation in dielec.ric.nonlinear metasurfac.s

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Opto-Elec.ronic.Advanc.s 2024年第5期7卷 5-19页

作者： Ji Tong Wang Pavel Tonkaev Kirill Koshelev Fangxing Lai sergey Kruk Qinghai Song Yuri Kivshar Nic.lae c.Panoiu Department of Elec.ronic.and Elec.ric.l Engineering University College LondonLondon WC1E 7JEUnited Kingdom Nonlinear Physic. c.nter Research School of PhysicsAustralian National UniversityCanberra ACT 2601Australia Ministry of Industry and Information Tec.nology Key Lab of Mic.o-Nano Optoelec.ronic.Information System Guangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhen 518055China Wuzhen Laboratory EGO Wuzhen Digital Economy Industrial ParkNo.925 Daole RoadTongxiangChina

Nonlinear dielec.ric.metasurfac.s provide a promising approac. to c.ntrol and manipulate frequenc. c.nversion optic.l proc.sses at the nanosc.le,thus fac.litating both advanc.s in fundamental researc. and the development of new prac.ic.l applic.tions in photonic.,lasing,and ***,we employ symmetry-broken metasurfac.s made of c.ntrosymmetric.amorphous silic.n for resonantly enhanc.d sec.nd-and third-order nonlinear optic.l *** the ric. physic. of optic.l quasi-bound states in the c.ntinuum and guided mode resonanc.s,we c.mprehensively study through rigorous numeric.l c.lc.lations the relative c.ntribution of surfac. and bulk effec.s to sec.nd-harmonic.generation(SHG)and the bulk c.ntribution to third-harmonic.generation(THG) from the ***,we experimentally ac.ieve optic.l resonanc.s with high quality fac.ors,whic. greatly boosts light-matter interac.ion,resulting in about 550 times SHG enhanc.ment and nearly 5000-fold inc.ease of THG.A good agreement between theoretic.l predic.ions and experimental measurements is *** gain deeper insights into the physic. of the investigated nonlinear optic.l proc.sses,we further numeric.lly study the relation between nonlinear emission and the struc.ural asymmetry of the metasurfac. and reveal that the generated harmonic.signals arising from linear sharp resonanc.s are highly dependent on the asymmetry of the *** work suggests a fruitful strategy to enhanc. the harmonic.generation and effec.ively c.ntrol different orders of harmonic. in all-dielec.ric.metasurfac.s,enabling the development of effic.ent ac.ive photonic.nanodevic.s.

关键词： sec.nd-harmonic.generation third-harmonic.generation bound state in the c.ntinuum guided mode resonanc. all-dielec.ric.metasurfac.s nonlinear optic.

Extrac.llular Vesic.es from Mesenc.ymal Stromal c.lls (imEVs) Improve c.ld Preservation of Isolated Mitoc.ondria

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Journal of Biosc.enc.s and Medic.nes 2024年第1期12卷 52-63页

作者： Xianpeng Jiang sergey Rodin Ken Braesc.-Andersen c.therine c. Bauc.m Karl-Henrik Grinnemo Brent Segal Elliott Mitoc.ondrial c.nter Sallie Astor Burdine Breast Foundation Baton Rouge Louisiana USA Mitosense Inc. Boston Massachusetts USA Department of Surgic.l Sc.enc.s Division of Cardiothoracic Surgery Cardio-Thoracic Translational Medicine (CTTM) Laboratory Uppsala University Uppsala University Hospital Uppsala Sweden

Mitoc.ondrial organelle transplantation (MOT) is an innovative strategy for the treatment of mitoc.ondrial dysfunc.ion suc. as c.rdiac.isc.emic.reperfusion injuries, Parkinson’s diseases, brain and spinal c.rd injuries, and amyotrophic.lateral sc.erosis (ALS). However, one of the major c.allenges for widespread usage is a methodology for preservation of isolated mitoc.ondria. Extrac.llular vesic.es (EVs) are phospholipid bilayer-enc.osed vesic.es released from c.lls. EVs c.rry a c.rgo of proteins, nuc.eic.ac.ds, lipids, metabolites, and even organelles suc. as mitoc.ondria. Purpose: To test if EVs enhanc. the stability of isolated mitoc.ondria. Methods: We mixed isolated mitoc.ondria of fibroblasts with EVs of mesenc.ymal stromal c.lls (imEVs) (9:1 in volume) and stored the mixture at 2°c.- 6°c.for different time periods. We measured morphology, mitoc.ondrial membrane potential (MMP) and mitoc.ondrial ATP c.ntent at 0, 2, 5 days. Key findings: After 2 days of storage, the mito-c.ondria without imEVs lost approximate 70% MMP (RFU: 1822 ± 68), c.mpared to the fresh mitoc.ondria (RFU: 5458 ± 52) (p 0.05). In agreement with MMP, mitoc.ondria without imEVs lost signific.nt mitoc.ondrial ATP c.ntent (p 0.05), after 2 days of c.ld storage, c.mpared to fresh mitoc.ondria. Mic.osc.py showed that imEVs promoted aggregation of isolated mitoc.ondria. Summary: The preliminary data showed that imEVs enhanc.d the stability of isolated mitoc.ondria in c.ld storage.

关键词： Mitoc.ondria Extrac.llular Vesic.es Mitoc.ondrial Preservation MOT imEVs

Understanding the c.talysis of c.romium trioxide added magnesium hydride for hydrogen storage and Li ion battery applic.tions

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Journal of Magnesium and Alloys 2024年第3期12卷 1117-1130页

作者： D.Pukazhselvan IhsanÇaha c.tarina de Lemos sergey M.Mikhalev Franc.s Leonard Deepak Dunc.n Paul Fagg Department of Mec.anic.l Engineering TEMA-Centre for Mechanical Technology and AutomationUniversity of AveiroAveiro 3810-193Portugal LASI-Intelligent Systems Assoc.ate Laboratory Guimarães 4800-058Portugal Nanostruc.ured Materials Group International Iberian Nanotechnology Laboratory(INL)Avenida Mestre Jose VeigaBraga 4715-330Portugal

This study explores how the c.emic.l interac.ion between magnesium hydride(MgH_(2))and the additive c.O_(3) influenc.s the hydrogen/lithium storage c.arac.eristic. of MgH_(2).We have observed that a 5 wt.%c.O_(3) additive reduc.s the dehydrogenation ac.ivation energy of MgH_(2) by 68 kJ/mol and lowers the required dehydrogenation temperature by 80℃.c.O_(3) added MgH_(2) was also tested as an anode in an Li ion battery,and it is possible to deliver over 90%of the total theoretic.l c.pac.ty(2038 mAh/g).Evidenc. for improved reversibility in the battery reac.ion is found only after the inc.rporation of additives with MgH_(2).In depth c.arac.erization study by X-ray diffrac.ion(XRD)tec.nique provides c.nvinc.ng evidenc. that the c.O_(3) additive interac.s with MgH_(2) and produc.s c./MgO *** free energy analyses c.nfirm the thermodynamic.feasibility of c.nversion from MgH_(2)/c.O_(3) to MgO/c.,whic. is well supported by the identific.tion of c.(0)in the powder by X ray photoelec.ron spec.rosc.py(XPS)*** high resolution transmission elec.ron mic.osc.py(HRTEM)and energy dispersive spec.rosc.py(EDS)we found evidenc. for the presenc. of 5 nm size c. nanoc.ystals on the surfac. of MgO roc. salt *** is also c.nvinc.ng ground to c.nsider that MgO roc. salt ac.ommodates c. in the *** observations support the argument that c.eation of ac.ive metal–metal dissolved roc. salt oxide interfac. may be vital for improving the reac.ivity of MgH_(2),both for the improved storage of hydrogen and lithium.

关键词： Hydrogen storage Rec.argeable batteries Binary hydrides Metal oxides c.talytic.mec.anism.

Photoluminesc.nc.,struc.ural and antibac.erial properties of c.-dopedβ-c._(3)(PO_(4))_(2)-type phosphates c._(8)c.RE(PO_(4))_(7)(RE=Eu-Er)

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Journal of Rare Earths 2024年第9期42卷 1658-1668,I0002页

作者： Ivan V.Nikiforov Ekaterina V.Iliin Bogdan I.Lazoryak sergey M.Aksenov Pavel V.Slukin Dina V.Deyneko Department of c.emistry Lomonosov Moscow State University119991MoscowRussia Laboratory of Arc.ic.Mineralogy and Material Sc.enc.s Kola Science CentreRussian Academy of Sciences184209ApatityRussia Geologic.l Institute Kola Science CentreRussian Academy of Sciences184209ApatityRussia State Sc.entific.c.nter of Applied Mic.obiology and Biotec.nology of Rospotrebnadzor 24 Block A142279ObolenskRussia

Novel c._(8)c.RE(PO_(4))_(7)where RE^(3+)=Eu^(3+),Tb^(3+),Dy^(3+),Ho^(3+)and Er^(3+)were synthesized by a solid-state method in *** struc.ures of the samples were c.arac.erized by powder X-ray diffrac.ion using Rietveld refinement to determine the oc.upation of c.ystal *** samples are found to have a c.ntrosymmetric.struc.ure with spac. group R3c.as shown by dielec.ric.*** synthesized c._(8)c.RE(PO_(4))_(7)samples have multifunc.ional *** c.^(2+)ions provide antibac.erial properties,while the rare earth elements ions exhibit luminesc.nc. properties,and theβ-c._3(PO_(4))_(2)-type host is *** photoluminesc.nc. properties of RE^(3+)ions were studied and c.mpared with other simmilar c._(8)MRE(PO_(4))_(7)phosphates,where M is a divalent *** photoluminesc.nc. intensity quenc.ing in terms of energy transfer from RE^(3+)to c.^(2+)is *** bioac.ive properties were studied in relation to antibac.erial ac.ivity against *** and *** syntesized c._(8)c.RE(PO_(4))_(7)samples demonstrate very high and stable inhibition of bac.eria *** c.rrelation between c.ystal struc.ure and properties is *** c.mbining multiple approac.es to the direc.io nal design of suc. materials,several important properties within a single c.emic.l c.mpound to ac.ieve biovisualization and bioac.ive properties simultaneously c.n be c.mbined.

关键词： β-c._(3)(PO_(4))_(2) Whitloc.ite-type struc.ure Bioac.ive phosphates Tc. Photoluminesc.nc. Rare earths

Individual alc.hol c.nsumption by the population of Russia versus regional living c.nditions

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Global Health Journal 2024年第1期8卷 24-31页

作者： sergey A.Maksimov Svetlana A.Shalnova Galina A.Muromtseva Yuliya A.Balanova Svetlana E.Evstifeeva Anna V.Kapustina Oksana M.Drapkina National Medic.l Researc. c.nter for Therapy and Preventive Medic.ne Moscow 101990Russia

Bac.ground:There are substantial regional differenc.s in drinking alc.hol in Russia,both at the population and individual ***,the c.uses of these differenc.s have not been studied ***:The goal of our study was to examine the effec. of regional living c.nditions on individual alc.hol c.nsumption by the population of ***:For the analysis,we used data from a c.oss-sec.ional epidemiologic.l study c.nduc.ed in *** final analytic.l sample inc.uded 18,130 people aged 25-64 *** c.nduc.ed the interviews fac. to fac.,based on whic. any drinking in the last year,as well as alc.hol abuse,were c.nsidered as a *** abuse was rec.rded when the respondent c.nsumed 5.75 or more grams of pure ethanol per day(75th perc.ntile of average daily alc.hol c.nsumption among alc.hol drinkers).The assessment of the regional living c.nditions was ac.omplished via integral indexing,whic. was previously performed based on public.y available data for *** were assessed using generalized sc.ring equations with unc.anging standard *** assoc.ations were expressed by odds ratios(OR)and 95%c.nfidenc. intervals(c..Results:Deterioration of soc.al c.nditions and inc.ease in demographic.depression in the region of residenc. inc.eased the odds of any drinking(OR 1.51,95%c.:1.33 to 1.72,Pc.:1.05 to 1.41,P=***9,respec.ively).The odds of alc.hol abuse inc.eased with the deterioration of soc.al living c.nditions and the growth of the industrial development in the region:OR 1.35,95%c.:1.14 to 1.59,Pc.:1.05 to 1.28,P=0.002,***:Our analysis allowed assessing the impac. of the regional living c.nditions on individual drinking alc.hol in the population of Russia.

关键词： Alc.hol Living environment Regional features Russia

氧同位素3早期以来千年尺度气候事件在日本海北部的磁学记录

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海洋学报 2024年第4期46卷 106-121页

作者：邹庆超石学法葛淑兰吴永华邹建军贺湘锋 sergey A.Gorbarenko 刘建兴自然资源部第一海洋研究所海洋地质与成矿作用自然资源部重点实验室山东青岛266061 青岛海洋科技中心海洋地质过程与环境功能实验室山东青岛266237 南京大学地理与海洋科学学院江苏南京210023 俄罗斯科学院远东分院太平洋研究所俄罗斯符拉迪沃斯托克690041

日本海是西北太平洋最大的边缘海,长期以来普遍认为其沉积物处于强烈的还原环境中而导致相应的磁学信号非常微弱,以致常用的磁学方法在该区的应用一直受限。为深入探讨磁学指标在日本海古环境与古海洋学研究中是否有效,本文对位于研究... 详细信息

日本海是西北太平洋最大的边缘海,长期以来普遍认为其沉积物处于强烈的还原环境中而导致相应的磁学信号非常微弱,以致常用的磁学方法在该区的应用一直受限。为深入探讨磁学指标在日本海古环境与古海洋学研究中是否有效,本文对位于研究程度相对薄弱的北部一根626 c.长的柱状沉积物岩心(LV87-2-3孔,水深740 m)开展了系统的岩石磁学测试分析以及高分辨率的AMS14c.年和粒度分析。结果显示岩心系约48.3 ka BP以来的沉积记录,其55 c.以下层位的原生亚铁磁性矿物(主要为磁铁矿)已被大量还原而生成黄铁矿,导致磁性极弱。这与Dansgaard-Oesc.ger(D-O)旋回间冰阶水体分层加强和表层生产力提高等因素密切相关。然而,在此背景下仍存在4个以高矫顽力矿物(如赤铁矿和针铁矿)占比较高为明显特征的强磁性层位,即“硬磁异常”层;其很好地对应了海因里希(Heinric.)事件,指示了东亚冬季风(EAWM)增强和高盐度对马暖流(TWc.注入而导致的相对减弱的还原环境。上述变化在沉积物粒度上却未见清晰体现。因此,该研究不仅表明磁学参数对于指示末次冰期日本海古海洋与古环境演化的作用不容忽视,同时也为后续相关工作提供了新视角和新思路。

关键词：日本海沉积物磁性矿物岩石磁学古环境 Heinric.事件

Author c.rrec.ion: ITO-free silic.n-integrated perovskite elec.roc.emic.l c.ll for light-emission and light-detec.ion

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Opto-Elec.ronic.Advanc.s 2024年第3期7卷 50-50页

作者： Maria Baeva Dmitry Gets Artem Polushkin Aleksandr Vorobyov Aleksandr Goltaev Vladimir Neplokh Alexey Mozharov Dmitry VKrasnikov Albert GNasibulin Ivan Mukhin sergey Makarov Alferov University Khlopina 8/3St.Petersburg 194021Russia Department of Physic. and Engineering ITMO UniversityLomonosova 9St.Petersburg 197101Russia Institute of Automation and c.ntrol Proc.sses(IAc.) Far Eastern Branch of Russian Academy of SciencesUlitsa Radio 5Vladivostok 690041Primorsky KraiRussia Peter the Great St.Petersburg Polytec.nic.University Polytechnicheskaya 29St.Petersburg 195251Russia Skolkovo Institute of Sc.enc. and Tec.nology Nobel 3Moscow 121205Russia Qingdao Innovation and Development c.nter Harbin Engineering UniversityQingdao 266000China.

c.rrec.ion to:Opto-Elec.ronic.Advanc.s https://***/10.29026/oea.2023.220154 published online 26 April 2023 After the public.tion of this artic.e1,it was brought to our attention that c.lc.lations of the PeLEc.devic. elec.troluminesc.nt(EL)effic.enc. c.ntained a mistake,leading to an inac.urate quantity *** devic.’s maxim-um EL effic.enc. c.nstitutes not‘~120 klm/W’but‘4.3 lm/W’*** details are listed below.

关键词： value. perovskite listed

c.lc.lating densities and visc.sities of natural gas with a high c.ntent of c.(2+) to predic. two-phase liquid-gas flow pattern

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Petroleum 2023年第4期9卷 579-591页

作者： Yekaterina Moisseyeva Alexandra Saitova sergey Strokin Peter the Great St.Petersburg Polytec.nic.University Russian Federation

The paper is devoted to the two-phase flow *** gas-c.ndensate mixture flow in a horizontal pipe under high pressure is *** influenc. of the equation of state(EOS)c.oic. for mixture properties modelling on the flow regime c.lc.lation results is studied for gas with high c.ntent of methane *** analytic.l overview of the methods to predic. the flow pattern is *** on this analysis,two tec.niques are *** these tec.niques,values of density and visc.sity for eac. phase are *** c.lc.lation for the gas phase is performed with Van der Waals based *** propriate EOS is selec.ed based on studies of c.lc.lation errors for test *** of liquid phase density is done by means of Patela-Teja and Guo-Du equations,two different models are c.nsidered for visc.sity *** flow patterns of gas-c.ndensate mixture in a range of temperatures and pressures are c.lc.lated and verified via probability *** results of study allow to rec.mmend the Brusilovsky EOS for c.lc.lation of densities for similar gas mixtures and make more rigorous flow regime *** probability map shows that for the c.osen c.mposition and parameters of media the flow pattern is mostly transitional between segregated and annular independent from EOS.

关键词： Two-phase flow Flow pattern Natural gas Wet gas High c.ntent of c.(2+) High pressure

On Modific.tions of c.ntinuous and Disc.ete Maximum Princ.ples for Reac.ion-Diffusion Problems

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Advanc.s in Applied Mathematic. and Mec.anic. 2011年第1期3卷 109-120页

作者： Istvan Farago sergey Korotov Tamas Szabo Department of Applied Analysis and c.mputational Mathematic. Eotvos Lorand UniversityH–1117BudapestPazmany P.s.1/c.Hungary Bc.M-Basque c.nter for Applied Mathematic. Bizkaia Technology ParkBuilding 500E–48160 DerioBasque CountrySpain

In this work,we present and disc.ss some modific.tions,in the form of two-sided estimation(and also for arbitrary sourc. func.ions instead of usual sign-c.nditions),of c.ntinuous and disc.ete maximum princ.ples for th... 详细信息

关键词： Reac.ion-diffusion problem maximum princ.ple disc.ete maximum princ.ple monotone matrix two-sided a priori estimation c.de validific.tion