BACKGROUND Human immunodeficiency virus(HIV)is a major public health concern,particularly in Africa where HIV rates remain *** women are at an increased risk of acquiring HIV,which has a significant impact on both mat...
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BACKGROUND Human immunodeficiency virus(HIV)is a major public health concern,particularly in Africa where HIV rates remain *** women are at an increased risk of acquiring HIV,which has a significant impact on both maternal and child *** To review summarizes HIV seroprevalence among pregnant women in *** also identifies regional and clinical characteristics that contribute to study-specific estimates *** The study included pregnant women from any African country or region,irrespective of their symptoms,and any study design conducted in any *** electronic literature searches,articles published until February 2023 were *** quality of the included studies was *** DerSimonian and Laird random-effects model was applied to determine HIV pooled seroprevalence among pregnant women in *** and sensitivity analyses were conducted to identify potential sources of *** was assessed with Cochran's Q test and I2 statistics,and publication bias was assessed with Egger's *** A total of 248 studies conducted between 1984 and 2020 were included in the quantitative synthesis(meta-analysis).Out of the total studies,146(58.9%)had a low risk of bias and 102(41.1%)had a moderate risk of *** HIV-positive pregnant women died in the included *** overall HIV seroprevalence in pregnant women was estimated to be 9.3%[95%confidence interval(CI):8.3-10.3].The subgroup analysis showed statistically significant heterogeneity across subgroups(P<0.001),with the highest seroprevalence observed in Southern Africa(29.4%,95%CI:26.5-32.4)and the lowest seroprevalence observed in Northern Africa(0.7%,95%CI:0.3-1.3).CONCLUSION The review found that HIV seroprevalence among pregnant women in African countries remains significant,particularly in Southern African *** review can inform the development of targeted public health interventions to address high HIV seroprevalence
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