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Advances in Microbiology 2019年第9期9卷 824-841页

作者： Sushanta Ghosh Surajit De Mandal Nandita Nath David L. Kaipeng Lovely Rahaman senthil kumar nachimuthu Bipin kumar Sharma Department of Microbiology Tripura University Suryamaninagar India Department of Biotechnology Mizoram University Aizawl India

As per tradition from hundreds of years the Koloi tribes of Tripura are preparing “Gora”-therice based fermented beer which is very good in taste and aroma applying their traditional indigenous brewing techniques. In this study, an attempt has been made to identify the indigenous yeast which is the main causative agent for fermentation and to investigate its fermentation ability with an industrial Saccharomyces cerevisiaes train. After investigation based on culture dependent phenotypic characteristics like-staining and biochemical characterization, primarily the responsible yeast species was determined as Pichia kudriavzevii and further confirmed followed by 18S rRNA ribotyping and the sequences was deposited at Gene bank and NCBI bearing specific accession number. In the comparative analysis, it has been found a significant similarities in all aspects of nutritional and alcohol percentages with the industrial strain in laboratory condition. The alcohol percentage in the rice beer “Gora” measured 6.40 ± 0.008% v/v. The study may be the first scientific investigation of its kind about this indigenous yeast strain isolated from “Gora” of this Indo-Burma biodiversity region and may provide sufficient background and potentiality for promoting these kinds of indigenous alcoholic beverages for small scale commercialization to strengthen the rural livelihood as well as to maintain immaterial cultural heritage.

关键词： Beer Yeast Fermentation 18S rRNA

The synergistic interplay of artificial intelligence and digital twin in environmentally planning sustainable smart cities:A comprehensive systematic review

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Environmental Science and Ecotechnology 2024年第4期20卷 79-104页

作者： Simon Elias Bibri Jeffrey Huang senthil kumar Jagatheesaperumal John Krogstie Swiss Federal Institute of Technology Lausanne(EPFL) Institute of Computer and Communication Sciences(IINFCOM)School of ArchitectureCivil and Environmental Engineering(ENAC)Media and Design Laboratory(LDM)1015LausanneSwitzerland Department of Electronics&Communication Engineering Mepco Schlenk Engineering CollegeSivakasi626005TamilnaduIndia Department of Computer Science Norwegian University of Science and Technology(NTNU)TrondheimNorway

The dynamic landscape of sustainable smart cities is witnessing a significant transformation due to the integration of emerging computational technologies and innovative *** advancements are reshaping data-driven planning strategies,practices,and approaches,thereby facilitating the achievement of environmental sustainability *** transformative wave signals a fundamental shift d marked by the synergistic operation of artificial intelligence(AI),artificial intelligence of things(AIoT),and urban digital twin(UDT)*** previous research has largely explored urban AI,urban AIoT,and UDT in isolation,a significant knowledge gap exists regarding their synergistic interplay,collaborative integration,and collective impact on data-driven environmental planning in the dynamic context of sustainable smart *** address this gap,this study conducts a comprehensive systematic review to uncover the intricate interactions among these interconnected technologies,models,and domains while elucidating the nuanced dynamics and untapped synergies in the complex ecosystem of sustainable smart *** to this study are four guiding research questions:*** theoretical and practical foundations underpin the convergence of AI,AIoT,UDT,data-driven planning,and environmental sustainability in sustainable smart cities,and how can these components be synthesized into a novel comprehensive framework?*** does integrating AI and AIoT reshape the landscape of datadriven planning to improve the environmental performance of sustainable smart cities?*** can AI and AIoT augment the capabilities of UDT to enhance data-driven environmental planning processes in sustainable smart cities?*** challenges and barriers arise in integrating and implementing AI,AIoT,and UDT in data-driven environmental urban planning,and what strategies can be devised to surmount or mitigate them?Methodologically,this study involves a rigorous analysis and synthesis of studies publis

关键词： Sustainable smart cities Artificial intelligence Artificial intelligence of things Urban digital twin Data-driven urban planning Environmental planning Environmental sustainability

Reliable Data Collection Model and Transmission Framework in Large-Scale Wireless Medical Sensor Networks

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 1077-1102页

作者： Haosong Gou Gaoyi Zhang RenêRipardo Calixto senthil kumar Jagatheesaperumal Victor Hugo C.de Albuquerque China Mobile Group Sichuan Co. Ltd.Chengdu640041China Department of Teleinformatics Engineering Federal University of CearáFortaleza60455-970Brazil Department of Electronics&Communication Engineering Mepco Schlenk Engineering CollegeSivakasi626005India

Large-scale wireless sensor networks(WSNs)play a critical role in monitoring dangerous scenarios and responding to medical ***,the inherent instability and error-prone nature of wireless links present significant challenges,necessitating efficient data collection and reliable transmission *** paper addresses the limitations of existing data transmission and recovery protocols by proposing a systematic end-to-end design tailored for medical event-driven cluster-based large-scale *** primary goal is to enhance the reliability of data collection and transmission services,ensuring a comprehensive and practical *** approach focuses on refining the hop-count-based routing scheme to achieve fairness in forwarding ***,it emphasizes reliable data collection within clusters and establishes robust data transmission over multiple *** systematic improvements are designed to optimize the overall performance of the WSN in real-world *** results of the proposed protocol validate its exceptional performance compared to other prominent data transmission *** evaluation spans varying sensor densities,wireless channel conditions,and packet transmission rates,showcasing the protocol’s superiority in ensuring reliable and efficient data *** systematic end-to-end design successfully addresses the challenges posed by the instability of wireless links in *** prioritizing fairness,reliability,and efficiency,the proposed protocol demonstrates its efficacy in enhancing data collection and transmission services,thereby offering a valuable contribution to the field of medical event-drivenWSNs.

关键词： Wireless sensor networks reliable data transmission medical emergencies cluster data collection routing scheme

Structural,morphological,optical and antibacterial performances of rare earth(Sm)-doped ZnO nanorods

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Journal of Rare Earths 2024年第11期42卷 2119-2127页

作者： A.Ravi J.Samuel S.Sahaya Jude Dhas S.Usharani Turibius Simon D.senthil kumar S.K.Jasmin Vijitha A.Sivakumar Raju Suresh kumar C.S.Biju Department of Physics University College of Engineering Department of Physics and Research Centre Malankara Catholic College Manonmaniam Sundaranar University Saveetha School of Engineering Saveetha Institute of Medical and Technical SciencesSaveetha University Department of Chemistry S.I.V.E.T College Department of Biotechnology Vivekanandha College of Arts and Science for Woman (Autonomous) Department of Physics Vel Tech Rangarajan Dr.Sagunthala R & D Institute of Science and Technology Department of Physics & Research Centre Muslim Arts College Key Laboratory of High-temperature and High-pressure Study of the Earth's Interior Institute of GeochemistryChinese Academy of Sciences Department of Chemistry College of ScienceKing Saud University Department of Physics St. Alphonsa College of Arts and Science

The significant rise of ultra-violet（UV） radiation and pathogenic infectious bacteria poses a serious threat to global *** researchers' interests are attracted by novel materials with strong UVblocking ability,antibacterial activity and low toxicity to other *** this case,a simple wet chemical method with different annealing temperatures（400,500,and 600℃） was employed to create highly effective rare earth（Sm）-doped ZnO ***（101） plane of wurtzite ZnO shifts towards a lower angle with increasing annealing temperature,according to the X-ray diffraction（XRD） study findings,which additionally establishes the consequence of lattice *** of doublet peaks of Sm 3d(Sm 3d5/2and Sm 3d3/2) in the X-ray photoelectron spectroscopy（XPS） spectrum clearly validates the substitution of Sm3+ions in the 500℃-annealed *** 500℃-annealed nanorods exhibit combined performances of the wide band gap,improved UV absorbance,and vivid green luminescent emission（563 nm）.Additio nally,the nanorods have favorable UV-blocking execution of 96% for UVA at 360 nm,92% for UVB at 320 nm,and 57% for UVC at 225 nm,which is greater than the majority of ZnO-related materials that have been reported up to this *** doping is also appropriate for improving bacterial inhibition against the two studied strains（Escherichia coli and Staphylococcus aureus）,in addition to the intriguing features discussed ***,with maximum inhibition zone diameters of 20±0.72 and 18±0.57 mm,respectively,these nanorods exhibit high inhibitory action against *** and *** bacterial *** rare earth-doped material developed during the current experiment,which was annealed at 500℃,could potentially serve as an effective replacement for UV-blocking and antibacterial material,especially for biomedical applications.

关键词： Bacterial inhibition Metal oxide Rare earth doping UV-Shielding Wet chemical method

Deep Transfer Learning Techniques in Intrusion Detection System-Internet of Vehicles: A State-of-the-Art Review

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Computers, Materials & Continua 2024年第8期80卷 2785-2813页

作者： Wufei Wu Javad Hassannataj Joloudari senthil kumar Jagatheesaperumal Kandala N.V.P.SRajesh Silvia Gaftandzhieva Sadiq Hussain Rahimullah Rabih Najibullah Haqjoo Mobeen Nazar Hamed Vahdat-Nejad Rositsa Doneva School of Information Engineering Nanchang UniversityNanchang330031China Department of Computer Engineering Technical and Vocational University(TVU)Tehran***Iran Department of Computer Engineering University of BirjandBirjand***Iran Department of Computer Engineering Babol BranchIslamic Azad UniversityBabol***Iran Department of Electronics&Communication Engineering Mepco Schlenk Engineering CollegeSivakasi626005India School of Electronics Engineering VIT-AP UniversityNear Vijayawada522237India Faculty of Mathematics and Informatics University of Plovdiv Paisii HilendarskiPlovdiv4000Bulgaria Examination Branch Dibrugarh UniversityDibrugarh786004India Department of Computer Engineering Faculty of EngineeringUniversity of BirjandBirjand***Iran Faculty of Electrical and Computer Engineering University of BirjandBirjand***Iran Malaysian Institute of Information Technology Universiti Kuala LumpurKuala Lumpur50250Malaysia Faculty of Physics and Technology University of Plovdiv Paisii HilendarskiPlovdiv4000Bulgaria

The high performance of IoT technology in transportation networks has led to the increasing adoption of Internet of Vehicles(IoV)*** functional advantages of IoV include online communication services,accident prevention,cost reduction,and enhanced traffic *** these benefits,IoV technology is susceptible to cyber-attacks,which can exploit vulnerabilities in the vehicle network,leading to perturbations,disturbances,non-recognition of traffic signs,accidents,and vehicle *** paper reviews the state-of-the-art achievements and developments in applying Deep Transfer Learning(DTL)models for Intrusion Detection Systems in the Internet of Vehicles(IDS-IoV)based on anomaly ***-IoV leverages anomaly detection through machine learning and DTL techniques to mitigate the risks posed by *** systems can autonomously create specific models based on network data to differentiate between regular traffic and *** these techniques,transfer learning models are particularly promising due to their efficacy with tagged data,reduced training time,lower memory usage,and decreased computational *** evaluate DTL models against criteria including the ability to transfer knowledge,detection rate,accurate analysis of complex data,and *** review highlights the significant progress made in the field,showcasing how DTL models enhance the performance and reliability of IDS-IoV *** examining recent advancements,we provide insights into how DTL can effectively address cyber-attack challenges in IoV environments,ensuring safer and more efficient transportation networks.

关键词： Cyber-attacks internet of things internet of vehicles intrusion detection system

Recent antibacterial agents from biomass derivatives:Characteristics and applications

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Journal of Bioresources and Bioproducts 2024年第3期9卷 283-309页

作者： Nissa Nurfajrin Solihat Alif Faturahman Hidayat R.A.Ilyas senthil Muthu kumar Thiagamani Nur Izyan Wan Azeele Fahriya Puspita Sari Maya Ismayati Mohammad Irfan Bakshi Zaharaddeen N.Garba M.Hazwan Hussin Witta Kartika Restu Wasrin Syafii Harits Atika Ariyanta Widya Fatriasari Research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Kawasan KST SoekarnoJl Raya Bogor KM 46 Cibinong Bogor 16911Indonesia Department of Bioproducts and Biosystems School of Chemical EngineeringAalto UniversityEspoo 16300Finland Department of Chemical Engineering Faculty of Chemical and Energy EngineeringUniversiti Teknologi MalaysiaJohor 81310Malaysia Centre for Advanced Composite Materials Universiti Teknologi MalaysiaJohor 81310Malaysia Institute of Tropical Forestry and Forest Products Universiti Putra MalaysiaSerdang 43400Malaysia Centre of Excellence for Biomass Utilization Universiti Malaysia PerlisPerlis 02600Malaysia Department of Mechanical Engineering Kalasalingam Academy of Research and EducationKrishnankoil 626126India Institute of Bioproduct Development(IBD) Universiti Teknologi MalaysiaJohor 81310Malaysia Department of Chemistry Ahmadu Bello UniversityZaria 810211Nigeria Materials Technology Research Group(MaTReC) School of Chemical SciencesUniversiti Sains MalaysiaMinden 11800Malaysia Research Center for Chemistry National Research and Innovation Agency(BRIN)Kawasan Puspiptek SerpongSouth Tangerang 15314Indonesia Department of Forest Products Faculty of Forestry and EnvironmentIPB UniversityBogor 16680Indonesia Department of Pharmacy Gunadarma UniversityDepok 16424Indonesia Research Collaboration Center of Biomass-Based Nano Cosmetic In collaboration with National Research and Innovation Agency(BRIN)SamarindaEast KalimantanIndonesia

Enhancing awareness of personal cleanliness and antibacterial resistance has intensified the antibacterial substance request on consumable products. Antibacterial agents that have been commercialized nowadays are produced from inorganic and non-renewable substances. This provides several drawbacks, particularly against health and environmental issues. Therefore, many scientists work on substituting fossil-fuel-based antibacterial agents with natural ones such as from biomass. Biomass derivatives, natural abundances of biopolymers in the world, amount to major compounds including polysaccharides (cellulose, hemicellulose, and chitosan) and polyphenol (tannin and lignin) substances which are capable to combat the growth of Gram-positive bacteria and Gram-negative bacteria. To date, no report focuses on a deep understanding of antibacterial properties derived from biomass and the internal and external factors effects. This work provides that gap because comprehensive knowledge is necessary before applying biomass to the products. The potency of biomass derivatives as antibacterial additives is also summarized. Basic knowledge of antibacterial characteristics to the application in products is highlighted in this review. Besides, the discussion about challenges and future perspectives is also delivered.

关键词： Antibacterial Application Biomass derivatives Challenge Future perspectives

Ethnobotanical survey of medicinal plants used in the management of cancer and diabetes

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Journal of Traditional Chinese Medicine 2020年第6期40卷 1007-1017页

作者： Garima Singh Ajit kumar Passari Marcy D Momin Sakthivel Ravi Bhim Pratap Singh nachimuthu senthil kumar Department of Biotechnology Mizoram UniversityAizawl 796004India Department of Botany Pachhunga University CollegeAizawl 796001India Departamento de Biologia Molecular y Biotecnologia Instituto de Investigaciones BiomedicasUniversidad Nacional Autonoma de Mexico(UNAM)Ciudad de Mexico-04510Mexico Department of Agriculture&Environmental Sciences(AES) National Institute of Food Technology Entrepreneurship&Management(NIFTEM)SonepatHaryanaIndia

OBJECTIVE:To conduct an ethnobotanical survey and document the traditional anticancer and antidiabetic plants used by the local tribes of Mizoram,Northeast ***:A systematic survey was conducted in rural and urban areas of Mizoram by interviewing traditional practitioners,and cancer and diabetes patients.A detailed literature search was carried out using MEDLINE and SCOPUS and available literatures were selected and included in the *** use value(UV)of the selected plants was calculated based on the number of citations per species given by ***:Data was obtained for 201 traditional medicinal plants from Mizoram,Northeast *** plants were from 72 different families and belonged to 140 *** these,103 plants were reported for the first time as possessing either anticancer or antidiabetic potential,and 105 plants were identified that were used for the treatment of both *** plants(Phlogacanthus thysiformis,Solanum gilo and Lobelia angulata)with antidiabetic potential,and six plants(Dillenia scabrella,Circium sinesis,Eupatorium nodiflorum,Pratia begonifolia,Vernonia teres and Plantago erosa)with both as anticancer and antidiabetic potential were documented for the first ***:In this study,we documented several explored and unexplored medicinal plants that may be useful for the management of cancer and *** study suggests that there is a broad scope fordeveloping potent anticancer and antidiabetic agent from the flora of Mizoram,Northeast India.

关键词： Plants medicinal Antineoplastic agents Hypoglycemic agents Ethanobotanical survey Traditional knowledge

Highlighting novel genes associated with the classical Rett syndrome patient from India

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Genes & Diseases 2022年第6期9卷 1394-1396页

作者： Gomathi Mohan Ranjan Jyoti Sarma Mahalaxmi Iyer nachimuthu senthil kumar Balachandar Vellingiri UGC-RGNF Senior Research Fellow Human Molecular Cytogenetics and Stem Cell LaboratoryDepartment of Human Genetics and Molecular BiologyBharathiar UniversityCoimbatore 641046Tamil NaduIndia Department of Biotechnology Mizoram University(A Central University)Aizawl 796004MizoramIndia Livestock Farming&Bioresource Technology Tamil NaduIndia Human Molecular Cytogenetics and Stem Cell Laboratory Department of Human Genetics and Molecular BiologyBharathiar UniversityCoimbatore 641046Tamil NaduIndia

Rett syndrome(RTT)is a rare X-linked brain disorder predominantly in females,caused by mutations in Methyl-CpGBinding Protein2(MECP2)gene with the characteristic features of progressive developmental delay,severe intellectual disability,microcephaly,retarded growth,loss of communication abilities,loss of purposeful hand movements,abnormal walking or gait abnormalities,repetitive hand movements,abnormal breathing,irritability and abnormal behaviours.1 Over the last five years,more than eighty genes related to RTT were found using next generation sequencing.2 Here we presented a comprehensive clinical report of a 38-year-old RTT woman having de novo heterozygous Laminin Subunit Gamma 3 gene(LAMC3)mutation G>A(Chr9:133944387;p.C947Y)links with RTT neurological dysfunctions,brain malformations,reduced brain volume and hypoplasia of corpus *** new finding supports the possibility of targeting LAMC3 gene for rescuing the neuropathology of *** deleterious mutations found in genes such as,CACNA1B(rs4422842),CUBN(rs2271460),GPATCH3(rs779537923),TUBB1(rs463312),KCNJ5(rs768906222),VWA5A(rs551469534),DNAAF1(rs751148678),and PARP1(rs3219145)were unreported in RTT patients.

关键词： RTT lighting delay

Novel technique(Ramalingam technique)of port site retrograde intra renal surgery through exteriorized ureter during laparoscopy

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Asian Journal of Urology 2023年第3期10卷 372-375页

作者： Manickam Ramalingam Kallappan senthil Sivasankaran nachimuthu Urology Department Hindusthan HospitalCoimbatoreIndia

Occurrence of significant sized renal calculi along with ureteric pathology is not *** presented two patients:one with significant sized renal calculi along with lower ureteric stricture,and second case with significant sized renal calculi with primary obstructive mega ureter needing surgery for both the renal calculi and ureteric *** both patients laparoscopy was done,and the ureter was mobilised and divided just above the level of the pathology and exteriorised through the nearest sited port,and retrograde intra-renal surgery(RIRS)was done using flexible ureteroscope and *** laparoscopy was resumed,and ureteric reimplantation directly into the bladder or with a Boari flap was *** entire procedure was completed in a single *** novel technique of exteriorizing the ureter through the laparoscopic port site for flexible ureteroscopy in a case of lower ureteric pathology with renal stone is an advantageous option to manage both pathologies in a single *** has a better stone clearance than shock wave lithotripsy and less morbidity than percutaneous nephrolithotomy(PCNL).

关键词： ureter surgery bladder

Laparoscopic adenomectomy in BPH--Does it have a role today?

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Asian Journal of Urology 2018年第1期5卷 37-41页

作者： Ramalingam Manickam Sivasankaran nachimuthu senthil Kallappan Mizar GPai Uro-Nephro Centre Ganga Medical Centre&HospitalsRamnagarCoimbatoreIndia

Symptomatic benign prostatic hyperplasia(BPH)is managed medically worldwide,but transurethral resection of prostate(TURP)is the gold standard in refractory *** laser enucleation of prostate(HoLEP),laser vaporization are other options which are widely *** in larger glands which are more than 80 g,open adenomectomy is still *** adenomectomy is a minimally invasive option in such *** article explains about different techniques in minimally invasive adenomectomy and the role for this procedure *** simple prostatectomy(LSP)has a place in symptomatic,larger prostatic adenoma in the hands of experienced laparoscopic surgeons when open simple prostatectomy is needed.

关键词： Prostate BPH Adenomectomy Laparoscopy