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Checkpoint Management with Double Modular Redundancy Based on the Probability of Task Completion

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Journal of Computer Science & Technology 2012年第2期27卷 273-280页

作者： seong Woo Kwak Kwan-Ho You Jung-min Yang Department of Electronic Engineering Keimyung University School of Information & Communication Engineering Sungkyunkwan University Department of Electrical Engineering Catholic University of Daegu

This paper proposes a checkpoint rollback strategy for real-time systems with double modular *** built-in fault-detection and spare processors,our scheme is able to recover from both transient and permanent *** comparisons are conducted at each ***,the states stored in two consecutive checkpoints of one processor are compared for checking integrity of the *** states of two processors are also compared for detecting faults and the system rolls back to the previous checkpoint whenever required by logic of the proposed scheme.A Markov model is induced by the fault recovery scheme and analyzed to provide the probability of task completion within its *** optimal number of checkpoints is selected so as to maximize the probability of task completion.

关键词： checkpoint scheme double modular redundancy (DMR) real-time task fault tolerance Markov model

Cavernous mesenteric lymphangiomatosis mimicking metastasis in a patient with rectal cancer:A case report

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World Journal of Gastroenterology 2009年第31期15卷 3947-3949页

作者： seong Su hwang Hyun Joo Choi Soo Youn Park Department of Radiology St.Vincent's HospitalCollege of MedicineThe Catholic University of Korea Department of Pathology St.Vincent's HospitalCollege of MedicineThe Catholic University of Korea

Lymphangioma usually occurs in children and usually involves the skin. Mesenteric lymphangioma is extremely rare in adults. Typically, lymphangioma appears on computed tomography (CT) as a lower attenuation of a cystic mass, however, some cases appear to be a solid mass. We describe the CT and 18F-FDG positron emission tomography/CT appearance in a case of jejunal and mesenteric cavernous lymphangi-omatosis mimicking metastasis in an adult patient with rectal cancer.

关键词：淋巴管瘤肠系膜直肠癌海绵状病例报告模仿计算机断层扫描患者

Upconverting nanoparticle-containing erythrocyte-sized hemoglobin microgels that generate heat,oxygen and reactive oxygen species for suppressing hypoxic tumors

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Bioactive Materials 2023年第4期22卷 112-126页

作者： Hanju Kim Johyun Yoon hwang Kyung Kim Woo Tak Lee Nguyen Thi Nguyen Xuan Thien Le Eun-Hee Lee Eun seong Lee Kyung Taek Oh Han-Gon Choi Yu Seok Youn School of Pharmacy Sungkyunkwan University2066 Seobu-roJangan-guSuwonGyeonggi-do16419Republic of Korea College of Pharmacy Korea University2511 Sejong-roSejong30019Republic of Korea Department of Biotechnology and Department of Biomedical-Chemical Engineering the Catholic University of Korea43 Jibong-roBucheon-siGyeonggi-do14662Republic of Korea College of Pharmacy Chung-Ang University84 Heukseok-roDongjak-guSeoul06974Republic of Korea College of Pharmacy Hanyang University55Hanyangdaehak-roSangnok-guAnsan15588Republic of Korea

Inspired by erythrocytes that contain oxygen-carrying hemoglobin(Hb)and that exhibit photo-driven activity,we introduce homogenous-sized erythrocyte-like Hb microgel(μGel)systems(5-6μm)that can(i)emit heat,(ii)supply oxygen,and(iii)generate reactive oxygen species(ROS;1O2)in response to near-infrared(NIR)laser *** μGels consist of Hb,bovine serum albumin(BSA),chlorin e6(Ce6)and erbium@lutetium upconverting nanoparticles(UCNPs;~35 nm)that effectively convert 808 nm NIR light to 660 nm visible *** Hb μGels are capable of releasing oxygen to help generate sufficient reactive oxygen species(^(1)O_(2))from UCNPs/Ce6 under severely hypoxic condition upon NIR stimulation for efficient photodynamic ***,the Hb μGels emit heat and increase surface temperature due to NIR light absorption by heme(iron protoporphyrin IX)and display photothermal *** changing the Hb/UCNP/Ce6 ratio and controlling the amount of NIR laser irradiation,it is possible to formulate bespoke Hb μGels with either photothermal or photodynamic activity or both in the context of combined therapeutic *** Hb μGels effectively suppress highly hypoxic 4T1 cell spheroid growth and xenograft mice tumors in vivo.

关键词： Hemoglobin microgel Upconversion Photothermal therapy Photodynamic therapy Hypoxic tumors Oxygen-generation

Clinical features of HBs Ag seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study

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World Journal of Gastroenterology 2016年第44期22卷 9836-9843页

作者： Young min Park seong Gyu Lee Hepatology Center Department of Internal Medicine and Biomedical Research Center Bundang Jesaeng General Hospital epartment of Laboratory Medicine Bundang Jesaeng General Hospital

AIM To investigate the characteristic features of hepatitis B surface antigen(HBs Ag) seroclearance among Korean hepatitis B virus(HBV) *** Carriers with HBs Ag seroclearance were selected by analyzing longitudinal data collected from 2003 to 2015. The period of time from enrollment to the negative conversion of HBs Ag(HBs Ag-NC) was compared by stratifying various factors, including age, sex, hepatitis B e antigen(HBe Ag), HBV DNA, sequential changes in the signal-to-cutoff ratio of HBs Ag(HBs Ag-SCR), as measured by qualitative HBs Ag assay, and chronic liver disease on ultrasonography(US-CLD). Quantification of HBV DNA and HBs Ag(HBs Ag-QNT) in the serum was performed by commercial *** Among the 1919 carriers, 90(4.7%) exhibited HBs AgNC at 6.2 ± 3.6 years after registration, with no differences observed among the different age groups. Among these carriers, the percentages of those with asymptomatic liver cirrhosis(LC) and hepatocellular carcinoma(HCC) at registration were 31% and 7.8%, respectively. The frequency of HBs Ag-NC significantly differed according to the HBV DNA titer and US-CLD. HBe Ag influenced HBs Ag-NC in the 40-50 and 50-60 year age groups. HBs Ag-SCR < 1000 was correlated with an HBs Ag-QNT < 200 IU/m L. A gradual decrease in the HBs Ag-SCR to < 1000 predicted HBs Ag-NC. Six patients developed HCC after registration, including two before and four after HBs Ag-NC. The rate at which the patients developed new HCC after HBs Ag seroclearance was 4.8%. LC with excessive drinking and vertical infection were found to be risk factors for HCC in the HBs Ag-NC *** HCC surveillance should be continued after HBs Ag seroclearance. An HBs Ag-SCR < 1000 and its decrease in sequential testing are worth noting as predictive markers of HBs Ag loss.

关键词： Hepatocellular carcinoma Hepatitis B virus Hepatitis B Surface antigen HBs Ag Seroconversion Hepatitis B e antigen HBe Ag Liver cirrhosis

Determination of the mechanism of photoinduced toxicity of selected metal oxide nanoparticles(ZnO,CuO,Co_3O_4 and TiO_2)to *** bacteria

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Journal of Environmental Sciences 2013年第5期25卷 882-888页

作者： Thabitha P.Dasari Kavitha Pathakoti Huey-min hwang Environmental Science Ph.D.Program Jackson State UniversityJacksonMS 39217USA Department of Biology Jackson State UniversityJacksonMS 39217USA

Cytotoxicity of selected metal oxide nanoparticles（MNPs）（ZnO,CuO,Co 3 O 4 and TiO 2）was investigated in Escherichia coli both under light and dark *** experiments were conducted with spread plate counting and the LC 50 values were *** determined the mechanism of toxicity via measurements of oxidative stress,reduced glutathione,lipid peroxidation,and metal *** overall ranking of the LC 50 values was in the order of ZnO 〈 CuO 〈 Co 3 O 4 〈 TiO 2 under dark condition and ZnO 〈 CuO 〈 TiO 2 〈 Co 3 O 4 under light *** MNPs were the most toxic among the tested *** results indicate depletion of reduced glutathione level and elevation of malondialdehyde level correlated with the increase in oxidative *** metal ions were found to have partial effect on the toxicity of MNPs to *** summary,the dynamic interactions of multiple mechanisms lead to the toxicity of the tested MNPs to ***.

关键词： metal oxide nanoparticles reactive oxygen species median lethal concentration reduced glutathione lipid peroxidation

The Southern Annular Mode(SAM) in PMIP2 Simulations of the Last Glacial Maximum

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Advances in Atmospheric Sciences 2014年第4期31卷 863-878页

作者： seong-Joong KIM L Junmei Baek-min KIM Korea Polar Research Institute KORDI Chinese Academy of Meteorological Sciences

The increasing trend of the Southern Annular Mode （SAM） in recent decades has influenced climate change in the Southem Hemisphere （SH）.How the SAM will respond increased greenhouse gas concentrations in the future remains *** the variability of the SAM in the past under a colder climate such as during the Last Glacial Maximum （LGM） might provide some understanding of the response of the SAM under a future warmer *** analyzed the changes in the SAM during the LGM in comparison to pre-industrial （PI） simulations using five coupled ocean-atmosphere models （CCSM,FGOALS,IPSL,MIROC,HadCM） from the second phase of the Paleoclimate Modelling Intercomparison Project （PMIP2）.In CCSM,MIROC,IPSL,and FGOALS,the variability of the simulated SAM appears to be reduced in the LGM compared to the PI simulations,with a decrease in the standard deviation of the SAM ***,four out of the five models suggest a weaker SAM amplitude in the LGM consistent with a weaker SH polar vortex and westerly winds found in some proxy records and model *** weakening of the SAM in the LGM was associated with an increase in the vertical propagation of Rossby waves in southern high latitudes.

关键词： Southern Annular Mode Last Glacial Maximum PMIP2 Southern Hemisphere westerly winds

Electrochemical characteristics of stainless steel using impressed current cathodic protection in seawater

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中国有色金属学会会刊：英文版 2009年第4期19卷 930-934页

作者： Seok-Ki JANG min-Su HAN seong-Jong KIM Division of Marine Engineering Mokpo Maritime University

Stainless steels such as STS 304,316 and 630 are frequently used as shaft materials in small fiber reinforced polymer(FRP) fishing *** the shaft material is exposed to a severely corrosive environment such as seawater,it should be protected using appropriate *** impressed current cathodic protection was used to inhibit corrosion in shaft *** anodic polarization,passivity was remarkably more evident in STS 316 stainless steel than in STS 304 and STS *** pitting potentials of STS 304,316,and 630 stainless steels were 0.30,0.323,and 0.260 V,*** concentration polarization due to oxygen reduction and activation polarization due to hydrogen generation were evident in the cathodic polarization trends of all three stainless *** 316 had the lowest current densities in all potential ranges,and STS 630 had the *** analysis showed that STS 316 was the most noble in the *** addition,the corrosion current density was the lowest for STS 316.

关键词：外加电流阴极保护 316不锈钢电化学特性海水腐蚀电流密度材料腐蚀阳极极化 STS

Multiplexed DNA-functionalized graphene sensor with artificial intelligence-based discrimination performance for analyzing chemical vapor compositions

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Microsystems & Nanoengineering 2023年第2期9卷 113-125页

作者： Yun Ji hwang Heejin Yu Gilho Lee Iman Shackery Jin seong Youngmo Jung Seung-Hyun Sung Jongeun Choi seong Chan Jun School of Mechanical Engineering Yonsei University500Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

This study presents a new technology that can detect and discriminate individual chemical vapors to determine the chemical vapor composition of mixed chemical composition in situ based on a multiplexed DNA-functionalized graphene(MDFG)nanoelectrode without the need to condense the original vapor or target *** the best of our knowledge,our artificial intelligence(Al)-operated arrayed electrodes were capable of identifying the compositions of mixed chemical gases with a mixed ratio in the early *** innovative technology comprised an optimized combination of nanodeposited arrayed electrodes and artificial intelligence techniques with advanced sensing capabilities that could operate within biological limits,resulting in the verification of mixed vapor chemical *** selective sensors that are tolerant to high humidity levels provide a target for"breath chemovapor fingerprinting"for the early diagnosis of *** feature selection analysis achieved recognition rates of 99%and above under low-humidity conditions and 98%and above under humid conditions for mixed chemical *** 1D convolutional neural network analysis performed better,discriminating the compositional state of chemical vapor under low-and high-humidity conditions almost *** study provides a basis for the use of a multiplexed DNA-functionalized graphene gas sensor array and artificial intelligence-based discrimination of chemical vapor compositions in breath analysis applications.

关键词： humidity functional intelligence

Hypothyroidism affects astrocyte and microglial morphology in type 2 diabetes

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Neural Regeneration Research 2013年第26期8卷 2458-2467页

作者： Sung min Nam Yo Na Kim Dae Young Yoo Sun Shin Yi Jung Hoon Choi In Koo hwang Je Kyung seong Yeo Sung Yoon Department of Anatomy and Cell Biology College of Veterinary Medicine Research Institute for Veterinary Science Seoul National University Department of Biomedical Laboratory Science College of Biomedical Sciences Soonchunhyang University Department of Anatomy College of Veterinary Medicine Kangwon National University

In the present study, we investigated the effects of hypothyroidism on the morphology of astrocytes and microglia in the hippocampus of Zucker diabetic fatty rats and Zucker lean control rats. To induce hypothyroidism, Zucker lean control and Zucker diabetic fatty rats at 7 weeks of age orally received the vehicle or methimazole, an anti-thyroid drug, treatment for 5 weeks and were sacrificed at 12 weeks of age in all groups for blood chemistry and immunohistochemical staining. In the me- thimazole-treated Zucker lean control and Zucker diabetic fatty rats, the serum circulating triiodo- thyronine （T3） and thyroxine （＇I＂4） levels were significantly decreased compared to levels observed in the vehicle-treated Zucker lean control or Zucker diabetic fatty rats. This reduction was more prominent in the methimazole-treated Zucker diabetic fatty group. Glial fibrillary acidic protein im- munoreactive astrocytes and ionized calcium-binding adapter molecule 1 （Iba-1）-immunoreactive microglia in the Zucker lean control and Zucker diabetic fatty group were diffusely detected in the hippocampal CA1 region and dentate gyrus. There were no significant differences in the glial fibril- lary acidic protein and Iba-1 immunoreactivity in the CA1 region and dentate gyrus between Zucker lean control and Zucker diabetic fatty groups. However, in the methimazole-treated Zucker lean control and Zucker diabetic fatty groups, the processes of glial fibrillary acidic protein immunoreac- tive astrocytes and Iba-1 immunoreactive microglia, were significantly decreased in both the CA1 region and dentate gyrus compared to that in the vehicle-treated Zucker lean control and Zucker diabetic fatty groups. These results suggest that diabetes has no effect on the morphology of as- trocytes and microglia and that hypothyroidism during the onset of diabetes prominently reduces the processes of astrocytes and microglia.

关键词： neural regeneration astrocytes microglia diabetes hypothyroidism complications thyroid hormone obesity methimazole Zucker diabetic fatty rat grants-supported paper neuroregeneration