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Radionuclides and mercury in the salt lakes of the Crimea

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Chinese Journal of Oceanology and Limnology 2015年第6期33卷 1413-1425页

作者： Natalya MIRZOYEVA Larisa GULINA sergey GULIN Olga PLOTITSINA Alexandra STETSUK Svetlana ARKHIPOVA Nina KORKISHKO Oleg EREMIN Institute of Biology of the Southern Seas (IBSS)

^99Sr concentrations, resulting from the Chernobyl NPP accident, were determined in the salt lakes of the Crimea （Lakes Kiyatskoe, Kirleutskoe, Kizil-Yar, Bakalskoe and Donuzlav）, together with the redistribution between the components of the ecosystems. The content of mercury in the waters of the studied reservoirs was also established. Vertical distributions of natural radionuclide activities （^238U, ^232Th, ^226Ra, ^210pb, ^40K） and anthropogenic ^137Cs concentrations （as radiotracers） were determined in the bottom sediments of the Koyashskoe salt lake （located in the south-eastern Crimea） to evaluate the long- term dynamics and biogeochemical processes. Radiochemical and chemical analysis was undertaken and radiotracer and statistical methods were applied to the analytical data. The highest concentrations of ^99Sr in the water of Lake Kiyatskoe （350.5 and 98.0 Bq/m^3） and Lake Kirleutskoe （121.3 Bq/m^3） were due to the discharge of the Dnieper water from the North-Crimean Canal. The high content of mercury in Lake Kiyatskoe （363.2 ng/L） and in seawater near Lake Kizil-Yar （364 ng/L） exceeded the maximum permissible concentration （3.5 times the maximum）. Natural radionuclides provide the main contribution to the total radioactivity （artificial and natural combined） in the bottom sediments of Lake Koyashskoe. The significant concentration of ^210pb in the upper layer of bottom sediments of the lake indicates an active inflow of its parent radionuclide-gaseous ^222Rn from the lower layers of the bottom sediment. The average sedimentation rates in Lake Koyashskoe, determined using ^210pb and ^137Cs data, were 0.117 and 0.109 cm per year, respectively.

关键词： Crimea salt lakes Black Sea Chernobyl NPP accident radionuclides mercury ecological impact

Selection of phages and conditions for the safe phage therapy against Pseudomonas aeruginosa infections

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Virologica Sinica 2015年第1期30卷 33-44页

作者： Victor Krylov Olga Shaburova Elena Pleteneva sergey Krylov Alla Kaplan Maria Burkaltseva Olga Polygach Elena Chesnokova I.I. Mechnikov Research Institute for Vaccines & Sera RAMS Moscow 105064 Russian

The emergence of multidrug-resistant bacterial pathogens forced us to consider the phage therapy as one of the possible alternative approaches to treatment. The purpose of this paper is to consider the conditions for the safe, long-term use of phage therapy against various infections caused by Pseudomonas aeruginosa. We describe the selection of the most suitable phages, their most effective combinations and some approaches for the rapid recognition of phages unsuitable for use in therapy. The benefi ts and disadvantages of the various different approaches to the preparation of phage mixtures are considered, together with the specifi c conditions that are required for the safe application of phage therapy in general hospitals and the possibilities for the development of personalized phage therapy.

关键词： pseudomonas aeruginosa bacteriophages phage therapy pseudolysogeny phage-bacteria interactions phage-phage interactions

Toyota Motor Corporation： Organizational Culture

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Journal of Philosophy Study 2016年第7期6卷 442-454页

作者： sergey Sosnovskikh University of Greenwich

This paper investigates the organizational culture of one of the largest auto manufacturers in the world Toyota Motor Corporation using various corporate culture and management models. The investigation was conducted in 2009 using qualitative analysis with the help of various secondary sources. The study reveals that the company＇s management style can be characterized as the Family type that implies collectivistic society with male domination, strict rules and laws at work, and long-term orientation. It is also based on several essential principles, such as continuous improvement and learning, respect for people, mutual trust, and teamwork. Two core elements of the Toyota＇s success are technological innovations and qualified human resources.

关键词： Toyota Motor Corporation organizational culture management model Japanese culture Hofstede kaizen

Stabilization of Hyperbolic Chaos by the Pyragas Method

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Journal of Mathematics and System Science 2014年第12期4卷 755-762页

作者： sergey Belyakin Arsen Dzanoev sergey Kuznetsov Physics Faculty Moscow State University Moscow 119992 Russia

For a long time it was a common opinion that hyperbolic attractors are artificial mathematical constructions. However, in the recent papers there were proposed physically realizable systems that possess, in their phase space, the set with features that are very similar to hyperbolic type of attractors. As is known, invariant sets are called hyperbolic attractors of the dynamical system if they are closed, topologically transitive subsets, and every their trajectory possesses uniform hyperbolicity. Very familiar types of the hyperbolic attractors are Smale-Williams＇ solenoid and Plykin＇s attractor. Further, it is well known that chaotic systems are very sensitive to the external perturbations. This property is used for controlling nonlinear systems and chaos suppression. Thus, an important question arises： Is it possible to suppress chaos in systems with hyperbolic attractors because these attractors are structurally stable subsets？ In the present contribution we study the possibility of stabilization of chaotic oscillations in systems with the Smale-Williams hyperbolic attractors by means of the Pyragas method with a delay. It is shown that by means of external perturbation the dynamical system could be controllable： the hyperbolic attractor degenerates into a periodic one.

关键词： Dynamical system hyperbolic attractors Pyragas method

IVlelatonin ameliorates the adverse effects of leptin on sperm

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Asian Journal of Andrology 2017年第6期19卷 647-654页

作者： Fayez A Almabhouh Khairul Osman Siti Fatimah Ibrahim sergey Gupalo Justin Gnanou Effendi Ibrahim Harbindar Jeet Singh Faculty of Medicine Universiti Teknologi MARA Sg Buloh Campus 47000 Sg Buloh Selangor Malaysia Faculty of Allied Health Sciences Universiti Kebangsaan Malaysia Jalan Raja Muda Kuala Lumpur Malaysia Faculty of Medicine and Defence Health National Defence University of Malaysia Kem Sungai Besi 57000 Selangor Malaysia IMMB Faculty of Medicine Universiti Teknologi MARA Sg Buloh Campus 47000 Sg Buloh Selangor Malaysia PPerForM Universiti Teknologi MARA Sg Buloh Campus Selangor Malaysia.

This study examined the effects of melatonin on leptin-induced changes in sperm parameters in adult rats. Five groups of Sprague-Dawley rats were treated with either leptin or leptin and melatonin or melatonin for 6 weeks. Leptin was given daily via the intraperitoneal route （60 μg kg-1 body weight） and melatonin was given in drinking water （10 mg kg-1 or 20 mg kg-1 body weight per day）. Upon completion, sperm count, sperm morphology, 8-hydroxy-2-deoxyguanosine, Comet assay, TUNEL assay, gene expression profiles of antioxidant enzymes, respiratory chain reaction enzymes, DNA damage, and apoptosis genes were estimated. Data were analyzed using ANOVA. Sperm count was significantly lower whereas the fraction of sperm with abnormal morphology, the level of 8-hydroxy-2-deoxyguanosine, and sperm DNA fragmentation were significantly higher in rats treated with leptin only. Micmarray analysis revealed significant upregulation of apoptosis-inducing factor, histone acetyl transferase, respiratory chain reaction enzyme, cell necrosis and DNA repair genes, and downregulation of antioxidant enzyme genes in leptin-treated rats. Real-time polymerase chain reaction showed significant decreases in glutathione peroxidase 1 expression with increases in the expression of apoptosis-inducing factor and histone acetyl transferase in leptin-treated rats. There was no change in the gene expression of caspase-3 （CASP-3）. In conclusion, the adverse effects of leptin on sperm can be prevented by concurrent melatonin administration.

关键词： 8-hydroxy-2-deoxyguanosine DNA fragmentation leptin melatonin sperm

Modern Ab-Initio Calculations on Modified Tomas-Fermi-Dirac Theory

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Open Journal of Modelling and Simulation 2015年第3期3卷 96-103页

作者： sergey Seriy Lenina 23-25 Komsomolsk-on-Amur City Russia

Thomas-Fermi theory is an approximate method, which is widely used to describe the properties of matter at various hierarchical levels (atomic nucleus, atom, molecule, solid, etc.). Special development is achieved using Thomas-Fermi theory to the theory of extreme states of matter appearing under high pressures, high temperatures or strong external fields. Relevant sections of physics and related sciences (astrophysics, quantum chemistry, a number of applied sciences) determine the scope of Thomas-Fermi theory. Popularity Thomas-Fermi theory is related to its relative simplicity, clarity and versatility. The latter means that the result of the calculation by Thomas-Fermi theory applies immediately to all chemical elements: the transition from element to element is as simple scale transformation. These features make it to be a highly convenient tool for qualitative and, in many cases, and quantitative analysis.

关键词： Quantum Mechanics Ab-Initio Calculations Thomas-Fermi Theory Material Science

Modern Ab-initio Calculations Based on Tomas-Fermi-Dirac Theory with Quantum, Correlation and Multi-shells Corrections

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Journal of Chemistry and Chemical Engineering 2014年第7期8卷 744-750页

作者： sergey Seriy Institute of Dynamic Systems Komsomolsk-on-Amur 681013 Russia

Thomas-Fermi theory is an approximate method, which is widely used to describe the properties of matter at various hierarchical levels （atomic nucleus, atom, molecule, solid, etc.）. Special development is achieved using Thomas-Fermi theory to the theory of extreme states of matter appearing under high pressures, high temperatures or strong external fields. Relevant sections of physics and related sciences （astrophysics, quantum chemistry, a number of applied sciences） determine the scope of Thomas-Fermi theory. Popularity Thomas-Fermi theory is related to its relative simplicity, clarity and versatility. The latter means that result of the calculation by Thomas-Fermi theory applies immediately to all chemical elements： the transition from element to element is as simple scale transformation. These features make it highly convenient tool for qualitative and, in many cases, quantitative analysis.

关键词： Quantum mechanics ab-initio calculations Thomas-Fermi theory material science.

High voltage electrical treatments can eco-efficiently promote the production of high added value peptides during chymotryptic hydrolysis of β-lactoglobulin

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Food Bioscience 2022年第3期47卷 197-210页

作者： Rock-Seth Agoua Laurent Bazinet Jacinthe Thibodeau Eugène Vorobiev Nabil Grimi sergey Mikhaylin Institute of Nutrition and Functional Foods (INAF) Dairy Research Center (STELA)Food Science DepartmentUniversité LavalQuébecQCCanada Laboratory of Food Sustainability (EcoFoodLab) Food Science DepartmentUniversité LavalQuébecQCCanada Laboratoire de Transformation Alimentaire et Procédés Électro-Membranaires (LTAPEM) Food Science DepartmentUniversité LavalQuébecQCCanada University of Technology of Compiègne Laboratory of Agro-industrial technologiesCompiègneFrance

Chymotryptic hydrolysis of β-lactoglobulin (β-lg) leads to the release of a wide range of biofunctional ***,the proteolysis of native β-lg is limited due to its compact globular structure,thus ending with low yields of *** our previous study showed that eco-efficient High Voltage Electric Treatments (HVET),namely Pulsed Electric Fields (PEF) and Electric Arc (ARC),of β-lg substantially improved its enzymatic hydrolysis,no information regarding the nature of released peptides is available up to ***,the time-dependent release of peptides and the dynamics of this release were discussed in the current *** analysis of the final hydrolysates showed that chymotrypsinolysis of HVET samples released 19% more peptides with higher concentration than the native and preheated ***,1-min HVET were found to be more efficient than 10-min ones as they led to the release of bioactive peptides (even without chymotrypsin) with higher eco-efficiency scores.

关键词： β-lactoglobulin Peptides High-voltage electrical treatments Eco-efficiency Chymotrypsin Hydrolysis.

The Problem of AIDS May Have Already Solved

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World Journal of AIDS 2014年第4期4卷 396-401页

作者： sergey Makarov Independent Researcher Riga Latvia

This article describes an alternative approach to the problem of AIDS. The author proposes a new theory. In this theory, HIV is not a “classic virus”, but a parasitic program that does not have a material carrier.

关键词： AIDS HIV Immune Deficiency Parasitic Program Lymphocytes Hyperthermia