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Synthesis of Al-doped ZnO Nanorods via Microemulsion Method and Their Application as a CO Gas Sensor

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Journal of Materials Science & Technology 2015年第6期31卷 639-644页

作者： Sang Kyoo Lim seong hui hong Sung-Ho Hwang Won Mi Choi Soonhyun Kim Hyunwoong Park Min Gi Jeong Division of Nano & Bio Technology Daegu Gyeongbuk Institute of Science and Technology(DGIST) School of Energy Engineering Kyungpook National University Department of Advanced Organic Materials Engineering Yeungnam University

Aluminum doped ZnO(AZO) nanorods were synthesized by microemulsion method with different types of *** phase and the morphology of the above nanorods were investigated by scanning electron microscopy(SEM) and X-ray diffraction(XRD).SEM observations showed that the ZnO nanorods had diameters around about 50—200 nm and lengths up to several *** CO gas sensing properties of the AZO nanorods were tested at operating temperatures of 200,300,350 and 400 ℃.It was found that AZO nanorods based sensor exhibited the highest sensitivity to CO at 350℃.

关键词： Zinc oxide Nanorod Microemulsion Aluminum CO and g

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li Wei Zhang Jian Wu hui hong Wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

Iksan526 Rice Callus Extract Induces Dedifferentiation of Rabbit Articular Chondrocytes via ERK1/2 and PI-3K/Akt Pathways

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Rice science 2020年第6期27卷 504-514页

作者： seong-hui EO Song Ja Kim Department of Biological Sciences College of Natural SciencesKongju National UniversityGongju 32588Republic of Korea

The resveratrol-enriched transgenic rice line Iksan526(IS526),first developed by the Rural Development Administration of Korea using genetic engineering techniques,shows beneficial health effects in mitigating metabolic syndrome and ***,the effects of IS526 on the differentiation of chondrocytes and the underlying mechanism have not been investigated in *** this study,the effects and cellular regulatory mechanisms of IS526 on rabbit articular chondrocytes were *** IS526 callus extract treatment,the expression levels of differentiation-related proteins were detected via western blotting,Alcian blue staining and immune-luorescence ***526 decreased the type Ⅱ collagen and proteoglycan levels in dose-and time-dependent *** further analyzed the effects of IS526 on skeleton genesis in zebrafish larvae using Alcian blue staining,which showed a reduction in cartilage formation along with increased production of matrix metalloproteinase(MMP)-***526 also increased the phosphorylation of ERK1/2 and p38 kinase but inhibited the phosphorylation of *** inhibition of MMP-13 blocked the IS526-induced decrease in type Ⅱ collagen *** of p38 kinase or PI-3K/Akt with SB203580 and LY294002 enhanced the suppression of type Ⅱ collagen,but the blockage of ERK-1/2 by PD98059 rescued IS526-induced *** results suggested that IS526 regulates type Ⅱ collagen and MMP-13 expression via the ERK1/2 and PI-3K/Akt pathways in rabbit articular chondrocytes.

关键词： rice chondrocyte typeⅡcollagen matrix metalloproteinase-13 rice callus extract

A reviving templating method for multiple nanostructures

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Science China Materials 2017年第5期60卷 461-462页

作者： hui-hui Li Shu-hong Yu Division of Nanomaterials & Chemistry Hefei National Laboratory for Physical Sciences at the Microscale Department of Chemistry University ofScience and Technology of China Hefei 230026 China

Binary materials,comprised by two dissimilar components in one matrix,already exist in nature from the subatomic to the universal scale with different kinds of forms(e.g.,nuclei and electrons,matter and antimatter)[1]... 详细信息

关键词：英语阅读理解材料科学

粮食气味物质的提取、关键组分判别及其在储藏中的应用研究进展

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食品科学 2025年第1期46卷 266-273页

作者：李慧洪习文王争艳王艳艳河南工业大学粮食和物资储备学院河南郑州450001

粮食气味物质受粮食种类、储藏条件、储藏时间及是否受有害生物污染等多种因素影响,气味物质种类及含量能够及时反映粮食是否变质或受有害生物危害。首先,本文概述目前常用的粮食气味物质的提取和鉴定技术,总结不同状态粮食气味物质组成... 详细信息

粮食气味物质受粮食种类、储藏条件、储藏时间及是否受有害生物污染等多种因素影响,气味物质种类及含量能够及时反映粮食是否变质或受有害生物危害。首先,本文概述目前常用的粮食气味物质的提取和鉴定技术,总结不同状态粮食气味物质组成,发现烷烃类、酸类、醛类和醇类等物质赋予粮食特有的气味,而不同的储藏环境和粮食状态下,其气味物质存在较大差异。其次,探讨粮食中特征气味物质的分析方法,梳理粮食关键气味物质可能的代谢途径,归纳水稻和小麦中特征气味物质,其中稻谷中特征气味物质2-乙酰基-1-吡咯啉的生成机制也已得到初步确认。最后,对气味物质在粮食安全储藏领域的应用进行概述,提出深入分析、挖掘粮食气味物质数据,构建新型预测模型以快速、精准检测粮食品质将成为未来粮食气味物质研究领域的重要方向;同时,部分气味物质也被证实对粮仓中有害生物具有防控作用,将成为未来研发新型绿色储粮药剂的重要来源。

关键词：粮食气味物质判别方法代谢途径安全储藏

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Expression and purification of a functional human hepatitis B virus polymerase

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World Journal of Gastroenterology 2010年第45期16卷 5752-5758页

作者： Dipendra Raj Pandeya seong-Tshool hong Department of Microbiology and Immunology Institute of Medical ScienceChonbuk National University Medical SchoolChonjuChonbuk 561-712South Korea

AIM: To identify a method for efficient large-scale purification of functional hepatitis B virus polymerase (HBV-Pol) without addition of cellular factors. METHODS: Full-length HBV-Pol (843 amino acids) tagged with 5' end Polyhistidine was expressed at a high level in an Escherichia coli (E. coli ) system. Sodium dodecyl sulfate lysis buffer was utilized to dissolve insoluble HBV-Pol, and Ni-NTA resin affinity chromatography was utilized for HBV-Pol purification. Most recombinant HBV-Pol was eluted with 100 mmol/L imidazole in the presence of NP-40, a weak detergent that keeps HBV-Pol in solution. A reducing agent was utilized throughout the purification steps to keep soluble HBV-Pol from redundant disulfide bond formation. RESULTS: The large-scale production of functional intact human HBV-Pol was achieved in an E. coli expression system. Purified HBV-Pol showed stable reverse transcriptase activity and DNA polymerase activity. The purified protein was of high purity and had stable reverse transcriptase ***: Large-scale production of HBV-Pol in pure form should facilitate crystallization and detailed analysis of the structure and mechanism of HBV-Pol. Ability of this purification approach to obtain human HBV-Pol in an enzymatically active form should be helpful for development of drugs for treatment of chronic hepatitis B.

关键词： Hepatitis B Virus Virus polymerase Reverse transcriptase Detergent

Entry,egress and vertical transmission of SARS-CoV-2

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Journal of Molecular Cell Biology 2021年第3期13卷 168-174页

作者： hui Zhang hong Zhang National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBeijing 100049China

The high infectivity and pathogenicity of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have caused the COVID-19 outbreak,one of the most devastating pandemics in more than a *** pandemic has already left a trail of destruction,including enormous loss of life,a global economic slump,and widespread psychological *** assiduous world-wide endeavors,an effective cure for COVID-19 is still ***,infected neonates and children have relatively mild clinical manifestations and a much lower fatality rate than elderly *** studies have unambiguously demonstrated the vertical transmission of SARS-CoV-2 from infected pregnant women to fetuses,which creates yet another challenge for disease *** this review,we will summarize the molecular mechanism for entry of SARS-CoV-2 into host cells,the basis for the failure of the lungs and other organs in severe acute cases,and the evidence for congenital transmission.

关键词： SARS-CoV-2 COVID-19 ACE2 TMPRSS2 placental transmission

Meso-porous silicon-coated carbon nanotube as an anode for lithium-ion battery

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Nano Research 2016年第7期9卷 2174-2181页

作者： Won-Sik Kim Jonghyun Choi seong-Hyeon hong Department of Materials Science and Engineering and Research Institute of Advanced Materials Seoul National University Seoul 151-744 Republic of Korea

Meso-porous Si-coated carbon nanotube （CNT） composite powders were prepared by combining a sol-gel method and the magnesiothermic reduction process. Meso-porous Si-coated CNT electrodes exhibit excellent cycle and rate performances as anodes in Li-ion batteries （LIBs）, which can be attributed to the efficient accommodation of volume change from meso-porous Si structure and the enhanced electrical conductivity from CNT core. This simple synthesis and subsequent reduction process provide a scalable route for the large-scale production of Si-C composite nanostructures, which can be utilized in a variety of applications, such as in photocatalysis, photoelectrochemical cells （PECs）, and LIBs.

关键词： meso-porous carbon nanotube (CNT) magnesiothermic reduction battery

Recent advances in new-type molecular switches

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Science China Chemistry 2015年第6期58卷 916-921页

作者： hong Li Da-hui Qu Key Laboratory for Advanced Materials and Institute of Fine Chemicals East China University of Science & Technology

Molecular switches that can undergo reversible switching between two or more different states in response to external stimuli have been used in the fabrication of various optoelectronic devices and smart materials for many decades, and also found many applications in sensing, molecular self-assembly and photo-controlled biological systems. Recently, mechanically interlocked molecules, such as rotaxanes and catenanes, and molecular rotary motors based on overcrowded alkenes have emerged as two new kinds of molecular switches. Some novel applications of above-mentioned molecular switches have been discovered. In this mini review, we mainly highlight noticeable achievements over the past decade in this field, and summarize the applications of new types of molecular switches, for instance, controlling the chiral space to regulate catalytic reaction as organocatalysts, controlling molecular motions, synthesizing a peptide in a sequence-specific manner and modulating the wettability of the self-assembled monolayers.

关键词： molecular switches rotaxane molecular motor stimuli-responsive function